-abine

see -arabine, -citabine

USAN

-ac (x)

anti-inflammatory agents, ibufenac derivatives

A.4.2.0

(USAN: anti-inflammatory agents (acetic acid derivatives))

(a)

aceclofenac (52), alclofenac (23), amfenac (38), anirolac (52), bendazac (22), bromfenac (55), cinfenoac (41), clidanac (39), clofurac (42), clopirac (30), dexpemedolac (71), diclofenac (28), eltenac (53), etodolac (45), felbinac (54), fenclofenac (30), fenclorac (33), fentiazac (32), furofenac (40), ibufenac (14), isoxepac (37), ketorolac (51), lexofenac (38), nepafenac (78), oxepinac (36), oxindanac (54), pemedolac (58), (quinclorac, ISO name for a herbicide), sulindac (33), tianafac (31), tifurac (57), tiopinac (40), zomepirac (37)

-zolac: bufezolac (39), isofezolac (39), lonazolac (34), mofezolac (64), pirazolac (43), trifezolac (34)

(b)

amtolmetin guacil (65), bufexamac (20) (anti-inflammatory; acetohydroxamic acid group instead of acetic acid group)

(c)

clamidoxic acid (17), fenclozic acid (22), metiazinic acid (20), prodolic acid (29), tolmetin (23)

TRS 581

-acetam

see -racetam

USAN

-actide (x)

synthetic polypeptides with a corticotropin-like action

Q.1.1.1

(USAN: synthetic corticotropins)

(a)

alsactide (45), codactide (24), giractide (29), norleusactide (18), seractide (31), tetracosactide (18), tosactide (24), tricosactide (44)

TRS 581

BAN, USAN

-adol (x) or -adol-

analgesics (14th Report, 1967)

A.4.1.0

A.4.2/3.0

(USAN: analgesics (undefined group))

(a)

A.4.1.0: acetylmethadol (5), alimadol (39), alphacetylmethadol (5), alphamethadol (5), axomadol (87), betacetylmethadol (5), betamethadol (5), levacetylmethadol (27), noracymethadol (12), tapentadol (87)

A.4.2/3.0: apadoline (74), asimadoline (74), bromadoline (49), ciprefadol (41), ciramadol (39), cloracetadol (16), dibusadol (24), dimenoxadol (7), diproxadol (34), enadoline (68), filenadol (47), flumexadol (36), fluradoline (48), gaboxadol (48), levonantradol (43), lorcinadol (57), moxadolen (45), (deleted in List 48: moxifadol (47)), myfadol (17), nafoxadol (50), nantradol (42), nerbacadol (56), oxapadol (40), picenadol (47), pinadoline (50), pipradimadol (42), pipramadol (42), pravadoline (60), vadoline (60), profadol (20), radolmidine (82), ruzadolane (71), spiradoline (53), tazadolene (52), tolpadol (48), tramadol (22), veradoline (47)

(b)

alfadolone (27), hexapradol (12) (CNS stimulant), nadolol (34), quinestradol (15) (estrogenic)

(c)

A.4.1.0: dimepheptanol (5)

-adom

analgesics, tifluadom derivatives

A.4.3.0

(a)

lufuradom (50), tifluadom (48)

-afenone

antiarrhythmics, propafenone derivatives

H.2.0.0

(a)

alprafenone (62), berlafenone (63), diprafenone (48), etafenone (19), propafenone (29)

USAN

-aj-

antiarrhythmics, ajmaline derivatives

H.2.0.0

(a)

detajmium bitartrate (34), lorajmine (34), prajmalium bitartrate (23)

-al (d)

aldehydes

(deleted from General Principles in 14th Report)

USAN

-aldrate

antacids, aluminium salts

N.5.2.0

(a)

carbaldrate (53), potassium glucaldrate (14), sodium glucaspaldrate (17), magaldrate (49), simaldrate (15)

USAN

-alol

see -olol

-alox

see -ox

USAN

andr (d)

steroids, androgens

Q.2.3.0

(USAN: -andr- androgens)

(a)

i. andr: androstanolone (4), methandriol (1), nandrolone (22), norethandrolone (6), ovandrotone albumin (52), silandrone (18)

ii. -stan- (d): androstanolone (4), drostanolone (13), epitiostanol (31), mestanolone (10), stanozolol (18), epostane (51) (contraceptive)

iii. -ster- (d): calusterone (23), cloxotestosterone (12), fluoxymesterone (6), mesterolone (15), methyltestosterone (4), oxymesterone (12), penmesterol (14), prasterone (23), testosterone (4), testosterone ketolaurate (16), tiomesterone (14)

(b)

i. andr: oxandrolone (12), propetandrol (13)

iii. ster: aldosterone (6), bolasterone (13), dihydrotachysterol (1), dimethisterone (8), ethisterone (4), norethisterone (6), norvinisterone (6), stercuronium iodide (21) (neuromuscular blocking agent)

(c)

metandienone (12), oxymetholone (11), trestolone (25) (antineoplastic androgen)

TRS 581

-anide

-etanide

diuretics, piretanide derivatives

N.1.2.0

(USAN: diuretics (piretanide group))

(a)

bumetanide (24), piretanide (33)

(c)

besunide (30)

-oxanide

antiparasitic, salicylanilides and analogues

S.3.0.0

(a)

bromoxanide (31), clioxanide (19), rafoxanide (24)

thioanalogues: brotianide (24)

related: diloxanide (8), nitazoxanide (45)

(b)

closantel (36), flurantel (25), niclosamide (13), resorantel (23), salantel (29)

(c)

oxyclozanide (16)

other -anides:

aurothioglycanide (1) (anti-arthritic; gout-remedy), ceforanide (39) (antibiotic), oglufanide (86) (immunomodulator), polihexanide (24) (antibacterial), tiprostanide (48) (antihypertonic)

BAN, USAN

-anserin

serotonin receptor antagonists (mostly 5-HT₂)

C.7.0.0

(USAN: serotonin receptor antagonists (undefined group))

(a)

adatanserin (70), altanserin (50), blonanserin (76), butanserin (51), eplivanserin (80), fananserin (69), flibanserin (75), ketanserin (46), lidanserin (62), pelanserin (57), seganserin (56), tropanserin (55)

(b)

serotonin receptor antagonists, psychoactive: cinanserin (17), glemanserin (68), mianserin (20), ritanserin (51)

USAN

-antel

anthelminthics (undefined group)

S.3.1.0

(a)

amidantel (40), carbantel (35), closantel (36), epsiprantel (57), febantel (38), flurantel (25), morantel (22), oxantel (31), pexantel (22), praziquantel (34), pyrantel (17), resorantel (23), salantel (29), zilantel (33), antelmycin (15)

TRS 581

-apine

see -pine

USAN

-(ar)abine

arabinofuranosyl derivatives

L.4.0.0/S.5.3.0

(USAN: -arabine: antineoplastic arabinofuranosyl derivatives)

(a)

ancitabine (36), capecitabine (73), cytarabine (14), decitabine (61), emtricitabine (80), enocitabine (46), fazarabine (56), fiacitabine (59), fludarabine (48), flurocitabine (38), galocitabine (65), gemcitabine (62), ibacitabine (57), nelarabine (80), vidarabine (23), zalcitabine (66)

(c)

S.5.3.0: ribavirin (31)

USAN

-arit

antiarthritic substances, acting like clobuzarit and lobenzarit, (mechanism different from anti-inflammatory type substances, e.g. -fenamates or -profens)

A.4.2.0

(USAN: antirheumatic substances, acting similarly to lobenzarit)

(a)

actarit (62), bindarit (64), clobuzarit (44), lobenzarit (46), romazarit (60)

USAN

-arol (d)

anticoagulants, dicoumarol derivatives

I.2.1.0

(USAN: anticoagulants (dicoumarol type))

(a)

acenocoumarol (6), clocoumarol (31), coumetarol (13), dicoumarol (23), tioclomarol (31), xylocoumarol (15)

(b)

cloridarol (29) (coron. vasodil.), fluindarol (16) (anticoag. of indonedione-type)

(c)

diarbarone (15), ethyl biscoumacetate (4), phenprocoumon (11), warfarin (23)

TRS 581

-arone

amiodarone (16) (anti-arrhythmic), benzarone (13), benzbromarone (13) (uricosuric), benziodarone (11), brinazarone (64) (calcium channel blocker), bucromarone (48) (antiarrhythmic), diarbarone (15), dronedarone (75) (anti-anginal, antiarrhythmic), etabenzarone (17), fantofarone (65) (calcium channel blocker), furidarone (19), inicarone (27), mecinarone (30), pyridarone (16), rilozarone (58)

arte-

antimalarial agents, artemisinin related compounds

S.3.3.0

(a)

artemether (61), artemisinin (56), artemotil (80), artenimol (81), artesunate (61), arteflene (70)

USAN

-ase

enzymes

W.0.0.0

(a)

agalsidase alfa (84), agalsidase beta (84), alglucerase (68), brinase (22), cocarboxylase (1), dornase alfa (70), eufauserase (84), hyalosidase (50), hyaluronidase (1), idusulfase (87), kallidinogenase (22), ocrase (28), pegaspargase (64), penicillinase (10), promelase (47), rizolipase (22), serrapeptase (31), sfericase (40), streptodornase (6), streptokinase (6), tilactase (50), urokinase (48)

(c)

batroxobin (29), bromelains (18), chymopapain (26), chymotrypsin (10), defibrotide (44), orgotein (31), sutilains (18), ubidecarenone (48)

Classification of enzymes

I

proteinase

(a)

with -ase suffix:

(INN)

(origin)

(use, action)

brinase (22)

Aspergillus oryzae

fibrinolytic

kallidinogenase (22)

pancreas or urine of mammals

splitting kinin, kallidin from kininogen (vasodilator)

ocrase (28)

Aspergillus ochraceus

fibrinolytic (topically: cleaning wounds)

pegaspargase (64)

asparaginase

promelase (46)

Aspergillus melleus

proteinase (chronic bronchitis)

rasburicase (81)

Aspergillus flavus

urate oxidase (hyperuricaemia)

serrapeptase (31)

Serratia sp. E15

proteinase (chronic paranasal sinusitis etc.)

sfericase (40)

Bacillus sphaericus

proteinase (chronic paranasal sinusitis etc.)

streptokinase (6)

Streptococcus haemolyticus

changing plasminogen into plasmine (activator of fibrinolysis)

urokinase (48)

human origin

plasminogen activator

urokinase alfa (27)

recombinant material

plasminogen activator

(b)

without -ase suffix:

batroxobin (29)

the venom of the serpent Bothopsatrox

thrombin like enzyme

bromelains (18)

Ananas comosus Merr.

fibrin depolymerizing (antiinflammatory)

chymopapain (26)

papaya late

proteolytic (chemonucleosis)

chymotrypsin (10)

mammalian pancreas

proteolytic (antiinflammatory, antioedema)

defibrotide (44)

mammalian pancreas

proteolytic (antiinflammatory, antioedema)

sutilains (18)

Bacillus subtilis

proteolytic

II

-lipase

rizolipase (22)

Rhizopus arrhizus var. Delemar

lipase

III

co-enzymes

cocarboxylase (1)

chemically defined

co-enzyme in the metabolism of pyruvic acid

ubidecarenone (48)

chemically defined

naturally occurring co-enzyme, a component in the electron transfer system in mitochondria (congestive heart failure)

USAN

IV

-dismase enzymes with superoxide dismutase activity

(USAN: superoxide dismutase activity (exception: orgotein))

(a)

ledismase (70), sudismase (58)

(c)

isomerase

orgotein (31)

mammalian tissue (liver, red blood cell etc.)

superoxide dismutase activity (anti-inflammatory)

pegorgotein (72)

V

-diplase plasminogen activator combined with another enzyme

amediplase (79)

USAN

VI

-teplase tissue-type-plasminogen activators

(a)

alteplase (59), anistreplase (59), desmoteplase (80), duteplase (62), lanoteplase (76), monteplase (71), nateplase (73), pamiteplase (78), reteplase (69), silteplase (65), tenecteplase (79)

USAN

VII

-uplase urokinase-type-plasminogen activators

(a)

nasaruplase (68), nasaruplase beta (85), saruplase (58)

VIII

others

agalsidase alfa (84)

human origin

treatment of deficiency of alpha-galactosidase activity (Fabry’s disease)

agalsidase beta (84)

hamster

treatment of deficiency of alpha- galactosidase activity (Fabry’s disease)

alfimeprase (85)

Agkistrodon contrix contrix

antithrombotic

dornase alfa (70)

human origin

treatment of cystic fibrosis

epafipase (85)

human origin

antiallergic, antiasthmatic

eufauserase (84)

Euphausia Superba

digests proteins and selected cell surface adhesion molecules (wound healing; viginal/oral candidosis)

hyalosidase (50)

hyaluronoglucosaminidase (treatment of myocardial infarction)

hyaluronidase (1)

various origins

depolymerizing hya luronic acid (cellular diffusion factor)

idusulfase (87)

treatment of Hunter Syndrome (Mucopolysaccharidosis Type II), degrades glycosaminoglycans heparan and dermatan sulfate

imiglucerase (72)

human origin (placenta isoenzyme)

laronidase (85)

human origin

penicillinase (10)

Bacillus cereus

inactivating penicillin

ranpirnase (81)

Rana pipiens

ribonuclease (antineoplastic)

streptodornase (6)

Streptococcus haemolyticus

hydrolysing desoxyribonucleoprotein

tilactase (50)

β-D-glactosidase

BAN, USAN

-ast (x)

antiasthmatic, antiallergics, not acting primarily as antihistaminics

K.0.0.0

(BAN: antiasthmatics, antiallergics when not acting primarily as antihistamines)

(USAN: antiasthmatics or antiallergic substances not acting primarily as antihistamines)

(a)

acitazanolast (72), acreozast (77), andolast (67), asobamast (63), ataquimast (82), bamaquimast, (76), batebulast (66), binizolast (60), bunaprolast (60), cilomilast (82), dametralast (54), dazoquinast (54), doqualast (48), eclazolast (55), eflumast (61), enofelast (67), enoxamast (52), fenprinast (48), filaminast (75), ibudilast (58), idenast (58), lirimilast (85), loxanast (46), melquinast (62), ontazolast (72), oxalinast (49), pemirolast (61), piclamilast (73), picumast (47), pirodomast (64), quazolast (55), raxofelast (68), repirinast (55), revenast (51), roflumilast (77), scopinast (76), suplatast tosilate (64), tazanolast (59), tetrazolast (67), tiacrilast (52), tibenelast (58), tioxamast (53), tiprinast (50), tofimilast (85), tranilast (46), zaprinast (46)

-lukast

leukotriene receptor antagonist

(a)

ablukast (61), cinalukast (70), iralukast (70), montelukast (73), pobilukast (70), pranlukast (67), ritolukast (64), sulukast (63), tomelukast (59), verlukast (65), zafirlukast (71)

-trodast

thromboxane A₂ receptor antagonists, antiasthmatics

(a)

imitrodast (70), seratrodast (70)

(c)

bufrolin (34), oxarbazole (38), pirolate (44)

BAN, USAN

-astine (x)

antihistaminics

G.2.0.0

(BAN: antihistamines, not otherwise classifiable)

(USAN: antihistaminics (histamine-H₁ receptor antagonists))

(a)

acrivastine (51), alinastine (74), azelastine (36), barmastine (59), bepiastine (19), bepotastine (78), bilastine (82), cabastinen (50), carebastine (52), clemastine (22), dorastine (23), ebastine (52), emedastine (59), epinastine (55), flezelastine (67), levocabastine (50), linetastine (74), mapinastine (72), mizolastine (64), moxastine (15), noberastine (59), octastine (37), perastine (15), piclopastine (22), rocastine (57), setastine (39), talastine (18), temelastine (54), zepastine (26)

(b)

cloperastine (18) (antitussive), vinblastine (12) (vinca-alkaloid)

(c)

astemizole (45), carbinoxamine (4)

-azam

see - azepam

USAN

-azenil

benzodiazepine receptor antagonists/agonists (benzodiazepine derivatives)

(a)

bretazenil (60), flumazenil (55), iomazenil ¹²³I (66), sarmazenil (59)

(b)

nabazenil (49)

-carnil

benzodiazepine receptor antagonists/agonists (carboline derivatives)

(a)

abecarnil (60), gedocarnil (61)

-quinil

benzodiazepine receptor partial agonists (quinoline derivatives)

(a)

lirequinil (72), terbequinil (63)

BAN, USAN

-azepam (x)

diazepam derivatives

C.1.0.0

(BAN: substances of the diazepam group)

(USAN: antianxiety agents (diazepam type))

(a)

bromazepam (22), camazepam (30), carburazepam (39), cinolazepam (46), clonazepam (22), cyprazepam (16), delorazepam (40), diazepam (12), doxefazepam (43), elfazepam (36), fletazepam (31), fludiazepam (36), flunitrazepam (24), flurazepam (20), flutemazepam (58), flutoprazepam (45), fosazepam (27), halazepam (29), iclazepam (37), lorazepam (23), lormetazepam (38), meclonazepam (44), medazepam (20), menitrazepam (22), metaclazepam (46), motrazepam (31), nimetazepam (26), nitrazepam (16), nordazepam (39), nortetrazepam (20), oxazepam (13), pinazepam (32), pivoxazepam (34), prazepam (14), proflazepam (31), quazepam (36), reclazepam (53), sulazepam (14), temazepam (22), tetrazepam (17), tolufazepam (51), tuclazepam (40), uldazepam (30)

not true benzodiazepines: bentazepam (33), clotiazepam (30), lopirazepam (36), premazepam (45), ripazepam (33), zolazepam (28)

related: adinazolam (45), alprazolam (30), arfendazam (39), clazolam (29), climazolam (51), clobazam (25), clobenzepam (25), cloxazolam (29), ecopipam (80), estazolam (31), flutazolam (32), haloxazolam (38), ketazolam (26), lofendazam (36), loprazolam (44), mexazolam (40), midazolam (40), nefopam (25), oxazolam (25), razobazam (52), tofisopam (26), trepipam (38), triazolam (30), triflubazam (28), zapizolam (43), zomebazam (49)

(c)

brotizolam (40), chlordiazepoxide (11), ciclotizolam (40), demoxepam (23), dipotassium clorazepate (17), ethyl carfluzepate (43), ethyl dirazepate (44), ethyl loflazepate (43), etizolam (40), potassium nitrazepate (17)

TRS 581

not related: anti-anx.: fenobam (36), muscle relax.: xilobam (36)

-azepide

cholecystokinin receptor antagonist

J.1.0.0

(a)

devazepide (62), pranazepide (75), tarazepide (68)

(c)

lorglumide (56)

USAN

-azocine

narcotic antagonists/agonists related to 6,7-benzomorphan

A.4.1.0

(USAN: narcotic antagonists/agonists related to 6,7-benzo-morphan)

(a)

anazocine (30), bremazocine (43), butinazocine (53), carbazocine (16), cogazocine (36), cyclazocine (14), eptazocine (45), gemazocine (29), ibazocine (36), ketazocine (34), metazocine (9), moxazocine (38), pentazocine (14), phenazocine (9), quadazocine (54), tonazocine (46), volazocine (19)

(b)

streptozocin (33)

TRS 581

-azolam

see -azepam

USAN

-azoline

antihistaminics or local vasoconstrictors, antazoline derivatives

E.4.0.0

(USAN: antihistaminics or local vasoconstrictors of the antazoline group)

(a)

antazoline (1), cilutazoline (61), cirazoline (38), clonazoline (18), coumazoline (26), domazoline (30), fenoxazoline (12), indanazoline (42), metrafazoline (33), naphazoline (1), nemazo-line (63), oxymetazoline (13), phenamazoline (6), prednazoline (22), tefazoline (24), tinazoline (39), tramazoline (15), xylometazoline (8)

(b)

cefazolin (25) (antibiotic)

(c)

tetryzoline (6), metizoline (22)

TRS 581

-azone

see -buzone

USAN

-azosin

antihypertensive substances, prazosin derivatives

H.3.0.0

(USAN: antihypertensives (prazosin type))

(a)

bunazosin (50), doxazosin (47), neldazosin (60), prazosin (22), quinazosin (17), terazosin (44), tiodazosin (41), trimazosin (31)

related: alfuzosin (49), tamsulosin (65), tipentosin (55)

BAN, USAN

-bactam

β-lactamase inhibitors

S.6.5.0

(a)

brobactam (53), sulbactam (44), tazobactam (60)

(c)

clavulanic acid (44)

BAN, USAN

-bamate

tranquillizers, propanediol and pentanediol derivatives

C.1.0.0

(a)

cyclarbamate (13), meprobamate (6), nisobamate (21), pentabamate (13), tybamate (14)

(b)

difebarbamate (16), febarbamate (12), lorbamate (24), phenprobamate (10)

(c)

mebutamate (12), metaglycodol (12) (not a carbamate)

TRS 581

BAN, USAN

barb (d)

hypnotics, barbituric acid derivatives

A.2.1.0

(BAN: -barb, -barb-: for barbiturates)

(USAN: -barb; or -barb-: barbituric acid derivatives)

(a)

allobarbital (1), amobarbital (1), aprobarbital (1), barbexa-clone (16), barbital (4), barbital sodium (4), benzobarbital (25), brallobarbital (41), carbubarb (14), cyclobarbital (1), difebarbamate (16), eterobarb (32), febarbamate (12), heptabarb (14), hexobarbital (1), methylphenobarbital (1), nealbarbital (11), pentobarbital (1), phenobarbital (4), phenobarbital sodium (4), probarbital sodium (1), proxibarbal (33), secbutabarbital (12), secobarbital (4), tetrabarbital (4), thialbarbital (4), thiotetrabarbital (4), vinbarbital (1)

(c)

butalbital (4), buthalital sodium (8), metharbital (1), methitural (6), methohexital (8), phetharbital (10), talbutal (17), thiopental sodium (4), vinylbital (12) prazitone (19) (barbituric acid derivative used as antidepressive), bucolome (17) (barbituric acid derivative used as anti-inflammatory uricosuric)

TRS 581

-bendan

see -dan

USAN

-bendazole

anthelminthics, tiabendazole derivatives

S.3.1.0

(USAN: anthelmintics (tiabendazole type))

(a)

albendazole (35), albendazole oxide (56), bisbendazole (29), cambendazole (24), ciclobendazole (31), dribendazole (49), etibendazole (49), fenbendazole (29), flubendazole (34), lobendazole (28), luxabendazole (52), mebendazole (24), oxibendazole (30), parbendazole (19), subendazole (31), tiabendazole (13), triclabendazole (45)

(b)

bendazol (12) (vasodilator, also benzimidazole derivative)

L.0.0.0: nocodazole (36), procodazole (36) (also benzimidazole derivative)

c)

oxfendazole (35), tioxidazole (39)

related: furodazole (37) (S.3.1.0)

TRS 581

BAN, USAN

bol (x)

anabolic steroids

M.4.1.0

(BAN: steroids, anabolic)

(USAN: bol- or -bol-: anabolic steroids)

(a)

bolandiol (16), bolasterone (13), bolazine (21), boldenone (20), bolenol (19), bolmantalate (16), clostebol (22), enestebol (22), formebolone (31), furazabol (16), mebolazine (21), mesabolone (29), metribolone (17), mibolerone (27), norboletone (15), norclostebol (22), oxabolone cipionate (14), quinbolone (14), roxibolone (40), stenbolone (17), tibolone (22), trenbolone (24)

(c)

ethylestrenol (13), hydroxystenozole (10), metandienone (12), metenolone (12), oxandrolone (12), propetandrol (13), tiomesterone (14)

-bradine

bradycardic agents

H.0.0.0

(a)

cilobradine (63), ivabradine (75), zatebradine (62)

-brate

see -fibrate

USAN

-buzome (x)

anti-inflammatory analgesics, phenylbutazone derivatives

A.4.2.0

(a)

feclobuzone (27), kebuzone (19), pipebuzone (25), suxibuzone (24), tribuzone (33)

-butazone

(USAN: anti-inflammatory analgesics of the phenylbutazone type)

mofebutazone (15), oxyphenbutazone (8), phenylbutazone (1)

-azone

aminophenazone (13), bisfenazone (33), famprofazone (21), morazone (12), nifenazone (15), nimazone (20), niprofazone (29), phenazone (4), propyphenazone (1), sulfinpyrazone (8)

-zone

clofezone (17), proxifezone (24)

related:

azapropazone (18), benhepazone (15), bumadizone (24), cinnopentazone (17), isamfazone (37), metamfazone (12), osmadizone (26), ruvazone (26)

(c)

benzpiperylone (12), butopyrammonium iodide (8), dibupyrone (17), metamizole sodium (53), metazamide (16), piperylone (11)

TRS 581

BAN, USAN

-caine (x)

local anaesthetics

D.1.0.0

(a)

ambucaine (6), amoxecaine (1), aptocaine (21), articaine (47) (previously carticaine (27)), benzocaine (42), betoxycaine (13), bucricaine (49), bumecaine (25), bupivacaine (17), butacaine (4), butanilicaine (16), chloroprocaine (6), cinchocaine (1), clibucaine (14), clodacaine (13), clormecaine (17), cyclomethycaine (6), dexivacaine (20), diamocaine (22), edronocaine (84), elucaine (29), etidocaine (29), fexicaine (25), fomocaine (18), hexylcaine (4), hydroxyprocaine (1), hydroxytetracaine (1), ipravacaine (85), ketocaine (15), leucinocaine (17), levobupivacaine (74), lidocaine (1), lotucaine (27), mepivacaine (11), meprylcaine (4), myrtecaine (15), octacaine (14), oxetacaine (13), oxybuprocaine (8), parethoxycaine (1), paridocaine (8), phenacaine (4), pinolcaine (32), piperocaine (1), piridocaine (1), pramocaine (4), pribecaine (32), prilocaine (14), procaine (10), propanocaine (6), propipocaine (16), propoxycaine (4) proxymetacaine (6), pyrrocaine (13), quatacaine (18), quinisocaine (4), risocaine (26), rodocaine (27), ropivacaine (50), tetracaine (4), tolycaine (16), trapencaine (56), trimecaine (11), vadocaine (57)

(c)

amolanone (6), benzyl alcohol (1), cryofluorane (6), diperodon (1), dyclonine (6), midamaline (6)

BAN

-cain- (x)

Class I antiarrhythmics, procainamide and lidocaine derivatives

H.2.0.0

(BAN: antifibrillants with local anaesthetic activity)

(a)

acecainide (39), asocainol (47), barucainide (52), bucainide (35), carcainium chloride (36), carocainide (46), droxicainide (47), encainide (40), epicainide (40), erocainide (50), flecainide (37), guafecainol (38), indecainide (48) (originally ricainide (47)), itrocainide (54), ketocainol (32), lorcainide (38), milacainide (77), modecainide (63), murocainide (46), nicainoprol (46), nofecainide (44), pilsicainide (62), pincainide (49), procainamide (1), quinacainol (50), recainam (54), solpecainol (55), stirocainide (47), suricainide (55), tocainide (36), transcainide (51), (verocainine (42) - replaced by tiapamil in List 43), zocainone (41)

USAN

calci

Vitamin D analogues/derivatives

N.8.0.0

(a)

alfacalcidol (40), calcifediol (26), calcipotriol (61), calcitriol (39), colecalciferol (13), doxercalciferol (82), ecalcidene (85), ergocalciferol (13), falecalcitriol (74), inecalcitol (87), lexacalcitol (71), maxacalcitol (75), paricalcitol (78), secalciferol (62), seocalcitol (78), tacalcitol (65)

(b)

calcitonin (31) (polypeptide)

(c)

dihydrotachysterol (1)

USAN

-carbef

antibiotics, carbacepham derivatives

S.6.1.0

(a)

loracarbef (60)

-carnil

see -azenil

BAN, USAN

cef- (x)

antibiotics, cefalosporanic acid derivatives

S.6.1.0

(USAN: cephalosporins)

(a)

cefacetrile (25), cefaclor (36), cefadroxil (33), cefalexin (18), cefaloglycin (16), cefalonium (16), cefaloram (16), cefaloridine (15), cefalotin (14), cefamandole (30), cefaparole (33), cefapirin (23), cefatrizine (34), cefazaflur (36), cefazedone (36), cefazolin (25), cefbuperazone (48), cefcanel (59), cefcanel daloxate (59), cefcapene (68), cefclidine (64), cefdaloxime (64), cefdinir (61), cefditoren (66), cefedrolor (53), cefempidone (58), cefepime (57), cefetamet (49), cefetecol (64), cefetrizole (44), cefivitril (52), cefixime (53), cefizopran (66), cefluprenam (71), cefmatilen (81), cefmenoxime (44), cefmepidium chloride (57), cefmetazole (39), cefminox (53), cefodizime (44), cefonicid (42), cefoperazone (42), ceforanide (39), cefoselis (71), cefotaxime (40), cefotetan (48), cefotiam (40), cefoxazole (34), cefoxitin (29), cefozopran (66), cefpimizole (50), cefpiramide (47), cefpirome (50), cefpodoxime (58), cefprozil (60), cefquinome (59), cefradine (26), cefrotil (34), cefroxadine (42), cefsulodin (38), cefsumide (38), ceftazidime (44), cefteram (55), ceftezole (34), ceftibuten (60), ceftiofur (53), ceftiolene (49), ceftioxide (43), ceftizoxime (42), ceftizoxime alaproxil (77), ceftriaxone (44), cefuracetime (45), cefuroxime (34), cefuzonam (55)

TRS 581

-oxef

antibiotics, oxacefalosporanic acid derivatives

S.6.1.0

(USAN: antibiotic oxacefalosporanic acid derivatives)

(a)

flomoxef (55), latamoxef (46)

cell- or

cellulose derivatives

cel-

[cel- in spanish]

U.4.0.0

(a)

celucloral (40)

(c)

celiprolol (35)

cell-ate

cellulose ester derivatives for substances containing acidic residues

U.4.0.0

[cel-ato in spanish]

(a)

cellaburate (23), cellacefate (18)

-cellose

cellulose ether derivatives

U.4.0.0

[-elosa in spanish]

(a)

-

(c)

carmellose (45), croscarmellose (48), ethylcellulose (80), hyetellose (80), hymetellose (80), hyprolose (80), hypromellose (18), methylcellulose (4)

USAN

-cic

hepatoprotective substances with a carboxylic acid group

J.1.2.0

(USAN: hepatoprotectives (timonacic group))

(a)

limazocic (69), tidiacic (33), timonacic (33), (tiofacic (45) replaced by stepronin (46))

(b)

bisorcic (34) (psychostimulant)

(c)

stepronin (46)

USAN

-cidin

naturally occurring antibiotics (undefined group) (14th Report, 1964)

S.6.0.0

(USAN: natural antibiotics (undefined group))

(a)

candicidin (17), gramicidin (1), gramicidin S (26), methocidin (6)

(b)

guancidine (18) (hypotensive)

BAN, USAN

-cillin (x)

antibiotics, 6-aminopenicillanic acid derivatives

S.6.1.0

(USAN: penicillins)

(a)

adicillin (14), almecillin (14), amantocillin (17), amoxicillin (27), ampicillin (13), apalcillin (39), aspoxicillin (50), azidocillin (19), azlocillin (36), bacampicillin (32), benethamine penicillin (1), benzathine benzylpenicillin (18), benzylpenicillin (53), carbenicillin (20), carfecillin (30), carindacillin (29), ciclacillin (22), clemizole penicillin (8), clometocillin (12), cloxacillin (13), dicloxacillin (16), epicillin (25), fenbenicillin (13), fibracillin (30), flucloxacillin (17), fomidacillin (55), fumoxicillin (47), furbucillin (31), fuzlocillin (47), hetacillin (16), isopropicillin (12), lenampicillin (50), levopropicillin (12), metampicillin (20), meticillin (12), mezlocillin (34), nafcillin (13), oxacillin (15), oxetacillin (33), penamecillin (16), pheneticillin (11), phenoxymethyl penicillin (6), phenyracillin (8), piperacillin (38), pirbenicillin (35), piridicillin (43), piroxicillin (49), pivampicillin (23), prazocillin (27), propicillin (13), quinacillin (14), rotamicillin (35), sarmoxicillin (41), sarpicillin (36), sulbenicillin (26), sultamicillin (48), suncillin (25), talampicillin (31), tameticillin (35), temocillin (46), ticarcillin (29), tifencillin (12), tobicillin (78)

(b)

xantocillin (12)

(c)

penimepicycline (16), penimocycline (22)

-cillide:

S.6.1.0

libecillide (32)

-cillinam:

S.6.1.0

bacmecillinam (38), mecillinam (32), pivmecillinam (32)

TRS 581

-cisteine

see -steine

USAN

-citabine

nucleoside antiviral or antineoplastic agents, cytarabine or azarabine derivatives

L.4.0.0

(a)

ancitabine (36), capecitabine (72), decitabine (61), enocitabine (46), fiacitabine (59), flurocitabine (38), galocitabine (65), gemcitabine (62), ibacitabine (57), tezacitabine (84), torcitabine (87), troxacitabine (81), zalcitabine (66)

(b)

cytarabine (14), azacitidine (40)

-clone

hypnotic tranquillizers

A.2.2.0

(a)

barbexaclone (16), eszopiclone (87), pagoclone (74), pazinaclone (70), suproclone (46), suriclone (43), suproclone (46), zopiclone (39)

(b)

gestaclone (23), pimeclone (20)

-cog

blood coagulation factors

I.2.0.0

(-)eptacog blood coagulation VII:

eptacog alfa (activated) (72)

(-)octocog blood factor VIII:

moroctocog alfa (72), octocog alfa (73)

(-)nonacog blood factor IX:

nonacog alfa (77)

related: drotrecogin alfa (85), tifacogin (78)

BAN, USAN

-conazole (x)

systemic anifungal agents, miconazole derivatives

S.4.0.0

(BAN: systemic antifungals of the miconazole group)

(USAN: systemic antifungals (miconazole type))

(a)

albaconazole (87), aliconazole (43), alteconazole (53), azaconazole (45), becliconazole (65), brolaconazole (58), butoconazole (40), cisconazole (59), croconazole (55), (cyproconazole (ISO)), democonazole (42), (diniconazole (ISO C₁₇H₁₇Cl₂N₃O)), doconazole (37), eberconazole (64), econazole (27), enilconazole (44), ((etaconazole (ISO)), fenticonazole (44), fluconazole (54), fosfluconazole (83), ((furconazole (ISO/TC 81 N 872 C₁₅H₁₄Cl₂F₃N₃O₂)), (hexaconazole (ISO C₁₄H₁₇Cl₂N₃O)), isoconazole (30), itraconazole (50), ketoconazole (43), lanoconazole (66), luliconazole (86), miconazole (22), neticonazole (63), omoconazole (45), orconazole (40), oxiconazole (42), parconazole (39), (penconazole, (ISO)), posaconazole (82), (propiconazole (ISO)), ravuconazole (83), saperconazole (59), sertaconazole (56), sulconazole (38), (tebuconazole (ISO C₁₆H₂₂CIN₃O)), terconazole (45) (originally triaconazole), tioconazole (40), (uniconazole (ISO C₁₅H₁₈ClN₃O)), valconazole (40), voriconazole (73), zinoconazole (50), zoficonazole (43)

(c)

bifonazole (44)

BAN, USAN

cort (x)

corticosteroids, except prednisolone derivatives

Q.3.0.0

(USAN: -cort-: cortisone derivatives)

(a)

amebucort (54), anecortave (80), butixocort (63), cicortonide (28), corticotropin (68), corticotropin-zinc hydroxide (68), cortisone (1), cortisuzol (30), cortivazol (23), cortodoxone (15), deflazacort (39) (previously azacort (38)), desoxycortone (4), fluazacort (30), fludrocortisone (6), fludroxycortide (12), fluocortin (31), formocortal (18), hydrocortamate (6), hydrocortisone (1), locicortolone dicibate (60), naflocort (50), nicocortonide (40), nivacortol (24), resocortol (74), tixocortol (38)

(b)

prednisolone derivatives: clocortolone (16), difluocortolone (18), fluocortolone (15), halocortolone (31)

(c)

aldosterone (6), algestone (22) (also progest. when used as algestone acetophenide), medrysone (16)

TRS 581

USAN

-crinat

diuretics, etacrynic acid derivatives

N.1.2.2

(USAN: diuretics (ethacrynic acid derivatives))

(a)

brocrinat (51), sulicrinat (52)

(c)

etacrynic acid (14), furacrinic acid (29), indacrinone (51), tienilic acid (25)

USAN

-crine (d)

acridine derivatives

(a)

antineoplastics: amsacrine (44), nitracrine (35)

anthelminthics; antimalarials: floxacrine (34), mepacrine (4)

antidepressants: dimetacrine (19), monometacrine (19)

antiparkinsonian: botiacrine (38)

acetylcholinesterase inhibitors: ipidacrine (73), suronacrine (61), tacrine (8), velnacrine (61)

(c)

acridorex (21), acriflavinium chloride (1), acrisorcin (13), aminoacridine (1), ethacridine (1), proflavine (1)

USAN

-cromil

antiallergics, cromoglicic acid derivatives

K.0.0.0

(USAN: antiallergics (cromoglicic acid type))

(a)

ambicromil (48) (replacement of probicromil (46)), isocromil (39), minocromil (50), nedocromil (50), proxicromil (39), terbucromil (38), texacromil (58)

(c)

cromitrile (46), cromoglicate lisetil (72), cromoglicic acid (18)

-curium

see -ium

BAN, USAN

-cycline (d)

antibiotics, tetracycline derivatives

S.6.3.0

(BAN: antibiotics of the tetracycline group)

(USAN: antibiotics tetracycline derivatives)

(a)

amicycline (14), apicycline (17), cetocycline (39), chlortetracycline (4), clomocycline (16), colimecycline (33), demeclocycline (25), demecycline (14), doxycycline (16), etamocycline (18), guamecycline (22), lymecycline (14), meclocycline (14), meglucycline (22), metacycline (12), minocycline (14), nitrocycline (14), oxytetracycline (1), pecocycline (15), penimepicycline (16), penimocycline (22), pipacycline (12), rolitetracycline (11), sancycline (15), tetracycline (4), tigecycline (86)

related: carubicin (40), daunorubicin (20), detorubicin (41), doxorubicin (25), zorubicin (39)

TRS 581

USAN

-dan

cardiac stimulants, pimobendan derivatives

H.1.0.0

(a)

adibendan (57), bemorodan (61), imazodan (55), indolidan (57), levosimendan (68), meribendan (62), pimobendan (46), prinoxodan (64), senazodan (85), simendan (66)

(b)

nitrodan (15), tyromedan (15)

USAN

-dapsone

antimycobacterials, diaminodiphenylsulfone derivatives (14th Report, 1964)

S.5.2.0

(USAN: antimycobacterial diaminodiphenylsulfone derivatives)

(a)

acedapsone (22), amidapsone (28), dapsone (23)

-dermin

see -ermin

USAN

-dil

vasodilators (18th Report, 1968)

F.2.0.0

F.2.1./2.0

(USAN: -dil; dil-; or -dil-: vasodilators (undefined group))

F.2.0.0

(a)

alprostadil (39), aviptadil (78), belfosdil (61), benfurodil hemisuccinate (16), biclodil (52), buflomedil (33), burodiline (26), carprazidil (45), cetiedil (27), cinepaxadil (50), dopropidil (59), eliprodil (66), fenoxedil (27), flosatidil (64), fostedil (51), fronepidil (59), ifenprodil (27), levosemotiadil (72), manozodil (47), mefenidil (48), minoxidil (25), naftopidil (52), naminidil (87), nesapidil (52), perfomedil (60), pinacidil (46), piribedil (23), pitenodil (37), podilfen (22), stevaladil (34), suloctidil (30), tipropidil (44), urapidil (27), viquidil (25)

(c)

dilmefone (33)

F.2.1.0

(a)

coronary vasodilators: bepridil (30), bumepidil (44), ecipramidil (40), fendiline (24), fenetradil (30), floredil (28), hexadiline (13), ipramidil (51), mepramidil (27), metrifudil (23), nicorandil (44), pirozadil (33), pretiadil (27), razi-nodil (38), semotiadil (64), sinitrodil (74), terodiline (16), tixadil (18), trapidil (29)

(c)

dilazep (22), diltiazem (30)

-dilol

carvedilol (50), dioxadilol (53), dramedilol (57), flavodilol (48), mindodilol (52), nipradilol (50) (previously nipradolol), oberadilol (77), parodilol (57), prizidilol (44), tribendilol (54)

(b)

diloxanide (8) (amebicide), methdilazine (10) (antihistaminic), phenobutiodil (6) (contrast medium), prodilidine (12) (analgesic)

-pendyl

cloxypendyl (15), isothipendyl (6), oxypendyl (13), prothipendyl (6)

-dyl

bisacodyl (13) (lax.), bunamiodyl (10), iofendylate (12), trihexyphenidyl (1) (antiparksonian)

TRS 581

BAN, USAN

-dipine (x)

calcium channel blockers, nifedipine derivatives

F.2.1.0

(BAN: calcium ion channel antagonists)

(USAN: phenylpyridine vasodilators (nifedipine type))

(a)

amlodipine (53), aranidipine (69), azelnidipine (69), barnidipine (64), benidipine (58), cilnidipine (66), clevidipine (75), cronidipine (61), darodipine (51) (replaces dazodipine (49)), efonidipine (66), elgodipine (61), felodipine (44), flordipine (48), furnidipine (67), iganidipine (70), isradipine (55), lacidipine (57), lemildipine (69), lercanidipine (69) (previously masnidipine), levniguldipine (67), manidipine (59), mesudipine (40), nicardipine (42), nifedipine (27), niguldipine (60), niludipine (38), nilvadipine (52), nimodipine (40), nisoldipine (42), nitrendipine (42), olradipine (69), oxodipine (52), palonidipine (64), pranidipine (66), riodipine (51), sagandipine (64), sornidipine (58), teludipine (64) (previously taludipine (61))

(b)

budipine (36) (central stimulant, antidepressant and antiparkinsonian), prodipine (29) (central stimulant antiparkinsonian)

-dismase

enzymes with superoxide dismutase activity, see -ase item V

-dopa

dopamine receptor agonists, dopamine derivatives, used as antiparkinsonism/prolactin inhibitors

E.1.1.0

(a)

carbidopa (37), ciladopa (52), dopamantine (31), droxidopa (57), etilevodopa (80), fluorodopa (¹⁸F) (64), levodopa (21), melevodopa (83)

-opamine

dopaminergic agents dopamine derivatives used as cardiac stimulant/antihypertensives/diuretics

(a)

butopamine (43), cliropamine (59), denopamine (50), dopamine (18), fosopamine (69), ibopamine (43), octopamine (32), oxidopamine (37) (glaucoma), ractopamine (54) (1 of 4 isomers of butopamine)

(b)

tiopropamine (36) (gastric and duodenal ulcers), tolpropamine (13) (antihistaminic)

(c)

dobutamine (29), docarpamine (59), dopexamine (50), fenoldopam (53), levdobutamine (65), methyldopa (12) (alpha-2 adrenoreceptor agonist, cardiotonic), zelandopam (84)

USAN

-dralazine

antihypertensives, hydrazinephthalazine derivatives

H.3.0.0

(USAN: antihypertensives (hydrazine-phthalazines))

(a)

budralazine (33), cadralazine (41), dihydralazine (4), endralazine (39), hydralazine (1), mopidralazine (52), oxdralazine (38), picodralazine (18), pildralazine (48), todralazine (26)

-drine

sympathomimetics (16th Report, 1966)

E.4.0.0

(a)

alifedrine (49), butidrine (16), cafedrine (14), cinnamedrine (19), corbadrine (1), dioxethedrin (6), dioxifedrine (41), etafedrine (14), meluadrine (78), methoxyphedrine (6), midodrine (27), norbudrine (17), oxyfedrine (16), pholedrine (1), pseudoephedrine (11), racephedrine (66), ritodrine (22), theophylline ephedrine (14), tinofedrine (32), trecadrine (53)

not phenethylamine derivatives: levopropylhexedrine (37), octodrine (19), propylhexedrine (6)

(b)

bufenadrine (13) (antiemetic) related chemically, chlormerodrin (4) (diuretic), chlormerodrin (197 Hg) (24), dieldrin (10) (insecticide), orphenadrine (8) (spasmolytic)

TRS 581

-frine

sympathomimetic, phenethyl derivatives

E.4.0.0

(a)

amidefrine mesilate (15), berefrine (68), ciclafrine (33), dimetofrine (27), dipivefrine (39), epinephrine (16), etilefrine (18), etilefrine pivalate (50), gepefrine (38), norepinephrine (45), norfenefrine (16), oxilofrine (62), phenylephrine (1), pivenfrine (42), racepinefrine (41)

USAN

-dronic acid

calcium metabolism regulator, pharmaceutical aid

N.8.0.0

U.4.0.0

(USAN: -dronate: calcium metabolism regulators)

(a)

alendronic acid (61), butedronic acid (59), clodronic acid (37), etidronic acid (22), ibandronic acid (71), incadronic acid (70), lidadronic acid (84), medronic acid (39), minodronic acid (78), neridronic acid (61), olpadronic acid (71), oxidronic acid (42), pamidronic acid (59), piridronic acid (58), risedronic acid (62), tiludronic acid (60), zoledronic acid (71)

USAN

-ectin

antiparasitics, ivermectin derivatives

S.3.0.0

(a)

abamectin (53), dimadectin (73), doramectin (63), eprinomectin (73), fuladectin (71), ivermectin (44), moxidectin (61), nemadectin (60), selamectin (81)

USAN

-entan

endothelin receptor antagonists

F.2.0.0

(a)

ambrisentan (85), atrasentan (83), bosentan (70), darusentan (82), edonentan (86), enrasentan (80), fandosentan (87), feloprentan (85), sitaxentan (83), tezosentan (81)

USAN

erg

ergot alkaloid derivatives

F.4.0.0

C.7.0.0

(USAN: -erg-: ergot alkaloid derivatives)

(a)

acetergamine (18), amesergide (67), brazergoline (37), bromerguride (51), cabergoline (54), cianergoline (47), delergotrile (42), dihydroergotamine (16), disulergine (45), dosergoside (54), ergometrine (4), ergotamine (4), etisulergine (47), lergotrile (32), lysergide (8), mergocriptine (54), mesulergine (47), metergoline (18), metergotamine (29), methylergometrine (1), methysergide (11), nicergoline (26), pergolide (41), propisergide (35), proterguride (50), romergoline (66), sergolexole (60), terguride (50), tiomergine (42), voxergolide (61)

(b)

ergocalciferol (13)

USAN

-eridine

analgesics, pethidine derivatives (14th Report, 1964)

A.4.1.0

(USAN: analgesics (meperidine group))

(a)

anileridine (5), carperidine (11), etoxeridine (6), morpheridine (6), oxpheneridine (5), pheneridine (5), phenoperidine (11), properidine (5), sameridine (68), trimeperidine (6)

(b)

diaveridine (18) (coccidiostat.), eseridine (53), nexeridine (34) (somewhat related)

(c)

benzethidine (9), butoxylate (14), diphenoxylate (10), fetoxilate (21), furethidine (9), hydroxypethidine (5), pethidine (4), piminodine (9)

USAN

-ermin

growth factors

U.0.0.0

(USAN: growth factors)

-bermin

vascular endothelial growth factors

(a)

telbermin (85)

-dermin

epidermal growth factors

(a)

murodermin (63)

-fermin

fibrinoblast growth factors

(a)

ersofermin (66), palifermin (86), repifermin (82), trafermin (74)

-filermin

leukemia-inhibiting factor

(a)

emfilermin (82)

-nermin

tumour necrosis factor

(a)

plusonermin (73), sonermin (68), tasonermin (76)

-plermin

platelet-derived growth factor

(a)

becaplermin (74)

-sermin

insulin-like growth factors

(a)

mecasermin (66)

-termin

transforming growth factor

avotermin (77), cetermin (74), liatermin (81)

BAN, USAN

estr

estrogens

Q.2.1.0

(USAN: estr-; or -estr-: estrogens)

(a)

almestrone (24), benzestrol (1), broparestrol (8), cloxestradiol (12), dienestrol (1), diethylstilbestrol (4), epiestriol (12), epimestrol (22), (eptamestrol/etamestrol (49) deleted), estradiol (4), estradiol benzoate (4), estradiol undecylate (16), estradiol valerate (35), estramustine (24), estrapronicate (34), estrazinol (16), estriol succinate (14), estrofurate (25), estrone (4), ethinylestradiol (1), fenestrel (18), fosfestrol (15), fulvestrant (78), furostilbestrol (1), hexestrol (1), mestranol (12), methallenestril (6), methestrol (1), moxestrol (24), nilestriol (32), orestrate (17), polyestradiol phosphate (36), promestriene (31), quinestradol (15), quinestrol (14)

(b)

alfatradiol (84) (topical), allylestrenol (10) (progest.), ethylestrenol (13) (anabol.), lynestrenol (13) (progest.)

-gestr-:

edogestrone (22), levonorgestrel (30), megestrol (13), melengestrol (13), norgestrel (17), norgestrienone (18), pentagestrone (14), quingestrone (13)

(c)

chlorotrianisene (6), clomifene (12), enclomifene (33), zuclomifene (33) (antiestrogens)

TRS 581

-etanide

see -anide

-ethidine

see -eridine

-exine

mucolytic, bromhexine derivatives

K.0.0.0

(a)

adamexine (36), bromhexine (20), brovanexine (31), cistinexine (54), dembrexine (56), neltenexine (62), oxabrexine (40)

(b)

enefexine (54) (antidepressant), gamfexine (17) (antidepressant)

(c)

ambroxol (32) (dembrexol (50): replaced by dembrexine (56))

USAN

-fenamic acid

anti-inflammatory, anthranilic acid derivatives

-fenamate

"fenamic acid" derivatives

A.4.2.0

(a)

clofenamic acid (13), enfenamic acid (45), flufenamic acid (13), meclofenamic acid (17), mefenamic acid (13), tolfenamic acid (24) colfenamate (29), etofenamate (29), prefenamate (36), terofenamate (32), ufenamate (50)

(b)

clantifen (24), oxyfenamate (13)

phonetically close: clofenamide (13), diclofenamide (13) (N.1.1.0)

(c)

flutiazin (22)

USAN

-fenine

analgesics, glafenine derivatives (subgroup of fenamic acid group)

phenine

A.4.3.0

(a)

antrafenine (35), floctafenine (24), florifenine (50), glafenine (15), nicafenine (40)

(b)

spasmolytic diphenylacetates: adiphenine (1), drofenine (26)

other: bufenine (8) (vasodil.), cinfenine (27) (antidepressant)

USAN

-fenin

diagnostic aids; (phenylcarbamoyl)methyl iminodiacetic acid derivatives

U.1.0.0

(a)

arclofenin (52), butilfenin (41), disofenin (43), etifenin (43), galtifenin (59), lidofenin (39), mebrofenin (47)

USAN

-fentanil

narcotic analgesics, fentanyl derivatives

A.4.1.0

(a)

alfentanil (43), brifentanil (62), carfentanil (39), fentanyl (14), lofentanil (43), mirfentanil (64), ocfentanil (61), remifentanil (67), sufentanil (36), trefentanil (67)

-fiban

fibrinogen receptor antagonists (glycoprotein IIb/IIIa receptor antagnists)

I.2.0.0

carafiban (78), elarofiban (83), fradafiban (72), gantofiban (80), lamifiban (72), lefradafiban (75), lotrafiban (78), orbofiban (75), roxifiban (77), sibrafiban (77), tirofiban (73), xemilofiban (74)

BAN, USAN

-fibrate (x)

clofibrate derivatives

H.4.0.0

(BAN: substances of the clofibrate group)

(USAN: clofibrate type compounds)

(a)

bezafibrate (35), biclofibrate (28), binifibrate (44), ciprofibrate (36), clinofibrate (39), dulofibrate (43), etofibrate (31), fenirofibrate (49), fenofibrate (35), lifibrate (30), nicofibrate (31), picafibrate (35), ponfibrate (37), ronifibrate (55), salafibrate (41), serfibrate (34), simfibrate (22), sitofibrate (32), tiafibrate (33), timofibrate (40), tocofibrate (33), urefibrate (37), xantifibrate (31)

clofibric acid (20), clofibrate (13), aluminium clofibrate (31), calcium clofibrate (34), cinnarizine clofibrate (38), etofylline clofibrate (38), magnesium clofibrate (31)

clofibride (28), plafibride (39)

related: beclobrate (35), eniclobrate (39), gemfibrozil (34), halofenate (20), lifibrol (62), metibride (53), terbufibrol (35), tibric acid (33), (fibrafylline (43) deleted)

(b)

bromebric acid (25) (prophylaxis of migraine), fibracillin (30) (antibiotic)

(c)

nafenopin (24), treloxinate (25)

TRS 581

-flapon

5-lipoxygenase-activating protein (FLAP) inhibitor

K.0.0.0

J.0.0.0

quiflapon (72)

-flurane

halogenated compounds used as general inhalation anaesthetics

A.1.1.0

(a)

aliflurane (36), cryofluorane (6), desflurane (62), enflurane (25), isoflurane (28), methoxyflurane (11), norflurane (20), roflurane (12), sevoflurane (25), teflurane (12)

(b)

apaflurane (73)

(c)

halothane (6)

TRS 581

perfl(u)-

perfluorinated compounds used as blood substitutes and/or diagnostic agents

(a)

perflexane (82), perfluamine (45), perflubrodec (87), perflubron (66), perflunafene (45), perflutren (82)

USAN

-formin (d)

antihyperglycaemics, phenformin derivatives

M.5.0.0

(USAN: oral hypoglycemics (phenformin type))

(a)

benfosformin (29), buformin (17), etoformin (34), metformin (21), phenformin (10), tiformin (22)

TRS 581

-fos

insecticides, anthelminthics, pesticides etc., phosphorous derivatives

(-vos)

S.3.1.0

Y.0.0.0

1.

organophosphorous derivatives:

(a)

vet. insecticides:

quintiofos (25)

(b)

toldimfos (23) (vet. phosphorous source)

(c)

vet. insecticides and anthelminthics:

metrifonate (16)

anthelmintic: butonate (30)

2.

phosphates:

(a)

vet. insecticides:

clofenvinfos (23)

vet. anthelminthics:

bromofenofos (43), dichlorvos (28), naftalofos (16)

anthelminthics:

vincofos (28)

(b)

triclofos (13) (hypnotic, sedative)

(c)

vet. anthelminthics:

fospirate (21), haloxon (16)

3.

phosphorothioates:

vet. insecticides:

(a)

bromofos (25), coumafos (16), fenclofos (23), temefos (31)

(c)

dimpylate (16), phoxim (20) (vet. insecticide and anthelmintic), pyrimitate (16)

4.

phosphorodithioates:

(a)

benoxafos (22) (vet. pesticide)

(c)

carbofenotion (23) (vet. insecticide), dioxation (16) (vet. insecticide), (malathion (46) (deleted!))

5.

phosphoramidates

crufomate (16), uredofos (37)

anthelminthic:

imcarbofos (44)

-fos- or fos-

various pharmacological categories belonging to fos (other than those above):

-fos-

alafosfalin (41), amifostine (44), belfosdil (61), benfosformin (29), butafosfan (38), cifostodine (50), creatinolfosfate (20), dexfosfoserine (68), ferpifosate sodium (69), fosmenic acid (49), fosopamine (69), fosquidone (64), furifosmin (70), monophosphothiamine (8), sodium picofosfate (37), sparfosic acid (46), technetium (^99mTc), tetrofosmin (66), trifosmin (74)

-fosfamide alkylating agents of the cyclophosphamide group

cyclophosphamide (10), defosfamide (12), glufosfamide (77), ifosfamide (23), mafosfamide (51), perfosfamide (66), sufosfamide (36), trofosfamide (23)

-fosine cytostatic

edelfosine (59), fostriecin (55), ilmofosine (56), miltefosine (61), perifosine (78)

fos-

fosarilate (53), fosazepam (27), foscarnet sodium (42), foscolic acid (12), fosenazide (46), fosfestrol (15), fosfocreatinine (50), fosfomycin (25), fosfonet sodium (35), fosfosal (37), fosfructose (81), fosmidomycin (46), fostedil (51)

-fradil

alcium channel blockers acting as vasodilators

F.2.1.0

mibefradil (72)

-frine

see -drine

USAN

-fungin

antifungal antibiotics (18th Report, 1968)

S.6.0.0

(USAN: antifungal antibiotics (undefined group))

S.4.3.0

(a)

abafungin (74), anidulafungin (81), basifungin (72), caspofungin (80), cilofungin (60), fusafungine (15), kalafungin (20), micafungin (84), nifungin (24), oxifungin (40), sinefungin (39), triafungin (40)

TRS 581

USAN

-fylline

N-methylated xanthine derivatives

B.1.0.0

(a)

acefylline clofibrol (44), acefylline piperazine (14), albifylline (66), aminophylline (4), apaxifylline (71), arofylline (75), bamifylline (15), cipamfylline (71), denbufylline (55), dimabefylline (19), diniprofylline (18), diprophylline (1), doxofylline (47), enprofylline (44), etamiphylline (6), etofylline (14), etofylline clofibrate (38), fibrafylline (43) (deleted), flufylline (48), fluprofylline (50), furafylline (48), guaifylline (16), isbufylline (62), laprafylline (60), lisofylline (72), lomifylline (37), mercurophylline (1), metescufylline (15), mexafylline (48), midaxifylline (79), naxifylline (86), nestifylline (64), pentifylline (29), pentoxifylline (29), perbufylline (58), pimefylline (21), propentofylline (46), proxyphylline (10), pyridofylline (14), spirofylline (58), stacofylline (73), tazifylline (52), theophylline ephedrine (14), torbafylline (56), triclofylline (19), verofylline (43), visnafylline (24), choline theophyllinate (8), fenetylline (16)

(c)

cafedrine (14), dimenhydrinate (1), dimethazan (8), meralluride (1), mercumatilin sodium (4), piprinhydrinate (8), promethazine teoclate (10), protheobromine (14), theodrenaline (14), xantifibrate (31), xantinol nicotinate (16)

radicals and groups: teprosilate (29)

TRS 581

USAN

gab

gabamimetic agents

E.0.0.0

(a)

fengabine (53), gabapentin (46), gaboxadol (48) (used as analgesic), pivagabine (66), pregabalin (78), progabide (43) (used as antiepileptic), retigabine (76), tiagabine (63), tolgabide (53), vigabatrin (52) (anticonvulsants)

(b)

gabexate (35) (proteolytic)

USAN

gado-

diagnostic agents, gadolinium derivatives

U.0.0.0

(a)

gadobenic acid (64), gadobutrol (66), gadocoletic acid (85), gadodiamide (63), gadomelitol (85), gadopenamide (60), gadopentetic acid (50), gadoteric acid (59), gadoversetamide (71), gadoxetic acid (71)

USAN

-gatran

thrombin inhibitor, antithrombotic agent

I.2.0.0

(a)

dabigatran (83), dabigatran etexilate (87), efegatran (71), inogatran (72), melagatran (74), napsagatran (72), ximelagatran (84)

(c)

argatroban (57)

BAN, USAN

gest (x)

steroids, progestogens

Q.2.2.0

(USAN: -gest-: progestins)

(a)

altrenogest (46), anagestone (16), cingestol (20), clogestone (21), clomegestone (20), demegestone (24), desogestrel (38), dexnorgestrel (30), dienogest (49), dydrogesterone (12), edogestrone (22), etonogestrel (65), flugestone (16), gestaclone (23), gestadienol (22), gestodene (37), gestonorone caproate (16), gestrinone (39), haloprogesterone (11), hydroxyprogesterone (8), levonorgestrel (33) (previously dexnorgestrel), medrogestone (15), medroxyprogesterone (10), medoxyprogesterone (10), medrogestone (15), megestrol (13), melengestrol (13), metogest (33), norelgestromin (83), norgesterone (14), norgestimate (35), norgestomet (32), norgestrel (17), norgestrienone (18), oxogestone (19), pentagestrone (14), progesterone (4), proligestone (28), promegestone (38), quingestanol (15), quingestrone (13), tigestol (20), tosagestin (86), trengestone (22), trimegestone (66)

(b)

algestone (22) (glucorticoid)

(c)

allylestrenol (10), chlormadinone (12), cismadinone (12), delmadinone (23), dimethisterone (8), ethisterone (4), ethynerone (17), etynodiol (13), hydromadinone (12), lynestrenol (13), metynodiol (27), norethisterone (6), noretynodrel (13), norvinisterone (10)

clometerone (15) (antiestrogen), dimepregnen (24) (antiestrogen)

USAN

-giline

MAO-inhibitors type B

C.3.1.0

(a)

clorgiline (23), mofegiline (69), pargiline (13), rasagiline (70), selegiline (39)

-gillin

antibiotics produced by Aspergillus strains (16th Report, 1966)

S.6.0.0

(a)

fumagillin (1), mitogillin (17)

(c)

mitosper (24), nifungin (24)

BAN, USAN

gli (x)

antihyperglycaemics, sulfonamide derivatives

(previously gly-)

M.5.2./3.0

(BAN: sulphonamide hypoglycaemics)

(USAN: gli-: oral hypoglycemics (glipizide type))

(a)

gliamilide (33), glibenclamide (18), glibornuride (22), glibutimine (31), glicaramide (28), glicetanile (37), gliclazide (25), (deleted: glidanile (23)), glicondamide (44), glidazamide (24), gliflumide (33), glimepiride (53), glipalamide (62), (glipentide (27) replaced by glisentide (58)), glipizide (27), gliquidone (28), glisamuride (45), glisentide (58) (previously glipentide), glisindamide (43), glisolamide (43), glisoxepide (24), glybuthiazol (8), glybuzole (15), glyclopyramide (17), glycyclamide (12), glyhexamide (15), glymidine sodium (15), glyoctamide (14), glyparamide (USAN only), glypinamide (13), glyprothiazol (8), glysobuzole (12)

(b)

glycerol (4), glycobiarsol (1), glycopyrronium bromide (12)

(c)

1.: acetohexamide (12), butadiazamide (10), chlorpropamide (8), heptolamide (12), metahexamide (10), thiohexamide (12), tolazamide (12), tolbutamide (6), tolpentamide (12), tolpyrramide (13)

2. other than sulfonamide derivatives: balaglitazone (84), camiglibose (67), ciglitazone (50), darglitazone (69), deriglidole (66), emiglitate (55), englitazone (64), farglitazar (84), ingliforib (85), isaglidole (61), linogliride (48), meglitinide (34), midaglizole (57), miglitol (55), mitiglinide (78), naglivan (65), nateglinide (77), netoglitazone (85), pioglitazone (60), pirogliride (40), ragaglitazar (85), reglitazar (84), repaglinide (65), rivoglitazone (84), rosiglitazone (78), tesaglitazar (85), tibeglisene (64), troglitazone (68), voglibose (65)

3. peptide: seglitide (57)

TRS 581

-golide

dopamine receptor agonists, ergoline derivatives

E.1.1.0

(a)

adrogolide (82), naxagolide (60), pergolide (41), quinagolide (62), voxergolide (61)

(c)

rotigotine (83)

-grastim

see -stim

USAN

-grel-

platelet aggregation inhibitors

-grel

I.2.1.0

(USAN: platelet antiaggregants (undefined group))

(a)

anagrelide (42), camonagrel (61), cangrelor (82), clopidogrel (57), dazmegrel (51), furegrelate (53), isbogrel (59), itazigrel (56), midazogrel (53), nafagrel (64), nicogrelate (48), oxagrelate (47), ozagrel (55), pamicogrel (70), pirmagrel (53), ridogrel (59), rolafagrel (65), samixogrel (72), sarpogrelate (63), satigrel (67), sunagrel (52), terbogrel (75), trifenagrel (53)

USAN

guan-

antihypertensives, guanidine derivatives

H.3.0.0

(USAN: anti-hypertensive substances (guanidine type))

(a)

guanabenz (26), guanacline (16), guanadrel (20), guanazodine (27), guancidine (18), guanclofine (36), guanethidine (11), guanfacine (35), guanisoquine (15), guanoclor (15), guanoctine (16), guanoxan (15), guanoxabenz (31), guanoxyfen (16), guabenxan (32)

(c)

guabenxan (32)

-ibine

see -ribine

USAN

-icam

anti-inflammatory, isoxicam derivatives

A.4.2.0

(USAN: anti-inflammatory agents (isoxicam group))

(a)

ampiroxicam (56), droxicam (52), enolicam (45), isoxicam (30), lornoxicam (59), meloxicam (52), piroxicam (32), sudoxicam (27), tenoxicam (44), tesicam (25)

USAN

-ifene

antiestrogens, clomifene and tamoxifen derivatives

(Q.2.1.0 L.6.0.0)

(a)

acolbifene (86), arzoxifene (80), bazedoxifene (86), clomifene (12), droloxifene (53), enclomifene (33), idoxifene (68), lasofoxifene (81), levormeloxifene (73), miproxifene (74), nitromifene (33), ormeloxifene (69), ospemifene (85), panomifene (58), pipendoxifene (84), raloxifene (54), tamoxifen (28), tesmilifene (81), toremifene (53), trioxifene (41), zindoxifene (54), zuclomifene (33), clomifenoxide (54)

(b)

dextropropoxyphene (7), levopropoxyphene (7), suloxifen (30) (bronchodilator)

(c)

nafoxidine (16)

-igetide

see -tide

USAN

-ilide

class III antiarrhythmics, sematilide derivatives

H.2.0.0

(a)

ambasilide (59), artilide (67), azimilide (72), dofetilide (65), ersentilide (72), ibutilide (63), ipazilide (62), risotilide (62), sematilide (58), trecetilide (79)

(b)

bromacrylide (13), ftaxilide (32), gliamilide (33)

USAN

imex (d)

immunostimulants

S.7.0.0

(a)

azimexon (40), forfenimex (55), imexon (37), roquinimex (53), ubenimex (56)

USAN

-imod

immunomodulators, both stimulant/suppressive and stimulant

S.7.0.0

(a)

atiprimod (75), cridanimod (83), defoslimod (79), esonarimod (79), glaspimod (74), iguratimod (86), imiquimod (66), ivarimod (60), laquinimod (85), pidotimod (63), resiquimod (82), susalimod (73), tiprotimod (57)

USAN

-imus

immunosuppressants (other than antineoplastics)

S.7.0.0

(a)

abetimus (81), anisperimus (82), everolimus (82), gusperimus (68), iguratimod (86), laflunimus (70), laquinimod (85), napirimus (60), pimecrolimus (81), sirolimus (69), tacrolimus (66), tresperimus (75)

-ine (d)

alkaloids and organic bases

(a)

1120 (24.04%) INNs ending in -ine in Lists 1-48 of Proposed INNs

BAN, USAN

io- (x)

iodine-containing contrast media

U.1.1.0

(a)

iobenzamic acid (14), iobitridol (68), iobutoic acid (20), iocarmic acid (22), iocetamic acid (18), iocanlidic acid (77), iodamide (15), iodecimol (51), iodetryl (1), iodixanol (53), iodophthalein sodium (1), iodoxamic acid (26), iofendylate (12), iofratol (67), ioglicic acid (33), ioglucol (41), ioglucomide (41), ioglunide (40), ioglycamic acid (15), iohexol (43), iolidonic acid (26), iolixanic acid (26), iomeglamic acid (26), iomeprol (54), iomorinic acid (37), iopamidol (40), iopanoic acid (1), iopentol (52), iophenoic acid (4), ioprocemic acid (39), iopromide (44), iopronic acid (28), iopydol (14), iopydone (14), iosarcol (54), iosefamic acid (14), ioseric acid (33), iosimide (50), iosulamide (39), iosumetic acid (33), iotalamic acid (13), iotasul (43), iotetric acid (37), iotranic acid (28), iotriside (60), iotrizoic acid (22), iotrolan (51), iotroxic acid (32), ioversol (56), ioxabrolic acid (53), ioxaglic acid (37), ioxilan (59), ioxitalamic acid (22), ioxotrizoic acid (33), iozomic acid (24)

(c)

adipiodone (4), bunamiodyl (10), dimethiodal sodium (1), diodone (1), ethyl cartrizoate (12), methiodal sodium (1), metrizamide (26), pheniodol sodium (1), phenobutiodil (6), propyl docetrizoate (10), propyliodone (1), sodium acetrizoate (4), sodium amidotrizoate (4), sodium diprotrizoate (6), sodium metrizoate (13), sodium tyropanoate (12)

TRS 581

iod-)

iodine-containing compounds other than contrast media

-io-)

io(d)-/-io-

iodine-containing radiopharmaceuticals

(a)

ethiodized oil (¹³¹I) (24), iobenguane (¹³¹I) (57), iodinated (¹²⁵I) human serum albumin (24), iodinated (¹³¹I) human serum albumin (24), iodocetylic acid (¹²³I) (47), iodocholesterol (¹³¹I) (39), iofetamine (¹²³I) (51), iolopride (¹²³I) (73), iomazenil (¹²³I) (66), iometin (¹²⁵I), iometin (¹³¹I) (24), sodium iodide (¹²⁵I) (24), sodium iodide (¹³¹I) (24), sodium iodohippurate (¹³¹I) (24), sodium iotalamate (¹²⁵I (24), sodium iotalamate (¹³¹I) (24)

(c)

fibrinogen (¹²⁵I), macrosalb (¹³¹I) (33), rose bengal (¹³¹I) sodium (24), tolpovidone (¹³¹I) (24)

USAN

-irudin

hirudin derivatives

I.2.1.0

bivalirudin (72), desirudin (70), lepirudin (73), pegmusirudin (77)

USAN

-isomide

antiarrhythmics, disopyramide derivatives

H.2.0.0

(a)

actisomide (60), bidisomide (63), pentisomide (59)

(c)

disopyramide (12)

BAN, USAN

-ium (x)

qarternary ammonium compounds

(USAN: -ium or onium)

USAN

E.3.0.0

neuromuscular blocking agents with a flexible structure

(a)

azamethonium bromide (1), decamethonium bromide (1), dicolinium iodide (25), dimecolinium iodide (14), fubrogonium iodide (18), hexamethonium bromide (1), mebezonium iodide (16), oxapropanium iodide (1), oxydipentonium chloride (1), pentamethonium bromide (1), pentolonium tartrate (4), prodeconium bromide (6), stilonium iodide (32), suxamethonium chloride (1), suxethonium chloride (1), tetrylammonium bromide (1), tiametonium iodide (15), trepirium iodide (25)

(c)

gallamine triethiodide (1)

E.3.0.0

neuromuscular blocking agents with rigid structure

(USAN: -curium, also curonium; neuromuscular blocking agents; quaternary ammonium derivatives)

(a)

alcuronium chloride (17), atracurium besilate (42), candocuronium iodide (70), cisatracurium besilate (73), dacuronium bromide (21), dimethyltubocurarinium chloride (1), doxacurium chloride (58), fazadinium bromide (32), hexafluronium bromide (12), laudexium metilsulfate (4), mivacurium chloride (58), pancuronium bromide (19), pentacynium chloride (6), phenactropinium chloride (8), pipecuronium bromide (69), piprocurarium iodide (11), rapacuronium bromide (78), rocuronium bromide (66), stercuronium iodide (21), thiazinamium metilsulfate (37), trimethidinium methosulfate (8), truxicurium iodide (22), truxipicurium iodide (22), vecuronium bromide (46)

(c)

tubocurarine chloride (1)

E.1.0.0

cholinergic agents

(a)

aclatonium napadisilate (44), ambenonium chloride (6), benzpyrinium bromide (1), carpronium chloride (23), demecarium bromide (10), furtrethonium iodide (1)

(c)

acetylcholine chloride (4), charbacol (4), choline alfoscerate (29), choline chloride (4), choline gluconate (1), choline salicylate (15) (analgesic), choline theophyllinate (8) (smooth muscle relaxant), methacholine chloride (1), nitricholine perchlorate (6) (antihypertensive), distigmine bromide (16), ecothiopate iodide (6), neostigmine bromide (4), obidoxime chloride (16), pralidoxime iodide (10), pyridostigmine bromide (6)

E.2.0.0

anticholinergic agents

(a)

benzilonium bromide (13), benzopyrronium bromide (12), beperidium (57), bevonium metilsulfate (19), butropium bromide (30), ciclonium bromide (19), ciclotropium bromide (50), cimetropium bromide (51), clidinium bromide (6), cyclopyrronium bromide (12), dimetipirium bromide (37), diponium bromide (15), dotefonium bromide (24), droclidinium bromide (33), emepronium bromide (18), etipirium iodide (22), fenclexonium metilsulfate (20), fenpiverinium bromide (26), fentonium bromide (29), flutropium bromide (50), glycopyrronium bromide (12), heteronium bromide (14), hexasonium iodide (15), hexocyclium metilsulfate (6), hexopyrronium bromide (13), ipratropium bromide (31), methanthelinium bromide (1), methylbenactyzium bromide (34), metocinium iodide (26), nolinium bromide (37), otilonium bromide (38), oxapium iodide (26), oxitefonium bromide (18), oxitropium bromide (36), oxyphenonium bromide (1), oxypyrronium bromide (13), oxysonium iodide (15), pentapiperium metilsulfate (26), prifinium bromide (20), ritropirronium bromide (33), sintropium bromide (47), sultroponium (18), tematropium metilsulfate (64), tiemonium iodide (13), timepidium bromide (29), tiotropium bromide (67), tiquizium bromide (47), trantelinium bromide (24), trospium chloride (25), xenytropium bromide (15)

(c)

atropine methonitrate (4), buzepide metiodide (14), chlorisondamine chloride (6), diphemanil metilsulfate (4), homatropine methylbromide (1), isopropramide iodide (8), mepenzolate bromide (10), octatropine methylbromide (10), parapenzolate bromide (14), pipenzolate bromide (6), poldine metilsulfate (11), propantheline bromide (1), propyromazine bromide (12), tridihexethyl iodide (6), tropenziline bromide (11), thihexinol methylbromide (1), tricyclamol chloride (4)

S.2.3.0

surfactants used as antibacterials and antiseptics

(a)

acriflavinium chloride (1), amantanium bromide (39), benzalko-nium chloride (1), benzethonium chloride (1), benzododecinium chloride (1), benzoxonium chloride (36), cefalonium (16), cefmepidium chloride (57), cetalkonium chloride (15), cethexonium chloride (36), cetrimonium bromide (1), cetylpyridinium chloride (1), chlorphenoctium amsonate (8), deditonium bromide (15), denatonium benzoate (15), dequalinium chloride (8), disiquonium chloride (55), dodeclonium bromide (16), dofamium chloride (21), fludazonium chloride (33), furazolium chloride (15), halopenium chloride (10), hedaquinium chloride (8), lapirium chloride (27), lauralkonium chloride (62), laurcetium bromide (70), laurolinium acetate (12), mecetronium etilsulfate (51), metalkonium chloride (60), methylbenzethonium chloride (1), methylrosanilinium chloride (1), methylthioninium chloride (1), miripirium chloride (63), miristalkonium chloride (41), octafonium chloride (16), opratonium iodide (76), penoctonium bromide (20), pirralkonium bromide (19), polidronium chloride (67), polixetonium chloride (70), prolonium iodide (14), sanguinarium chloride (68), sepazonium chloride (34), tetradonium bromide (18), tibezonium iodide (32), tiodonium chloride (36), toliodium chloride (36), toloconium metilsulfate (17), tonzonium bromide (14), triclobisonium chloride (10)

(c)

domiphen bromide (23)

other agents

amezinium metilsulfate (36), amprolium chloride (16), azaspirium chloride (25), bephenium hydroxynaphthoate (11), bibenzonium bromide (12), bidimazium iodide (27), bretylium tosilate (10), butopyrammonium iodide (8), carcainium chloride (36), clofilium phosphate (42), datelliptium chloride (57), detajmium bitartrate (34), dibrospidium chloride (51), ditercalinium chloride (49), edrophonium chloride (4), elliptinium acetate (43), emilium tosilate (37), famiraprinium chloride (58), feniodium chloride (23), gallium (⁶⁷Ga) citrate (33), homidiumbromide (36), isometamidium chloride (18), mefenidramium metilsulfate (52), meldonium (86), mequitamium iodide (61), nolpitantium besilate (75), pinaverium bromide (32), pirdonium bromide (28), prajmalium bitartrate (23), pranolium chloride (32), pretamazium iodide (29), propagermanium (65), prospidium chloride (22), pyritidium bromide (16), pyrvinium chloride (6), quindonium bromide (14), quinuclium bromide (40), repagermanium (63), rimazolium metilsulfate (26), roxolinium metilsulfate (33), samarium (¹⁵³Sm) lexidronam (74), sevitropium mesilate (56), spirogermanium (43), stilbazium iodide (13), thenium closilate (12), tipetropium bromide (42), tolonium chloride (4), trazium esilate (54), trethinium tosilate (14), troxonium tosilate (13), troxypyrrolium tosilate (13)

(c)

alazanine triclofenate (13) (anthelminthic), colfosceril palmitate (64) (pulmonary surfactant), dithiazanine iodide (8) (anthel-minthic), hexadimethrine bromide (8) (heparin antagonist)

-curium (d)

curare-like substances

-izine

diphenylmethyl piperazine derivatives

(-yzine)

(a)

antihistaminics: G.2.0.0: buclizine (4), cetirizine (51), chlorcyclizine (1), clocinizine (15), cyclizine (1), efletirizine (71), elbanizine (60), flotrenizine (48), levocetirizine (78), pibaxizine (62), trenizine (48)

homochlorcyclizine (10) (serotonin antagonist)

tranquillizers: etodroxizine (18), hydroxyzine (6)

various: benderizine (40) (antiarrhythmic), decloxizine (19) (respiratory insufficiency), ropizine (36) (anticonvulsant)

-rizine

antihistaminics/cerebral (or peripheral) vasodilators

belarizine (36), buterizine (42), cinnarizine (11), dotarizine (50), flunarizine (22), lifarizine (66), tagorizine (72), tamolarizine (66), trelnarizine (62)

chemically related: pipoxizine (32) (respiratory insufficiency)

(b)

phenothiazine derivatives: chloracyzine (12) (vasodilator), fluacizine (25) (sedative), moracizine (25) (antiarrhythmic), tiracizine (62) (antiarrhythmic)

benzilate esters: benactyzine (6) (tranquillizer), benaprizine (26) (anti-parkinsonian)

phenylpiperazine: dimetholizine (10) (antiallergic), dropropizine (18)/levodropropizine (64) (antitussive)

antibiotic "cef": cefatrizine (34)

pyrazine derivatives: ampyzine (15) (central nervous stimulant), triampyzine (15) (anticholinergic)

indoloquinolines (anticholinergic): metoquizine (17), toquizine (17)

(c)

medibazine (16)

USAN

-kacin

antibiotics, kanamycin and bekanamycin derivatives (obtained from Streptomyces kanamyceticus)

S.6.3.0

(USAN: antibiotics obtained from Streptomyces kanamyceticus (related to kanamycin))

(a)

amikacin (30), arbekacin (56), butikacin (41), dibekacin (31), propikacin (43)

(c)

bekanamycin (24), kanamycin (10)

other aminoglycoside antibiotics:

Strept. griseus: dihydrostreptomycin (1) (semisynthetic), streptomycin (1), streptoniazid (13) (semisynthetic)

Strept. tenebrarius: apramycin (31), nebramycin (19) (mixture of several antibiotics, including apramycin and tobramycin), tobramycin (28)

Bacillus circularis: butirosin (25)

USAN

-kalant

potassium channel blockers

H.2.0.0

(a)

adekalant (83), almokalant (64), clamikalant (81), nifekalant (75), terikalant (66), pinokalant (82)

BAN, USAN

-kalim

potassium channel activators, antihypertensive

H.3.0.0

(a)

aprikalim (64), bimakalim (64), cromakalim (58)/levcromakalim (66), emakalim (66), mazokalim (75), rilmakalim (65), sarakalim (81)

USAN

-kef-

enkephalin agonists

casokefamide (65), frakefamide (81), metkefamide (44)

-kin

interleukin type substances

S.7.0.0

IL-1:

-nakin

interleukin-1 analogues and derivatives:

-onakin

interleukin-1 analogues and derivatives: pifonakin (77)

-benakin

interleukin-1 analogues and derivatives: mobenakin (72)

IL-2:

-leukin

interleukin-2 analogues and derivatives: aldesleukin (63), celmoleukin (65), denileukin diftitox (78), teceleukin (54)

pegaldesleukin (67)

IL-3:

-plestim

interleukin-3 analogues and derivatives: muplestim (72)

IL-4:

-trakin

interleukin-4 analogues and derivatives: binetrakin (82)

IL-6:

-exakin

interleukin-6 analogues and derivatives: atexakin alfa (72)

IL-8:

-octakin

interleukin-8 analogues and derivatives: emoctakin (74)

IL-10:

-decakin

interleukin-10 analogues and derivatives: ilodecakin (81)

IL-11:

-elvekin

interleukin-11 analogues and derivatives: oprelvekin (76)

-kinra

interleukin receptor antagonists: pitrakinra (84)

IL-12:

-dodekin

interleukin-12 analogues and derivatives: edodekin alfa (79)

IL-13:

-nakinra

interleukin-1 receptor antagonists: anakinra (72)

USAN

-kiren

renin inhibitors

H.3.0.0

(a)

aliskiren (83), ciprokiren (69), ditekiren (62), enalkiren (61), remikiren (66), terlakiren (66), zankiren (70)

USAN

-lubant

leukotriene B₄ receptor antagonist

(a)

amelubant (85), moxilubant (78), ticolubant (76)

-lukast

leukotriene receptor antagonists, see -ast

BAN, USAN

-mab

monoclonal antibodies (see also Annex)

S.7.0.0

-amab

rat origin

-emab

hamster origin

-imab

primate origin

-omab

mouse origin:

ba(c)

bacterial: edobacomab (69)

co(l)

colon: edrecolomab (74), nacolomab tafenatox (71)

go(v)

ovary (tumours): igovomab (74), oregovomab (86)

li(m)

lymphocyte: afelimomab (72), dorlimomab aritox (66), enlimomab (70), enlimomab pegol (77), faralimomab (76), gavilimomab (84), inolimomab (71), maslimomab (66), nerelimomab (76), odulimomab (73), telimomab aritox (66), vepalimomab (80), zolimomab aritox (69)

ci(r)

cardiovascular: biciromab (66), imciromab (66)

le(s)

infectious lesions: lemalesomab (84), sulesomab (75), technetium (^99mTc) fanolesomab (86)

pr(o)

tumour (prostate): capromab (70)

tu(m)

tumour (miscellaneous): anatumomab mafenatox (79), arcitumomab (74), altumomab (68), bectumomab (75), detumomab (70), epitumomab (82), ibritumomab tiuxetan (81), minretumomab (80), mitumomab (82), satumomab (67), taplitumomab paptox (84), technetium (^99mTc) nofetumomab merpentan (76), technetium (^99mTc) pintumomab (75), tositumomab (80)

-umab

human origin:

ba(c)

bacterial: nebacumab (66)

li(m)

immunomodulator: adalimumab (82), atorolimumab (80), lerdelimumab (83), metelimumab (86), morolimumab (79), ziralimumab (84)

tu(m)

tumour: votumumab (70)

vi(r)

viral: regavirumab (71), sevirumab (66), tuvirumab (66)

-ximab

chimeric origin

ci(r)

cardiovascular: abciximab (70)

li(m)

immunomodulator: basiliximab (76), clenoliximab (77), infliximab (77), keliximab (76), priliximab (72), teneliximab (87), vapaliximab (87)

me(l)

melanoma: ecromeximab (87)

tu(m)

tumor: cetuximab (82), rituximab (77)

(c)

muromonab CD3 (59)

-zumab

humanized origin

ci(r)

cardiovascular: bevacizumab (83)

li(m)

lymphocyte: apolizumab (87), daclizumab (78) (previously: dacliximab), eculizumab (87), efalizumab (85), erlizumab (84), fontolizumab (87), mepolizuma (81), natalizumab (79), omalizumab (84), palivizumab (79), pascolizumab (87), pexelizumab (85), reslizumab (85), rovelizumab (81), ruplizumab (83), siplizumab (87), toralizumab (87), visilizumab (84)

tu(m)

tumor: (miscellaneous): alemtuzumab (83), bivatuzumab (83), cedelizumab (77), epratuzumab (82), gemtuzumab (83), labetuzumab (85), lintuzumab (76), sibrotuzumab (81), trastuzumab (78)

vi(r)

viral: felvizumab (77)

USAN

-mantadine

adamantane derivatives

-mantine

-mantone

(a)

antiviral: S.5.3.0: amantadine (15), rimantadine (17), somantadine (51), tromantadine (28)

antiparkinsonian: E.2.0.0: carmantadine (31), dopamantine (31), memantine (35)

immunostimulant: S.7.0.0: idramantone (71)

(b)

anthelminthic: S.3.1.0: dimantine (14)

(c)

adamexine (36) (mucolytic), amantocillin (17) (antibiotic), bolmantalate (16) (anabolic)

USAN

-meline

cholinergic agents (muscarine receptor agonists/partial antagonists used in the treatment of Alzheimer's disease)

E.1.0.0

alvameline (79), cevimeline (76), itameline (71), milameline (74), sabcomeline (76), tazomeline (77), xanomeline (70)

mer- or -mer- (d)

¹mercury-containing drugs, antimicrobial or diuretic (deleted from General Principles in List 28 prop. INN)

(a)

S.2.2.0 antimicrobial: meralein sodium (13), merbromin (1), mercurobutol (1), otimerate sodium (51), phenylmercuric borate (4), sodium timerfonate (13), thiomersal (1)

¹mer- and -mer- can be used for any type of substances and are no longer restricted to use in INNs for mercury-containing drugs (18th Consultation on INNs 1988)

N.1.3.0 diuretic: chlormerodrin (4), chlormerodrin (197 Hg) (24), meralluride (1), mercaptomerin (1), mercuderamide (1), mercumatilin sodium (4), mercurophylline (1), merisoprol (197 Hg) (24) (diagnostic), mersalyl (4)

(b)

difemerine (17) (spasmolyt.), dimercaprol (1) (antidote, -SH group), lomerizine (68), (cerebral vasodilator), mercaptopurine (6) (cytostatic, -SH group), nifurmerone (16), pemerid (25)

(antituss.), suxemerid (25) (antituss.)

(c)

hydrargaphen (10)

USAN

-mer

polymers:

(a)

amilomer (33), cadexomer (60), carbetimer (50), carbomer (21), crilanomer (53), dextranomer (33), eldexomer (51), leuciglumer (68), maletamer (14), poloxamer (34), porfimer sodium (64), sevelamer (77), surfomer (44), zinostatin stimalamer (74)

(b)

succimer (42)

-mesine

sigma receptor ligands

igmesine (68), panamesine (73), siramesine (81)

USAN

-mestane

aromatase inhibitors

L.0.0.0/Q.2.1.0

exemestane (65), formestane (66), minamestane (64)

met(h)asone

see pred

BAN, USAN

-metacin (x)

anti-inflammatory, indometacin derivatives

A.4.2.0

(BAN: anti-inflammatory substances of the indomethacin group)

(USAN: -methacin: anti-inflammatory substances (indomethacin type))

(a)

acemetacin (32), cinmetacin (24), clometacin (27), delmetacin (48) (originally demetacin (42)), duometacin (27), glucametacin (32), indometacin (13), niometacin (33), oxametacin (37), pimetacin (47), proglumetacin (35), sermetacin (36), talmetacin (46), zidometacin (39)

other anti-inflammatory, indole derivatives: etoprindole (22), indopine (12), indoxole (17), nictindole (28)

USAN

-micin

antibiotics obtained from various Micromonospora

(S.6.5.0)

(USAN: antibiotics (Micromonospora strains))

astromicin (44), betamicin (38), etisomicin (47), evernimicin (82), gentamicin (22), isepamicin (54), maduramicin (52), megalomicin (37), micronomicin (45), mirosamicin (58), netilmicin (36), ozogamicin (83), pentisomicin (41), repromicin (37), rosaramicin (41) (prev. rosamicin), semduramicin (60), sisomicin (25)

TRS 581

-mifene

see -ifene

mito- (d)

antineoplastics, nucleotoxic agents (deleted from General Principles in List 24 prop. INN)

L.0.0.0

(a)

mitobronitol (20), mitocarcin (25), mitoclomine (18), mitoflaxone (60), mitogillin (17), mitoguazone (20), mitolactol (26), mitomalcin (19), mitomycin (26), mitonafide (40), mitopodozide (17), mitoquidone (54), mitosper (24), mitotane (21), mitotenamine (17), mitoxantrone (44), mitozolomide (51)

mitindomide (48)

USAN

-monam

monobactam antibiotics

S.6.0.0

(a)

carumonam (51), gloximonam (54), oximonam (54), pirazmonam (58), tigemonam (57)

(c)

aztreonam (48)

USAN

-mostim

see -stim

USAN

-motine

antivirals, quinoline derivatives (19th Report 1970)

S.5.3.0

(USAN: antiviral quinoline derivatives)

famotine (23), memotine (22)

-moxin (d)

monoamine oxidase inhibitors, hydrazine derivatives*

C.3.1.0

(a)

benmoxin (20), cimemoxin (17), domoxin (14), octamoxin (15)

*not part of definition

(c)

carbenzide (11), etryptamine (12), fenoxypropazine (12), iproclozide (13), iproniazid (1), isocarboxazid (11), mebanazine (15), nialamide (10), pargyline (13), phenelzine (10), pheniprazine (11), tranylcypromine (11)

TRS 581

USAN

-mustine

antineoplastic, alkylating agents, (β-chloroethyl)amine derivatives

L.2.0.0

(USAN: antineoplastic agents ([β-chlorethyl]amine derivatives))

(a)

alestramustine (68), ambamustine (60), atrimustine (61), bendamustine (48), bofumustine (44), carmustine (24), ditiomustine (49), ecomustine (61), elmustine (49), estramustine (24), fotemustine (57), galamustine (61), lomustine (27), mannomustine (8), neptamustine (48) (originally pentamustine (45)), nimustine (37), prednimustine (31), ranimustine (55), semustine (27), spiromustine (47), tallimustine (68), tauromustine (50), uramustine (13)

(c)

chlorambucil (6), chlormethine (1), chlornaphazine (1), cyclophosphamide (10), defosfamide (12), ifosfamide (23), mafosfamide (51), melphalan (8), mitoclomine (18), mitotenamine (17), perfosfamide (66), sarcolysin (17), sufosfamide (36), trichlormethine (11), trofosfamide (23)

TRS 581

BAN, USAN

-mycin (x)

antibiotics, produced by Streptomyces strains (see also -kacin)

S.6.0.0

(USAN: antibiotics, Streptomyces strains)

(a)

amfomycin (12), antelmycin (15), apramycin (31), avilamycin (46), azalomycin (26), azithromycin (58), bambermycin (21), bekanamycin (24), berythromycin (26), bicozamycin (38), biniramycin (23), bluensomycin (14), capreomycin (12), carbomycin (1), cethromycin (87), clarithromycin (59), clindamycin (21), coumamycin (15), daptomycin (58), dihydrostreptomycin (1), diproleandomycin (33), dirithromycin (53), efrotomycin (53), endomycin (6), enramycin (23), enviomycin (31), erythromycin (4), estomycin (14 - deleted in List 28), flurithromycin (51), fosfomycin (25), fosmidomycin (46), ganefromycin (68), hachimycin (23), heliomycin (25), hydroxymycin (8 - deleted in List 28), josamycin (23), kanamycin (10), kitasamycin (13), laidlo-mycin (61), lexithromycin (65), lincomycin (13), lividomycin (32), maridomycin (32), midecamycin (30), mikamycin (17), mirincamycin (31), mocimycin (28), natamycin (15), nebramycin (19), neomycin (1), neutramycin (15), oleandomycin (6), paldimycin (55), paromomycin (10), paulomycin (47), pirlimycin (47), primycin (38), pristinamycin (12), ranimycin (20), relomycin (15), ribostamycin (27), rifamycin (13), rokitamycin (53), roxithromycin (54), salinomycin (37), sedecamycin (55), spectinomycin (13), spiramycin (6), stallimycin (30), steffimycin (20), streptomycin (1), telithromycin (80), terdecamycin (65), tobramycin (28), troleandomycin (24), trospectomycin (53), tulathromycin (87) (vet.), vancomycin (6), viomycin (4), virginiamycin (18)

antibiotics, antineoplastics:

ambomycin (13), antramycin (17), azotomycin (13), bleomycin (23), cactinomycin (15), dactinomycin (18), duazomycin (13), lucimycin (13), mitomycin (26), nogalamycin (16), olivomycin (18), peliomycin (15), peplomycin (44), plicamycin (50) (previously mithramycin (16)), porfiromycin (15), puromycin (15), rufocromomycin (12), sparsomycin (13), talisomycin (41)

antibiotics, antineoplastics, antibacterial:

cirolemycin (21)

antibiotic, antifungal:

hamycin (17), lidimycin (20), rutamycin (14)

(c)

antibiotic, antibacterial:

aspartocin (11), azidamfenicol (14), cetofenicol (14), chloramphenicol (1), cloramfenicol pantotenate comp. (14), cycloserine (6), novobiocin (6), ostreogrycin (6), rifamide (15), rifampicin (17), streptoniazid (13), streptovarycin (6), thiamphenicol (10), tylosin (16)

antibiotic, antifungal:

amphotericin B (10), candicidin (17), filipin (20), kalafungin (20), nystatin (6), viridofulvin (16)

antibiotic, antineoplastic:

daunorubicin (20), mitomalcin (19), streptonigrin (14) (deleted in List 33)

see also -rubicin

USAN

nab

cannabinol derivatives

(USAN: -nab; or -nab-: cannabinol derivatives)

(a)

cannabinol (23), dronabinol (51), menabitan (49), nabazenil (49), nabilone (49), nabitan (42), naboctate (45), nonabine (47), pirnabin (41), rimonabant (83), tinabinol (49)

(b)

fenabutene (26), guanabenz (26), muromonab-CD3 (59), nabumetone (44)

USAN

nal-

narcotic antagonists/agonists related to normorphine

A.4.1.0

B.2.0.0

(USAN: arcotic agonists or antagonists related to normorphine)

a)

nalbuphine (21), nalfurafine (87), nalmefene (49) (originally nalmetrene (47)), nalmexone (19), nalorphine (1), naloxone (13), naltrexone (29)

(b)

nalidixic acid (13)

TRS 581

-naritide

see -tide

-nermin

see -ermin

-nercept

tumour necrosis factor antagonist

etanercept (81), lenercept (72), onercept (82)

nico- or nic- or ni-

nicotinic acid or nicotinoyl alcohol derivatives

nico-: nicoboxil (43), nicoclonate (29), nicocodine (12), nicocortonide (40), nicodicodine (15), nicofibrate (31), nicofuranose (14), nicofurate (28), nicomol (23), nicomorphine (7), nicopholine (1), nicorandil (44), nicothiazone (10), nicotinamide (4), nicotinic acid (4), nicotredole (72), nicoxamat (44), nikethamide (4)

inositol nicotinate (16), xantinol nicotinate (16)

nic-: nicafenine (40), nicainoprol (46), nicametate (15), nicardipine (42), nicanartine (72), nicergoline (26), niceritrol (23), niceverine (15), nictindole (28), nizofenone (44)

ni-: nialamide (10), niaprazine (24), nifenazone (15), niometacin (33), niprofazone (29), nixylic acid (17)

-nicate:

antihypercholesterolaemic and/or vasodilating nicotinic acid esters

H.4.0.0

F.2.2.0

(a)

ciclonicate (33), derpanicate (58), estrapronicate (34), glunicate (51), hepronicate (22), micinicate (44), pantenicate (56), sorbinicate (33)

(b)

nitrile derivative: nimazone (21)

other: nifungin (24), nimidane (34), nisbuterol (38)

(c)

NO₂ - derivatives: acenocoumarol (6) (anticoag.), azathioprine (12) and tiamiprine (15) (antimetabolites), bronopol (14) (antiseptic), chloramphenicol (1) (antibiotic), clonazepam (22) (sed.), flurantel (25) (anthelmintic), flutamide (33) (nonsteroid anti-androgen)

nitro- or nitr- or nit- or ni- or -ni-

NO₂ - derivatives

nifur- all INNs of this series (see under nifur-)

nitro-: nitroclofene (41), nitrocycline (14), nitrodan (15), nitrofural (1), nitrofurantoin (11), nitromifene (33), nitroscanate (33), nitrosulfathiazole (1), nitroxinil (19), nitroxoline (15)

nitr-: nitracrine (35), nitrafudam (40), nitramisole (33), nitraquazone (53), nitrazepam (16), nitrefazole (46), nitricholine perchlorate (6)

nit- and -nit-: nitarsone (17), ranitidine (41)

ni-: nibroxane (35), niclofolan (20), niclosamide (13), nidroxyzone (6), nifenalol (22), nihydrazone (10), nimesulide (44), nimorazole (22), niridazole (17)

ni-dipine: nicardipine (42), nifedipine (27), niludipine (38), nisoldipine (42), nitrendipine (42), vatamidipine (77)

-nidazole: for INNs of this series see under -nidazole

BAN, USAN

-nidazole (x)

antiprotozoals, metronidazole derivatives

S.3.3.0

(USAN: antiprotozoal substances (metronidazole type))

Y.0.0.0

(a)

abunidazole (52), azanidazole (38), bamnidazole (37), benznidazole (31), carnidazole (32), etanidazole (57), fexinidazole (37), flunidazole (21), ipronidazole (21), metronidazole (11), misonidazole (38), moxnidazole (33), ornidazole (28), panidazole (24), pimonidazole (57), pirinidazole (32), propenidazole (45), ronidazole (18), satranidazole (48), secnidazole (30), sulnidazole (33), ternidazole (34), tinidazole (21), tivanidazole (48)

(c)

dimetridazole (17), nimorazole (22), stirimazole (25)

TRS 581

-nidine

see -onidine

USAN

nifur- (d)

5-nitrofuran derivatives

S.2.1.0

(a)

nifuradene (16), nifuraldezone (17), nifuralide (34), nifuratel (17), nifuratrone (24), nifurdazil (16), nifurethazone (10), nifurfoline (20), nifurimide (18), nifurizone (22), nifurmazole (22), nifurmerone (16), nifuroquine (36), nifuroxazide (14), nifuroxime (11), nifurpipone (20), nifurpirinol (22), nifurprazine (16), nifurquinazol (18), nifursemizone (16), nifursol (20), nifurthiazole (14), nifurtimox (21), nifurtoinol (36), nifurvidine (17), nifurzide (37)

(c)

furalazine (13), furaltadone (17), furazolidone (13), furazolium chloride (15), furmethoxadone (8), levofuraltadone (17), nidroxyzone (6), nihydrazone (10), nitrofural (1), nitrofurantoin (11), thiofuradene (11)

TRS 581

-nil

see -azenil, also for -carnil, -quinil

USAN

-nixin

anti-inflammatory, anilinonicotinic acid derivatives

A.4.2.0

(a)

butanixin (32), clonixin (22), diclonixin (31), flunixin (31), isonixin (34), metanixin (31)

(c)

clonixeril (22), niflumic acid (17), nixylic acid (17)

TRS 581

-ol (d)

for alcohols and phenols (deleted from General Principles in 14th Report)

BAN, USAN

-olol (x)

β-adrenoreceptor antagonists

E.5.2.0

(BAN: beta-adrenoreceptor antagonists)

(BAN: beta adrenoreceptor blocking agents of the propranolol group)

(USAN: beta-blockers)

(a)

acebutolol (28), adaprolol (63), adimolol (50), afurolol (40), alprenolol (19), ancarolol (47), arnolol (56), arotinolol (48), atenolol (33), befunolol (39), betaxolol (40), bevantolol (36), bisoprolol (48), bometolol (42), bopindolol (42), bornaprolol (46), bucindolol (43), bucumolol (35), bufetolol (30), bunitrolol (28), bunolol (22), bupranolol (27), butocrolol (38), butofilolol (40), carazolol (36), carpindolol (42), carteolol (35), celiprolol (35), cetamolol (47), cicloprolol (48), cinamolol (44), cloranolol (41), crinolol (41) (replaced by pacrinolol (44)), dexpropranolol (21), diacetolol (41), draquinolol (54), ecastolol (56), epanolol (52), ericolol (50), esatenolol (76), esmolol (50), exaprolol (32), falintolol (53), flestolol (53), flusoxolol (50), idropranolol (31), imidolol (49) (replaced by adimolol (50)), indenolol (37), indopanolol (48), iprocrolol (39), isoxaprolol (45), landiolol (75), levobetaxolol (61), levobunolol (42), levomoprolol (58), mepindolol (36), metipranolol (38), metoprolol (30), moprolol (36), nadolol (34), nadoxolol (28), nafetolol (39), nebivolol (56), nipradilol (50) (previously nipradolol (49)), oxprenolol (20), pacrinolol (44), pafenolol (46), pamatolol (36), pargolol (36), penbutolol (25), penirolol (36), pindolol (23), pirepolol (48), practolol (23), primidolol (42), procinolol (25), propranolol (15), ridazolol (51), ronactolol (57), soquinolol (43), spirendolol (46), talinolol (28), tazolol (31), teoprolol (43), tertatolol (48), tienoxolol (56), tilisolol (57), timolol (29), tiprenolol (23), tolamolol (29), toliprolol (28), trigevolol (56), xibenolol (48), xipranolol (22)

(b)

Q.2.3.0: stanozolol (18) (anabolic steroid)

TRS 581

-alol

aromatic ring

-CH-CH₂-NH-R related to -olols

OH

(USAN: combined alpha and beta blockers)

amosulalol (50), bendacalol (59), brefonalol (56), bufuralol (31), dexsotalol (74), dilevalol (50), labetalol (35), medroxalol (43), nifenalol (22), pronetalol (14), sotalol (18), sulfinalol (41), butidrine (16)

(c)

butidrine (16)

USAN

-olone

see pred

-one (d)

ketones

(a)

448 (9.62%) INNs ending in -one in Lists 1-48 of Proposed INNs

BAN, USAN

-onide

steroids for topical use, acetal derivatives

Q.3.0.0

(a)

acrocinonide (27), amcinonide (33), budesonide (37), ciclesonide (62), cicortonide (28), ciprocinonide (38), desonide (24), dexbudesonide (80), drocinonide (29), fluclorolone acetonide (22), fluocinolone acetonide (11), flumoxonide (38), fluocinonide (25), halcinonide (29), itrocinonide (62), nicocortonide (40), procinonide (38), rofleponide (72), tralonide (27), triamcinolone benetonide (36), triamcinolone furetonide (36), triamcinolone hexacetonide (15), triclonide (30)

(c)

amcinafal (25), amcinafide (25)

TRS 581

-onidine

antihypertensives, clonidine derivatives

H.3.0.0

(a)

apraclonidine (59) (control of intraocular pressure), benclonidine (42), brimonidine (66), clonidine (40), flutonidine (31), moxonidine (48), piclonidine (44), tolonidine (28)

related: alinidine (40) (analgesic)

-nidine

H.3.0.0

(a)

related antihypertensives: betanidine (13), indanidine (50), rilmenidine (57), tiamenidine (28)

(b)

muscle relaxant: tizanidine (43)

topical antiinfective: octenidine (43), pirtenidine (57)

antibacterial: sulfaguanidine (4)

vet. coccidiostat: robenidine (25)

(c)

dexlofexidine (48), levlofexidine (48), lofexidine (33)

-onium

see -ium

-opamine

see -dopa

BAN, USAN

-orex

anorexics

M.1.0.0

(BAN: anorexic agents, phenethylamine derivatives)

(USAN: anorexants)

(a)

acridorex (21), amfepentorex (16), aminorex (14), benfluorex (25), clobenzorex (18), cloforex (16), clominorex (14), difemetorex (41), etolorex (20), fenisorex (29), fenproporex (17), flucetorex (30), fludorex (19), fluminorex (14), formetorex (14), furfenorex (16), indanorex (30), mefenorex (19), morforex (26), oxifentorex (20), pentorex (16), picilorex (40), tiflorex (34)

(c)

amfebutamone (31), amfecloral (12), amfepramone (13), amfetamine (55), amfetaminil (40), benzfetamine (55), brolamfetamine (55), chlorphentermine (11), clortermine (22), dexamfetamine (55), dimetamfetamine (38), etilamfetamine (40), fenbutrazate (12),

fenfluramine (14), hexapradol (12), levamfetamine (12), mephentermine (6), ortetamine (13), phendimetrazine (11), phenmetrazine (6), phentermine (11)

TRS 581

orphan

narcotic antagonists/agonists, morphinan derivates

A.4.1.0

B.2.0.0

(USAN: -orphan: morphinan derivatives that are narcotic antagonists or agonists)

(a)

A.4.1.0: butorphanol (31), dextromethorphan (1), dextrorphan (1), dimemorfan (30), ketorfanol (49), levomethorphan (1), levophenacylmorphan (9), levorphanol (4), norlevorphanol (9), oxilorphan (31), phenomorphan (5), proxorphan (43), racemethorphan (1), racemorphan (1), xorphanol (48)

TRS 581

B.2.0.0: levallorphan (2)

-orph-

-orphine: acetorphine (17), alletorphine (25), buprenorphine (29), cyprenorphine (17), desomorphine (5), diprenorphine (21), etorphine (17), homprenorphine (25), methyldesorphine (5), methyldihydro-morphine (5), nalorphine (1), nicomorphine (7), normorphine (7)

-orphinol: hydromorphinol (11)

-orphone: conorfone (46), hydromorphone (1), oxymorphone (5), pentamorphone (60), semorphone (67)

(b)

emorfazone (44), morforex (26), morpheridine (6), orphenadrine (8)

-ox

antacids, aluminium derivatives: glucalox (13), sucralox (13)

-alox

-dox

antibacterials, quinazoline dioxide derivatives:

carbadox (19), ciadox (44), cinoquidox (40), drazidox (24), mequidox (19), olaquindox (31), temodox (27)

-pirox

antimycotic pyridone derivatives:

ciclopirox (26), metipirox (26), rilopirox (56)

USAN

-xanox

anti-allergics, tixanox group:

(a)

amlexanox (55), mepixanox (49), sudexanox (44), tixanox (37), traxanox (44)

(c)

xanoxic acid (33)

others:

bifeprunox (87) (antipsychotic), cefminox (53) (antibiotic), deferasirox (86) (chelating agent), nifurtimox (21) (antiprotozoal), sulbenox (37) (animal growth regulator), acipimox (33) (antilipemic), etofenprox (57) (insecticide)

BAN, USAN

-oxacin (x)

antibacterials, nalidixic acid derivatives

S.5.5.0

(BAN: antibacterial agents of the cinoxacin group)

(USAN: antibacterial agents (nalidixic acid type))

(a)

alatrofloxacin (75), amifloxacin (51), balofloxacin (71), binfloxacin (60), cadrofloxacin (81), cetefloxacin (68), cinoxacin (32), ciprofloxacin (50), clinafloxacin (67), danofloxacin (61), difloxacin (55), droxacin (36), ecenofloxacin (78), enoxacin (49), enrofloxacin (56), esafloxacin (60), fandofloxacin (78), finafloxacin (85), fleroxacin (56), garenoxacin (87), gatifloxacin (74), gemifloxacin (81), grepafloxacin (68), ibafloxacin (60), irloxacin (53), levofloxacin (64), lomefloxacin (58), marbofloxacin (65), merafloxacin (69), miloxacin (40), moxifloxacin (78), nadifloxacin (64), norfloxacin (46), ofloxacin (49), olamufloxacin (79), orbifloxacin (68), pazufloxacin (71), pefloxacin (45), pradofloxacin (84), premafloxacin (72), prulifloxacin (72), rosoxacin (36), rufloxacin (57), sarafloxacin (62), sitafloxacin (75), sparfloxacin (63), temafloxacin (58), tioxacin (34), tosufloxacin (60), trovafloxacin (73), vebufloxacin (69)

(c)

flumequine (34), nalidixic acid (13), oxolinic acid (15), pipemidic acid (32), piromidic acid (27)

metioxate (34)

USAN

-oxan(e)

benzodioxane derivatives

E.5.1.0

(USAN: -adrenoreceptor antagonists; benzodioxane derivatives)

(a)

-adrenoreceptor antagonists

azaloxan (52) (antidepressant), fluparoxan (58) (antidepressant), idazoxan (49) (α₂), imiloxan (52) (α₂) (antidepressant), piperoxan (1) (sympatholytic), proroxan (39)

antihypertensives:

flesinoxan (55), guabenxan (32), guanoxan (15)

tranquillizers:

butamoxane (12), ethomoxane (12), pentamoxane (12)

related:

efaroxan (59) (α₂)

(b)

ambenoxan (21), amoproxan (22), nibroxane (35), razoxane (40)/dexrazoxane (62), sobuzoxane (62), tolboxane (12)

USAN

-oxanide

see -anide

USAN

-oxef

see cef-

-oxepine

see -pine

USAN

-oxetine

antidepressants, fluoxetine derivatives

C.3.0.0

(a)

ansoxetine (58), dapoxetine (65), duloxetine (68), femoxetine (36), fluoxetine (34), ifoxetine (54), litoxetine (64), nisoxetine (34), omiloxetine (76), paroxetine (38), reboxetine (54), seproxetine (66), tomoxetine (49)

-oxifene

see -ifene

-oxicam

see -icam

BAN, USAN

-pafant

platelet-activating factor antagonists

I.2.1.0

(a)

apafant (60), bepafant (60), dacopafant (63), foropafant (75), israpafant (76), lexipafant (70), minopafant (80), modipafant (65), nupafant (70), rocepafant (71), setipafant (72), tulopafant (64)

USAN

-pamide

diuretics, sulfamoylbenzoic acid derivatives

(could be sulfamoylbenzamide) (19th Report, 1970)

N.1.2.0

(USAN: diuretics (sulfamoylbenzoic acid derivatives))

(a)

alipamide (18), besulpamide (52), clopamide (13), indapamide (29), tripamide (44), xipamide (22), zidapamide (50) (previously isodapamide (47))

(b)

chlorpropamide (8) (hypoglycemic), isopropamide iodide (8) (anticholinergic)

(c)

bumetanide (24), chlortalidone (12), clorexolone (15), furosemide (14), sulclamide (15), tiamizide (16)

USAN

-pamil

coronary vasodilators, verapamil derivatives

F.2.1.0

(USAN: coronary vasodilators (verapamil type))

(a)

anipamil (49), dagapamil (52), devapamil (53), dexverapamil (65), emopamil (52), falipamil (48), gallopamil (38), levemopamil (62), nexopamil (67), ronipamil (51), tiapamil (43), verapamil (16)

related: bertosamil (64), bisaramil (60)

USAN

-parcin

for glycopeptide antibiotics

S.6.0.0

(a)

avoparcin (29), orientiparcin (72)

USAN

-parin

heparin derivatives including low molecular mass heparins

I.2.0.0

(a)

ardeparin sodium (68), bemiparin sodium (75), certoparin sodium (70), dalteparin sodium (64), enoxaparin sodium (52), heparin sodium (54), livaraparin calcium (85), minolteparin sodium (73), nadroparin calcium (65), parnaparin sodium (65), reviparin sodium (65), tinzaparin sodium (65)

-parinux

synthetic heparinoids

fondaparinux sodium (83) (replaces fondaparin sodium (79))

USAN

-penem

analogues of penicillanic acid antibiotics modified in the five-membered ring

S.6.0.0

(USAN: analogues of penicillanic acid antibiotics modified in the five-membered ring)

(a)

biapenem (69), doripenem (83), ertapenem (84), faropenem (69), imipenem (50), lenapenem (73), meropenem (60), panipenem (64), ritipenem (67), sulopenem (68), tacapenem (87), tebipenem (82)

USAN

-perone

tranquillizers, neuroleptics, 4'-fluoro-4-piperidinobutyrophenone derivatives

C.1.0.0

C.2.0.0

(USAN: 4'-fluoro-4-piperidinobutyrophenone derivatives; antianxiety agents; neuroleptics)

(a)

aceperone (14), amiperone (14), biriperone (51), carperone (24), cicarperone (28), cinuperone (53), cloroperone (38), declenperone (42), duoperone (54), fenaperone (28), fluspiperone (34), lenperone (27), lodiperone (44), melperone (34), metrenperone (56), milenperone (37), mindoperone (38), moperone (14), nonaperone (44), pipamperone (17), pirenperone (46), prideperone (54), primaperone (17), propyperone (16), roxoperone (17), setoperone (51), spiperone (17), timiperone (40) closely related: azabuperone (34), azaperone (18), lodiperone (44), zoloperone (39)

USAN

-peridol

antipsychotics, haloperidol derivatives

benperidol (14), bromperidol (33), [clofluperol (18)], droperidol (14), [fluanisone (13)], haloperidol (10), trifluperidol (16)

USAN

-peridone

antipsychotics, risperidone derivatives

abaperidone (80), belaperidone (78), cloperidone (17), iloperidone (69), lusaperidone (82), ocaperidone (64), paliperidone (83), risperidone (57), tioperidone (37)

(c)

domperidone (36), etoperidone (36) (antiemetic)

USAN

-pidem

hypnotics/sedatives, zolpidem derivatives

C.1.0.0

alpidem (53), necopidem (66), saripidem (67), zolpidem (53)

-pin(e)

see also Pharm S/Nom 970 (tricyclic compounds)

-dipine

see -dipine

(a)

-zepine

antidepressant/neuroleptic: C.3.2.0: dibenzepin (14), elanzepine (35), enprazepine (30), mezepine (22), nuvenzepine (59), prazepine (15), propizepine (19), tilozepine (40)

tricyclic antiulcer: J.0.0.0: darenzepine (52), pirenzepine (30), siltenzepine (63), telenzepine (50), zolenzepine (48)

tricyclic anticonvulsant: A.3.1.0: carbamazepine (15), etazepine (51), licarbazepine (81), oxcarbazepine (41)

hyperthermia: amezepine (42)

-apine

psychoactive: C.0.0.0: amoxapine (25), asenapine (87), batelapine (64), clotiapine (16), clozapine (22), flumezapine (47), fluperlapine (46), loxapine (22), metiapine (22), mirtazapine (61), olanzapine (67), pentiapine (56), perlapine (23), quetiapine (74), rilapine (52), serazapine (63), tenilapine (52)

-cilpine

antiepileptic: A.3.1.0: dizocilpine (60)

-oxepin

beloxepin (75), cidoxepin (17), doxepin (15), maroxepin (54), metoxepin (33), pinoxepin (18), savoxepin (56), spiroxepin (32)

-oxopine

traboxopine (58)

-sopine

adosopine (63)

-tepine

citatepine (54), clorotepine (29), damotepine (27), metitepine (27), tropatepine (28)

dosulepin (15)

(b)

atromepine (15), noscapine (7), prozapine (14)

(c)

clobenzepam (25), homopipramol (20), opipramol (15)

-piprazole

see -prazole

USAN

-pirox

see -ox

-pirone

see -spirone

-plact

platelet factor 4 analogues and derivatives

iroplact (74)

USAN

-planin

antibacterials (Actinoplanes strains)

S.5.0.0

actaplanin (34), mideplanin (66), ramoplanin (57), teicoplanin (48)

-plase

see -teplase, -uplase under -ase

USAN

-platin

antineoplastic agents, platinum derivatives

L.0.0.0

(USAN: antineoplastics (platinum derivatives))

(a)

carboplatin (48), cisplatin (39), dexormaplatin (64), enloplatin (64), eptaplatin (83), iproplatin (51), lobaplatin (65), miboplatin (66), miriplatin (85), nedaplatin (67), ormaplatin (63), oxaliplatin (56), picoplatin (87), satraplatin (80), sebriplatin (68), spiroplatin (48), triplatin tetranitrate (87), zeniplatin (63)

-plon

pyrazolo[.]pyrimidine derivatives, used as anxiolytics, sedatives, hypnotics

A.2.2.0

C.1.0.0

ocinaplon (72), indiplon (86), zaleplon (72)

BAN, USAN

-poetin

erythropoietin type blood factors

I.0.0.0

(a)

darbepoetin alfa (85), epoetin alfa (62), epoetin beta (62), epoetin delta (85), epoetin gamma (67), epoetin epsilon (72), epoetin omega (73)

USAN

-porfin

benzoporphyrin derivatives

(a)

rostaporfin (83), stannsoporfin (79), talaporfin (83), temoporfin (70), verteporfin (71)

-poride

Na⁺/H⁺ antiport inhibitor

amiloride (18), cariporide (74), eniporide (79), sabiporide (84), zoniporide (85)

BAN, USAN

-pramine

substances of the imipramine group

C.3.2.0

(USAN: imipramine type compounds)

(a)

saturated dibenzazepine:

azipramine (36), carpipramine (16), cianopramine (47), ciclopramine (29), clocapramine (28), clomipramine (17), depramine (31), desipramine (13), imipramine (8), ketimipramine (17), lofepramine (24), lopramine (24) (replaced by lofepramine (34)), metapramine (34), mosapramine (64), pumaprazole (76), quinupramine (32), tampramine (54), tienopramine (38), trimipramine (13), imipraminoxide (36)

(c)

unsaturated dibenzazepine:

carbamazepine (15), homopipramol (20), opipramol (15)

TRS 581

USAN

-prazole

antiulcer, benzimidazole derivatives

J.0.0.0

(USAN: antiulcerative benzimidazole derivatives)

(a)

cinprazole (34), disuprazole (56), esaprazole (45), esomeprazole (79), fuprazole (39), ilaprazole (86), lansoprazole (60), leminoprazole (68), nepaprazole (74), nilprazole (37), omeprazole (46), pantoprazole (62), picoprazole (46), pumaprazole (76), rabeprazole (69), saviprazole (62), tenatoprazole (80), timoprazole (35), ufiprazole (58)

-piprazole

psychotropics, phenylpiperazine derivatives

C.0.0.0

(a)

aripiprazole (75), dapiprazole (45), elopiprazole (70), enpiprazole (24), lorpiprazole (60), mepiprazole (24), sonepiprazole (80) tolpiprazole (25)

(b)

dapiprazole (see above)

USAN

pred

prednisone and prednisolone derivatives

Q.3.3.0

(USAN: pred-; -pred- or -pred)

(a)

chloroprednisone (12), cloprednol (31), difluprednate (21), domoprednate (47), fluprednidene (19), fluprednisolone (13), halopredone (36), isoflupredone (36), isoprednidene (24), loteprednol (64), mazipredone (32), meprednisone (15), methylprednisolone (8), methylprednisolone aceponate (52), methylprednisolone suleptanate (56), oxisopred (29), prednazate (16), prednazoline (22), prednicarbate (44), prednimustine (31), prednisolamate (13), prednisolone (6), prednisolone steaglate (16), prednisone (6), prednylidene (13), tipredane (54)

(c)

-methasone or -metasone: alclometasone (41), amelometasone (74), beclometasone (17), betamethasone (11), betamethasone acibutate (26), cormetasone (29), desoximetasone (20), dexamethasone (8), dexamethasone acefurate (57), flumetasone (13), halometasone (41), icometasone enbutate (70), mometasone (56), paramethasone (12)

-betasol: clobetasol (26), doxibetasol (26), ulobetasol (54)

(USAN: steroids (not prednisolone derivatives))

Q.3.0.0

-olone: clocortolone (16), descinolone (17), diflucortolone (18), fluclorolone acetonide (22), fluocinolone acetonide (11), fluocortolone (15), fluorometholone (8), fluperolone (13), ganaxolone (76), halocortolone (31), rimexolone (38), triamcinolone (8), triamcinolone benetonide (36), triamcinolone furetonide (36), triamcinolone hexacetonide (15)

clobetasone (26), cloticasone (52), deprodone (20), dichlorisone (10), diflorasone (30), flunisolide (11), fluticasone (52), meclorisone (40), timobesone (51)

-olone

steroids other than prednisolone derivatives

A.1.2.0

general anesthetics, pregnanes: alfadolone (27), alfaxalone (27), minaxolone (39), renanolone (8)

H.2.0.0

anti-arrhythmic: amafolone (40), edifolone (56)

L.6.0.0

cytostatics - sex hormones: drostanolone (13), trestolone (25)

Q.2.3.0

androgens: androstanolone (4), drostanolone (13), mesabolone (29), mestanolone (10), mesterolone (15), metenolone (12), metribolone (17), nandrolonoe (22), norethandrolone (6), oxabolone cipionate (14), oxandrolone (12), oxymetholone (11), quinbolone (14), rosterolone (59), stenbolone (17), tibolone (22), trenbolone (24)

J.0.0.0

glycyrrhetic acid derivatives: carbenoxolone (15), cicloxolone (33), cinoxolone (33), deloxolone (51), enoxolone (15), roxolonium metilsulfate (33)

Q.2.3.1

oxendolone (42)

various non-steroidal compounds

citiolone (23) (hepato-bil.troubles), clorexolone (15) (diuretic), fenozolone (14) (psychotonic), tioxolone (16) (keratolytic), vistatolon (25) (antiviral)

TRS 581

-prenaline

see -terol

USAN

-pressin

vasoconstrictors, vasopressin derivatives

Q.1.2.0

(a)

argipressin (13), desmopressin (33), felypressin (13), lypressin (13), ornipressin (22),

terlipressin (46), vasopressin injection (16)

TRS 581

BAN, USAN

-pride (x)

sulpiride derivatives

C.0.0.0

J.1.0.0

(a)

C.0.0.0: alizapride (43), alpiropride (49), amisulpride (44), batanopride (61), broclepride (43), cisapride (49), dazopride (50), denipride (58), etacepride (52), eticlopride (52), flubepride (35), nemonapride (63) (previously emonapride (61)), peralopride (43), prosulpride (43), prucalopride (78), sulmepride (43), sultopride (26), sulverapride (44), veralipride (43)

J.1.0.0: alepride (40), bromopride (27), cinitapride (41), cipropride (41), clebopride (32), dobupride (57), irolapride (55), isosulpride (36), itopride (66), lintopride (65), lirexapride (74), lorapride (44), mezacopride (56), mosapride (66), pancopride (62), raclopride (52), remoxipride (49), renzapride (60), tiapride (28), ticalopride (83), tinisulpride (44), trazolopride (51), tropapride (48), zacopride (55)

K.0.0.0: cloxacepride (42)

U.1.1.0/C.0.0.0: iolopride (¹²³I) (73)

(b)

glimepride (66)

(c)

C.0.0.0: levosulpiride (63), sulpiride (18)

J.1.0.0: metoclopramide (17)

BAN, USAN

-pril (x)

angiotensin-converting enzyme inhibitors

H.3.0.0

(BAN: inhibitors of angiotensin-converting enzyme)

(USAN: antihypertensive agents (captopril type))

(a)

alacepril (50), benazepril (58), captopril (39), ceronapril (64), cilazapril (53), delapril (54), enalapril (46), fosinopril (56), idrapril (66), imidapril (60), indolapril (50), libenzapril (58), lisinopril (50), moexipril (60), moveltipril (58), orbutopril (57), pentopril (53), perindopril (53), pivopril (52), quinapril (54), ramipril (52), rentiapril (55), spirapril (56), temocapril (64), trandolapril (53), utibapril (63), zabicipril (58), zofenopril (51)

-prilat (x)

(a)

benazeprilat (58), cilazaprilat (54), enalaprilat (50), fosinoprilat (62), imidaprilat (71), moexiprilat (67), perindoprilat (56), quinaprilat (60), ramiprilat (53), spiraprilat (60), temocaprilat (78), trandolaprilat (60), utibaprilat (65), zabiciprilat (64), zofenoprilat (63)

USAN

-prim

antibacterials, trimethoprim derivatives

S.5.5.0

(a)

aditoprim (49), baquiloprim (56), brodimoprim (44), epiroprim (44), metioprim (42), ormetoprim (21), tetroxoprim (33), trimethoprim (11), vaneprim (48)

(c)

diaveridine (18)

BAN, USAN

-profen (x)

anti-inflammatory agents, ibuprofen derivatives

A.4.2.0

(USAN: anti-inflammatory or analgesic substances (ibuprofen type))

(a)

alminoprofen (40), araprofen (65), atliprofen (74), bakeprofen (61), benoxaprofen (34), bermoprofen (57), bifeprofen (57), carprofen (35), cicloprofen (32), cliprofen (32), dexibuprofen (61), dexindoprofen (49), dexketoprofen (70), esflurbiprofen (56), fenoprofen (26), flunoxaprofen (44), fluprofen (18), flurbiprofen (28), frabuprofen (51), furaprofen (42), furcloprofen (44), hexaprofen (30), ibuprofen (16), indoprofen (32), isoprofen (40), ketoprofen (28), lobuprofen (53), lonaprofen (44), losmiprofen (61), loxoprofen (50), mabuprofen (64), mexoprofen (33), miroprofen (44), odalprofen (66), pelubiprofen (76), piketoprofen (40), pirprofen (32), pranoprofen (38), suprofen (31), tazeprofen (50), tetriprofen (29), tilnoprofen arbamel (74), tioxaprofen (39), vedaprofen (72), ximoprofen (37), zaltoprofen (64), zoliprofen (55)

(b)

aprofene (12) (antispasm. coron. vasodil.), diprofene (12) (antispasm. blood vessels)

(c)

brofezil (31), protizinic acid (27), tiaprofenic acid (30)

TRS 581

BAN, USAN

prost (x)

prostaglandins

Q.0.0.0

(USAN: -prost- or -prost: prostaglandin derivatives)

(a)

alfaprostol (45), alprostadil (39), ataprost (62), beraprost (59), bimatoprost (85), butaprost (55), carboprost (36), cicaprost (54), ciprostene (51), clinprost (68), cloprostenol (33), delprostenate (42), dimoxaprost (52), dinoprost (26), dinoprostone (26), doxaprost (34), ecraprost (83), eganoprost (84), enisoprost (50), epoprostenol (44), eptaloprost (56), etiproston (46), fenprostalene (42), flunoprost (53), fluprostenol (33), froxiprost (55), gemeprost (42), iloprost (48) (originally ciloprost (46)), lanproston (72), latanoprost (67), limaprost (56), lubiprostone (87), luprostiol (44), meteneprost (45), misoprostol (47), naxaprostene (58), nileprost (45), nocloprost (51), oxoprostol (44), penprostene (37), pimilprost (71), piriprost (51), prostalene (34), remiprostil (65), rosaprostol (48), sulprostone (37), taprostene (58), tiaprost (41), tilsuprost (51), tiprostanide (48), travoprost (80), treprostinil (87), unoprostone (66), vapiprost (58), viprostol (53)

-prostil

prostaglandins, anti-ulcer

(a)

arbaprostil (35), deprostil (32), enprostil (50), mexiprostil (52), ornoprostil (56), rioprostil (49), spiriprostil (63), trimoprostil (49)

TRS 581

-quine (d)

quinoline derivatives (deleted from General Principles in List 28 prop. INN)

quin

(a)

antimalarial: amodiaquine (1), amopyroquine (8), bulaquine (82), chloroquine (4), hydroxychloroquine (8), mefloquine (33), moxipraquine (26), pamaquine (4), pentaquine (4), primaquine (1), quinocide (34), tafenoquine (80), tebuquine (49)

amebicide: clamoxyquine (16), mebiquine (29) (gastrointest. antiseptic), benzoxiquine (18) (antiseptic), cletoquine (20) (anti-inflammatory), cloxiquine (30) (antiseptic), debrisoquine (15) (hypotensive agent), esproquine (31) (cardiovascular agent), flumequine (34) (antibacterial), guanisoquine (15) (hypotensive agent), nifuroquine (36), oxamniquine (28) (schistosomacide)

(c)

antirheumat., antigout (antimalarial): acequinoline (22), cinchophen (1), neocinchophen (1), oxycinchophen (6)

antibact.: actinoquinol (15), aminoquinuride (45), broquinaldol (17), broxaldine (12), chlorquinaldol (1), clioquinol (16), dequalinium chloride (8), diiodohydroxyquinoline (1), laurolinium acetate (12), nitroxoline (15), quindecamine (15), tilbroquinol (45), tiliquinol (45)

antifungal: hedaquinium chloride (8)

anthelmintic: pyrvinium chloride (6)

treatment of leishmaniasis etc: aminoquinol (22), sitamaquine (80)

amebicide: cloquinate (11), dehydroemetine (15), quinfamide (40)

antiproteus: oxolinic acid (15)

coccidiostat: amquinate (21), buquinolate (16), ciproquinate (22), decoquinate (20), nequinate (22), proquinolate (17), quindoxin (26) (growth promoter for pigs and poultry)

growth promoter, bactericide: cinoquidox (40), olaquindox (31) (quinoxaline derivative)

antiviral: famotine (23), memotine (22)