This issue features articles by The Grainger Foundation US Frontiers of Engineering 2025 symposium participants. The technical sessions offered exciting glimpses into cutting edge developments across the fields of bioengineering, computer engineering, energy, and air transportation.

• President's Perspective: Building the Future of Engineering Together
• Guest Editors' Note: The Grainger Foundation Frontiers of Engineering 2025 Symposium
• Improving Motoneuron Function in Neurodegenerative Disease with Selective Electrical Stimulation of the Spinal Cord

This issue of The Bridge features cutting-edge perspectives on the rapid progress and innovation in advanced biomanufacturing for medicines.

• President's Perspective: The Importance of Engineering and the NAE
• Guest Editors' Introduction: Advanced Biomanufacturing for Medicines
• Transforming Manufacturing to Continue Leading the Innovation of Biopharmaceuticals

This issue features articles by The Grainger Foundation US Frontiers of Engineering 2024 symposium participants. The articles examine cutting-edge developments in microbiology and health, artificial intelligence, the gut-brain connection, and digital twins.

• Guest Editor's Note: The Grainger Foundation Frontiers of Engineering 2024 Symposium
• Achieving Impact through Human Behaviors and Community Engagement in Human Health Risk Assessment
• Designing Waste Management Systems to Prevent the Spread of Antibiotic Resistance: Challenges and Opportunities