MX2019014546A - A peptide with anti-cancer activity and with selectivity to breast cancer cells. - Google Patents
A peptide with anti-cancer activity and with selectivity to breast cancer cells.Info
- Publication number
- MX2019014546A MX2019014546A MX2019014546A MX2019014546A MX2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A MX 2019014546 A MX2019014546 A MX 2019014546A
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- breast cancer
- selectivity
- cancer cells
- activity
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 3
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 230000001093 anti-cancer Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 abstract 1
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 abstract 1
- 229940022353 herceptin Drugs 0.000 abstract 1
- 238000002271 resection Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention relates to the design of a novel peptide of the pharmaceutical interest and with application in antitumor therapy in breast cancer cells. Said peptide has a hexa-peptide structure corresponding to a sequence of six amino acids repeated five times (FSKWLL). Also, it aims to form part of the therapeutic schemes used in breast cancer, particularly in those tumors that do not show expression of the extracellular domain of the EGFR protein, which is the target of the drug Herceptin. Further, it may be useful after resection and before starting chemotherapy.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2019014546A MX2019014546A (en) | 2019-12-04 | 2019-12-04 | A peptide with anti-cancer activity and with selectivity to breast cancer cells. |
| PCT/MX2020/050045 WO2021112662A1 (en) | 2019-12-04 | 2020-11-24 | Peptide with anticancer activity against breast cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2019014546A MX2019014546A (en) | 2019-12-04 | 2019-12-04 | A peptide with anti-cancer activity and with selectivity to breast cancer cells. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019014546A true MX2019014546A (en) | 2023-01-10 |
Family
ID=76222632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019014546A MX2019014546A (en) | 2019-12-04 | 2019-12-04 | A peptide with anti-cancer activity and with selectivity to breast cancer cells. |
Country Status (2)
| Country | Link |
|---|---|
| MX (1) | MX2019014546A (en) |
| WO (1) | WO2021112662A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020046793A1 (en) | 2018-08-27 | 2020-03-05 | Regeneron Pharmaceuticals, Inc. | Use of raman spectroscopy in downstream purification |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017013613A (en) * | 2015-04-23 | 2018-09-12 | Nantomics Llc | CANCER NEOEPITODES. |
-
2019
- 2019-12-04 MX MX2019014546A patent/MX2019014546A/en unknown
-
2020
- 2020-11-24 WO PCT/MX2020/050045 patent/WO2021112662A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021112662A1 (en) | 2021-06-10 |
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