CN107260234B - Braided degradable occluder - Google Patents

Abstract

The invention discloses a braided degradable occluder, comprising a wire braided mesh and a distal end and a proximal end respectively arranged at both ends of the wire braided mesh. A connection structure is provided, the upper end of the connection structure is connected with the distal end, and the lower end of the connection structure is connected with the proximal end or the wire braided mesh around the proximal end. The braided degradable occluder of the present invention is completely degradable, has better long-term effect on patients, and avoids complications of the occluder caused by other diseases in the long-term; "I" shape, the occluder fits better with the defect, ensuring the stability and occlusion of the occluder in the defect; the auxiliary line design can play an insurance role, when the occluder falls off, the auxiliary line can be used to recover, Avoid serious complications.

Description

Braided degradable occluder

technical field

The invention relates to a braided degradable occluder, belonging to the technical field of medical devices.

Background technique

Existing occluders are often in the shape of mushroom umbrellas made of nickel-titanium shape memory alloys, which are widely used in clinical practice. But its potential risks are as follows:

1. The occluder is implanted in the heart for a long time. If the peripheral blood vessels bulge, the occluder may wear the surrounding tissue and cause other diseases such as arterial dissection rupture;

2. With the development and growth of patients, some patients have a certain probability of developing long-term third-degree conduction block;

3. A small number of patients were found to be allergic to Ni ions after surgery, and they were intolerable to the occluder, which would cause other problems;

SUMMARY OF THE INVENTION

The technical problem to be solved by the present invention is: to provide a braided degradable occluder with good stability and occlusion performance, avoiding serious complications, and solving the problem that the existing occluder will wear the surrounding tissue and cause the patient to Long-term third-degree conduction block, the problem of intolerance to the occluder.

In order to solve the above technical problems, the technical solution of the present invention is to provide a braided degradable occluder, which includes a wire braided mesh and a distal end and a proximal end respectively disposed at both ends of the wire braided mesh. The wire braided net is provided with a connection structure, the upper end of the connection structure is connected to the distal end, and the lower end of the connection structure is connected to the proximal end or the wire braided mesh around the proximal end.

Preferably, the connecting structure includes at least two connecting rods, and each connecting rod is connected to the proximal end or the wire braided mesh around the proximal end through the mesh gap of the wire braided mesh.

Preferably, the connecting structure includes 2-6 connecting rods.

Preferably, the connecting structure is a cutting pipe or a curved wire; the upper end of the cutting pipe is connected to the distal end, and the lower end of the cutting pipe is provided with a connecting rod that is evenly divided; the curved wire includes a connecting rod.

Preferably, when each of the connecting rods is connected to the proximal end, each connecting rod is retracted toward the axial direction of the connecting structure.

Preferably, when each of the connecting rods is connected with the wire braided mesh around the proximal end, the head end of each connecting rod is provided with one or two hooks.

Preferably, when the head end of each connecting rod is provided with a hook, each connecting rod is folded toward the axial direction of the connecting structure.

Preferably, the distal end is provided with a ligation sleeve, and the wire braided mesh includes a disk surface and a waist connected to the disk surface.

Preferably, the material of the connecting structure is degradable material or metal material.

Preferably, the degradable material is polylactic acid, polydioxanone, PLGA; the metal material is nickel-titanium alloy, cobalt-chromium alloy.

The braided degradable occluder of the present invention is completely degradable, has better long-term effect on patients, and avoids complications of the occluder caused by other diseases in the long-term; "I" shape, the occluder fits better with the defect, ensuring the stability and occlusion of the occluder in the defect; the auxiliary line design can play an insurance role, when the occluder falls off, the auxiliary line can be used to recover, Avoid serious complications.

Description of drawings

Fig. 1 is a structural schematic diagram (1) of a braided degradable occluder when the connection structure is a pipe cutting;

Fig. 2 is a schematic structural diagram (2) of a braided degradable occluder when the connection structure is a pipe cutting;

Fig. 3 is a structural schematic diagram (3) of a braided degradable occluder when the connection structure is a pipe cutting;

Figure 4 is a top view of a braided degradable occluder;

Figure 5 is a schematic diagram of the release process of a braided degradable occluder

a. A schematic diagram of a braided degradable occluder before release;

b. A schematic diagram of a braided degradable occluder after release;

6 is a schematic structural diagram of a braided degradable occluder when the connecting structure is a curved wire

a. A schematic structural diagram of a braided degradable occluder when the lower end of the curved wire is provided with two hooks;

b. A schematic structural diagram of a braided degradable occluder when the lower end of the curved wire is provided with a hook;

c. A schematic structural diagram of a braided degradable occluder when the curved wire is folded in its axial direction.

Detailed ways

In order to make the present invention more obvious and comprehensible, preferred embodiments are described in detail below with reference to the accompanying drawings.

Example 1

Because the mechanical properties of degradable wire, such as superelasticity, are much weaker than that of shape memory alloy wire, in order to ensure that the occluder can achieve the expected effect of occlusion in clinical applications, it is necessary to compensate the occluder in structure. As shown in FIGS. 1-3 , a cutting tube (ie, connecting structure 3 ) is added to the upper end of the occluder, that is, the wire braided mesh 2 at the distal end of the braided degradable occluder of the present invention, and the upper end and the distal end of the cutting tube are Terminal 1 is fixedly connected.

The lower end of the cutting pipe is evenly divided into 4 connecting rods 3-1, as shown in Figure 4, each connecting rod 3-1 is folded in the axial direction of the cutting pipe, as shown in Figure 1, when the plug is blocked After the release of the device, with the help of the auxiliary wire, each connecting rod 3-1 at the lower end of the cutting tube passes through the mesh gap of the wire braided mesh 2, and is closed in the direction of the axis to clamp the occluder. The proximal end 4 of the occluder is placed so that the straight line distance between the two ends of the occluder is consistent with the length of the cut pipe. At this time, the occluder is stabilized in the "I" shape to ensure that the occluder does not fall off. -2 both have the effect of blocking and achieve the effect of mechanical supplementation.

The material for cutting the pipe can be a degradable material, and the degradable material is polylactic acid, polydioxanone, PLGA, etc.; the material for cutting the pipe can also be a metal material, and the metal material is nickel-titanium alloy, cobalt-chromium alloy .

As shown in a and b in Figure 5, the occluder grid is passed through the fine sheath in the two symmetrical small cavities to ensure that the auxiliary wires are not entangled together. The auxiliary thread is passed through the mesh of the wire braided mesh 2 of the occluder and bypassed at the distal end of the occluder. During operation, one end of the auxiliary wire is at the end of the occluder, and the other end is at the end of the sheath tube. The ligation sleeve 1-1 of the end 1 and the cutting pipe travel back, and the "I"-shaped platform of the "I"-shaped occluder forms a "wine glass" shape when the auxiliary line is pulled to ensure that the occluder does not fall off, and at the same time Both the disk surface 2-1 and the waist 2-2 have the effect of blocking, realizing the mechanical compensation effect, so as to achieve the same blocking effect as the NiTi shape memory alloy. When the clamping position of the cutting tube is well fixed, cut the auxiliary wire at the joint of the sheath tube, pull a broken end, pull the auxiliary wire out of the occluder, and finally withdraw it together with the sheath tube.

Example 2

As shown in Figure 2, the lower end of the cutting pipe is evenly divided into four connecting rods 3-1, each connecting rod 3-1 is folded in the axial direction of the cutting pipe, and each connecting rod on the cutting pipe is The head end of 3-1 is provided with a hook 3-2. When the occluder is released, the cutting pipe is assisted by the pullback of the auxiliary line, and each connecting rod 3-1 at the lower end of the cutting pipe passes through the occluder. The mesh gap of the wire braided mesh 2 is closed in the direction of the axis, and at the same time, the hook 3-2 is hooked to the proximal end 4 of the occluder or the wire/grid of the wire mesh 2 near the proximal end 4 , so that the straight line distance between the two ends of the occluder is consistent with the length of the cut pipe. At this time, the occluder is stable in the "I" shape to ensure that the occluder does not fall off. The effect of blocking is realized, and the effect of mechanical supplementation is realized.

Others are the same as in Example 1.

Example 3

As shown in Figure 3, the lower end of the cutting pipe is evenly split into four connecting rods 3-1, and each connecting rod 3-1 may not be folded in the axial direction of the cutting pipe. Two hooks 3-2, when the occluder is released, the cutting pipe is assisted by the pullback of the auxiliary line, and each connecting rod 3-1 at the lower end of the cutting pipe passes through the wire braided mesh 2 of the occluder The mesh gap of the occluder 3-2 is tightly hooked to the proximal end 4 of the occluder or the wire/mesh of the wire woven mesh 2 near the proximal end 4, so that the straight line distance between the two ends of the occluder is the same as the cutting distance. The length of the pipe is the same. At this time, the occluder is stable in the "I" shape to ensure that the occluder does not fall off. At the same time, both the disk surface 2-1 and the waist 2-2 have the effect of blocking, achieving the effect of mechanical supplementation.

Others are the same as in Example 1.

Example 4

As shown in a, b, and c in Figure 6, the occluder can also replace the curved wire with the cutting pipe (that is, the connecting structure 3 is a curved wire). intended purpose.

Others are the same as in Example 1.

Example 5

In this embodiment, the cutting pipe can be divided into two connecting rods 3-1.

Others are the same as in Example 1.

Example 6

In this embodiment, the cutting pipe can be divided into six connecting rods 3-1.

Others are the same as in Example 1.

Claims (7)

1. A braided degradable occluder, comprising a wire braided mesh (2) and a distal end (1) and a proximal end (4) respectively arranged at both ends of the wire braided mesh (2), characterized in that: In that, the wire braided net (2) is provided with a connecting structure (3), and the upper end of the connecting structure (3) is connected with the distal end (1), The lower end of the connecting structure (3) is evenly divided into at least two connecting rods (3-1), and each connecting rod (3-1) is closed in the axial direction of the connecting structure (3); when the occluder is released , each connecting rod (3-1) at the lower end of the connecting structure (3) passes through the grid gaps of the wire braided mesh (2), and is closed in the axial direction to clamp the proximal end (4) of the occluder. , so that the linear distance between the two ends of the occluder is consistent with the length of the connecting structure (3), and the occluder is stable in the "I" shape at this time. 2. A braided degradable occluder, comprising a wire braided mesh (2) and a distal end (1) and a proximal end (4) respectively arranged at both ends of the wire braided mesh (2), characterized in that: In that, the wire braided net (2) is provided with a connecting structure (3), and the upper end of the connecting structure (3) is connected with the distal end (1), The lower end of the connecting structure (3) is evenly divided into at least two connecting rods (3-1), and each connecting rod (3-1) is folded in the axial direction of the connecting structure (3), and is in the connecting structure (3) The head end of each connecting rod (3-1) is provided with a hook (3-2); when the occluder is released, each connecting rod (3-1) at the lower end of the connecting structure (3) passes through the seal. The mesh gaps of the wire braided mesh (2) of the occluder are closed in the direction of the axis, and at the same time, the hooks (3-2) are hooked tightly to the proximal end (4) or the vicinity of the proximal end (4) of the occluder The wire or mesh of the wire woven mesh (2) makes the linear distance between the two ends of the occluder consistent with the length of the connecting structure (3), and the occluder is stabilized in the "I" shape at this time. The braided degradable occluder according to claim 1 or 2, characterized in that, the connecting structure (3) comprises 2-6 connecting rods (3-1). 4. A braided degradable occluder according to claim 1 or 2, wherein the connecting structure (3) is a cutting pipe or a curved wire; the upper end of the cutting pipe and the distal end ( 1) Connecting, the lower end of the cutting pipe is provided with a connecting rod (3-1) which is evenly divided; the bending wire includes a connecting rod (3-1). 5. A braided degradable occluder according to claim 1 or 2, characterized in that, a ligation sleeve (1) is provided on the distal end (1), and the wire braided mesh (2) comprising a disk surface (2-1) and a waist (2-2) connected with the disk surface (2-1). 6. A braided degradable occluder according to claim 1 or 2, characterized in that, the material of the connecting structure (3) is a degradable material or a metal material. 7. A braided degradable occluder as claimed in claim 6, wherein the degradable material is polylactic acid, polydioxanone, PLGA; the metal material is nickel-titanium alloy, cobalt Chrome alloy.

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