Conflict of Interest Disclosures: Dr Hawk reported receiving personal fees from Kimmel Comprehensive Cancer Center (CCC) at Johns Hopkins, University of Kansas CCC, Roswell Park CCC, Simmons CCC at University of Texas Southwestern, O’Neal CCC at University of Alabama, Buffett CC at University of Nebraska, Huntsman Cancer Institute, Knight CC at Oregon Health & Science University, Hollings CC at Medical University of South Carolina, and Rutgers Cancer Institute of New Jersey as an external advisory board (EAB) member; personal fees from Mayo Clinic CCC as EAB co-chair; personal fees from Lurie CCC at Northwestern University as ad hoc EAB consultant; personal fees from Guardant Health as advisor on blood-based cancer early detection test development; an institutional grant from Exact Sciences for advice on blood-based cancer early detection test; and grants from National Cancer Institute as advisor for cancer prevention and population sciences and co-advisor for community outreach and engagement and serving as an unpaid advisor on cancer prevention programming for Cancer Prevention and Research Institute of Texas and as the T. Boone Pickens Distinguished Chair for Early Prevention of Cancer, an endowed position that partially supported salary related to projects outside the submitted work. No other disclosures were reported.