You can try using an HTML table and use some PHP code in the columns – make sure to close PHP before and after the HTML. Change widths as you wish. I did inline CSS but you can also enqueue your CSS in a file if you prefer.
<table style="width: 100%;">
<tr>
<td style="width: 50%;">
Column 1
</td>
<td style="width: 50%;">
Column 2
</td>
</tr>
</table>
ok, but the code of all the custom fields is in the file functions, it’s a lot of stuff, how can I “order” to this html to work on the edit post page, right down the description default area of each post? thank you
Sorry. I misunderstood. What you are asking then is how to split the metabox that has the custom fields into multiple columns. I am not exactly sure how to do that as I have not done this myself. Without more details, such as exactly how it’s coded now, it would be difficult to know which approach to take to make this happen.