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Review
. 2020:53:e20200013.
doi: 10.1590/0037-8682-0013-2020. Epub 2020 Jun 1.

Human fusariosis: An emerging infection that is difficult to treat

Bruna Gerardon Batista  1 , Magda Antunes de Chaves  2 , Paula Reginatto  1 , Otávio Jaconi Saraiva  3 , Alexandre Meneghello Fuentefria  1   2   3
Affiliations
Review

Human fusariosis: An emerging infection that is difficult to treat

Bruna Gerardon Batista et al. Rev Soc Bras Med Trop. 2020.

Abstract

Fusarium spp. has been associated with a broad spectrum of emerging infections collectively termed fusariosis. This review includes articles published between 2005 and 2018 that describe the characteristics, clinical management, incidence, and emergence of these fungal infections. Fusarium solani and F. oxysporum are globally distributed and represent the most common complexes. Few therapeutic options exist due to intrinsic resistance, especially for the treatment of invasive fusariosis. Therefore, the use of drug combinations could be an important alternative for systemic antifungal resistance. Increase in the number of case reports on invasive fusariosis between 2005 and 2018 is evidence of the emergence of this fungal infection.

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Conflict of interest statement

Conflict of interest: The authors declare no competing interests.

Figures

FIGURE 1
FIGURE 1. (A): Case reports of fusariosis published on the Pubmed Plataform between 2005 and 2018. (B): Case reports of fusariosis published on the Science Direct platform between 2005 and 2018
See this image and copyright information in PMC

References

    1. Gomes LB, Ward TJ, Badiale-Furlong E, Del Ponte EM. Species composition, toxigenic potential and pathogenicity of Fusarium graminearum species complex isolates from southern Brazilian rice. Plant Pathol. 2014;64(4):980–987.
    1. Al-Hatmi AMS, Bonifaz A, Ranques S, de Hoog GS, Verweij PE, Meis JF. Current antifungal treatment of Fusariosis. Int J Antimicrob Agents. 2018;51(3):326–332. - PubMed
    1. Spolti P, Del Ponte EM, Dong Y, Cummings JA, Bergstrom GC. Triazole sensitivity in a contemporary population of Fusarium graminearum from New York wheat and competitiveness of a tebuconazole-resistant isolate. Plant Dis. 2014;98(5):607–613. - PubMed
    1. Dalhoff A. Does the use of antifungal agents in agriculture and food foster polyene resistance development? A reason for concern. J Glob Antimicrob Resist. 2018;13:40–48. - PubMed
    1. Guarro J. Fusariosis, a complex infection caused by a high diversity of fungal species refractory to treatment. Eur J Clin Microbiol Infect Dis. 2013;32(12):1491–1500. - PubMed

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