CN103463500B - Medicament for treating cerebral hemorrhage - Google Patents
Medicament for treating cerebral hemorrhage Download PDFInfo
- Publication number
- CN103463500B CN103463500B CN201310444677.XA CN201310444677A CN103463500B CN 103463500 B CN103463500 B CN 103463500B CN 201310444677 A CN201310444677 A CN 201310444677A CN 103463500 B CN103463500 B CN 103463500B
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- radix
- portions
- cerebral hemorrhage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 44
- 206010008111 Cerebral haemorrhage Diseases 0.000 title claims abstract description 36
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 241001163443 Daphne giraldii Species 0.000 claims description 17
- 241000628997 Flos Species 0.000 claims description 17
- 210000000582 semen Anatomy 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000004615 ingredient Substances 0.000 claims description 13
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000012153 distilled water Substances 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 9
- 241000218211 Maclura Species 0.000 claims description 8
- 241000736026 Sarcandra Species 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 3
- -1 boil 2 ~ 3 hours Substances 0.000 claims description 3
- 238000007598 dipping method Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 11
- 230000003213 activating effect Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 244000036905 Benincasa cerifera Species 0.000 abstract 1
- 235000011274 Benincasa cerifera Nutrition 0.000 abstract 1
- 241000410367 Clerodendrum thomsoniae Species 0.000 abstract 1
- 241000227286 Craibiodendron yunnanense Species 0.000 abstract 1
- 235000015001 Cucumis melo var inodorus Nutrition 0.000 abstract 1
- 240000004784 Cymbopogon citratus Species 0.000 abstract 1
- 235000017897 Cymbopogon citratus Nutrition 0.000 abstract 1
- 241000934856 Daphne Species 0.000 abstract 1
- 240000002373 Ficus pumila Species 0.000 abstract 1
- 235000006718 Ficus pumila Nutrition 0.000 abstract 1
- 241001247806 Hylomecon japonica Species 0.000 abstract 1
- 241000782535 Hypericum sampsonii Species 0.000 abstract 1
- 241000092461 Laportea macrostachya Species 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 240000005523 Peganum harmala Species 0.000 abstract 1
- 235000005126 Peganum harmala Nutrition 0.000 abstract 1
- 241000545263 Salacia <hydroid> Species 0.000 abstract 1
- 240000004274 Sarcandra glabra Species 0.000 abstract 1
- 235000010842 Sarcandra glabra Nutrition 0.000 abstract 1
- 241001556408 Ventilago leiocarpa Species 0.000 abstract 1
- 241000278700 Wikstroemia canescens Species 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000001502 supplementing effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 description 16
- 230000036407 pain Effects 0.000 description 15
- 208000024891 symptom Diseases 0.000 description 12
- 239000008280 blood Substances 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 11
- 208000014674 injury Diseases 0.000 description 11
- 231100000614 poison Toxicity 0.000 description 11
- 230000008736 traumatic injury Effects 0.000 description 11
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 208000008035 Back Pain Diseases 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 6
- 208000008930 Low Back Pain Diseases 0.000 description 6
- 241000411851 herbal medicine Species 0.000 description 6
- 230000007096 poisonous effect Effects 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 5
- 206010019233 Headaches Diseases 0.000 description 5
- 206010019468 Hemiplegia Diseases 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 230000008961 swelling Effects 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 208000025747 Rheumatic disease Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 208000002173 dizziness Diseases 0.000 description 4
- 231100000869 headache Toxicity 0.000 description 4
- 230000023597 hemostasis Effects 0.000 description 4
- 235000008216 herbs Nutrition 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000002175 menstrual effect Effects 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 230000000552 rheumatic effect Effects 0.000 description 4
- 201000003068 rheumatic fever Diseases 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 208000026106 cerebrovascular disease Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 208000011580 syndromic disease Diseases 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 208000010392 Bone Fractures Diseases 0.000 description 2
- 206010008190 Cerebrovascular accident Diseases 0.000 description 2
- 206010013952 Dysphonia Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 206010037549 Purpura Diseases 0.000 description 2
- 241001672981 Purpura Species 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 208000006011 Stroke Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 201000004792 malaria Diseases 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 230000000472 traumatic effect Effects 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical compound Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 208000010470 Ageusia Diseases 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 241000003910 Baronia <angiosperm> Species 0.000 description 1
- 206010065559 Cerebral arteriosclerosis Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010016326 Feeling cold Diseases 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010018092 Generalised oedema Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010021639 Incontinence Diseases 0.000 description 1
- 206010024453 Ligament sprain Diseases 0.000 description 1
- 241000406668 Loxodonta cyclotis Species 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241000219000 Populus Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 208000008765 Sciatica Diseases 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 208000008630 Sialorrhea Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 208000010513 Stupor Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010043866 Tinea capitis Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 208000009443 Vascular Malformations Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethanethiol Chemical compound CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 201000005851 intracranial arteriosclerosis Diseases 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 210000001699 lower leg Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000001617 migratory effect Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 201000005737 orchitis Diseases 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003119 painkilling effect Effects 0.000 description 1
- 208000035824 paresthesia Diseases 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000037081 physical activity Effects 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 210000001113 umbilicus Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a medicament for treating cerebral hemorrhage, and belongs to the field of traditional Chinese medicines. The effective components of the medicament comprise raw materials: winter melon vine, laportea macrostachya, hypericum sampsonii, ficus pumila, peganum harmala, craibiodendron yunnanense, wikstroemia canescens, sargent craneberrybuch branchlet, lemongrass, cortex daphnes, ventilago leiocarpa benth, hylomecon japonica, mulberry roots, sarcandra glabra, clerodendrum thomsonae and prinos-like salacia root. The medicament of the invention has efficacies of supplementing the center, boosting qi, softening blood vessels, freeing the channels, activating collaterals, enlivening spirit and opening the orifices, has substantial treatment effect on cerebral hemorrhage, and is fast in effectiveness and none in toxic and side effects; the medicament is verified by clinics that the medicament has good treatment effect on cerebral hemorrhage and sequelaes caused thereby; and the medicament has the advantages of easily available medicinal material, low cost, high cure rate, no sequelae, safety and reliability, and is worth widely popularizing and applying.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine for the treatment of cerebral hemorrhage.
Background technology
It is hemorrhage that cerebral hemorrhage refers to that angiorrhexis in non-traumatic cerebral essence causes, the modal cause of disease is hypertension, cerebral arteriosclerosis, intracranial vascular malformation etc., normal because of firmly, the factor such as excited brings out, therefore most aprowl sudden onset, cerebral hemorrhage morbidity is very rapid clinically, and main manifestations is the neural infringements such as disturbance of consciousness, hemiplegia of limb, aphasia; Cerebral hemorrhage onset is hurried, the state of an illness is dangerous, mortality rate is very high, it is one the most serious in acute cerebrovascular disease, for current middle-aged and elderly people fatal disease it-, because it is dead and disability rate is high, so national governments and hygiene department all very pay attention to its preventing and controlling.Epidemiological study shows, the prevalence of cerebrovascular is 500-700,/10 ten thousand population, domestic and international statistics are basically identical, China urban is up to 10,00/,100,000 populations, annual sickness rate is 165-245,/10 ten thousand population, the statistics national according to World Health Organization's cerebrovascular cooperative groups 57, what cerebrovascular was classified as front 3 kinds of causes of death has 40 countries, the patient died of illness because of cerebrovascular accounts for 11.3% of 57 national general mortality rate, and majority state mortality of cerebrovascular disease rate is close to 1,00/,100,000 population years.China is one of district occurred frequently of cerebrovascular in world wide, and cerebrovascular is the deputy cause of death of resident nearly ten years always, is only second to malignant tumor, and some cities, the north have risen to first.The case fatality rate of cerebral hemorrhage is 40-60%, account for the major part in mortality of cerebrovascular disease number, all right both at home and abroad: in survivor 70-80% leave invalid, and about 40% attach most importance to residual, huge life threat is caused to patient, quality of life is had a strong impact on simultaneously, causes white elephant also to patient home and even entire society.
Western medicine cerebral hemorrhage, is used for acute stages treated, and the shortcoming of Western medicine is that action target spot is single, therefore clinical effectiveness can not be fully up to expectations, so for apoplexy sequela patient, only have treatment by Chinese herbs, efficacy enhancing and toxicity reducing can be reached, the therapeutic effect for the treatment of both the principal and secondary aspects of a disease, but existing treatment by Chinese herbs is long for the course for the treatment of, easily recurs, so clinical in the urgent need to one for the complicated pathogenesis of cerebral hemorrhage, determined curative effect, convenient and safe, stay-in-grade first aid using medicine.
Summary of the invention
The invention provides a kind of medicine for the treatment of cerebral hemorrhage, there is effect of invigorating the spleen and replenishing QI, vessel softening, dredge the meridian passage, consciousness and resuscitation restoring, evident in efficacy to treatment cerebral hemorrhage, instant effect, have no side effect, to treatment cerebral hemorrhage and the sequela that causes thereof, there is good therapeutic effect through clinical verification; Medicine medicinal raw material of the present invention is easy to get, and with low cost, cure rate is high, does not stay sequela and safe and reliable, and should be widely promoted application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for cerebral hemorrhage, raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 59 ~ 84 parts of Radix Laporteae Macrostachyaes 54 ~ 79 portions of Herba Hyperici Sampsoniis 53 ~ 79 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 49 ~ 74 parts
Herba pegani harmalae 45 ~ 72 parts of Folium Craibiodendri Yunnanensiss 44 ~ 69 parts of Flos Wikstroemiae Dolichanthaes 41 ~ 64 parts of Folium et Cacumen Viburni Sargentii 39 ~ 60 parts
Herba Cymbopogonis Citrari 39 ~ 59 parts of Daphne giraldii Nitsche 36 ~ 55 parts of Radix Cudraniaes 34 ~ 54 portions of Semen Hoveniae (Fructus Hoveniae)s 7 34 ~ 47 parts
Radix Mori 29 ~ 44 parts of Herba Sarcandraes 26 ~ 42 parts of Herba Anagallidis Arvensiss 19 ~ 39 portions of Radix salaciae prinoidiss 10 ~ 29 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 64 ~ 79 parts of Radix Laporteae Macrostachyaes 59 ~ 75 portions of Herba Hyperici Sampsoniis 55 ~ 74 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 54 ~ 66 parts
Herba pegani harmalae 49 ~ 69 parts of Folium Craibiodendri Yunnanensiss 47 ~ 64 parts of Flos Wikstroemiae Dolichanthaes 44 ~ 62 parts of Folium et Cacumen Viburni Sargentii 43 ~ 57 parts
Herba Cymbopogonis Citrari 42 ~ 54 parts of Daphne giraldii Nitsche 39 ~ 52 parts of Radix Cudraniaes 37 ~ 49 portions of Semen Hoveniae (Fructus Hoveniae)s 7 35 ~ 44 parts
Radix Mori 32 ~ 41 parts of Herba Sarcandraes 29 ~ 39 parts of Herba Anagallidis Arvensiss 22 ~ 29 portions of Radix salaciae prinoidiss 14 ~ 24 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 69 ~ 74 parts of Radix Laporteae Macrostachyaes 64 ~ 70 portions of Herba Hyperici Sampsoniis 59 ~ 69 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 57 ~ 65 parts
Herba pegani harmalae 54 ~ 64 parts of Folium Craibiodendri Yunnanensiss 51 ~ 59 parts of Flos Wikstroemiae Dolichanthaes 49 ~ 59 parts of Folium et Cacumen Viburni Sargentii 47 ~ 54 parts
Herba Cymbopogonis Citrari 44 ~ 49 parts of Daphne giraldii Nitsche 42 ~ 48 parts of Radix Cudraniaes 39 ~ 44 portions of Semen Hoveniae (Fructus Hoveniae)s 7 38 ~ 41 parts
Radix Mori 34 ~ 39 parts of Herba Sarcandraes 32 ~ 34 parts of Herba Anagallidis Arvensiss 24 ~ 26 portions of Radix salaciae prinoidiss 17 ~ 19 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 72 parts of Radix Laporteae Macrostachyaes 67 portions of Herba Hyperici Sampsoniis 64 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 62 parts
Herba pegani harmalae 59 parts of Folium Craibiodendri Yunnanensiss 55 parts of Flos Wikstroemiae Dolichanthaes 54 parts of Folium et Cacumen Viburni Sargentii 50 parts
Herba Cymbopogonis Citrari 47 parts of Daphne giraldii Nitsche 45 parts of Radix Cudraniaes 42 portions of Semen Hoveniae (Fructus Hoveniae)s 7 39 parts
Radix Mori 37 parts of Herba Sarcandraes 33 parts of Herba Anagallidis Arvensiss 25 portions of Radix salaciae prinoidiss 18 parts.
Treat a preparation method for the medicine of cerebral hemorrhage, comprise following processing step:
(1) Herba Hyperici Sampsonii, Herba pegani harmalae, Flos Wikstroemiae Dolichanthae, Herba Cymbopogonis Citrari, Daphne giraldii Nitsche, Radix Cudraniae, Radix Mori and Herba Sarcandrae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Folium Craibiodendri Yunnanensis and Folium et Cacumen Viburni Sargentii are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(3) Caulis Benincasae, Caulis fici pumilae (Fructus Fici Pumilae) and Herba Anagallidis Arvensis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Radix Laporteae Macrostachyae, Semen Hoveniae (Fructus Hoveniae) seven and Radix salaciae prinoidis are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.18, for subsequent use;
(5) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), add adjuvant, utilize modern advanced pharmacy science and technology, make tablet, obtain the medicine for the treatment of cerebral hemorrhage of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Caulis Benincasae: bitter in the mouth, cold in nature; Return lung, Liver Channel.Removing heat from the lung and dissipating phlegm, dredge the meridian passage.Main lung-heat expectoration, articular instability, proctoptosis, skin ulcer scabies." book on Chinese herbal medicine is new again " carries: " actively stimulate the menstrual flow, sharp joint, and vim and vigour, dry and chase after wind.”
Radix Laporteae Macrostachyae: pungent, bitter, cold, slightly poisonous.Wind-damp dispelling, the meridian dredging, removing toxic substances and promoting subsidence of swelling.Cure mainly lumbago and skelalgia, apathetic, migratory arthralgia edema, tuberculous lymphadenitis, venom.
Herba Hyperici Sampsonii: bitter, pungent, cold; Return liver, spleen channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing, promoting blood flow to regulate menstruation, dispelling wind and removing obstruction in the collateral.Main haematemesis, spitting of blood, epistaxis, stranguria with blood, menoxenia, dysmenorrhea, leucorrhea, traumatic injury, rheumatic arthralgia, lumbago and skelalgia, external also can control tinea capitis, aphtha, corneal nebula." vegetation is side just " carries: " hemostasis, analgesic therapy, convenient, stimulate the menstrual flow, stimulating milk secretion, expedites the emergence of.”
Caulis fici pumilae (Fructus Fici Pumilae): sour in the mouth, cool in nature.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome, sciatica, dysentery, urine drenches, edema, malaria, amenorrhea, and postnatal blood stasis is suffered from abdominal pain, laryngopharynx swelling and pain, orchitis, dermatitis rhus, pain pyogenic infections from tumour or sore, traumatic injury." Chinese herbal medicine is commonly used in Shanghai " carries: " wind-damp dispelling, dredge the meridian passage, clearing heat for detumescence, diuresis, hemostasis.Dispelling the wind and dampness pathogens pain, brothers' articular instability.”
Herba pegani harmalae: sour, sweet is flat, poisonous.Lung qi dispersing cough-relieving, wind-damp dispelling, removing toxic substances; Cough and asthma; Innominate toxic swelling is controlled in external, rheumatic arthritis." the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " carries: " lung qi dispersing cough-relieving, dredge the meridian passage, removing toxic substances dehumidifying.Control tracheitis, rheumatic arthritis, palpitation and short breath, headache, dizzy "
Folium Craibiodendri Yunnanensis: pungent, puckery, temperature, poisonous.Eliminating stasis to stop pain, expelling wind and removing dampness, stops blooding sensible.For traumatic injury, traumatic stupor, bruise, lumbago and skelalgia, hemiplegia, paralysis, rheumatic arthritis, traumatic hemorrhage, fracture." Yunnan Chinese herbal medicine " carries: " relieving superficies and warmign meridians, activating collaterals to relieve pain.Control traumatic injury, rheumatic numbness, affection of exogenous wind-cold.”
Flos Wikstroemiae Dolichanthae: acrid in the mouth is bitter, cold in nature, poisonous; Return stomach warp.Removing fluid-retention by purgation, disappear hard removing mass.Main phlegm retention, cough with dyspnea, edema, generalized edema with distention of the chest and abdomen in larynx, lump in the abdomen mass beside the umbilicus." herbal classic " carries: " main typhoid fever pyrexial malaria, lower 12 water, removing mass is poly-, large hard lump in the abdomen, cleanses in the intestines and stomach and stays addiction, diet, cold and heat pathogen, dredging water passages.”
Folium et Cacumen Viburni Sargentii: sweet in the mouth, bitter, property is put down.Dredge the meridian passage, detoxifying and relieving itching.Main lumbago and skelalgia, lumbar sprain and QI divergeny, furuncle, scabies, skin pruritus." Jilin Chinese herbal medicine " carries: " dredge the meridian passage, hemostasis, analgesia, cough-relieving.Control pain in the low back and legs, traumatic injury.”
Herba Cymbopogonis Citrari: pungent, temperature, sweet.Dispelling wind and removing obstruction in the collateral, warming middle-JIAO to relieve pain, antidiarrheal, main flu head-body-pain, anemofrigid-damp arthralgia, coldness and pain in the epigastrium, has loose bowels, traumatic injury." south of the Five Ridges gather medicinal herbs record " carries: " loose traumatic injury hinders blood stasis, the meridian dredging.Wind syndrome of head pain, decocts washing with it.Herba Cymbopogonis Citrari and rice are fried together, add decocting drink, sealing rushes down.Decoct washing body, detumescence of can dispeling the wind, separate stench.Extract its oil, can only suffer from abdominal pain.”
Daphne giraldii Nitsche: bitter, pungent, temperature, slightly poisonous.Dispelling wind and removing obstruction in the collateral, stasis-dispelling and pain-killing, for headache, toothache, rheumatic arthritis, traumatic injury, stomachache, pain in the hepatic region." Shaanxi Chinese herbal medicine " carries: " cure cold, rheumatalgia, apoplexy is numb, hemiplegia, itchy skin eruption.”
Radix Cudraniae: micro-hardship is flat.Relieving cough and resolving phlegm, expelling wind and removing dampness, eliminating stasis to stop pain.For pulmonary tuberculosis, icterohepatitis, hepatosplenomegaly, taste-blindness rate, rheumatic lumbago and scelalgia; Fracture is controlled in external, traumatic injury." Nanning City's medicine will " carries: " blood stimulates the menstrual flow, and controls stranguria with turbid discharge, goes long-pending, the calculus of the many years ago stasis of blood.”
Semen Hoveniae (Fructus Hoveniae) seven: bitter, flat.Dispelling wind and removing obstruction in the collateral, dissipating blood stasis for subsidence of swelling.Main air pain of dampness syndrome, traumatic injury.
Radix Mori: micro-hardship, cold in nature; Return Liver Channel.Heat clearing away is calmed the frightened, dispelling wind and removing obstruction in the collateral; Main infantile convulsion, conjunctival congestion, toothache, bones and muscles pain." Nanjing medicinal herbs among the people " carry: " control bones and muscles pain, hypertension.”
Herba Sarcandrae: bitter, pungent, flat; GUIXIN, Liver Channel.Clearing away heat and cooling blood, speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral.For heat in blood purpura, purpura, rheumatic arthralgia, traumatic injury.
Herba Anagallidis Arvensis: sour-puckery flavor is nontoxic.Control all poisonous snakes or lyssodexis, strand juice takes orally, and slag applies affected part, controls again cloudy disease skin infection and the arthroncus of knee.
Radix salaciae prinoidis: puckery, temperature; Return liver, kidney channel.Dispelling wind and removing obstruction in the collateral, restores menstrual flow and invigorates blood circulation.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved, blood pain lumbago.
The present invention compared with prior art, has following beneficial effect:
Medicine of the present invention has effect of invigorating the spleen and replenishing QI, vessel softening, dredge the meridian passage, consciousness and resuscitation restoring, and evident in efficacy to treatment cerebral hemorrhage, instant effect, has no side effect, and has good therapeutic effect through clinical verification to treatment cerebral hemorrhage and the sequela that causes thereof; Medicine medicinal raw material of the present invention is easy to get, and with low cost, cure rate is high, does not stay sequela and safe and reliable, and should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Caulis Benincasae 79g Radix Laporteae Macrostachyae 75g Herba Hyperici Sampsonii 74g Caulis fici pumilae (Fructus Fici Pumilae) 66g
Herba pegani harmalae 69g Folium Craibiodendri Yunnanensis 64g Flos Wikstroemiae Dolichanthae 62g Folium et Cacumen Viburni Sargentii 57g
Herba Cymbopogonis Citrari 54g Daphne giraldii Nitsche 52g Radix Cudraniae 49g Semen Hoveniae (Fructus Hoveniae) seven 44g
Radix Mori 41g Herba Sarcandrae 39g Herba Anagallidis Arvensis 29g Radix salaciae prinoidis 24g.
Treat a preparation method for the medicine of cerebral hemorrhage, comprise following processing step:
(1) Herba Hyperici Sampsonii, Herba pegani harmalae, Flos Wikstroemiae Dolichanthae, Herba Cymbopogonis Citrari, Daphne giraldii Nitsche, Radix Cudraniae, Radix Mori and Herba Sarcandrae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Folium Craibiodendri Yunnanensis and Folium et Cacumen Viburni Sargentii are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(3) Caulis Benincasae, Caulis fici pumilae (Fructus Fici Pumilae) and Herba Anagallidis Arvensis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Radix Laporteae Macrostachyae, Semen Hoveniae (Fructus Hoveniae) seven and Radix salaciae prinoidis are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.18, for subsequent use;
(5) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), add adjuvant, utilize modern advanced pharmacy science and technology, make tablet, obtain the medicine for the treatment of cerebral hemorrhage of the present invention.
Usage and dosage: oral, every day 2 times, each 2 (every sheet 0.5g), warm water delivery service after meal; Within 9 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Caulis Benincasae 74g Radix Laporteae Macrostachyae 70g Herba Hyperici Sampsonii 69g Caulis fici pumilae (Fructus Fici Pumilae) 65g
Herba pegani harmalae 64g Folium Craibiodendri Yunnanensis 59g Flos Wikstroemiae Dolichanthae 59g Folium et Cacumen Viburni Sargentii 54g
Herba Cymbopogonis Citrari 49g Daphne giraldii Nitsche 48g Radix Cudraniae 44g Semen Hoveniae (Fructus Hoveniae) seven 41g
Radix Mori 39g Herba Sarcandrae 34g Herba Anagallidis Arvensis 26g Radix salaciae prinoidis 19g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Caulis Benincasae 72g Radix Laporteae Macrostachyae 67g Herba Hyperici Sampsonii 64g Caulis fici pumilae (Fructus Fici Pumilae) 62g
Herba pegani harmalae 59g Folium Craibiodendri Yunnanensis 55g Flos Wikstroemiae Dolichanthae 54g Folium et Cacumen Viburni Sargentii 50g
Herba Cymbopogonis Citrari 47g Daphne giraldii Nitsche 45g Radix Cudraniae 42g Semen Hoveniae (Fructus Hoveniae) seven 39g
Radix Mori 37g Herba Sarcandrae 33g Herba Anagallidis Arvensis 25g Radix salaciae prinoidis 18g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Caulis Benincasae 69g Radix Laporteae Macrostachyae 64g Herba Hyperici Sampsonii 59g Caulis fici pumilae (Fructus Fici Pumilae) 57g
Herba pegani harmalae 54g Folium Craibiodendri Yunnanensis 51g Flos Wikstroemiae Dolichanthae 49g Folium et Cacumen Viburni Sargentii 47g
Herba Cymbopogonis Citrari 44g Daphne giraldii Nitsche 42g Radix Cudraniae 39g Semen Hoveniae (Fructus Hoveniae) seven 38g
Radix Mori 34g Herba Sarcandrae 32g Herba Anagallidis Arvensis 24g Radix salaciae prinoidis 17g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Caulis Benincasae 64g Radix Laporteae Macrostachyae 59g Herba Hyperici Sampsonii 55g Caulis fici pumilae (Fructus Fici Pumilae) 54g
Herba pegani harmalae 49g Folium Craibiodendri Yunnanensis 47g Flos Wikstroemiae Dolichanthae 44g Folium et Cacumen Viburni Sargentii 43g
Herba Cymbopogonis Citrari 42g Daphne giraldii Nitsche 39g Radix Cudraniae 37g Semen Hoveniae (Fructus Hoveniae) seven 35g
Radix Mori 32g Herba Sarcandrae 29g Herba Anagallidis Arvensis 22g Radix salaciae prinoidis 14g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of cerebral hemorrhage, select the routine clinical observation of patients with cerebral hemorrhage 200 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein male 47 example, women 53 example, 41 ~ 83 years old age, 60.4 years old mean age, the shortest person of the course of disease 8 months, most elder 15 years, average 7.9 years.Matched group 100 example, wherein male 48 example, women 52 example, 40 ~ 82 years old age, 61.6 years old mean age, the shortest person of the course of disease 7 months, most elder 16 years, average 8.3 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 2, warm water delivery service after meal; Within 9 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Matched group takes refreshment reworking capsule, warm yellow wine or warm water delivery service, every day 2 times, each 4; Within 15 days, be 1 course for the treatment of, the lighter takes effect 3 courses for the treatment of, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: sings and symptoms disappears, and can live on one's own life.
(2) effective: symptom and sign take a turn for the better, the action of energy cane, basic living can be taken care of oneself.
(3) effective: symptom and sign take a turn for the better to some extent, substantially can cane action.
(4) invalid: sings and symptoms is all without improvement, and symptom is as front.
4, result:
Select in the treatment group of medicine of the present invention, cure 36 examples, effective 33 examples, effective 29 examples, invalid 2 examples, cure rate 36%, total effective rate 98%.
15 examples are cured, effective 19 examples, effective 20 examples, invalid 46 examples, cure rate 15%, total effective rate 54% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Liu, female, 45 years old, people from Cangzhou, Hebei, the sudden cerebral hemorrhage of patient, because rescuing in time, kept life, but patient left side body movement is limited, blood pressure did not decline all the time, seeks medical advice everywhere, and it is invalid to control for a long time.After taking 1 course for the treatment of of medicine of the present invention, left half body limbs can gentle activity, and speech changes to some extent, and memory also strengthens to some extent, and after taking again 2 courses for the treatment of of medicine of the present invention, hypertension symptom now recovers normal substantially, lives and also can take care of oneself.
2, fine strain of millet, man, 57 years old, Yuncheng, Shanxi people, fall in a swoon suddenly because going to work in the fields, syncope, was diagnosed as cerebral hemorrhage.Timely symptomatic treatment more than ten sky is rescued, patient's facial hemiparalysis, dysphonia, hemiplegia through hospital.After taking 2 courses for the treatment of of medicine of the present invention, the transference cure such as facial hemiparalysis, dysphonia, language is clear, and walking freely.
3, poplar, female, 63 years old, people from Shenyang, Liaoning, patient tumbles because of carelessness, causes left side cerebral hemorrhage, doctor considers that patient is conscious, does not do operation of opening cranium, employing be the method for Drug therapy, current patient's right hand, foot active receiving limit, and make not energetically, self feel pins and needles in one's hands and feet after people's special operations, freely, after taking 1 course for the treatment of of medicine of the present invention, the right hand can capture thing in its left half body activity, right crus of diaphragm activity is nimble, can walk down.
4, Huang, man, 71 years old, people from Dalian, patient's sudden onset, with dizziness, headache, vomiting, disppointment, sialorrhea, distortion of commissure and half body paralysis, incontinence of urination and defecation; Examine as cerebral hemorrhage.Take 1 course for the treatment of of medicine of the present invention, symptom is eased, and continues to take 2 courses for the treatment of, and symptom disappears completely, cures.
5, Jiang, female, 79 years old, people from Yangzhou, Jiangsu, patients with clinical manifestations is: the stiff Gou contraction of hemiplegia, Ipsilateral, headache are dizzy, flushed complexion tinnitus, and dry mouth and throat, deep red tongue, yellow and thin fur, stringy pulse are firmly strong; Examine as cerebral hemorrhage.Take 3 courses for the treatment of of Drug therapy of the present invention, symptom disappears completely, cures.Follow up a case by regular visits to, so far without recurrence.
6, Cao, man, 80 years old, Zhejiang Hangzhou people, patient's dizziness, right hemianesthesia, right lower limb send out directly, on foot jolt, the right hand is dumb; Laboratory examination result is cerebral hemorrhage.Take 1 course for the treatment of of medicine of the present invention, symptom disappears substantially; Continue to take 2 courses for the treatment of, symptom disappears completely, and life can be taken care of oneself.
Claims (5)
1. treat a medicine for cerebral hemorrhage, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 59 ~ 84 parts of Radix Laporteae Macrostachyaes 54 ~ 79 portions of Herba Hyperici Sampsoniis 53 ~ 79 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 49 ~ 74 parts
Herba pegani harmalae 45 ~ 72 parts of Folium Craibiodendri Yunnanensiss 44 ~ 69 parts of Flos Wikstroemiae Dolichanthaes 41 ~ 64 parts of Folium et Cacumen Viburni Sargentii 39 ~ 60 parts
Herba Cymbopogonis Citrari 39 ~ 59 parts of Daphne giraldii Nitsche 36 ~ 55 parts of Radix Cudraniaes 34 ~ 54 portions of Semen Hoveniae (Fructus Hoveniae)s 7 34 ~ 47 parts
Radix Mori 29 ~ 44 parts of Herba Sarcandraes 26 ~ 42 parts of Herba Anagallidis Arvensiss 19 ~ 39 portions of Radix salaciae prinoidiss 10 ~ 29 parts.
2. a kind of medicine for the treatment of cerebral hemorrhage according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 64 ~ 79 parts of Radix Laporteae Macrostachyaes 59 ~ 75 portions of Herba Hyperici Sampsoniis 55 ~ 74 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 54 ~ 66 parts
Herba pegani harmalae 49 ~ 69 parts of Folium Craibiodendri Yunnanensiss 47 ~ 64 parts of Flos Wikstroemiae Dolichanthaes 44 ~ 62 parts of Folium et Cacumen Viburni Sargentii 43 ~ 57 parts
Herba Cymbopogonis Citrari 42 ~ 54 parts of Daphne giraldii Nitsche 39 ~ 52 parts of Radix Cudraniaes 37 ~ 49 portions of Semen Hoveniae (Fructus Hoveniae)s 7 35 ~ 44 parts
Radix Mori 32 ~ 41 parts of Herba Sarcandraes 29 ~ 39 parts of Herba Anagallidis Arvensiss 22 ~ 29 portions of Radix salaciae prinoidiss 14 ~ 24 parts.
3. a kind of medicine for the treatment of cerebral hemorrhage according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 69 ~ 74 parts of Radix Laporteae Macrostachyaes 64 ~ 70 portions of Herba Hyperici Sampsoniis 59 ~ 69 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 57 ~ 65 parts
Herba pegani harmalae 54 ~ 64 parts of Folium Craibiodendri Yunnanensiss 51 ~ 59 parts of Flos Wikstroemiae Dolichanthaes 49 ~ 59 parts of Folium et Cacumen Viburni Sargentii 47 ~ 54 parts
Herba Cymbopogonis Citrari 44 ~ 49 parts of Daphne giraldii Nitsche 42 ~ 48 parts of Radix Cudraniaes 39 ~ 44 portions of Semen Hoveniae (Fructus Hoveniae)s 7 38 ~ 41 parts
Radix Mori 34 ~ 39 parts of Herba Sarcandraes 32 ~ 34 parts of Herba Anagallidis Arvensiss 24 ~ 26 portions of Radix salaciae prinoidiss 17 ~ 19 parts.
4. a kind of medicine for the treatment of cerebral hemorrhage according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Caulis Benincasae 72 parts of Radix Laporteae Macrostachyaes 67 portions of Herba Hyperici Sampsoniis 64 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 62 parts
Herba pegani harmalae 59 parts of Folium Craibiodendri Yunnanensiss 55 parts of Flos Wikstroemiae Dolichanthaes 54 parts of Folium et Cacumen Viburni Sargentii 50 parts
Herba Cymbopogonis Citrari 47 parts of Daphne giraldii Nitsche 45 parts of Radix Cudraniaes 42 portions of Semen Hoveniae (Fructus Hoveniae)s 7 39 parts
Radix Mori 37 parts of Herba Sarcandraes 33 parts of Herba Anagallidis Arvensiss 25 portions of Radix salaciae prinoidiss 18 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of cerebral hemorrhage, it is characterized in that: comprise following processing step:
(1) Herba Hyperici Sampsonii, Herba pegani harmalae, Flos Wikstroemiae Dolichanthae, Herba Cymbopogonis Citrari, Daphne giraldii Nitsche, Radix Cudraniae, Radix Mori and Herba Sarcandrae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Folium Craibiodendri Yunnanensis and Folium et Cacumen Viburni Sargentii are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(3) Caulis Benincasae, Caulis fici pumilae (Fructus Fici Pumilae) and Herba Anagallidis Arvensis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Radix Laporteae Macrostachyae, Semen Hoveniae (Fructus Hoveniae) seven and Radix salaciae prinoidis are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.18, for subsequent use;
(5) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), add adjuvant, make tablet, obtain the medicine of described treatment cerebral hemorrhage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310444677.XA CN103463500B (en) | 2013-09-25 | 2013-09-25 | Medicament for treating cerebral hemorrhage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310444677.XA CN103463500B (en) | 2013-09-25 | 2013-09-25 | Medicament for treating cerebral hemorrhage |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103463500A CN103463500A (en) | 2013-12-25 |
| CN103463500B true CN103463500B (en) | 2014-12-31 |
Family
ID=49788692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310444677.XA Expired - Fee Related CN103463500B (en) | 2013-09-25 | 2013-09-25 | Medicament for treating cerebral hemorrhage |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103463500B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104288549A (en) * | 2014-09-26 | 2015-01-21 | 朱晓岩 | Traditional Chinese medicine formula for treating cerebral hemorrhage |
| CN104306601A (en) * | 2014-09-29 | 2015-01-28 | 张波 | Traditional Chinese medicine formula for treating cerebral hemorrhage |
| CN105030919A (en) * | 2015-07-02 | 2015-11-11 | 王厚中 | Medicinal composition for treating cerebral hemorrhage |
| CN105381064A (en) * | 2015-11-16 | 2016-03-09 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for treating cerebral hemorrhage |
| CN105456534A (en) * | 2015-12-29 | 2016-04-06 | 青岛昌安达药业有限公司 | Traditional Chinese medicine preparation for treating cerebral hemorrhage |
| CN105560621A (en) * | 2015-12-29 | 2016-05-11 | 青岛昌安达药业有限公司 | Traditional Chinese medicine composition for treating cerebral hemorrhage |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100384464C (en) * | 2006-08-14 | 2008-04-30 | 黄超权 | Medicine for treating cerebral hemorrhage |
-
2013
- 2013-09-25 CN CN201310444677.XA patent/CN103463500B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN103463500A (en) | 2013-12-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103463500B (en) | Medicament for treating cerebral hemorrhage | |
| CN104940727A (en) | Paste for treating rhinitis and preparation method thereof | |
| CN102631413A (en) | Chinese medicinal composition for treating acne | |
| CN105687409A (en) | Stone needle mud moxibustion and method for preparing same | |
| CN104524208A (en) | Medicament for treatment of sciatica and preparation method | |
| CN104383053B (en) | Traditional Chinese medicine preparation for treating urinary tract infection and production method of traditional Chinese medicine preparation | |
| CN103920046A (en) | Medicine for treating cystitis and preparation method thereof | |
| CN103432485A (en) | Chinese medicinal preparation for treating urinary calculus and preparation method | |
| CN104547384A (en) | Oral liquid for treating paraquat poisoning and preparation method of oral liquid | |
| CN103623335B (en) | A kind of Chinese medicine preparation for the treatment of rhinitis | |
| CN105079721A (en) | Traditional Chinese medicine composition for treating osteoarthritis and preparing method thereof | |
| CN104147295A (en) | Traditional Chinese medicine agentia for treating diarrhea | |
| CN104225256A (en) | Chinese medicine for treating fire toxin invagination type burning and preparation method | |
| CN103845583B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis | |
| CN103961578A (en) | Traditional Chinese medicine medicinal liquor for treating neurasthenia | |
| CN110496200A (en) | It is a kind of to treat phthisical Chinese medicine composition and its preparation method and application | |
| CN107335034A (en) | A kind of external medicine composition for treating leucoderma and its application | |
| CN105709176A (en) | Traditional Chinese medicine composition for treating heart blood stasis type palpitation and preparation method thereof | |
| CN106237303A (en) | The preparation method of rehabilitation Chinese medicine composition after a kind of adjuvant therapy Radiotherapy chemotherapy | |
| CN105106590A (en) | Medicine for treating allergic rhinitis | |
| CN105999200A (en) | Traditional Chinese medicine preparation for treating uremia and preparation method thereof | |
| CN104547635A (en) | Traditional Chinese medicine capsule for treating serious hepatitis and preparation method of traditional Chinese medicine capsule | |
| CN105560753A (en) | Medicine for curing scapulohumeral periarthritis and preparing method | |
| CN105362786A (en) | Traditional Chinese medicine capsules for treating gall-stone and preparation method thereof | |
| CN104645242A (en) | Plaster for treating rheumatic bone diseases |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141231 Termination date: 20150925 |
|
| EXPY | Termination of patent right or utility model |