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Review
. 2022 Jun 14;14(12):2456.
doi: 10.3390/nu14122456.

How Diet and Physical Activity Modulate Gut Microbiota: Evidence, and Perspectives

Affiliations
Review

How Diet and Physical Activity Modulate Gut Microbiota: Evidence, and Perspectives

Daniela Campaniello et al. Nutrients. .

Abstract

Gut microbiota plays a significant role in the maintenance of physiological homeostasis, contributing to human health. Nevertheless, some factors (sex, age, lifestyle, physical activity, drug-based therapies, diet, etc.) affect its composition and functionality, linked to pathologies and immunological diseases. Concerning diet, it interacts with microorganisms, leading to beneficial or detrimental outcomes for the health of host. On the other hand, physical activity is known to be useful for preventing and, sometimes, treating several diseases of cardiovascular, neuroendocrine, respiratory, and muscular systems. This paper focuses on diet and physical activity presenting the current knowledge about how different diets (Western, ketogenic, vegan, gluten free, Mediterranean) as well as different types of exercise (intensive, endurance, aerobic) could shape gut microbiota.

Keywords: Mediterranean diet; endurance fitness; gut microbiota; ketogenic diet; physical exercise.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Main effects of diets on gut microbiota.
Figure 2
Figure 2
Main effects of physical exercises on gut microbiota.

References

    1. Juárez-Fernández M., Porras D., García-Mediavilla M.V., Román-Sagüillo S., González-Gallego J., Nistal E., Sánchez-Campos S. Aging, Gut Microbiota and Metabolic Diseases: Management through Physical Exercise and Nutritional Interventions. Nutrients. 2021;13:16. doi: 10.3390/nu13010016. - DOI - PMC - PubMed
    1. Marchesi J.R., Ravel J. The vocabulary of microbiome research: A proposal. Microbiome. 2015;3:31. doi: 10.1186/s40168-015-0094-5. - DOI - PMC - PubMed
    1. Mika A., Treuren W.V., González A., Herrera J.J., Knight R., Fleshne M. Exercise is more effective at altering gut microbial composition and producing stable changes in lean mass in juvenile versus adult male F344 rats. PLoS ONE. 2015;10:e0125889. doi: 10.1371/journal.pone.0125889. - DOI - PMC - PubMed
    1. Gasbarrini A., Dionisi T., Gasbarrini G. L’azione del Microbiota nel trapianto fecale. Atti Della Accad. Lancisiana. 2019;63:113–121.
    1. Bibbò S., Ianiro G., Giorgio V., Scaldaferri F., Masucci L., Gasbarrini A., Cammarota G. The role of diet on gut microbiota composition. Eur. Rev. Med. Pharmacol. Sci. 2016;20:4742–4749. - PubMed

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