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Genome-wide screening reveals producer-cell modifications that improve virus-like particle production and delivery potency

Diana Ly, Hyewon Jang, Adhiraj Goel, Arnav Singh, View ORCID ProfileAditya Raguram
doi: https://doi.org/10.1101/2025.10.07.681010
Diana Ly
Whitehead Institute for Biomedical Research
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Hyewon Jang
Whitehead Institute for Biomedical Research
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Adhiraj Goel
Whitehead Institute for Biomedical Research
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Arnav Singh
Whitehead Institute for Biomedical Research
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Aditya Raguram
Whitehead Institute for Biomedical Research
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  • ORCID record for Aditya Raguram
  • For correspondence: araguram{at}wi.mit.edu
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Article Information

doi 
https://doi.org/10.1101/2025.10.07.681010
History 
  • February 2, 2026.

Article Versions

  • Version 1 (October 8, 2025 - 00:42).
  • Version 2 (October 8, 2025 - 21:18).
  • You are viewing Version 3, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Diana Ly,
  2. Hyewon Jang,
  3. Adhiraj Goel,
  4. Arnav Singh and
  5. Aditya Raguram1 (araguram{at}wi.mit.edu)
  1. Whitehead Institute for Biomedical Research
  1. ↵* Corresponding author; email: araguram{at}wi.mit.edu
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Posted February 02, 2026.
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Genome-wide screening reveals producer-cell modifications that improve virus-like particle production and delivery potency
Diana Ly, Hyewon Jang, Adhiraj Goel, Arnav Singh, Aditya Raguram
bioRxiv 2025.10.07.681010; doi: https://doi.org/10.1101/2025.10.07.681010
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Genome-wide screening reveals producer-cell modifications that improve virus-like particle production and delivery potency
Diana Ly, Hyewon Jang, Adhiraj Goel, Arnav Singh, Aditya Raguram
bioRxiv 2025.10.07.681010; doi: https://doi.org/10.1101/2025.10.07.681010

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