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. 2021 Apr 30;7(5):352.
doi: 10.3390/jof7050352.

The Current State of Antifungal Stewardship in Immunocompromised Populations

William Alegria  1   2 , Payal K Patel  3   4
Affiliations

The Current State of Antifungal Stewardship in Immunocompromised Populations

William Alegria et al. J Fungi (Basel). .

Abstract

Inappropriate antifungal use is prevalent and can lead to drug-resistant fungi, expose patients to adverse drug events, and increase healthcare costs. While antimicrobial stewardship programs have traditionally focused on antibiotic use, the need for targeted antifungal stewardship (AFS) intervention has garnered interest in recent years. Despite this, data on AFS in immunocompromised patient populations is limited. This paper will review the current state of AFS in this complex population and explore opportunities for multidisciplinary collaboration.

Keywords: antifungal stewardship; immunocompromised; invasive fungal infections.

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Conflict of interest statement

All authors have no conflict of interest or funding source.

Figures

Figure 1
Figure 1
Mycoses Study Group Education and Research Consortium Antifungal Stewardship Core Elements [12].
See this image and copyright information in PMC

References

    1. Barlam T.F., Cosgrove S.E., Abbo L.M., MacDougall C., Schuetz A.N., Septimus E.J., Srinivasan A., Dellit T.H., Falck-Ytter Y.T., Fishman N.O., et al. Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin. Infect. Dis. 2016;62:e51–e77. doi: 10.1093/cid/ciw118. - DOI - PMC - PubMed
    1. Antworth A., Collins C.D., Kunapuli A., Klein K., Carver P., Gandhi T., Washer L., Nagel J.L. Impact of an Antimicrobial Stewardship Program Comprehensive Care Bundle on Management of Candidemia. Pharm. J. Hum. Pharmacol. Drug Ther. 2013;33:137–143. doi: 10.1002/phar.1186. - DOI - PubMed
    1. López-Cortés L.E., Del Toro M.D., Gálvez-Acebal J., Bereciartua-Bastarrica E., Fariñas M.C., Sanz-Franco M., Natera C., Corzo J.E., Lomas J.M., Pasquau J., et al. Impact of an Evidence-Based Bundle Intervention in the Quality-of-Care Management and Outcome of Staphylococcus aureus Bacteremia. Clin. Infect. Dis. 2013;57:1225–1233. doi: 10.1093/cid/cit499. - DOI - PubMed
    1. Pogue J.M., Mynatt R.P., Marchaim D., Zhao J.J., Barr V.O., Moshos J., Sunkara B., Chopra T., Chidurala S., Kaye K.S. Automated Alerts Coupled with Antimicrobial Stewardship Intervention Lead to Decreases in Length of Stay in Patients with Gram-Negative Bacteremia. Infect. Control Hosp. Epidemiol. 2014;35:132–138. doi: 10.1086/674849. - DOI - PubMed
    1. Pollack L.A., Srinivasan A. Core elements of hospital antibiotic stewardship programs from the Centers for Disease Control and Prevention. Clin. Infect. Dis. 2014;59(Suppl. 3):S97–S100. doi: 10.1093/cid/ciu542. - DOI - PMC - PubMed

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