FR23C1036I1 - Anticorps qui se lient à il-23 - Google Patents

Anticorps qui se lient à il-23

Info

Publication number
FR23C1036I1
FR23C1036I1 FR23C1036C FR23C1036C FR23C1036I1 FR 23C1036 I1 FR23C1036 I1 FR 23C1036I1 FR 23C1036 C FR23C1036 C FR 23C1036C FR 23C1036 C FR23C1036 C FR 23C1036C FR 23C1036 I1 FR23C1036 I1 FR 23C1036I1
Authority
FR
France
Prior art keywords
antibodies
bind
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR23C1036C
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR23C1036I1 publication Critical patent/FR23C1036I1/fr
Application granted granted Critical
Publication of FR23C1036I2 publication Critical patent/FR23C1036I2/fr
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR23C1036C 2013-03-08 2023-10-13 Anticorps qui se lient à il-23 Active FR23C1036I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361774732P 2013-03-08 2013-03-08
PCT/US2014/020064 WO2014137962A1 (fr) 2013-03-08 2014-03-04 Anticorps qui se lient à il-23

Publications (2)

Publication Number Publication Date
FR23C1036I1 true FR23C1036I1 (fr) 2023-12-08
FR23C1036I2 FR23C1036I2 (fr) 2024-10-04

Family

ID=51488096

Family Applications (1)

Application Number Title Priority Date Filing Date
FR23C1036C Active FR23C1036I2 (fr) 2013-03-08 2023-10-13 Anticorps qui se lient à il-23

Country Status (40)

Country Link
US (3) US9023358B2 (fr)
EP (3) EP2964258B1 (fr)
JP (1) JP6096938B2 (fr)
KR (2) KR20170103037A (fr)
CN (1) CN105307681B (fr)
AP (1) AP2015008708A0 (fr)
AR (1) AR094877A1 (fr)
AU (1) AU2014226094C1 (fr)
BR (1) BR112015019611B1 (fr)
CA (1) CA2901462C (fr)
CL (1) CL2015002388A1 (fr)
CY (2) CY1123589T1 (fr)
DK (1) DK2964258T3 (fr)
EA (1) EA031524B1 (fr)
EC (1) ECSP15038626A (fr)
ES (1) ES2822662T3 (fr)
FI (1) FIC20230030I1 (fr)
FR (1) FR23C1036I2 (fr)
HR (1) HRP20201633T1 (fr)
HU (2) HUE051357T2 (fr)
IL (2) IL240731B (fr)
JO (1) JOP20140049B1 (fr)
LT (2) LT2964258T (fr)
MA (1) MA38382A1 (fr)
MX (1) MX370396B (fr)
MY (1) MY171226A (fr)
NL (1) NL301247I2 (fr)
NO (1) NO2023037I1 (fr)
PE (1) PE20151529A1 (fr)
PH (1) PH12015501994B1 (fr)
PL (1) PL2964258T3 (fr)
PT (1) PT2964258T (fr)
RS (1) RS60928B1 (fr)
SG (1) SG11201507176VA (fr)
SI (1) SI2964258T1 (fr)
TN (1) TN2015000348A1 (fr)
TW (1) TWI636063B (fr)
UA (1) UA123198C2 (fr)
WO (1) WO2014137962A1 (fr)
ZA (1) ZA201505285B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR102417A1 (es) * 2014-11-05 2017-03-01 Lilly Co Eli Anticuerpos biespecíficos anti-tnf- / anti-il-23
US20180291093A1 (en) * 2015-10-30 2018-10-11 Eli Lilly And Company Anti-cgrp/anti-il-23 bispecific antibodies and uses thereof
AR111845A1 (es) 2017-05-03 2019-08-28 Lilly Co Eli Anticuerpos biespecíficos anti-cgrp / anti-il-23 y usos de los mismos
TWI744617B (zh) 2018-03-30 2021-11-01 美商美國禮來大藥廠 治療潰瘍性結腸炎之方法
TWI725532B (zh) 2018-09-11 2021-04-21 美商美國禮來大藥廠 治療牛皮癬之方法
TWI850365B (zh) 2019-04-22 2024-08-01 美商美國禮來大藥廠 治療克隆氏症(crohn's disease)的方法
KR20220054689A (ko) 2019-10-15 2022-05-03 일라이 릴리 앤드 캄파니 재조합적으로 조작된, 리파제/에스테라제-결핍 포유동물 세포주
CA3164996A1 (fr) 2019-12-20 2021-06-14 Novarock Biotherapeutics, Ltd. Anticorps anti-interleukine-23 p19 et leurs methodes d'utilisation
CN112807428B (zh) * 2020-06-12 2024-08-27 江苏荃信生物医药股份有限公司 包含抗人白介素23单克隆抗体的药物组合物
WO2022041390A1 (fr) * 2020-08-28 2022-03-03 江苏荃信生物医药股份有限公司 Formulation liquide à faible viscosité comprenant un anticorps monoclonal anti-interleukine 23 humaine à concentration élevée, et son procédé de préparation
AR123477A1 (es) 2020-09-10 2022-12-07 Lilly Co Eli Formulaciones de anticuerpos terapéuticos
US20240254217A1 (en) 2021-05-28 2024-08-01 Eli Lilly And Company Anti -il-23p19 antibody regulation of genes involved in ulcerative colitis
CN113698480B (zh) * 2021-09-18 2022-07-01 东大生物技术(苏州)有限公司 一组il-23单克隆抗体及其医药用途
US20240391994A1 (en) 2021-09-30 2024-11-28 Eli Lilly And Company Anti-il-23p19 antibody regulation of genes involved in bowel urgency in ulcerative colitis
WO2024077113A1 (fr) 2022-10-06 2024-04-11 Eli Lilly And Company Méthodes de traitement de la fatigue liée à la colite ulcéreuse
CN120882881A (zh) 2023-02-22 2025-10-31 伊莱利利公司 溃疡性结肠炎的基因调控及其用途
AU2024236477A1 (en) 2023-03-10 2025-09-11 Eli Lilly And Company Methods of treating ulcerative colitis
WO2025083549A1 (fr) 2023-10-16 2025-04-24 Sun Pharma Advanced Research Company Limited Méthodes et combinaisons d'inhibiteurs de la voie il-23 et de modulateurs de la voie de signalisation s1p pour le traitement de maladies auto-immunes
WO2025117506A1 (fr) 2023-11-29 2025-06-05 Gilead Sciences, Inc. Traitement des maladies inflammatoires chroniques de l'intestin

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060284A (en) 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
US7282204B2 (en) 2003-03-10 2007-10-16 Schering Corporation Uses of IL-23 agonists and antagonists; related reagents
US8003108B2 (en) * 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
SI2452694T1 (sl) 2005-06-30 2019-05-31 Janssen Biotech, Inc. Protitelesa proti-IL-23, sestavki in postopki uporabe
CN101248088A (zh) * 2005-08-25 2008-08-20 伊莱利利公司 抗il-23抗体
DK1937721T3 (da) * 2005-08-25 2010-10-18 Lilly Co Eli Anti-IL-23 antistoffer
LT1931710T (lt) * 2005-08-31 2017-03-27 Merck Sharp & Dohme Corp. Rekombinantiniai anti-il-23 antikūnai
LT2548577T (lt) * 2005-12-29 2017-04-10 Janssen Biotech, Inc. Žmogaus anti-il-23 antikūnai, kompozicijos, būdai ir panaudojimai
MX2009009080A (es) * 2007-02-23 2009-11-02 Schering Corp Anticuerpos anti-interleucina-23p19 manipulados por ingenieria genetica.
LT2426144T (lt) 2007-02-23 2018-12-10 Merck Sharp & Dohme Corp. Genų inžinerijos būdu pagaminti anti-il-23p19 antikūnai
SI2131860T1 (sl) * 2007-03-20 2014-02-28 Eli Lilly And Company Protitelesa proti sklerostinu
WO2008141044A2 (fr) 2007-05-08 2008-11-20 Genentech, Inc. Anticorps anti-muc16 produits avec de la cystéine et conjugués anticorps-médicament
WO2009082624A2 (fr) * 2007-12-10 2009-07-02 Zymogenetics, Inc. Antagonistes de il-17a, il-17f et il-23 et procédés d'utilisation de ceux-ci
EP2435480A1 (fr) * 2009-05-27 2012-04-04 Ablynx N.V. Produits de construction protéiques biparatopiques dirigés contre il-23
ES2593754T3 (es) * 2010-11-04 2016-12-13 Boehringer Ingelheim International Gmbh Anticuerpos anti-IL-23
CA2833212C (fr) * 2011-05-12 2020-06-09 Genentech, Inc. Reaction multiple de surveillance du procede lc-ms/ms pour detecter les anticorps therapeutiques dans les echantillons d'animaux par des peptides de signature du cadre

Also Published As

Publication number Publication date
EP4311558A3 (fr) 2024-04-10
PE20151529A1 (es) 2015-10-28
PH12015501994B1 (en) 2023-03-01
JP6096938B2 (ja) 2017-03-15
HRP20201633T1 (hr) 2020-12-25
MA38382A1 (fr) 2017-11-30
PH12015501994A1 (en) 2016-01-11
AU2014226094B2 (en) 2016-06-23
TWI636063B (zh) 2018-09-21
TN2015000348A1 (en) 2017-01-03
IL272042A (en) 2020-02-27
AP2015008708A0 (en) 2015-09-30
SI2964258T1 (sl) 2020-10-30
US20150232552A1 (en) 2015-08-20
TW201520225A (zh) 2015-06-01
BR112015019611B1 (pt) 2023-05-02
ZA201505285B (en) 2017-11-29
UA123198C2 (uk) 2021-03-03
NL301247I1 (nl) 2023-10-11
HK1212252A1 (en) 2016-06-10
HUS2300036I1 (hu) 2024-07-28
IL272042B (en) 2021-07-29
US9688753B2 (en) 2017-06-27
DK2964258T3 (da) 2020-09-14
LTPA2023530I1 (fr) 2023-11-10
KR20150113202A (ko) 2015-10-07
IL240731B (en) 2020-01-30
CN105307681A (zh) 2016-02-03
NO2023037I1 (no) 2023-10-04
SG11201507176VA (en) 2015-10-29
AU2014226094A1 (en) 2015-08-27
JP2016510744A (ja) 2016-04-11
RS60928B1 (sr) 2020-11-30
CA2901462C (fr) 2017-07-25
NL301247I2 (nl) 2023-11-01
WO2014137962A1 (fr) 2014-09-12
CY1123589T1 (el) 2022-03-24
CY2023021I2 (el) 2024-09-20
LT2964258T (lt) 2020-10-12
IL240731A0 (en) 2015-10-29
EP4311558A2 (fr) 2024-01-31
AR094877A1 (es) 2015-09-02
HUE051357T2 (hu) 2021-03-01
US20140255422A1 (en) 2014-09-11
MX370396B (es) 2019-12-11
FIC20230030I1 (fi) 2023-10-03
FR23C1036I2 (fr) 2024-10-04
EP3789037A1 (fr) 2021-03-10
LTC2964258I2 (fr) 2025-09-10
MX2015011959A (es) 2016-04-07
CY2023021I1 (el) 2024-02-16
KR101775115B1 (ko) 2017-09-05
US9023358B2 (en) 2015-05-05
EP2964258B1 (fr) 2020-09-02
CN105307681B (zh) 2018-06-26
ECSP15038626A (es) 2015-11-30
EP2964258A4 (fr) 2016-10-12
US20170275356A1 (en) 2017-09-28
EA201591368A1 (ru) 2015-12-30
AU2014226094C1 (en) 2024-10-24
PL2964258T3 (pl) 2021-02-08
BR112015019611A2 (pt) 2017-08-22
MY171226A (en) 2019-10-03
NZ711147A (en) 2021-03-26
EA031524B1 (ru) 2019-01-31
CA2901462A1 (fr) 2014-09-12
JOP20140049B1 (ar) 2021-08-17
PT2964258T (pt) 2020-11-06
CL2015002388A1 (es) 2016-03-04
ES2822662T3 (es) 2021-05-04
EP2964258A1 (fr) 2016-01-13
KR20170103037A (ko) 2017-09-12

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