MX2019014546A - A peptide with anti-cancer activity and with selectivity to breast cancer cells. - Google Patents

A peptide with anti-cancer activity and with selectivity to breast cancer cells.

Info

Publication number
MX2019014546A
MX2019014546A MX2019014546A MX2019014546A MX2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A
Authority
MX
Mexico
Prior art keywords
peptide
breast cancer
selectivity
cancer cells
activity
Prior art date
Application number
MX2019014546A
Other languages
Spanish (es)
Inventor
Correa Catalina Soriano
Salcedo Carolina Barrientos
CRUZ María Isabel SOTO
Cortés Mercedes Bermúdez
Herrera Martha Legorreta
Original Assignee
Univ Mexico Nac Autonoma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mexico Nac Autonoma filed Critical Univ Mexico Nac Autonoma
Priority to MX2019014546A priority Critical patent/MX2019014546A/en
Priority to PCT/MX2020/050045 priority patent/WO2021112662A1/en
Publication of MX2019014546A publication Critical patent/MX2019014546A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to the design of a novel peptide of the pharmaceutical interest and with application in antitumor therapy in breast cancer cells. Said peptide has a hexa-peptide structure corresponding to a sequence of six amino acids repeated five times (FSKWLL). Also, it aims to form part of the therapeutic schemes used in breast cancer, particularly in those tumors that do not show expression of the extracellular domain of the EGFR protein, which is the target of the drug Herceptin. Further, it may be useful after resection and before starting chemotherapy.
MX2019014546A 2019-12-04 2019-12-04 A peptide with anti-cancer activity and with selectivity to breast cancer cells. MX2019014546A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MX2019014546A MX2019014546A (en) 2019-12-04 2019-12-04 A peptide with anti-cancer activity and with selectivity to breast cancer cells.
PCT/MX2020/050045 WO2021112662A1 (en) 2019-12-04 2020-11-24 Peptide with anticancer activity against breast cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2019014546A MX2019014546A (en) 2019-12-04 2019-12-04 A peptide with anti-cancer activity and with selectivity to breast cancer cells.

Publications (1)

Publication Number Publication Date
MX2019014546A true MX2019014546A (en) 2023-01-10

Family

ID=76222632

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019014546A MX2019014546A (en) 2019-12-04 2019-12-04 A peptide with anti-cancer activity and with selectivity to breast cancer cells.

Country Status (2)

Country Link
MX (1) MX2019014546A (en)
WO (1) WO2021112662A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020046793A1 (en) 2018-08-27 2020-03-05 Regeneron Pharmaceuticals, Inc. Use of raman spectroscopy in downstream purification

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017013613A (en) * 2015-04-23 2018-09-12 Nantomics Llc CANCER NEOEPITODES.

Also Published As

Publication number Publication date
WO2021112662A1 (en) 2021-06-10

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