Overview

Green tea is made from the Camellia sinensis plant. Its dried leaves and leaf buds are used to make several different teas, including black and oolong teas.

Green tea is prepared by steaming and pan-frying the Camellia sinensis leaves and then drying them. Green tea is not fermented, so it's able to maintain important molecules called polyphenols, which seem to be responsible for many of its benefits. It also contains caffeine.

People commonly use a US FDA-approved prescription product containing green tea for genital warts. As a drink or supplement, green tea is sometimes used for high cholesterol, high blood pressure, to prevent heart disease, and to prevent ovarian cancer. It is also used for many other conditions, but there is no good scientific evidence to support most of these uses.

Uses & Effectiveness

Likely Effective for

  • A sexually transmitted infection that can lead to genital warts or cancer (human papillomavirus or HPV). A specific green tea extract ointment (Polyphenon E ointment 15%) is available as a prescription product for treating genital warts. Applying the ointment for 10-16 weeks seems to clear these types of warts in 24% to 60% of patients.

Possibly Effective for

  • Heart disease. Drinking green tea is linked to a reduced risk of clogged arteries. The link seems to be stronger in males than in females. Also, people who drink at least three cups of green tea daily might have a lower risk of death from heart disease.
  • Cancer of the lining of the uterus (endometrial cancer). Drinking green tea is linked to a reduced risk of developing endometrial cancer.
  • High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Taking green tea by mouth seems to reduce low-density lipoprotein (LDL or "bad") cholesterol by a small amount.
  • Ovarian cancer. Regularly drinking tea green seems to reduce the risk for ovarian cancer.

There is interest in using green tea for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Green tea is commonly consumed as a beverage. Drinking green tea in moderate amounts (about 8 cups daily) is likely safe for most people. Green tea extract is possibly safe when taken for up to 2 years or when used as a mouthwash, short-term.

Drinking more than 8 cups of green tea daily is possibly unsafe. Drinking large amounts might cause side effects due to the caffeine content. These side effects can range from mild to serious and include headache and irregular heartbeat. Green tea extract also contains a chemical that has been linked with liver injury when used in high doses.

When applied to the skin: Green tea extract is likely safe when an FDA-approved ointment is used, short-term. Other green tea products are possibly safe when used appropriately.

Special Precautions and Warnings

When taken by mouth: Green tea is commonly consumed as a beverage. Drinking green tea in moderate amounts (about 8 cups daily) is likely safe for most people. Green tea extract is possibly safe when taken for up to 2 years or when used as a mouthwash, short-term.

Drinking more than 8 cups of green tea daily is possibly unsafe. Drinking large amounts might cause side effects due to the caffeine content. These side effects can range from mild to serious and include headache and irregular heartbeat. Green tea extract also contains a chemical that has been linked with liver injury when used in high doses.

When applied to the skin: Green tea extract is likely safe when an FDA-approved ointment is used, short-term. Other green tea products are possibly safe when used appropriately.

Pregnancy: Drinking green tea is possibly safe in amounts of 6 cups per day or less. This amount of green tea provides about 300 mg of caffeine. Drinking more than this amount during pregnancy is possibly unsafe and has been linked to an increased risk of miscarriage and other negative effects. Also, green tea might increase the risk of birth defects associated with folic acid deficiency.

Breast-feeding: Caffeine passes into breast milk and can affect a nursing infant. Closely monitor caffeine intake to make sure it is on the low side (2-3 cups per day) while breast-feeding. High intake of caffeine while breast-feeding can cause sleep problems, irritability, and increased bowel activity in breast-fed infants.

Children: Green tea is possibly safe for children when taken by mouth in amounts commonly found in foods and beverages, or when gargled three times daily for up to 90 days. There isn't enough reliable information to know if green tea extract is safe when taken by mouth in children. There's some concern that it might cause liver damage.

Anemia: Drinking green tea may make anemia worse.

Anxiety disorders: The caffeine in green tea might make anxiety worse.

Bleeding disorders: The caffeine in green tea might increase the risk of bleeding. Don't drink green tea if you have a bleeding disorder.

Heart conditions: When taken in large amounts, the caffeine in green tea might cause irregular heartbeat.

Diabetes: The caffeine in green tea might affect blood sugar control. If you drink green tea and have diabetes, monitor your blood sugar carefully.

Diarrhea: The caffeine in green tea, especially when taken in large amounts, can worsen diarrhea.

Seizures: Green tea contains caffeine. High doses of caffeine might cause seizures or decrease the effects of drugs used to prevent seizures. If you have ever had a seizure, don't use high doses of caffeine or caffeine-containing products such as green tea.

Glaucoma: Drinking green tea increases pressure inside the eye. The increase occurs within 30 minutes and lasts for at least 90 minutes.

High blood pressure: The caffeine in green tea might increase blood pressure in people with high blood pressure. But this effect might be less in people who consume caffeine from green tea or other sources regularly.

Irritable bowel syndrome (IBS): Green tea contains caffeine. The caffeine in green tea, especially when taken in large amounts, might worsen diarrhea in some people with IBS.

Liver disease: Green tea extract supplements have been linked to rare cases of liver damage. Green tea extracts might make liver disease worse. Talk to your doctor before taking green tea extract. Drinking green tea in normal amounts is still probably safe.

Weak bones (osteoporosis): Drinking green tea can increase the amount of calcium that is flushed out in the urine. This might weaken bones. If you have osteoporosis, don't drink more than 6 cups of green tea daily. If you are generally healthy and get enough calcium from your food or supplements, drinking about 8 cups of green tea daily doesn't seem to increase the risk of getting osteoporosis.

Interactions

    Moderate Interaction

    Be cautious with this combination

  • Adenosine (Adenocard) interacts with Green Tea

    Green tea contains caffeine. The caffeine in green tea might block the effects of adenosine, which is often used by doctors to do a test called a cardiac stress test. Stop consuming green tea at least 24 hours before a cardiac stress test.

  • Clozapine (Clozaril) interacts with Green Tea

    The body breaks down clozapine to get rid of it. The caffeine in green tea seems to decrease how quickly the body breaks down clozapine. Taking green tea along with clozapine can increase the effects and side effects of clozapine.

  • Dipyridamole (Persantine) interacts with Green Tea

    Green tea contains caffeine. The caffeine in green tea might block the effects of dipyridamole. Dipyridamole is often used by doctors to do a test on the heart called a cardiac stress test. Stop drinking green tea at least 24 hours before a cardiac stress test.

  • Ephedrine interacts with Green Tea

    Stimulant drugs speed up the nervous system. Green tea contains caffeine. Caffeine and ephedrine are both stimulant drugs. Taking green tea along with ephedrine might cause too much stimulation and sometimes serious side effects and heart problems. Do not take caffeine-containing products and ephedrine at the same time.

  • Lithium interacts with Green Tea

    The caffeine in green tea can increase how quickly the body gets rid of lithium. If you take products that contain caffeine and you take lithium, don't stop taking caffeine all at once. Decrease the daily dose of caffeine slowly. Stopping caffeine too quickly can increase the side effects of lithium.

  • Medications for diabetes (Antidiabetes drugs) interacts with Green Tea

    Green tea contains caffeine. Caffeine can either increase or decrease blood sugar. Diabetes medications are used to lower blood sugar. Taking some medications for diabetes along with caffeine might change the effects of the diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

  • Medications that can harm the liver (Hepatotoxic drugs) interacts with Green Tea

    Green tea extracts might harm the liver. Some medications can also harm the liver. Taking green tea extracts along with a medication that can harm the liver might increase the risk of liver damage.

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with Green Tea

    Green tea might slow blood clotting. Taking green tea along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

  • Nicotine interacts with Green Tea

    Stimulant drugs such as nicotine speed up the nervous system. The caffeine in green tea might also speed up the nervous system. Taking green tea along with stimulant drugs might cause serious problems, including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with caffeine.

  • Pentobarbital (Nembutal) interacts with Green Tea

    The stimulant effects of the caffeine in green tea can block the sleep-producing effects of pentobarbital.

  • Phenylpropanolamine interacts with Green Tea

    Green tea contains caffeine. Caffeine can stimulate the body. Phenylpropanolamine can also stimulate the body. Taking green tea and phenylpropanolamine together might cause too much stimulation and increase heartbeat and blood pressure and cause nervousness.

  • Riluzole (Rilutek) interacts with Green Tea

    Drinking green tea can decrease how quickly the body breaks down riluzole and increase the effects and side effects of riluzole.

  • Theophylline interacts with Green Tea

    Green tea contains caffeine. Caffeine works similarly to theophylline. Caffeine can also decrease how quickly the body gets rid of theophylline. Taking green tea along with theophylline might increase the effects and side effects of theophylline.

  • Verapamil (Calan, others) interacts with Green Tea

    Verapamil can decrease how quickly the body gets rid of caffeine. Drinking green tea and taking verapamil can increase the risk of caffeine side effects including jitteriness, headache, and an increased heartbeat.

  • Warfarin (Coumadin) interacts with Green Tea

    Green tea contains vitamin K. Vitamin K can reduce the effect of warfarin. But the amount of vitamin K in green tea is very small. So green tea is unlikely to interact with warfarin when used in moderation. Large amounts of green tea, such as 8 cups or more each day, should be avoided.

  • Medications for depression (MAOIs) interacts with Green Tea

    Green tea contains caffeine. There is some concern that caffeine can interact with certain medications, called MAOIs. If caffeine is taken with these medications, it might increase the risk for serious side effects including fast heartbeat and very high blood pressure. Some common MAOIs include phenelzine (Nardil), selegiline (Zelapar), and tranylcypromine (Parnate).

  • Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with Green Tea

    Some medications are changed and broken down by the liver. Green tea might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

  • Midazolam (Versed) interacts with Green Tea

    Green tea might decrease how quickly the body breaks down midazolam. Taking green tea along with midazolam might increase the effects and side effects of midazolam. But is not clear if this is a big concern.

  • Stimulant drugs interacts with Green Tea

    Stimulants, such as amphetamines and cocaine, speed up the nervous system. By speeding up the nervous system, stimulant medications can increase blood pressure and speed up the heartbeat. Green tea contains caffeine. Caffeine can also speed up the nervous system. Taking green tea along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure.

  • Bortezomib (Velcade) interacts with Green Tea

    Bortezomib is used in certain types of cancers. Green tea might interact with bortezomib and decrease its effects. If you take bortezomib, avoid taking green tea products.

  • Nadolol (Corgard) interacts with Green Tea

    Green tea might decrease how much nadolol the body absorbs. Taking green tea along with nadolol might decrease the effects of nadolol.

  • Medications moved by pumps in cells (Organic Anion-Transporting Polypeptide Substrates) interacts with Green Tea

    Some medications are moved in and out of cells by pumps. Green tea might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

  • Atorvastatin (Lipitor) interacts with Green Tea

    Green tea extract might decrease how much atorvastatin the body absorbs. Taking green tea extract along with atorvastatin might decrease the effects of atorvastatin.

  • Rosuvastatin (Crestor) interacts with Green Tea

    Taking green tea extract might change the amount of rosuvastatin in the blood. This might change the effects and side effects of rosuvastatin.

  • Water pills (Diuretic drugs) interacts with Green Tea

    Green tea contains caffeine. Caffeine, especially in large amounts, can reduce potassium levels in the body. "Water pills" can also decrease potassium in the body. Taking large amounts of caffeine along with "water pills" might decrease potassium in the body too much.

  • Fexofenadine (Allegra) interacts with Green Tea

    Green tea might decrease how much fexofenadine the body absorbs. Separate taking this medication from consuming green tea.

  • Nintedanib (Ofev) interacts with Green Tea

    Green tea might decrease how much nintedanib is in the body. It's not clear if this is a real concern.

  • Pioglitazone (Actos) interacts with Green Tea

    Green tea contains caffeine. Caffeine might increase the amount of pioglitazone that the body absorbs. Taking green tea might increase the effects and adverse effects of pioglitazone.

  • 5-Fluorouracil interacts with Green Tea

    Taking large amounts of green tea along with 5-fluorouracil might increase levels of 5-fluorouracil. This might increase the effects and side effects of 5-fluorouracil.

  • Medications moved by pumps in cells (P-Glycoprotein Substrates) interacts with Green Tea

    Some medications are moved in and out of cells by pumps. Green tea might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.

  • Carbamazepine (Tegretol) interacts with Green Tea

    Caffeine can decrease the effects of carbamazepine. Since green tea contains caffeine, taking green tea with carbamazepine might decrease the effects of carbamazepine.

  • Celiprolol (Celicard) interacts with Green Tea

    Green tea appears to decrease how much celiprolol is absorbed into the body. This might decrease the effects of celiprolol.

  • Ethosuximide (Zarontin) interacts with Green Tea

    Ethosuximide is a drug used to treat seizures. Caffeine in green tea can decrease the effects of ethosuximide. Taking green tea with ethosuximide might decrease the effects of ethosuximide. This might increase the risk of seizures.

  • Felbamate (Felbatol) interacts with Green Tea

    Felbamate is a drug used to treat seizures. The caffeine in green tea might decrease the effects of felbamate and increase the risk of seizures in some people.

  • Flutamide (Eulexin) interacts with Green Tea

    The body breaks down flutamide to get rid of it. The caffeine in green tea might decrease how quickly the body gets rid of flutamide. This could increase the effects and side effects of flutamide.

  • Imatinib (Gleevec) interacts with Green Tea

    Imatinib is used to treat certain types of cancer. Green tea appears to reduce how much imatinib gets into the body. This might decrease the effects of imatinib.

  • Lisinopril interacts with Green Tea

    Green tea appears to decrease how much lisinopril is absorbed into the body. This might decrease the effects of lisinopril.

  • Medications that decrease break down of other medications by the liver (Cytochrome P450 CYP1A2 (CYP1A2) inhibitors) interacts with Green Tea

    Green tea is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down green tea. This could change the effects and side effects of green tea.

  • Phenobarbital (Luminal) interacts with Green Tea

    Phenobarbital is a drug used to treat seizures. The caffeine in green tea might decrease the effects of phenobarbital and increase the risk of seizures in some people.

  • Phenytoin (Dilantin) interacts with Green Tea

    Phenytoin is a drug used to treat seizures. The caffeine in green tea can decrease the effects of phenytoin. Taking green tea with phenytoin might decrease the effects of phenytoin and increase the risk of seizures in some people.

  • Valproate interacts with Green Tea

    The caffeine in green tea might decrease the effects of valproate.

    Minor Interaction

    Be watchful with this combination

  • Medications for asthma (Beta-adrenergic agonists) interacts with Green Tea

    Green tea contains caffeine. Caffeine can stimulate the heart. Some medications for asthma can also stimulate the heart. Taking caffeine with some medications for asthma might cause too much stimulation and cause heart problems.

  • Alcohol (Ethanol) interacts with Green Tea

    The body breaks down the caffeine in green tea to get rid of it. Alcohol can decrease how quickly the body breaks down caffeine. Taking green tea along with alcohol might increase the effects and side effects of caffeine, including jitteriness, headache, and fast heartbeat.

  • Antibiotics (Quinolone antibiotics) interacts with Green Tea

    The body breaks down caffeine to get rid of it. Some antibiotics might decrease how quickly the body breaks down caffeine. Taking these antibiotics along with green tea can increase the risk of side effects including jitteriness, headache, increased heart rate, and other side effects.

  • Birth control pills (Contraceptive drugs) interacts with Green Tea

    Green tea contains caffeine. The body breaks down caffeine to get rid of it. Birth control pills can decrease how quickly the body breaks down caffeine. This might increase the risk for side effects from caffeine, such as jitteriness, headache, and fast heartbeat.

  • Cimetidine (Tagamet) interacts with Green Tea

    Green tea contains caffeine. The body breaks down caffeine to get rid of it. Cimetidine can decrease how quickly the body breaks down caffeine. Taking cimetidine along with green tea might increase the chance of caffeine side effects including jitteriness, headache, fast heartbeat, and others.

  • Disulfiram (Antabuse) interacts with Green Tea

    The body breaks down caffeine to get rid of it. Disulfiram can decrease how quickly the body gets rid of caffeine. Taking green tea along with disulfiram might increase the effects and side effects of caffeine, including jitteriness, hyperactivity, irritability, and others.

  • Estrogens interacts with Green Tea

    The body breaks down the caffeine in green tea to get rid of it. Estrogens can decrease how quickly the body breaks down caffeine. Taking estrogen and drinking green tea can increase the risk of caffeine side effects, including jitteriness, headache, fast heartbeat, and others.

  • Fluconazole (Diflucan) interacts with Green Tea

    Green tea contains caffeine. The body breaks down caffeine to get rid of it. Fluconazole might decrease how quickly the body gets rid of caffeine. Taking fluconazole along with green tea might increase the risk of caffeine side effects such as jitteriness, headache, fast heartbeat, and others.

  • Fluvoxamine (Luvox) interacts with Green Tea

    The body breaks down the caffeine in green tea to get rid of it. Fluvoxamine can decrease how quickly the body breaks down caffeine. Taking fluvoxamine along with green tea might increase the risk of caffeine side effects such as jitteriness, headache, fast heartbeat, and others.

  • Mexiletine (Mexitil) interacts with Green Tea

    Green tea contains caffeine. Mexiletine can decrease how quickly the body breaks down caffeine. Taking mexiletine along with green tea might increase the risk of caffeine side effects such as jitteriness, headache, fast heartbeat, and others.

  • Terbinafine (Lamisil) interacts with Green Tea

    Terbinafine can decrease how fast the body gets rid of caffeine. Taking green tea along with terbinafine can increase the risk of caffeine side effects including jitteriness, headache, increased heartbeat, and other effects.

  • Nicardipine (Cardene) interacts with Green Tea

    A chemical in green tea called EGCG might increase how much nicardipine is absorbed in the body. Green tea might increase the effects and side effects of nicardipine. But it's not clear if this is a real concern.

  • Metformin (Glucophage) interacts with Green Tea

    Green tea contains caffeine. Metformin can decrease how quickly the body breaks down caffeine. Taking green tea along with metformin might increase the effects and side effects of caffeine.

  • Methoxsalen (Oxsoralen) interacts with Green Tea

    Green tea contains caffeine. Methoxsalen can decrease how quickly the body breaks down caffeine. Taking caffeine along with methoxsalen might increase the risk of caffeine side effects such as jitteriness, headache, fast heartbeat, and others.

  • Phenothiazines interacts with Green Tea

    Green tea contains caffeine. Phenothiazines can decrease how quickly the body breaks down caffeine. Taking phenothiazines along with caffeine might increase the effects and side effects of caffeine.

  • Tiagabine (Gabitril) interacts with Green Tea

    Green tea contains caffeine. Taking caffeine over a long time period along with tiagabine can increase the amount of tiagabine in the body. This might increase the effects and side effects of tiagabine.

  • Ticlopidine (Ticlid) interacts with Green Tea

    Ticlopidine can decrease how quickly the body gets rid of caffeine. Taking green tea along with ticlopidine might increase the effects and side effects of caffeine, including jitteriness, hyperactivity, irritability, and others.

Dosing

Green tea is commonly consumed as a beverage. Green tea is also available in an FDA-approved ointment.

As a supplement, green tea powder and extracts have most often been used. Green tea products are typically standardized to the amount of polyphenols or antioxidants they provide. Green tea beverages typically contain 178-823 mg of specific polyphenols called catechins per cup. Green tea also contains caffeine. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.
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