Journal of Medical Internet Research
The leading peer-reviewed journal for digital medicine and health and health care in the internet age.
Editor-in-Chief:
Gunther Eysenbach, MD, MPH, FACMI, Founding Editor and Publisher; Adjunct Professor, School of Health Information Science, University of Victoria, Canada
Impact Factor 6.0 CiteScore 11.7
Recent Articles

The HIV epidemic in the United States disproportionately impacts gay, bisexual, and other men who have sex with men (MSM). Despite the effectiveness of HIV pre-exposure prophylaxis (PrEP) in preventing HIV acquisition, uptake among MSM remains suboptimal. Motivational interviewing (MI) has demonstrated efficacy at increasing PrEP uptake among MSM but is resource-intensive, limiting scalability. The use of artificial intelligence (AI), particularly large language models with conversational agents (i.e., “chatbots”) such as ChatGPT, may offer a scalable approach to delivering MI-based counseling for PrEP and HIV prevention.

While artificial intelligence (AI) holds significant promise for health care, excessive trust in these tools may unintentionally delay patients from seeking professional care, particularly among patients with chronic illnesses. However, the behavioral dynamics underlying this phenomenon remain poorly understood.

Accurately predicting ovarian response and determining the optimal starting dose of follicle-stimulating hormone (FSH) remain critical yet challenging for effective ovarian stimulation. Currently, there is a lack of a comprehensive model capable of simultaneously forecasting the number of oocytes retrieved (NOR) and assessing the risk of early-onset moderate-to-severe ovarian hyperstimulation syndrome (OHSS).


People with hand osteoarthritis represent a large patient group with limited access to recommended treatment. In recent years, there has been a notable shift in health care delivery, with increased use of digital technologies. The Happy Hands app (The University Information Technology Center [USIT]) is a digital self-management intervention developed to provide evidence-based treatment for people with hand osteoarthritis, with the goal of empowering them to self-manage their disease. Participants’ experiences and perceptions of using this digital intervention are crucial for the adoption and continued use of the Happy Hands app.

The transformation of digital health technologies has reshaped healthcare delivery in primary care. Despite these benefits, older adults remain among the most resistant users. Traditional technology adoption models may not fully capture this reluctance, which is shaped not only by usability challenges but also by emotional, psychological, and identity-related concerns. Innovation Resistance Theory (IRT) offers a complementary framework focused on barriers to adoption rather than solely on facilitators.

Meditation apps are increasingly popular, yet there is limited understanding of how much users actually engage with them. While meditation apps show promise for supporting mental health, engagement in real-world settings appears to be notably low. The patterns of app use and the factors that influence usage remain relatively unclear.


Social media platforms such as Reddit have become important spaces where individuals articulate their distress, seek support, and explore alternative ways of understanding mental health outside traditional institutional frameworks. These environments provide an opportunity to examine mental health discourse at scale, offering perspectives that extend beyond traditional clinical and research settings.
Preprints Open for Peer Review
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