Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Jan 15;297(1-2):137-40.
doi: 10.1016/j.mce.2008.11.018. Epub 2008 Nov 25.

Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue

David Russell-Jones  1
Affiliations
Review

Molecular, pharmacological and clinical aspects of liraglutide, a once-daily human GLP-1 analogue

David Russell-Jones. Mol Cell Endocrinol. .

Abstract

Liraglutide, a human glucagon-like peptide 1 (GLP-1) analogue with high homology to native GLP-1, has structural modifications sufficient to amend pharmacokinetics for once-daily administration without compromising biological activity. Data from large, controlled, clinical studies have confirmed the therapeutic profile of liraglutide, with robust reductions in HbA(1c), low risk of hypoglycaemia and clinically relevant reductions in body weight and systolic blood pressure.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources