CN108094403A - Isolated organ perfusion container - Google Patents

Abstract

The present invention relates to a kind of isolated organ perfusion containers, including chassis, support plate, connect drain cap and upper cover.Chassis includes bottom plate and side plate, and side plate is disposed around the surrounding of bottom plate.Support plate is mounted on side plate.Mounting hole is provided in support plate.It connects drain cap installation on the supporting plate, and connects drain cap and be located in mounting hole.The bottom for connecing drain cap is provided with leakage hole.Upper cover lid is set on the supporting plate.Intrusion pipe is offered on chassis and goes out pore into pore and intrusion pipe.It is provided in support plate intermediate into pore.Above-mentioned isolated organ perfusion container can make intrusion pipe cabling smooth, perfusion effect be improved, so as to extend the preservation duration of isolated organ.

Description

Isolated Organ Perfusion Containers

technical field

The invention relates to the field of medical instruments, in particular to an isolated organ perfusion container.

Background technique

As the demand for donors increased, some "marginal donors" who did not meet the requirements before were also used. Marginal donors refer to elderly donors or donors after cardiac death (Donation after Cardiac Death, DCD). DCD donor organs are of poor quality, and cryopreservation will further aggravate the damage, while normal temperature perfusion can be used to preserve the organs in vitro to maintain normal physiological functions and reduce damage to a greater extent. Normal temperature perfusion is a relatively complicated process. In the existing normal temperature perfusion system, the alignment of the perfusion tube in the container placed in the isolated organ is relatively messy, which makes the perfusate in the perfusion tube not flow smoothly, and even the perfusate backflow occurs, affecting The effect of perfusion, resulting in the length of organ preservation.

Contents of the invention

Based on this, it is necessary to address the problem of the length of organ preservation and provide an isolated organ perfusion container, which can prolong the preservation period of the isolated organ.

An isolated organ perfusion container, comprising a chassis, a support plate, a leak tray and an upper cover; the chassis includes a bottom plate and side plates, and the side plates are arranged around the bottom plate; the support plate is installed on the On the side plate, there is an installation hole on the support plate; the leak tray is installed on the support plate, and the leak tray is located in the installation hole, and the bottom of the leak tray has a Leak hole; the upper cover is set on the support plate; the chassis is provided with a perfusion pipe inlet hole and a perfusion pipe outlet hole, and an intermediate pipe inlet hole is opened on the support plate.

The above-mentioned isolated organ perfusion container and the leak tray are used for placing the organ. When organ perfusion is performed, the organ is placed in the leak tray; the venous perfusion inlet tube and the arterial perfusion inlet tube are threaded from the perfusion tube inlet hole into the chassis, and then passed upward through the middle inlet hole on the support plate; then The intravenous perfusion inlet tube and the arterial perfusion fluid inlet tube are respectively connected to one end of the organ vein and one end of the organ artery; the other end of the vein is connected to the vein perfusion outlet tube, and the other end of the artery is connected to the arterial perfusion outlet tube, and then the The venous perfusion outlet tubing and the arterial perfusion outlet tubing pass down through the leak hole into the chassis, and finally out of the chassis through the perfusion tubing outlet hole. The support plate is installed on the side plate of the chassis, so the height of the inlet pipe hole in the middle will be higher than the outlet pipe hole of the perfusion pipe, and the perfusate that has entered the organ will not flow back to the perfusion inlet pipe, but will be discharged under the action of gravity. It flows out along the perfusion outlet tube, thereby increasing the smoothness of perfusate perfusion. Therefore, the above-mentioned isolated organ perfusion container can make the perfusion tube run smoothly, improve the perfusion effect, and prolong the storage time of the isolated organ.

In addition, the setting of the upper cover can make the organ perfuse in a relatively closed environment, reduce the influence of the external environment, prolong the storage time of the organ, and the opening and closing of the upper cover will not affect the use of the perfusion tube. Moreover, the isolated organ perfusion container has a simple structure, and can conveniently carry and transport the isolated organ.

In one of the embodiments, an adjustment frame is provided on the support plate, the adjustment frame is rotatably mounted on the support plate, and the adjustment frame can be rotated above the opening of the leak tray; The adjustment frame is provided with strip holes, and the walls of the strip holes are sequentially provided with a plurality of slots for clamping the perfusion tube. In this way, after the intravenous perfusion liquid inlet pipe and the arterial perfusion liquid inlet pipe pass through the middle pipe inlet hole on the support plate, the intravenous perfusion liquid inlet pipe and the arterial perfusion liquid inlet pipe are passed through the strip holes on the adjustment frame, They are then connected to veins and arteries, respectively. The adjustment frame is rotatably installed on the bracket plate and can be rotated to the top of the mouth of the leakage tray, so that the adjustment frame can be rotated according to the actual situation, or the card slot that clamps the perfusion tube can be replaced to adjust the intravenous perfusion inlet tube and The position of the arterial perfusion inlet tube makes the perfusate flow smoothly and improves the perfusion effect. The card slot can clamp the venous infusion tube and the arterial infusion tube to keep them stable.

In one of the embodiments, a support plate is provided in the leak tray, and a plurality of openings are opened on the support plate; a distance is provided between the support plate and the bottom of the leak tray. Venous infusion and arterial infusion outlets pass through the ostium. The support plate is used to store the isolated organs, and separates the isolated organs from the bottom of the drain tray. By opening holes, the direct contact area between the isolated organs and the container is reduced, thereby reducing damage to the isolated organs. In addition, the waste liquid produced by the organ can fall downward through the opening, thereby reducing the damage of the waste liquid to the isolated organ.

In one of the embodiments, the inner wall of the leak tray is provided with a plurality of connection protrusions, the connection protrusions are provided with first positioning holes, and the support plate is provided with a first positioning block. The first positioning block engages with the first positioning hole. Match the first positioning block to the first positioning hole, press the first positioning block into the first positioning hole to complete the installation of the pallet, pull out the pallet at the opening to remove the pallet, so very It is convenient for the installation and routing of the venous perfusion outlet tube and the arterial perfusion outlet tube.

In one of the embodiments, an installation boss is provided on the outer side of the mouth of the leak tray, and the leak tray overlaps the support plate through the installation boss.

In one of the embodiments, the supporting plate is provided with positioning protruding belts, the positioning protruding belts are arranged along the edge of the supporting plate, and the positioning protruding belts protrude from both sides of the supporting plate The inner side of the positioning protruding belt on one side of the support plate is in clearance fit with the side plate of the chassis, and the inner side of the positioning protruding belt on the other side of the support plate is in clearance fit with the upper cover. The setting of the positioning convex belt can facilitate the assembly and positioning among the chassis, the support plate and the upper cover, and complete the assembly quickly.

In one of the embodiments, the bottom plate of the chassis is provided with a plurality of reinforcing ribs, and the reinforcing ribs intersect to form at least one second positioning hole, and the bottom of the leakage tray is provided with a second positioning block, and the second The positioning block is engaged with the second positioning hole. The setting of the reinforcing rib can strengthen the stress strength of the chassis and improve the durability of the chassis; the second positioning hole and the second positioning block are snapped together so that the leak tray is supported on the rib, which can improve the durability of the leak tray. The load-bearing capacity and the stability of the leak pan installation, so that it will not affect the filling work.

In one of the embodiments, the chassis is a square plate; the side plate includes a first side wall, a second side wall, a third side wall and a fourth side wall, and the first side wall and the third side wall The side walls are arranged oppositely, the second side wall is arranged opposite to the fourth side wall; the middle part of the first side wall is provided with a first groove recessed into the chassis, and the third side wall The two sides of the two sides are provided with the second groove recessed into the chassis; the bottom wall of the first groove is provided with at least two outlet holes of the perfusion pipe, and the two second grooves are The bottom wall is provided with an auxiliary hole and a pipe inlet hole for the perfusion pipe, and a pipe inlet hole for the perfusion pipe is respectively provided on the second side wall and the fourth side wall, and the perfusion pipe inlet hole is close to The third side wall is set; the second side wall and the fourth side wall are provided with sensor installation grooves; the support plate is provided with two middle inlet pipe holes, and the two middle inlet holes The pipe holes are located on both sides of the installation hole, and the middle pipe inlet hole is set close to the third side wall; the bottom of the leak tray is provided with three leak holes.

In one of the embodiments, the isolated organ perfusion container is a fully transparent container. In this way, the situation inside the container can be observed from the outside.

Description of drawings

Fig. 1 is a schematic diagram of the external structure of the isolated organ perfusion container according to the embodiment of the present invention;

Fig. 2 is a schematic structural view of the isolated organ perfusion container according to the embodiment of the present invention after opening the upper cover;

Fig. 3 is a schematic structural view of the chassis of the isolated organ perfusion container according to the embodiment of the present invention;

Fig. 4 is a schematic structural view of the support plate in the isolated organ perfusion container according to the embodiment of the present invention;

Fig. 5 is a structural schematic diagram of a certain angle of the leakage tray in the isolated organ perfusion container according to the embodiment of the present invention;

Fig. 6 is a structural schematic diagram of another angle of the leakage tray in the isolated organ perfusion container according to the embodiment of the present invention;

Fig. 7 is a schematic structural view of the support plate in the isolated organ perfusion container according to the embodiment of the present invention.

100, chassis, 110, bottom plate, 111, reinforcing rib, 112, second positioning hole, 120, side plate, 121, first side wall, 122, second side wall, 123, third side wall, 124, fourth Side wall, 125, first groove, 126, second groove, 127, auxiliary hole, 128, sensor installation groove, 130, perfusion tube inlet hole, 140, perfusion tube outlet hole, 200, support plate, 210 , installation hole, 220, middle pipe inlet hole, 230, positioning convex belt, 300, leak plate, 310, leakage hole, 320, connection protrusion, 321, first positioning hole, 330, installation boss, 340, the first Two positioning blocks, 400, upper cover, 410, handle, 500, adjusting frame, 510, strip hole, 520, draw-in groove, 600, supporting plate, 610, opening, 620, the first positioning block.

Detailed ways

In order to facilitate the understanding of the present invention, the present invention will be described more fully below with reference to the associated drawings. Preferred embodiments of the invention are shown in the accompanying drawings. However, the present invention can be embodied in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present invention more thorough and comprehensive.

It should be noted that when an element is considered to be "connected" to another element, it may be directly connected to the other element or there may be intervening elements at the same time. In contrast, when an element is referred to as being "directly on" another element, there are no intervening elements present. The terms "first", "second", "third" and "fourth" used in this article do not represent the specific quantity and order, but are only used to distinguish the names

As shown in FIGS. 1 to 5 , an isolated organ perfusion container includes a base plate 100 , a support plate 200 , a drain tray 300 and an upper cover 400 . The chassis 100 includes a bottom plate 110 and a side plate 120 , and the side plate 120 surrounds the bottom plate 110 . The support plate 200 is installed on the side plate 120 . A mounting hole 210 is opened on the supporting board 200 . The leak tray 300 is installed on the support plate 200 , and the leak tray 300 is located in the installation hole 210 . A leak hole 310 is opened at the bottom of the leak tray 300 . The upper cover 400 is disposed on the supporting board 200 . The chassis 100 is provided with a perfusion tube inlet hole 130 and a perfusion tube outlet hole 140 . The support plate 200 is provided with a middle pipe inlet hole 220 .

The above-mentioned isolated organ perfusion container, the leak tray 300 is used to place the organ. When organ perfusion is performed, the organ is placed in the leak tray 300 . The venous perfusion liquid inlet tube and the arterial perfusion liquid inlet tube are passed through the perfusion tube inlet hole 130 into the chassis 100 , and then passed upwardly through the middle tube inlet hole 220 on the support plate 200 . Then connect the intravenous perfusion inlet tube and the arterial perfusion fluid inlet tube to one end of the organ vein and one end of the organ artery respectively; The venous and arterial perfusion outlet lines are then passed down through the leak hole 310 and into the chassis 100 . Finally, the chassis 100 is passed through the outlet hole 140 of the perfusion tube. The support plate 200 is installed on the side plate 120 of the chassis 100, then, the height of the middle inlet pipe hole 220 will be higher than the perfusion pipe outlet hole 140, and the perfusate that has entered the organ will not flow back to the perfusion inlet pipe. It flows out along the perfusion outlet pipe under the action of gravity, thereby increasing the smoothness of perfusate perfusion. Therefore, the above-mentioned isolated organ perfusion container can make the perfusion tube run smoothly, improve the perfusion effect, and prolong the storage time of the isolated organ.

As shown in Figure 2, during perfusion, a circulating pump is connected between the intravenous perfusion inlet tube and the intravenous perfusion outlet tube, and a circulation pump is connected between the arterial perfusion inlet tube and the arterial perfusion outlet tube to drive the perfusion fluid. cycle. The dotted line in Fig. 2 represents the schematic line of the blocked perfusion tube.

In addition, the setting of the upper cover 400 can allow the organ to be perfused in a relatively closed environment, reduce the influence of the external environment, and prolong the storage period of the organ. And the opening and closing of the upper cover 400 will not affect the use of each perfusion tube. Moreover, the isolated organ perfusion container has a simple structure, and can conveniently carry and transport the isolated organ.

Wherein, as shown in FIG. 5 and FIG. 6 , the leak tray 300 is preferably in the shape of a round bucket. This can leave installation space for the wiring of the perfusion pipe. A recessed handle 410 is provided on the side of the upper cover 400 to facilitate the opening and closing of the upper cover 400 .

Further, as shown in FIG. 2 , an adjustment frame 500 is provided on the support plate 200 . The adjusting frame 500 is rotatably installed on the support plate 200 , and the adjusting frame 500 can be rotated above the opening of the leak tray 300 . The adjusting frame 500 is provided with a bar-shaped hole 510 . The wall of the strip hole 510 is sequentially provided with a plurality of locking grooves 520 for locking the perfusion tube. In this way, after the intravenous perfusion inlet tube and the arterial perfusion inlet tube pass through the middle inlet hole 220 on the support plate 200, the intravenous perfusion inlet tube and the arterial perfusion inlet tube are passed through the strip hole 510 on the adjustment frame 500. It passes through the middle and connects with veins and arteries respectively. The adjustment frame 500 is rotatably installed on the support plate and can be rotated to the top of the mouth of the leakage tray 300, so that the adjustment frame 500 can be rotated according to the actual situation, or the card slot 520 that clamps the perfusion tube can be replaced to adjust the intravenous perfusion The position of the liquid inlet pipe and the arterial perfusion liquid inlet pipe makes the perfusate flow smoothly and improves the perfusion effect. The clamping groove 520 can tighten the venous perfusion liquid inlet tube and the arterial perfusion liquid inlet tube to keep them stable.

Preferably, four adjustment frames 500 are provided on the supporting board 200 . Four adjusting frames 500 are arranged in sequence around the installation hole 210 . In this way, different adjustment frames 500 can be used according to actual conditions.

Further, as shown in FIG. 2 , a support plate 600 is provided in the leak tray 300 . A plurality of openings 610 are formed on the supporting plate 600 . There is a distance between the supporting plate 600 and the bottom of the leak tray 300 . The venous and arterial perfusion outlet lines pass through the opening 610 . The supporting plate 600 is used to place the isolated organs, and separates the isolated organs from the bottom of the drain tray 300; the setting of the opening 610 can reduce the direct contact area between the isolated organs and the container, thereby reducing the impact on the isolated organs. damage to organs. In addition, the waste liquid produced by the organ can fall downward through the opening 610, thereby reducing the damage of the waste liquid to the isolated organ. Preferably, the opening 610 is an elongated opening 610 .

Specifically, as shown in FIG. 5 and FIG. 7 . A plurality of connection protrusions 320 are provided on the inner wall of the leak tray 300 . A first positioning hole 321 is formed on the connecting protrusion 320 . A first positioning block 620 is formed on the supporting plate 600 . The first positioning block 620 engages with the first positioning hole 321 . Correspond the first positioning block 620 to the first positioning hole 321, press the first positioning block 620 into the first positioning hole 321 to complete the installation of the supporting plate 600, and pull out the supporting plate 600 at the opening 610 to remove it. The supporting plate 600 is removed, which is very convenient for the installation and wiring of the intravenous perfusion outlet tube and the arterial perfusion outlet tube.

Specifically, as shown in FIG. 2 , FIG. 5 and FIG. 6 , a mounting boss 330 is provided on the outside of the drain tray 300 . The leak tray 300 is overlapped on the support plate 200 through the installation boss 330 . In this way, the leak tray 300 can be directly overlapped on the support plate 200 through the installation boss 330, and the installation is convenient and fast. Preferably, the installation boss 330 is an annular installation boss 330 to improve the load-bearing strength of the leak tray 300 .

Further, as shown in FIG. 1 , FIG. 2 and FIG. 4 , the supporting plate 200 is provided with a positioning protruding belt 230 . The positioning protrusions 230 are disposed along the edge of the support plate 200 , and the positioning protrusions 230 protrude from both sides of the support plate 200 . The inner side of the positioning protruding belt 230 on one side of the support plate 200 is in clearance fit with the side plate 120 of the chassis 100 , and the inner side of the positioning protruding belt 230 on the other side of the support plate 200 is in clearance fit with the upper cover 400 . The setting of the positioning protruding belt 230 can facilitate the assembly and positioning among the chassis 100 , the support plate 200 and the upper cover 400 , and complete the assembly quickly.

Further, as shown in FIG. 3 , the bottom plate 110 of the chassis 100 is provided with a plurality of reinforcing ribs 111 . The reinforcing ribs 111 intersect to form at least one second positioning hole 112 . The bottom of the leak tray 300 is provided with a second positioning block 340 . The second positioning block 340 engages with the second positioning hole 112 . The arrangement of the ribs 111 can strengthen the stress strength of the chassis 100 and improve the durability of the chassis 100 . The snap fit between the second positioning hole 112 and the second positioning block 340 enables the leak tray 300 to be supported on the reinforcement rib 111, which can improve the load-bearing capacity of the leak tray 300 and the stability of the installation of the leak tray 300, thereby It will not affect the perfusion work.

Specifically, as shown in FIG. 3 , the bottom plate 110 of the chassis 100 is provided with two sets of reinforcing ribs 111 . A set of reinforcing ribs 111 includes four reinforcing ribs 111 . Four reinforcing ribs 111 are arranged in parallel in pairs, and two parallel reinforcing ribs 111 intersect with the other two parallel reinforcing ribs 111 to form a square second positioning hole 112 , and the second positioning block 340 is correspondingly a square block. In this way, the rotation of the leak tray 300 can be limited.

Specifically, as shown in FIGS. 1 to 4 , the chassis 100 is a square plate. The side panel 120 includes a first side wall 121 , a second side wall 122 , a third side wall 123 and a fourth side wall 124 . The first sidewall 121 is opposite to the third sidewall 123 . The second sidewall 122 is opposite to the fourth sidewall 124 . A central portion of the first sidewall 121 defines a first groove 125 recessed into the chassis 100 . Two sides of the third sidewall 123 define second grooves 126 recessed into the chassis 100 . The bottom wall of the first groove 125 is provided with at least two perfusion tube outlet holes 140 . The bottom walls of the two second grooves 126 are provided with auxiliary holes 127 and a filling tube inlet hole 130 . The second side wall 122 and the fourth side wall 124 are respectively provided with a filling tube inlet hole 130 . The perfusion tube inlet hole 130 is disposed close to the third side wall 123 . The second side wall 122 and the fourth side wall 124 define a sensor installation groove 128 . The support plate 200 is provided with two middle pipe inlet holes 220 , the two middle pipe inlet holes 220 are located on two sides of the installation hole 210 , and the middle pipe inlet holes 220 are disposed near the third side wall 123 . The bottom of the leak tray 300 is provided with three leak holes 310 . The arrangement of the first groove 125 and the second groove 126 can facilitate the handling of the entire container. In a preferred mode of use, the perfusion tube inlet hole 130 on the second side wall 122, the middle inlet hole 220 near the second side wall 122, the leakage hole 310 near the second side wall 122 and the second side wall 122 The perfusion tube outlet hole 140 is provided for the perfusion tube perfusing the vein to pass through. The perfusion tube inlet hole 130 on the fourth side wall 124, the middle tube inlet hole 220 near the fourth side wall 124, the leakage hole 310 near the fourth side wall 124, and the perfusion tube outlet hole near the fourth side wall 124 140 is passed for the perfusion tube that perfuses the artery. In addition, the auxiliary hole 127 and the last leak hole 310 are used for the pipelines of other auxiliary instruments to pass through and connect to the isolated organ. Such pipelines are routed smoothly without intersecting with each other, and the perfusion effect is good, thereby prolonging the preservation period of isolated organs.

Further, the isolated organ perfusion container is a fully transparent container. In this way, the situation inside the container can be observed from the outside.

The technical features of the above-mentioned embodiments can be combined arbitrarily. To make the description concise, all possible combinations of the technical features in the above-mentioned embodiments are not described. However, as long as there is no contradiction in the combination of these technical features, should be considered as within the scope of this specification.

The above-mentioned embodiments only express several implementation modes of the present invention, and the descriptions thereof are relatively specific and detailed, but should not be construed as limiting the patent scope of the invention. It should be pointed out that those skilled in the art can make several modifications and improvements without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent for the present invention should be based on the appended claims.

Claims (9)

1. a kind of isolated organ perfusion container, which is characterized in that including chassis, support plate, connect drain cap and upper cover；The chassis bag Bottom plate and side plate are included, the side plate is disposed around the surrounding of the bottom plate；The support plate is mounted on the side plate, the support Mounting hole is provided on plate；The drain cap that connects is in the support plate, and the drain cap that connects is located in the mounting hole, described The bottom for connecing drain cap is provided with leakage hole；The upper cover lid is located in the support plate；Intrusion pipe is offered on the chassis into pore Go out pore with intrusion pipe, be provided in the support plate intermediate into pore.

2. isolated organ perfusion container according to claim 1, which is characterized in that the support plate is equipped with adjusting bracket, The adjusting bracket is installed in rotation in the support plate, and the adjusting bracket can be rotated to the Pan Kou for connecing drain cap Side；Bar hole is provided on the adjusting bracket, is provided with multiple card slots for clamping intrusion pipe on the hole wall of the bar hole successively.

3. isolated organ perfusion container according to claim 1, which is characterized in that described connect is equipped with supporting plate, institute in drain cap It states and multiple perforates is provided on supporting plate；Spacing is equipped between the supporting plate and the bottom for connecing drain cap.

4. isolated organ perfusion container according to claim 3, which is characterized in that the inner wall for connecing drain cap is equipped with more A connection bump is provided with the first location hole in the connection bump, and the first locating piece, first positioning are provided on the supporting plate Block is mutually clamped with first location hole.

5. isolated organ perfusion container according to claim 1, which is characterized in that be equipped on the outside of the disk mouth for connecing drain cap Installation base, the drain cap that connects are overlapped on by the installation base in the support plate.

6. isolated organ perfusion container according to claim 1, which is characterized in that the support plate is equipped with convex Band, the convex band is set along the edge of the support plate, and the convex band protrudes from the both sides of the support plate It sets；The inside of the convex band of the support plate one side and the side plate clearance fit on the chassis, the support plate opposite side Convex band inside and the upper cover clearance fit.

7. isolated organ perfusion container according to claim 1, which is characterized in that the bottom plate on the chassis is equipped with a plurality of add Strengthening tendons, the reinforcing rib are crossed to form at least one second location hole, and the bottom for connecing drain cap is equipped with the second locating piece, described Second locating piece is mutually clamped with second location hole.

8. isolated organ perfusion container according to claim 1, which is characterized in that the chassis is square plate；The side Plate includes the first side wall, second sidewall, the 3rd side wall and the 4th side wall, and the first side wall is opposite with the 3rd side wall to be set It puts, the second sidewall is oppositely arranged with the 4th side wall；The middle part of the first side wall is equipped with to be recessed into the chassis The first groove, the both sides of the 3rd side wall are equipped with the second groove being recessed into the chassis；The bottom of first groove Wall goes out pore equipped at least two intrusion pipes, and the bottom wall of two second grooves is equipped with via hole and a filling Pipe is noted into pore, an intrusion pipe is respectively equipped with into pore, the intrusion pipe in the second sidewall and the 4th side wall It is set into pore close to the 3rd side wall；Sensor mounting groove is provided on the second sidewall and the 4th side wall；It is described Into pore, two centres are located at the both sides of mounting hole, and the centre into pore for the centre there are two being set in support plate It is set into pore close to the 3rd side wall；The bottom for connecing drain cap is set there are three the leakage hole.

9. according to claim 1-8 any one of them isolated organ perfusion containers, which is characterized in that the isolated organ perfusion Container is the container of all-transparent.