CL2012000389A1 - Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others. - Google Patents

Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others.

Info

Publication number
CL2012000389A1
CL2012000389A1 CL2012000389A CL2012000389A CL2012000389A1 CL 2012000389 A1 CL2012000389 A1 CL 2012000389A1 CL 2012000389 A CL2012000389 A CL 2012000389A CL 2012000389 A CL2012000389 A CL 2012000389A CL 2012000389 A1 CL2012000389 A1 CL 2012000389A1
Authority
CL
Chile
Prior art keywords
heart failure
dysfunction
arrhythmia
pyridin
indole
Prior art date
Application number
CL2012000389A
Other languages
Spanish (es)
Inventor
Qi Ying Hu
Julien Papillon
Christopher Adams
Leslie Wighton Mcquire
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to CL2012000389A priority Critical patent/CL2012000389A1/en
Publication of CL2012000389A1 publication Critical patent/CL2012000389A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compuestos derivados de 2-piridin-3il-indol, inhibidores de la aldosterona sintasa; composición farmacéutica; y su uso en enfermedades cardiovasculars tales como hipertensión, insuficiencia cardíaca, insuficiencia cardíaca congestiva, arritmia, disfunción diastólica de ventrículo izquierdo y disfunción sistólica, entre otras.Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others.

CL2012000389A 2012-02-14 2012-02-14 Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others. CL2012000389A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CL2012000389A CL2012000389A1 (en) 2012-02-14 2012-02-14 Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2012000389A CL2012000389A1 (en) 2012-02-14 2012-02-14 Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others.

Publications (1)

Publication Number Publication Date
CL2012000389A1 true CL2012000389A1 (en) 2012-09-14

Family

ID=69590388

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012000389A CL2012000389A1 (en) 2012-02-14 2012-02-14 Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others.

Country Status (1)

Country Link
CL (1) CL2012000389A1 (en)

Similar Documents

Publication Publication Date Title
CL2014003031A1 (en) Compounds derived from bicyclic substituted uracil; preparation procedure; pharmaceutical composition; use to treat and / or prevent heart failure, pulmonary hypertension, epoc, asthma, nephropathy, among others.
CL2014003121A1 (en) Liquid formulation comprising propylene glycol and an inodilator, an angiotensin converting enzyme inhibitor or a combination of both; process to prepare it; kit; and method of treatment of heart disease and / or hypertension.
DOP2014000170A (en) IMIDAZOPIRROLIDINONA COMPOUNDS
CL2008000690A1 (en) COMPOUNDS DERIVED FROM INDOL-3-PROPIONIC ACID; PHARMACEUTICAL COMPOSITION; AND USE IN THE TREATMENT OF DISEASES SUCH AS HYPERLIPIDEMIA, HYPERTENSION; AMONG OTHER.
EA201300669A1 (en) SUBSTITUTED 1-BENZYL CYCLOALKYL CARBONIC ACIDS AND THEIR APPLICATION
IL237021B (en) Pharmaceutical composition for treatment of pulmonary arterial hypertension with mesenchymal stem cells
CL2014001779A1 (en) Compounds derived from substituted fused pyrimidines and triazines; preparation procedure; Pharmaceutical composition and its use in the treatment and / or prevention of heart failure, angina pectoris, hypertension, among other diseases.
EA201791717A1 (en) STABLE WATER COMPOSITIONS ADALIMUMAB
EA201590931A1 (en) HETEROCYCLIC SUBSTITUTED DERIVATIVES 2-AMINO-HINAZOLINE FOR THE TREATMENT OF VIRAL INFECTIONS
CL2007002689A1 (en) COMPOUNDS DERIVED FROM PIPERIDIN-1-CARBOXAMIDA, INHIBITORS OF THE RENINE; INTERMEDIARY COMPOUNDS; PHARMACEUTICAL COMPOSITION; AND USE IN THE TREATMENT OF DISEASES SUCH AS HYPERTENSION, CARDIAC INSUFFICIENCY, CARDIAC FIBROSIS, AMONG OTHERS.
CO6761351A2 (en) Polypeptides that bind to cxcr2
EA201992133A1 (en) PIPERIDINO-PYRIMIDINE DERIVATIVES FOR TREATMENT OF VIRAL INFECTIONS
UA109464C2 (en) SPIROOXINDOL ANTAGONISTS MDM2
MX381729B (en) SPIRODIAMINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS.
MX347734B (en) S100a4 antibodies and therapeutic uses thereof.
ES2543850R2 (en) Use of SOD mimetic metal complexes as food agents and as cosmetics
EA201270256A1 (en) DERIVATIVES OF T1-SUBSTITUTED 5-FLUOR-2-OXOPYRIMIDINON-1 (2H) -KARBOXAMID
MX367393B (en) ANTIFUNGAL COMPOSITIONS FOR THE TREATMENT OF SKIN and NAILS.
EA201692518A2 (en) METHODS TO IMPROVE MYOCARDIAL PERFORMANCE IN PATIENTS AFTER FONTENE OPERATION USING UDENAFIL COMPOSITIONS
CL2014001323A1 (en) Compounds derived from 3-phenyl-isoquinolin-1 (2h) -one, parp-1 inhibitors; preparation procedure; pharmaceutical composition; and use in the treatment of cancer.
CL2013001445A1 (en) Compounds derived from diphenylamine; Pharmaceutical composition and use in the treatment of inflammatory diseases, such as cancer.
UA115523C2 (en) Solid state forms of macrocyclic kinase inhibitors
DOP2013000182A (en) CATEPSIN C INHIBITORS
CL2012000389A1 (en) Compounds derived from 2-pyridin-3yl-indole, inhibitors of aldosterone synthase; pharmaceutical composition; and its use in cardiovascular diseases such as hypertension, heart failure, congestive heart failure, arrhythmia, left ventricular diastolic dysfunction and systolic dysfunction, among others.
CL2013003536A1 (en) Compounds derived from 4-phenyl indazole and 4-phenyl-cyclopentapyrazole, aldosterone synthase inhibitors; pharmaceutical composition that includes them; and its use in the treatment of kidney diseases, such as chronic kidney disease and diabetic nephropathy.