CN102669003B - Resistance training and hindlimb muscular strength testing device for rats - Google Patents
Resistance training and hindlimb muscular strength testing device for rats Download PDFInfo
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- CN102669003B CN102669003B CN 201210060282 CN201210060282A CN102669003B CN 102669003 B CN102669003 B CN 102669003B CN 201210060282 CN201210060282 CN 201210060282 CN 201210060282 A CN201210060282 A CN 201210060282A CN 102669003 B CN102669003 B CN 102669003B
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- 210000003141 lower extremity Anatomy 0.000 title claims abstract description 19
- 238000012360 testing method Methods 0.000 title claims abstract description 12
- 241000700159 Rattus Species 0.000 title abstract description 45
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- 230000000638 stimulation Effects 0.000 claims abstract description 9
- 210000003205 muscle Anatomy 0.000 claims abstract description 8
- 238000002474 experimental method Methods 0.000 claims abstract description 7
- 238000005259 measurement Methods 0.000 claims abstract 3
- 210000001364 upper extremity Anatomy 0.000 claims description 3
- 230000003287 optical effect Effects 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 230000001960 triggered effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 7
- 241001465754 Metazoa Species 0.000 abstract description 2
- 230000005611 electricity Effects 0.000 abstract description 2
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 6
- 241001417092 Macrouridae Species 0.000 description 4
- 235000009233 Stachytarpheta cayennensis Nutrition 0.000 description 4
- 230000008485 antagonism Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000011810 insulating material Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 206010002027 Amyotrophy Diseases 0.000 description 1
- 206010065687 Bone loss Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000010891 electric arc Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000003194 forelimb Anatomy 0.000 description 1
- 238000005424 photoluminescence Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
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Abstract
本发明属于动物实验技术领域，特别涉及一种大鼠生理实验装置。其技术方案是：一种大鼠抗阻锻炼和后肢肌肉力量测试装置，其特征是：它包括：抗阻力锻炼装置，光刺激器(7)，电刺激器(16)，控制器(15)，测量记录装置(17)。本发明通过光刺激和电刺激结合使大鼠建立对光和电的反射，使大鼠举起一定的重量，通过改变负载重量达到锻炼或测试的目的，还可以进行大鼠后肢力量的评价，且实验过程操作简单方便。
The invention belongs to the technical field of animal experiments, in particular to a rat physiological experiment device. Its technical scheme is: a rat resistance exercise and hindlimb muscle strength testing device, characterized in that: it includes: resistance exercise device, light stimulator (7), electric stimulator (16), controller (15) , measurement recording device (17). The present invention enables the rats to establish light and electricity reflections through the combination of light stimulation and electrical stimulation, so that the rats can lift a certain weight, and achieve the purpose of exercise or testing by changing the load weight, and can also evaluate the strength of the hind limbs of the rats. And the operation of the experiment process is simple and convenient.
Description
Technical field
The invention belongs to the animal experiment technique field, particularly a kind of rat Physiological Experiment device.
Background technology
Very ripe to utilizing rat to carry out the relevant research of road-work, but when utilizing rat to carry out anti-resistance to temper correlative study, temper model and make research be subjected to very big restriction owing to lack corresponding anti-resistance.In aerospace medicine, it is the weightless amyotrophy that causes of antagonism and important safeguard procedures of bone loss that resistive drag force is taken exercise, after ground antagonism resistance exercise is carried out fully, could use at space, therefore be badly in need of setting up a kind of rat anti resistance exercise model so that study.The anti-resistance of the rat hindlimb that domestic and foreign literature is reported is tempered model and mainly contained: 1. utilize food-induced rat to take exercise, this method is difficult to improve the exercise load of rat; 2. utilize the electric arc stimulation in rats to take exercise, this method is mainly tempered musculus flexor; 3. utilize electricity or contact stimulus rat to temper this method complex operation.At present the evaluation of rat muscle strength had only method of testing to the rat forelimb performance grip strength, also not to the method for testing of hind leg strength.
Summary of the invention
The objective of the invention is: provide a kind of and can carry out rat anti resistance exercise and the test of hind leg strength, and device simple to operation.
Technical scheme of the present invention is: a kind of rat anti resistance is taken exercise and hindlimb muscle strength testing arrangement, and it comprises: resistive drag force exercising apparatus, photic stimulator, egersimeter, controller, surveying record device;
Described resistive drag force exercising apparatus comprises: upper surface is the pedestal of conductive layer; Vertically-arranged adopts transparent, insulating materials at described pedestal middle part, is used for holding the cylindric Laboratory Module of rat, and its underpart is provided with the breach of drawing rat tails; Be arranged in the described Laboratory Module and coaxial inner core with it, described inner core can upwards be promoted and freely fallen after rise by the rat upper limbs, and its top is provided with the hole that rat head is stretched out; Regulate described inner core axial location to adapt to the adjusting device of rat height; Be applied to the adjustable load of weight on the described inner core; The feeler lever that the described inner core of companion moves up and down; By the travel switch that described feeler lever triggers, when described feeler lever rose to predetermined altitude, described travel switch sent the signal that rat is finished the weight lifting action; Be arranged on described Laboratory Module bottom, experience rat hindlimb and pedal the pressure sensor of stretching strength;
Described photic stimulator is controlled by described controller, sends the light stimulation signal to rat;
Described egersimeter is controlled by described controller, by being connected to two electrodes of described pedestal upper surface conductive layer and rat tails, sends electrical stimulation signal to rat;
Described controller storage experimental arrangement is controlled described photic stimulator and described egersimeter is worked chronologically;
Described surveying record device receives and records the signal that rat that described travel switch sends is finished the weight lifting action, and the rat hindlimb of described pressure sensor output is pedaled and stretched the strength signal.
The present invention sets up to light and electric reflection rat by light stimulus and electro photoluminescence combination, make rat lift certain weight, reach the purpose of taking exercise or testing by changing load weight, can also carry out the evaluation of rat hindlimb strength, and experimentation is simple to operation.
Description of drawings
Fig. 1 is cutaway view of the present invention;
Fig. 2 is three-dimensional structure schematic diagram of the present invention;
Fig. 3 is signal transitive relation block diagram of the present invention.
Embodiment
Embodiment 1: referring to each accompanying drawing, a kind of rat anti resistance is taken exercise and hindlimb muscle strength testing arrangement, and it is characterized in that: it comprises: resistive drag force exercising apparatus, photic stimulator 7, egersimeter 16, controller 15, surveying record device 17;
Described resistive drag force exercising apparatus comprises: upper surface is the pedestal 1 of conductive layer; Vertically-arranged adopts transparent, insulating materials at described pedestal 1 middle part, is used for holding the cylindric Laboratory Module 2 of rat, and its underpart is provided with the breach 9 of drawing rat tails; Be arranged in the described Laboratory Module 2 and coaxial inner core 4 with it, described inner core 4 can upwards be promoted and freely fallen after rise by the rat upper limbs, and its top is provided with the hole 11 that rat head is stretched out; Regulate the adjusting device 8 of described inner core 4 axial locations to adapt to the rat height; Be applied to the adjustable load 6 of weight on the described inner core 4; The feeler lever 5 that the described inner core 4 of companion moves up and down; By the travel switch 3 that described feeler lever 5 triggers, when described feeler lever 5 rose to predetermined altitude, described travel switch 3 sent the signal that rat is finished the weight lifting action; Be arranged on described Laboratory Module 2 bottoms, experience rat hindlimb and pedal the pressure sensor 10 of stretching strength;
Described photic stimulator 7 sends the light stimulation signal by described controller 15 controls to rat;
Described egersimeter 16 by being connected to two electrodes of described pedestal 1 top surface conductive layers and rat tails, sends electrical stimulation signal to rat by described controller 15 controls;
Described controller 15 storage experimental arrangements are controlled described photic stimulator 7 and described egersimeter 16 and are worked chronologically;
Described surveying record device 17 receives and records the signal that rat that described travel switch 3 sends is finished the weight lifting action, and the rat hindlimb of described pressure sensor 10 outputs is pedaled and stretched the strength signal.
Embodiment 2: 1 described rat anti resistance is taken exercise and hindlimb muscle strength testing arrangement as embodiment, and it is characterized in that: described controller 15 is controlled the described photic stimulator 7 of many covers, described egersimeter 16 simultaneously, to carry out the multichannel experiment simultaneously.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 201210060282 CN102669003B (en) | 2012-03-09 | 2012-03-09 | Resistance training and hindlimb muscular strength testing device for rats |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201210060282 CN102669003B (en) | 2012-03-09 | 2012-03-09 | Resistance training and hindlimb muscular strength testing device for rats |
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| CN102669003A CN102669003A (en) | 2012-09-19 |
| CN102669003B true CN102669003B (en) | 2013-08-28 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105684929B (en) * | 2016-01-19 | 2019-01-01 | 华东师范大学 | A kind of multi-functional work against resistance device |
| CN108784722B (en) * | 2018-07-03 | 2021-02-02 | 广东医诺生物科技有限公司 | Muscle strength testing device for animals |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1160562A1 (en) * | 2000-05-31 | 2001-12-05 | Universitair Bedrijvencentrum Antwerpen (UBCA) | Method and apparatus for the detection of a hidden element exuding a vapor |
| US6347603B1 (en) * | 1999-02-09 | 2002-02-19 | H. Victor Felger | Animal exercising and rehabilitation equipment |
| FR2833135A1 (en) * | 2001-12-10 | 2003-06-13 | Lacme | Training control for dog has high frequency emitter carried on perimeter fence to send signal to receiver on animal which produces mild electric shock |
| CN101703007A (en) * | 2008-06-06 | 2010-05-12 | 北京航空航天大学 | Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat |
| CN201577398U (en) * | 2009-10-20 | 2010-09-15 | 江苏省人民医院 | A walking training device for rats with spinal cord injury |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1735048A4 (en) * | 2004-04-06 | 2008-03-26 | John K Chapin | Teleoperation of a freely roaming animal through brain stimulation |
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2012
- 2012-03-09 CN CN 201210060282 patent/CN102669003B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6347603B1 (en) * | 1999-02-09 | 2002-02-19 | H. Victor Felger | Animal exercising and rehabilitation equipment |
| EP1160562A1 (en) * | 2000-05-31 | 2001-12-05 | Universitair Bedrijvencentrum Antwerpen (UBCA) | Method and apparatus for the detection of a hidden element exuding a vapor |
| FR2833135A1 (en) * | 2001-12-10 | 2003-06-13 | Lacme | Training control for dog has high frequency emitter carried on perimeter fence to send signal to receiver on animal which produces mild electric shock |
| CN101703007A (en) * | 2008-06-06 | 2010-05-12 | 北京航空航天大学 | Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat |
| CN201577398U (en) * | 2009-10-20 | 2010-09-15 | 江苏省人民医院 | A walking training device for rats with spinal cord injury |
Non-Patent Citations (10)
| Title |
|---|
| A weight-lifting exercise model for inducing hypertrophy in the hindlimb muscles of rats;Tokai u niv.et al;《Medicine and science in sports and exercise 》;19921231;第24卷(第8期);第881-886页 * |
| Control and Quantization of Voluntary Weight-Lifting Performance of Rats;Oliver Wirth et al;《Journal of Applied Physiology》;20030328;第95卷(第1期);第1-33页 * |
| Effects of Resistance Training on Ventricular Function and Hypertrophy in a Rat Model;Valério Garrone Barauna et al;《Clin Med Res》;20070630;第5卷(第2期);第114-120页 * |
| Oliver Wirth et al.Control and Quantization of Voluntary Weight-Lifting Performance of Rats.《Journal of Applied Physiology》.2003,第95卷(第1期),第1-33页. |
| Tokai u niv.et al.A weight-lifting exercise model for inducing hypertrophy in the hindlimb muscles of rats.《Medicine and science in sports and exercise 》.1992,第24卷(第8期),第881-886页. |
| Valério Garrone Barauna et al.Effects of Resistance Training on Ventricular Function and Hypertrophy in a Rat Model.《Clin Med Res》.2007,第5卷(第2期),第114-120页. |
| 抗阻力锻炼对8周尾吊大鼠骨丢失的对抗作用;李志利等;《航天医学与医学工程》;20110228;第24卷(第1期);第5-8页 * |
| 李志利等.抗阻力锻炼对8周尾吊大鼠骨丢失的对抗作用.《航天医学与医学工程》.2011,第24卷(第1期),第5-8页. |
| 李志利等.长期失重生理效应体育锻炼防护措施研究进展.《载人航天》.2011,(第1期),第24-27页. |
| 长期失重生理效应体育锻炼防护措施研究进展;李志利等;《载人航天》;20110131(第1期);第24-27页 * |
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