The PREDICT() macros are supposed to speed dispatch on platforms without computed gotos (i.e. Windows).
However the "predictions" are nothing like the actual behavior observed, especially with PEP 659.

We might want to insert something like the PREDICT macros automatically, but the manually inserted ones are useless, or worse, and should be removed.

Linked PRs

• GH-104610: Remove the use of PREDICT macros. #104651
• gh-104610: Stop looking for PREDICT() in the cases generator #105459