Papers by Muhammad Ismail
Journal of Medicinal Plants Research, 2012
The study was carried out to screen the crude methanolic extract (Me. Ext) of Pistacia integerrim... more The study was carried out to screen the crude methanolic extract (Me. Ext) of Pistacia integerrima bark for anti gastrointestinal (GIT) motility and analgesic activities. Toxicological study was also conducted for safety profile of the bark. Balb-C mice of either sex weighing 25 to 35 g (n=6) were used as experimental animal. The Me. Ext was safe at a dose of 1000 mgkg-1 body weight (b.w), however at a dose of 1500 mgkg-1 b.w it caused 66.6% death of experimental mice. Me. Ext at a dose of 50 mgkg-1 (35.20±15.22% inhibition) and 100 mgkg-1 (38.89±9.28% inhibition) significantly (p<0.05) reduced the acetic acid induced writhing response in mice indicating significant antinociceptive effect compared to control group. The Extract at a dose of 100 mgkg-1 (28.93±6.98% inhibition) and atropine sulphate 2.5 mgkg-1 (42.93±0.47% inhibition) significantly (p<0.05) reduced the GIT motility, assessed by charcoal propulsion test. No significant difference was observed between control and Me. Ext at a dose of 50 mgkg-1. These findings encourage the P. integerrima bark for its good pharmacological potentials. In addition the study also provides a scientific justifications to some of its tradititional uses.
African Journal of …, 2012
Allergic diseases are fairly common in all parts of the world and involve all ethnic groups with ... more Allergic diseases are fairly common in all parts of the world and involve all ethnic groups with bronchial asthma, allergic rhinitis, conjunctivitis and eczema being the commonest manifestations. Despite our efforts, their incidence is on an escalating path. The use of herbal remedies and standardized extracts for treatment of allergy and other diseases has been gaining momentum in recent years. The qualitative and quantitative determination of phyto-chemicals and assessment of the anti-allergic and antiinflammatory activities using aqueous and organic extracts of different plant parts (root, stem and leaves) of Mentha arvensis in animals showed that all parts of M. arvensis (specifically, leaves) are rich source of secondary phytoconstituents, which impart their therapeutic effects against allergic and inflammatory diseases. These results support the claim about the use of this herb in folk medicines.
academicjournals.org
Proximate composition and levels of metals in four commonly consumed species, Sonchus eruca, Meli... more Proximate composition and levels of metals in four commonly consumed species, Sonchus eruca, Melia azadirchta, Withania coagulans and Fagonia indica, were investigated for the first time. Ash, carbohydrate, protein, fiber, fat and moisture were arranged on dry basis, while Cu, Pb, Co, Cd, Fe, Cr, Mg and Na were also investigated in metal analysis using association of official analytical chemists (AOAC) methods and atomic absorption spectrometric techniques. However, M. azadirachta was found to be rich in fiber content and energy values. The results of metal analysis showed that M. azadirachta had the highest concentrations of the metals like Cu, Mn, Cr and Fe while S. eruca contain higher concentration of Na as compared to other three species.
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Papers by Muhammad Ismail