The FT4222H is a High/Full Speed USB2.0-to-Quad SPI/I2C device controller. This project provides (incomplete) python binding to LibFT4222 (user guide). It provides a similar api than LibFT4222 does.
The complete documentation can be found here
import ft4222
import ft4222.I2CMaster
# list devices
nbDev = ft4222.createDeviceInfoList()
for i in range(nbDev):
print(ft4222.getDeviceInfoDetail(i, False))
# open device with default description 'FT4222 A'
dev = ft4222.openByDescription('FT4222 A')
# do a i2c transfers where full control is required
slave = 1 # address
# read one byte, don't stop
data = dev.i2cMaster_ReadEx(slave, ft4222.I2CMaster.Flag.REPEATED_START, 1)[0]
# read another 5 bytes
data += dev.i2cMaster_ReadEx(slave, ft4222.I2CMaster.Flag.NONE, 5)
# another byte, than stop
data += dev.i2cMaster_ReadEx(slave, ft4222.I2CMaster.Flag.STOP, 1)