Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Sep:668 Suppl 1:S70-80.
doi: 10.1016/j.ejphar.2011.07.013. Epub 2011 Jul 27.

Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management

Caroline G M de Theije  1 , Jiangbo Wu, Sofia Lopes da Silva, Patrick J Kamphuis, Johan Garssen, S Mechiel Korte, Aletta D Kraneveld
Affiliations
Review

Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management

Caroline G M de Theije et al. Eur J Pharmacol. 2011 Sep.

Abstract

Autism spectrum disorders (ASDs) are pervasive neurodevelopmental disorders, characterized by impairments in social interaction and communication and the presence of limited, repetitive and stereotyped interests and behavior. Bowel symptoms are frequently reported in children with ASD and a potential role for gastrointestinal disturbances in ASD has been suggested. This review focuses on the importance of (allergic) gastrointestinal problems in ASD. We provide an overview of the possible gut-to-brain pathways and discuss opportunities for pharmaceutical and/or nutritional approaches for therapy.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources