Glyoxalase I, a zinc metalloenzyme of mammals and yeast
Abstract
Glyoxalase I from human and porcine erythrocytes, rat liver, and yeast was shown to contain zinc in a stoichiometry of about 1 mole per mole of enzyme subunit. Removal of zinc by means of a chelator caused elimination of the catalytic activity. The mammalian apoenzymes could be partially reactivated by addition of Zn 2+.
- Publication:
-
Biochemical and Biophysical Research Communications
- Pub Date:
- 1978
- DOI:
- Bibcode:
- 1978BBRC...81.1235A