Our Impact

Pioneering.  Innovative.  Compassionate.

Our Impact

The great story of our animal-free journey

At Animal Free Research UK, thanks to your support, we’re pioneering innovative solutions to some of the most pressing health challenges of our time. From cancer to Alzheimer’s disease, COVID-19 to diabetes, and beyond, we’re leaving no stone unturned in our quest for animal-free alternatives.

Our passionate researchers aren’t just making waves; they’re making history. With breakthroughs published in prestigious journals and presentations at top-tier conferences, we’re boldly pushing the boundaries of human-relevant research.

But this is just the beginning. Together, with you by our side, we’re building a future fueled by innovation, compassion, and unwavering determination.

Together, we’re rewriting the story of medical research, one breakthrough at a time.

Funding innovation across the UK

Since 1970, Animal Free Research UK has awarded over £11.5M in grants to fund 300 pioneering medical research projects that place ethics at the heart of the science of human disease.

View map of our projects

11500000

Awarded to fund animal-free research grants

300

projects funded across the UK

69

Student researchers trained at our Summer Schools

Some of our key milestones

1

1975

We launch the first ever cell culture study of eye irritancy, offering an alternative to the controversial Draize eye test on rabbits
2

1980

The World Health Organisation approves a cell culture alternative to polio vaccine tests in monkeys, championed by us
3

1986

We help replace the 110-year old Cruelty to Animals Act 1876. The new Animals (Scientific Procedures) Act 1986 marks a major shift in policy
4

1997

We help open the first UK Human Tissue Bank
5

1998

Transcranial magnetic stimulation (TMS) is used to replace invasive experiments on monkeys and now used worldwide
6

2006

Our in vitro micronucleus test is approved to replace animals for mutagenicity studies
7

2012

We fund the first non-animal models of bipolar and Alzheimer’s disease
8

2016/2019

We launch the Animal Replacement Centres of Excellence (ARC 1.0 and ARC 2.0)
9

2020

Professor Lorna Harries and her team from the ARC 2.0 works on an animal-free test that identifies if someone is still infectious with Covid-19
10

2021

Scientists at our ARC 2.0 made a major discovery in our understanding of diabetes, using human cells. The work at ARC 2.0 has been ground-breaking in finding the gene responsible for changing insulin-producing beta cells in response to ageing – which could lead to new diabetes treatments
11

2021

We launched our Pioneer Award, celebrating the outstanding contribution of trailblazing scientists who conduct research without using animals. The inaugural award was presented to Dr Don Ingber, the founding director of Harvard University’s Wyss Institute for Biologically Inspired Engineering
12

2022

We teamed up with the Alliance for Human Relevant Science and Dutch partners from the Transition Programme for Innovation to launch Britain’s first Helpathon to help researchers make the shift towards animal-free methods
13

2022

With Cruelty Free International and OneKind, we delivered our #TargetZero petition to the Government signed by over 100,000 people, which led to a parliamentary debate on phasing out animal research
14

2022

We launched our very own podcast, the Animal Free Labcast, hosted by our fantastic CEO, Carla Owen. Each episode features inspiring conversations with special guests, including our incredible patron, Dame Joanna Lumley
15

2023

We hosted an event at the prestigious Royal Society in London, uniting leading experts and stakeholders in drug-induced liver injury (DILI). This gathering laid the foundation for a collaborative community committed to driving regulatory changes around drug testing and advancing DILI prevention
16

2023

Leading professor of Evidence-Based Transition to Animal-free Innovations at Utrecht University, Dr Merel Ritskes-Hoitinga, was awarded Animal Free Research UK's Pioneer Medal. Dr Adrian Biddle of Queen Mary University London was also awarded the inaugural Outstanding Scientist Award, and Sophie O’Kane of Karolinska Institutet was the first to receive the Early Career Scientist Award
17

2024

Steve Race MP introduced the Animals in Medical Research (Prohibition) Bill, based on Herbie’s Law, on our behalf – calling for an end to the use of animals in medical research, and a requirement for non-animal methods to be used instead.
18

2024

We launched our new initiative, the Centre for Human Specific Research!
19

2025

We held our first joint science conference, titled “Best Practice in Non-Animal Research Methods”. The conference brought together researchers to share expertise and experience, showcase innovative technologies and approaches in action, and reflect on scientific progress that is helping to replace animal use across research and testing.
20

2025

Seven incredible celebrities (Pete Wicks, Deborah Meaden, Kirsty Gallacher, Diane Morgan, Pandora Christie, Russell Kane and Jake Lambert) united to mark World Animal Free Research Day, and were joined by two beagles – Luna and Elvis – in a photoshoot by world-renowned photographer Rankin. The celebrities wore t-shirts featuring an illustration by award winning illustrator Emily Sutton to show their support for a brighter future without animal testing.
White rabbits
Animal Free Research UK
Animal Replacement Centre logo
Dr Donald Ingber is presented with the 2022 Pioneer Award by Carla Owen
Herbie's Law - Animal Free Research UK

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Grantholder Papers:

Scientific papers published as a result of Animal Free Research UK funded projects and researchers