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- Rapidly progressive kidney failure in an 82-year-old man with respiratory symptoms
The patient presented to the emergency department due to worsening dry cough, lower-extremity edema, and fatigue, all of which had begun about 2 weeks earlier.
- Artificial intelligence in medicine: How it works, how it fails
Using practical clinical examples, the authors explain the subset of artificial intelligence called large language models, highlighting the capabilities and limitations of these systems.
- Should potassium-competitive acid blockers replace proton pump inhibitors as first-line therapy for patients with severe (Los Angeles grade C or D) esophagitis?
Potassium-competitive acid blockers are reserved for patients who cannot tolerate proton pump inhibitors or who do not respond to them.
- Preventing cirrhosis: Why primary care clinicians should screen for liver disease in patients who drink heavily
Clinicians in the primary care setting can identify patients with heavy alcohol use and alcohol-related liver disease before they develop advanced liver damage.
- Profound xanthomas in a young man
The patient had a history of type 2 diabetes mellitus, hypercholesterolemia, and hypertriglyceridemia, with a fasting serum triglyceride level of 9,000 mg/dL.
- Xanthomas: A clue to undiagnosed lipid disorders
Given the wide availability of direct-to-consumer laboratory testing, it is reasonable to ask whether a working knowledge of xanthomas still matters for trainees and clinicians.
- A new direction in pain management?
It would be nice to have a treatment option for pain that is less limited by side effects, cognitive dysfunction, addiction potential, and red tape.
Right ventricular failure in a young manThe patient initially experienced dyspnea only on exertion, but over the 2 months before presentation it had progressed to shortness of breath at rest.
- Suzetrigine: A novel nonopioid systemic analgesic
The systemic sodium channel blocker suzetrigine may serve as another option for multimodal postoperative analgesia regimens and for managing acute nonsurgical pain.
Cleveland Clinic Journal of Medicine, published by Cleveland Clinic, provides busy clinicians with practical information to promote better patient care.