HEADER GENE REGULATION/DNA 01-MAR-02 1J59

TITLE CATABOLITE GENE ACTIVATOR PROTEIN (CAP)/DNA COMPLEX +

TITLE 2 ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE

COMPND MOL_ID: 1;

COMPND 2 MOLECULE: 5'-D(*GP*CP*GP*AP*AP*AP*AP*GP*TP*GP*TP*GP*AP*C)-

COMPND 3 3';

COMPND 4 CHAIN: C, E;

COMPND 5 ENGINEERED: YES;

COMPND 6 MOL_ID: 2;

COMPND 7 MOLECULE: 5'-

COMPND 8 D(*AP*TP*AP*TP*GP*TP*CP*AP*CP*AP*CP*TP*TP*TP*TP*CP*G )-3';

COMPND 9 CHAIN: D, F;

COMPND 10 ENGINEERED: YES;

COMPND 11 MOL_ID: 3;

COMPND 12 MOLECULE: CATABOLITE GENE ACTIVATOR PROTEIN (CAP);

COMPND 13 CHAIN: A, B;

COMPND 14 ENGINEERED: YES

SOURCE MOL_ID: 1;

SOURCE 2 SYNTHETIC: YES;

SOURCE 3 MOL_ID: 2;

SOURCE 4 SYNTHETIC: YES;

SOURCE 5 MOL_ID: 3;

SOURCE 6 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI;

SOURCE 7 ORGANISM_TAXID: 562;

SOURCE 8 EXPRESSION_SYSTEM: ESCHERICHIA COLI;

SOURCE 9 EXPRESSION_SYSTEM_TAXID: 562

KEYWDS PROTEIN-DNA COMPLEX, GENE-REGULATORY, GENE REGULATION/DNA

KEYWDS 2 COMPLEX

EXPDTA X-RAY DIFFRACTION

AUTHOR G.PARKINSON,C.WILSON,A.GUNASEKERA,Y.W.EBRIGHT,R.H.EBRIGHT,

AUTHOR 2 H.M.BERMAN

REVDAT 3 24-FEB-09 1J59 1 VERSN

REVDAT 2 01-APR-03 1J59 1 JRNL

REVDAT 1 01-MAR-02 1J59 0

SPRSDE 01-MAR-02 1J59 1BER

JRNL AUTH G.PARKINSON,C.WILSON,A.GUNASEKERA,Y.W.EBRIGHT,

JRNL AUTH 2 R.E.EBRIGHT,H.M.BERMAN

JRNL TITL STRUCTURE OF THE CAP-DNA COMPLEX AT 2.5 ANGSTROMS

JRNL TITL 2 RESOLUTION: A COMPLETE PICTURE OF THE PROTEIN-DNA

JRNL TITL 3 INTERFACE.

JRNL REF J.MOL.BIOL. V. 260 395 1996

JRNL REFN ISSN 0022-2836

JRNL PMID 8757802

JRNL DOI 10.1006/JMBI.1996.0409

REMARK 1

REMARK 2

REMARK 2 RESOLUTION. 2.50 ANGSTROMS.

REMARK 3

REMARK 3 REFINEMENT.

REMARK 3 PROGRAM : X-PLOR

REMARK 3 AUTHORS : BRUNGER

REMARK 3

REMARK 3 DATA USED IN REFINEMENT.

REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.50

REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 10.00

REMARK 3 DATA CUTOFF (SIGMA(F)) : 2.000

REMARK 3 DATA CUTOFF HIGH (ABS(F)) : NULL

REMARK 3 DATA CUTOFF LOW (ABS(F)) : NULL

REMARK 3 COMPLETENESS (WORKING+TEST) (%) : 86.0

REMARK 3 NUMBER OF REFLECTIONS : 23644

REMARK 3

REMARK 3 FIT TO DATA USED IN REFINEMENT.

REMARK 3 CROSS-VALIDATION METHOD : NULL

REMARK 3 FREE R VALUE TEST SET SELECTION : NULL

REMARK 3 R VALUE (WORKING SET) : 0.199

REMARK 3 FREE R VALUE : 0.279

REMARK 3 FREE R VALUE TEST SET SIZE (%) : NULL

REMARK 3 FREE R VALUE TEST SET COUNT : NULL

REMARK 3 ESTIMATED ERROR OF FREE R VALUE : NULL

REMARK 3

REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN.

REMARK 3 TOTAL NUMBER OF BINS USED : NULL

REMARK 3 BIN RESOLUTION RANGE HIGH (A) : NULL

REMARK 3 BIN RESOLUTION RANGE LOW (A) : NULL

REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : NULL

REMARK 3 REFLECTIONS IN BIN (WORKING SET) : NULL

REMARK 3 BIN R VALUE (WORKING SET) : NULL

REMARK 3 BIN FREE R VALUE : NULL

REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : NULL

REMARK 3 BIN FREE R VALUE TEST SET COUNT : NULL

REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : NULL

REMARK 3

REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.

REMARK 3 PROTEIN ATOMS : 3128

REMARK 3 NUCLEIC ACID ATOMS : 1262

REMARK 3 HETEROGEN ATOMS : 42

REMARK 3 SOLVENT ATOMS : 286

REMARK 3

REMARK 3 B VALUES.

REMARK 3 FROM WILSON PLOT (A**2) : NULL

REMARK 3 MEAN B VALUE (OVERALL, A**2) : 30.90

REMARK 3 OVERALL ANISOTROPIC B VALUE.

REMARK 3 B11 (A**2) : NULL

REMARK 3 B22 (A**2) : NULL

REMARK 3 B33 (A**2) : NULL

REMARK 3 B12 (A**2) : NULL

REMARK 3 B13 (A**2) : NULL

REMARK 3 B23 (A**2) : NULL

REMARK 3

REMARK 3 ESTIMATED COORDINATE ERROR.

REMARK 3 ESD FROM LUZZATI PLOT (A) : NULL

REMARK 3 ESD FROM SIGMAA (A) : NULL

REMARK 3 LOW RESOLUTION CUTOFF (A) : NULL

REMARK 3

REMARK 3 CROSS-VALIDATED ESTIMATED COORDINATE ERROR.

REMARK 3 ESD FROM C-V LUZZATI PLOT (A) : NULL

REMARK 3 ESD FROM C-V SIGMAA (A) : NULL

REMARK 3

REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES.

REMARK 3 BOND LENGTHS (A) : 0.017

REMARK 3 BOND ANGLES (DEGREES) : 2.27

REMARK 3 DIHEDRAL ANGLES (DEGREES) : 22.90

REMARK 3 IMPROPER ANGLES (DEGREES) : 1.40

REMARK 3

REMARK 3 ISOTROPIC THERMAL MODEL : NULL

REMARK 3

REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA

REMARK 3 MAIN-CHAIN BOND (A**2) : NULL ; NULL

REMARK 3 MAIN-CHAIN ANGLE (A**2) : NULL ; NULL

REMARK 3 SIDE-CHAIN BOND (A**2) : NULL ; NULL

REMARK 3 SIDE-CHAIN ANGLE (A**2) : NULL ; NULL

REMARK 3

REMARK 3 NCS MODEL : NULL

REMARK 3

REMARK 3 NCS RESTRAINTS. RMS SIGMA/WEIGHT

REMARK 3 GROUP 1 POSITIONAL (A) : NULL ; NULL

REMARK 3 GROUP 1 B-FACTOR (A**2) : NULL ; NULL

REMARK 3

REMARK 3 PARAMETER FILE 1 : NULL

REMARK 3 TOPOLOGY FILE 1 : NULL

REMARK 3

REMARK 3 OTHER REFINEMENT REMARKS: NULL

REMARK 4

REMARK 4 1J59 COMPLIES WITH FORMAT V. 3.15, 01-DEC-08

REMARK 100

REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 01-MAR-02.

REMARK 100 THE RCSB ID CODE IS RCSB001694.

REMARK 200

REMARK 200 EXPERIMENTAL DETAILS

REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION

REMARK 200 DATE OF DATA COLLECTION : 01-NOV-92

REMARK 200 TEMPERATURE (KELVIN) : NULL

REMARK 200 PH : 6.50

REMARK 200 NUMBER OF CRYSTALS USED : NULL

REMARK 200

REMARK 200 SYNCHROTRON (Y/N) : Y

REMARK 200 RADIATION SOURCE : CHESS

REMARK 200 BEAMLINE : F1

REMARK 200 X-RAY GENERATOR MODEL : NULL

REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M

REMARK 200 WAVELENGTH OR RANGE (A) : 0.9100

REMARK 200 MONOCHROMATOR : NULL

REMARK 200 OPTICS : NULL

REMARK 200

REMARK 200 DETECTOR TYPE : IMAGE PLATE

REMARK 200 DETECTOR MANUFACTURER : FUJI

REMARK 200 INTENSITY-INTEGRATION SOFTWARE : PURDUE DATA PROCESSING PACKAGE

REMARK 200 DATA SCALING SOFTWARE : NULL

REMARK 200

REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 23876

REMARK 200 RESOLUTION RANGE HIGH (A) : 2.500

REMARK 200 RESOLUTION RANGE LOW (A) : 30.000

REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL

REMARK 200

REMARK 200 OVERALL.

REMARK 200 COMPLETENESS FOR RANGE (%) : 85.4

REMARK 200 DATA REDUNDANCY : NULL

REMARK 200 R MERGE (I) : 0.11470

REMARK 200 R SYM (I) : NULL

REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 2.0000

REMARK 200

REMARK 200 IN THE HIGHEST RESOLUTION SHELL.

REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL

REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : NULL

REMARK 200 COMPLETENESS FOR SHELL (%) : NULL

REMARK 200 DATA REDUNDANCY IN SHELL : NULL

REMARK 200 R MERGE FOR SHELL (I) : NULL

REMARK 200 R SYM FOR SHELL (I) : NULL

REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL

REMARK 200

REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH

REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL

REMARK 200 SOFTWARE USED: NULL

REMARK 200 STARTING MODEL: NULL

REMARK 200

REMARK 200 REMARK: NULL

REMARK 280

REMARK 280 CRYSTAL

REMARK 280 SOLVENT CONTENT, VS (%): 58.71

REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.50

REMARK 280

REMARK 280 CRYSTALLIZATION CONDITIONS: PH 6.50

REMARK 290

REMARK 290 CRYSTALLOGRAPHIC SYMMETRY

REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 2 2 21

REMARK 290

REMARK 290 SYMOP SYMMETRY

REMARK 290 NNNMMM OPERATOR

REMARK 290 1555 X,Y,Z

REMARK 290 2555 -X,-Y,Z+1/2

REMARK 290 3555 -X,Y,-Z+1/2

REMARK 290 4555 X,-Y,-Z

REMARK 290 5555 X+1/2,Y+1/2,Z

REMARK 290 6555 -X+1/2,-Y+1/2,Z+1/2

REMARK 290 7555 -X+1/2,Y+1/2,-Z+1/2

REMARK 290 8555 X+1/2,-Y+1/2,-Z

REMARK 290

REMARK 290 WHERE NNN -> OPERATOR NUMBER

REMARK 290 MMM -> TRANSLATION VECTOR

REMARK 290

REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS

REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM

REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY

REMARK 290 RELATED MOLECULES.

REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000

REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000

REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000

REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000

REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000

REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 38.03000

REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000

REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 0.00000

REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 38.03000

REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 0.00000

REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000

REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000

REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 68.49500

REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 76.40000

REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 0.00000

REMARK 290 SMTRY1 6 -1.000000 0.000000 0.000000 68.49500

REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 76.40000

REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 38.03000

REMARK 290 SMTRY1 7 -1.000000 0.000000 0.000000 68.49500

REMARK 290 SMTRY2 7 0.000000 1.000000 0.000000 76.40000

REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 38.03000

REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 68.49500

REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 76.40000

REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000

REMARK 290

REMARK 290 REMARK: NULL

REMARK 300

REMARK 300 BIOMOLECULE: 1

REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM

REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN

REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON

REMARK 300 BURIED SURFACE AREA.

REMARK 350

REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN

REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE

REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS

REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND

REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.

REMARK 350

REMARK 350 BIOMOLECULE: 1

REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: HEXAMERIC

REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, D, E, F, A, B

REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000

REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000

REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000

REMARK 465

REMARK 465 MISSING RESIDUES

REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE

REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN

REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)

REMARK 465

REMARK 465 M RES C SSSEQI

REMARK 465 VAL A 1

REMARK 465 LEU A 2

REMARK 465 GLY A 3

REMARK 465 LYS A 4

REMARK 465 PRO A 5

REMARK 465 GLN A 6

REMARK 465 THR A 7

REMARK 465 ASP A 8

REMARK 465 THR A 208

REMARK 465 ARG A 209

REMARK 465 VAL B 1

REMARK 465 LEU B 2

REMARK 465 GLY B 3

REMARK 465 LYS B 4

REMARK 465 PRO B 5

REMARK 465 GLN B 6

REMARK 465 THR B 7

REMARK 465 ASP B 8

REMARK 465 TYR B 206

REMARK 465 GLY B 207

REMARK 465 THR B 208

REMARK 465 ARG B 209

REMARK 500

REMARK 500 GEOMETRY AND STEREOCHEMISTRY

REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT

REMARK 500

REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.

REMARK 500

REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE

REMARK 500 N LYS A 166 O HOH A 720 1.97

REMARK 500 CA GLY B 200 O HOH B 532 2.00

REMARK 500 C ILE A 165 O HOH A 720 2.07

REMARK 500

REMARK 500 REMARK: NULL

REMARK 500

REMARK 500 GEOMETRY AND STEREOCHEMISTRY

REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS

REMARK 500

REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES

REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE

REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN

REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).

REMARK 500

REMARK 500 STANDARD TABLE:

REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)

REMARK 500

REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999

REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996

REMARK 500

REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION

REMARK 500 DG C 3 C6 DG C 3 O6 0.056

REMARK 500 DT F 1 C4 DT F 1 C5 0.056

REMARK 500

REMARK 500 REMARK: NULL

REMARK 500

REMARK 500 GEOMETRY AND STEREOCHEMISTRY

REMARK 500 SUBTOPIC: COVALENT BOND ANGLES

REMARK 500

REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES

REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE

REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN

REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).

REMARK 500

REMARK 500 STANDARD TABLE:

REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)

REMARK 500

REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999

REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996

REMARK 500

REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3

REMARK 500 DG C 3 O3' - P - OP2 ANGL. DEV. = 7.2 DEGREES

REMARK 500 DT C 4 O5' - P - OP2 ANGL. DEV. = -5.5 DEGREES

REMARK 500 DT C 4 O3' - P - OP2 ANGL. DEV. = 8.2 DEGREES

REMARK 500 DG C 5 O3' - P - OP2 ANGL. DEV. = 9.8 DEGREES

REMARK 500 DG D 14 O3' - P - OP2 ANGL. DEV. = 6.9 DEGREES

REMARK 500 DT D 15 O3' - P - OP2 ANGL. DEV. = 8.9 DEGREES

REMARK 500 DT D 22 C5' - C4' - C3' ANGL. DEV. = 10.3 DEGREES

REMARK 500 DT D 23 O5' - P - OP1 ANGL. DEV. = -7.5 DEGREES

REMARK 500 DG E 25 N1 - C6 - O6 ANGL. DEV. = -6.7 DEGREES

REMARK 500 DG E 25 C5 - C6 - O6 ANGL. DEV. = 4.1 DEGREES

REMARK 500 DC E 14 O4' - C1' - N1 ANGL. DEV. = 2.9 DEGREES

REMARK 500 DT F 10 N1 - C1' - C2' ANGL. DEV. = 9.8 DEGREES

REMARK 500 DT F 8 O4' - C1' - N1 ANGL. DEV. = 2.6 DEGREES

REMARK 500 DC F 7 O4' - C1' - N1 ANGL. DEV. = 3.9 DEGREES

REMARK 500 DC F 7 O3' - P - OP2 ANGL. DEV. = 7.2 DEGREES

REMARK 500 DT F -1 O3' - P - OP2 ANGL. DEV. = 7.0 DEGREES

REMARK 500 DG F -4 C3' - C2' - C1' ANGL. DEV. = -5.9 DEGREES

REMARK 500 CYS A 178 CA - CB - SG ANGL. DEV. = 9.6 DEGREES

REMARK 500

REMARK 500 REMARK: NULL

REMARK 500

REMARK 500 GEOMETRY AND STEREOCHEMISTRY

REMARK 500 SUBTOPIC: TORSION ANGLES

REMARK 500

REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:

REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;

REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).

REMARK 500

REMARK 500 STANDARD TABLE:

REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)

REMARK 500

REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-

REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400

REMARK 500

REMARK 500 M RES CSSEQI PSI PHI

REMARK 500 PHE A 14 -70.93 -58.75

REMARK 500 SER A 25 158.81 -47.20

REMARK 500 LYS A 26 0.62 54.93

REMARK 500 GLU A 37 -11.27 -160.15

REMARK 500 GLU A 54 -14.80 -49.09

REMARK 500 LEU A 75 -17.85 -42.52

REMARK 500 GLN A 107 1.71 -58.82

REMARK 500 VAL A 108 -73.94 -110.31

REMARK 500 ASP A 155 55.56 -99.58

REMARK 500 ASN A 194 27.71 80.54

REMARK 500 HIS A 199 35.92 164.21

REMARK 500 VAL A 205 87.55 85.34

REMARK 500 TYR A 206 176.37 39.50

REMARK 500 HIS B 17 3.74 -67.14

REMARK 500 LYS B 26 2.92 86.12

REMARK 500 GLU B 55 34.90 -89.03

REMARK 500 GLU B 77 -34.14 -147.36

REMARK 500 GLU B 78 147.09 61.31

REMARK 500 LEU B 148 -71.44 -79.97

REMARK 500 ALA B 151 60.84 -66.67

REMARK 500 LYS B 152 -54.58 -171.43

REMARK 500 PRO B 154 95.25 -55.79

REMARK 500 ASP B 155 -32.13 -173.31

REMARK 500 THR B 158 92.27 -37.77

REMARK 500 MET B 163 166.15 -48.19

REMARK 500 CYS B 178 -159.04 -153.64

REMARK 500 ARG B 180 -45.87 -24.50

REMARK 500 ARG B 185 -33.20 -39.17

REMARK 500 MET B 189 4.38 -55.14

REMARK 500 ASP B 192 -73.80 -51.78

REMARK 500 GLN B 193 -27.88 -40.00

REMARK 500 ASN B 194 23.95 89.91

REMARK 500 HIS B 199 87.28 176.66

REMARK 500

REMARK 500 REMARK: NULL

REMARK 525

REMARK 525 SOLVENT

REMARK 525

REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT

REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST

REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT

REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE

REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER;

REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE

REMARK 525 NUMBER; I=INSERTION CODE):

REMARK 525

REMARK 525 M RES CSSEQI

REMARK 525 HOH D 475 DISTANCE = 6.11 ANGSTROMS

REMARK 525 HOH B 638 DISTANCE = 6.20 ANGSTROMS

REMARK 525 HOH D 482 DISTANCE = 5.60 ANGSTROMS

REMARK 525 HOH D 524 DISTANCE = 5.44 ANGSTROMS

REMARK 525 HOH E 580 DISTANCE = 6.66 ANGSTROMS

REMARK 525 HOH F 559 DISTANCE = 5.09 ANGSTROMS

REMARK 525 HOH C 636 DISTANCE = 5.26 ANGSTROMS

REMARK 525 HOH D 642 DISTANCE = 5.23 ANGSTROMS

REMARK 525 HOH D 755 DISTANCE = 6.07 ANGSTROMS

REMARK 610

REMARK 610 MISSING HETEROATOM

REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;

REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;

REMARK 610 I=INSERTION CODE):

REMARK 610 M RES C SSEQI

REMARK 610 CMP B 761

REMARK 610 CMP A 762

REMARK 800

REMARK 800 SITE

REMARK 800 SITE_IDENTIFIER: AC1

REMARK 800 EVIDENCE_CODE: SOFTWARE

REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE CMP B 761

REMARK 800 SITE_IDENTIFIER: AC2

REMARK 800 EVIDENCE_CODE: SOFTWARE

REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE CMP A 762

DBREF 1J59 A 1 209 UNP P0ACJ8 CRP_ECOLI 2 210

DBREF 1J59 B 1 209 UNP P0ACJ8 CRP_ECOLI 2 210

DBREF 1J59 C -5 9 PDB 1J59 1J59 -5 9

DBREF 1J59 D 10 26 PDB 1J59 1J59 10 26

DBREF 1J59 E 27 14 PDB 1J59 1J59 27 14

DBREF 1J59 F 13 -4 PDB 1J59 1J59 13 -4

SEQRES 1 C 14 DG DC DG DA DA DA DA DG DT DG DT DG DA

SEQRES 2 C 14 DC

SEQRES 1 D 17 DA DT DA DT DG DT DC DA DC DA DC DT DT

SEQRES 2 D 17 DT DT DC DG

SEQRES 1 E 14 DG DC DG DA DA DA DA DG DT DG DT DG DA

SEQRES 2 E 14 DC

SEQRES 1 F 17 DA DT DA DT DG DT DC DA DC DA DC DT DT

SEQRES 2 F 17 DT DT DC DG

SEQRES 1 A 209 VAL LEU GLY LYS PRO GLN THR ASP PRO THR LEU GLU TRP

SEQRES 2 A 209 PHE LEU SER HIS CYS HIS ILE HIS LYS TYR PRO SER LYS

SEQRES 3 A 209 SER THR LEU ILE HIS GLN GLY GLU LYS ALA GLU THR LEU

SEQRES 4 A 209 TYR TYR ILE VAL LYS GLY SER VAL ALA VAL LEU ILE LYS

SEQRES 5 A 209 ASP GLU GLU GLY LYS GLU MET ILE LEU SER TYR LEU ASN

SEQRES 6 A 209 GLN GLY ASP PHE ILE GLY GLU LEU GLY LEU PHE GLU GLU

SEQRES 7 A 209 GLY GLN GLU ARG SER ALA TRP VAL ARG ALA LYS THR ALA

SEQRES 8 A 209 CYS GLU VAL ALA GLU ILE SER TYR LYS LYS PHE ARG GLN

SEQRES 9 A 209 LEU ILE GLN VAL ASN PRO ASP ILE LEU MET ARG LEU SER

SEQRES 10 A 209 ALA GLN MET ALA ARG ARG LEU GLN VAL THR SER GLU LYS

SEQRES 11 A 209 VAL GLY ASN LEU ALA PHE LEU ASP VAL THR GLY ARG ILE

SEQRES 12 A 209 ALA GLN THR LEU LEU ASN LEU ALA LYS GLN PRO ASP ALA

SEQRES 13 A 209 MET THR HIS PRO ASP GLY MET GLN ILE LYS ILE THR ARG

SEQRES 14 A 209 GLN GLU ILE GLY GLN ILE VAL GLY CYS SER ARG GLU THR

SEQRES 15 A 209 VAL GLY ARG ILE LEU LYS MET LEU GLU ASP GLN ASN LEU

SEQRES 16 A 209 ILE SER ALA HIS GLY LYS THR ILE VAL VAL TYR GLY THR

SEQRES 17 A 209 ARG

SEQRES 1 B 209 VAL LEU GLY LYS PRO GLN THR ASP PRO THR LEU GLU TRP

SEQRES 2 B 209 PHE LEU SER HIS CYS HIS ILE HIS LYS TYR PRO SER LYS

SEQRES 3 B 209 SER THR LEU ILE HIS GLN GLY GLU LYS ALA GLU THR LEU

SEQRES 4 B 209 TYR TYR ILE VAL LYS GLY SER VAL ALA VAL LEU ILE LYS

SEQRES 5 B 209 ASP GLU GLU GLY LYS GLU MET ILE LEU SER TYR LEU ASN

SEQRES 6 B 209 GLN GLY ASP PHE ILE GLY GLU LEU GLY LEU PHE GLU GLU

SEQRES 7 B 209 GLY GLN GLU ARG SER ALA TRP VAL ARG ALA LYS THR ALA

SEQRES 8 B 209 CYS GLU VAL ALA GLU ILE SER TYR LYS LYS PHE ARG GLN

SEQRES 9 B 209 LEU ILE GLN VAL ASN PRO ASP ILE LEU MET ARG LEU SER

SEQRES 10 B 209 ALA GLN MET ALA ARG ARG LEU GLN VAL THR SER GLU LYS

SEQRES 11 B 209 VAL GLY ASN LEU ALA PHE LEU ASP VAL THR GLY ARG ILE

SEQRES 12 B 209 ALA GLN THR LEU LEU ASN LEU ALA LYS GLN PRO ASP ALA

SEQRES 13 B 209 MET THR HIS PRO ASP GLY MET GLN ILE LYS ILE THR ARG

SEQRES 14 B 209 GLN GLU ILE GLY GLN ILE VAL GLY CYS SER ARG GLU THR

SEQRES 15 B 209 VAL GLY ARG ILE LEU LYS MET LEU GLU ASP GLN ASN LEU

SEQRES 16 B 209 ILE SER ALA HIS GLY LYS THR ILE VAL VAL TYR GLY THR

SEQRES 17 B 209 ARG

HET CMP B 761 21

HET CMP A 762 21

HETNAM CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE

HETSYN CMP CYCLIC AMP; CAMP

FORMUL 7 CMP 2(C10 H12 N5 O6 P)

FORMUL 9 HOH *286(H2 O)

HELIX 1 1 THR A 10 HIS A 17 1 8

HELIX 2 2 TYR A 99 ILE A 106 1 8

HELIX 3 3 PRO A 110 PHE A 136 5 27

HELIX 4 4 VAL A 139 LYS A 152 1 14

HELIX 5 5 ARG A 169 VAL A 176 1 8

HELIX 6 6 ARG A 180 ASP A 192 1 13

HELIX 7 7 THR B 10 SER B 16 1 7

HELIX 8 8 GLY B 74 PHE B 76 5 3

HELIX 9 9 TYR B 99 VAL B 108 1 10

HELIX 10 10 PRO B 110 PHE B 136 1 27

HELIX 11 11 VAL B 139 LEU B 150 1 12

HELIX 12 12 ARG B 169 VAL B 176 1 8

HELIX 13 13 ARG B 180 GLU B 191 1 12

SHEET 1 A 3 TRP A 85 ALA A 88 0

SHEET 2 A 3 VAL A 47 LYS A 52 -1 N LEU A 50 O TRP A 85

SHEET 3 A 3 GLU A 58 LEU A 64 -1 N LEU A 64 O VAL A 47

SHEET 1 B 3 MET A 163 LYS A 166 0

SHEET 2 B 3 LYS A 201 VAL A 204 -1 N VAL A 204 O MET A 163

SHEET 3 B 3 ILE A 196 ALA A 198 -1 N SER A 197 O ILE A 203

SHEET 1 C 3 HIS B 19 TYR B 23 0

SHEET 2 C 3 CYS B 92 SER B 98 -1 N GLU B 96 O HIS B 19

SHEET 3 C 3 THR B 38 LYS B 44 -1 N LYS B 44 O GLU B 93

SHEET 1 D 3 TRP B 85 ALA B 88 0

SHEET 2 D 3 SER B 46 LYS B 52 -1 N LEU B 50 O TRP B 85

SHEET 3 D 3 GLU B 58 ASN B 65 -1 N LEU B 64 O VAL B 47

SHEET 1 E 2 ILE B 196 HIS B 199 0

SHEET 2 E 2 LYS B 201 VAL B 204 -1 N ILE B 203 O SER B 197

SHEET 1 F 2 THR A 38 LYS A 44 0

SHEET 2 F 2 GLU A 93 SER A 98 -1 N ILE A 97 O LEU A 39

SITE 1 AC1 10 LEU A 124 SER A 128 VAL B 49 GLY B 71

SITE 2 AC1 10 GLU B 72 LEU B 73 ARG B 82 SER B 83

SITE 3 AC1 10 ALA B 84 THR B 127

SITE 1 AC2 11 ILE A 30 VAL A 49 LEU A 61 GLY A 71

SITE 2 AC2 11 GLU A 72 LEU A 73 ARG A 82 SER A 83

SITE 3 AC2 11 THR A 127 LEU B 124 SER B 128

CRYST1 136.990 152.800 76.060 90.00 90.00 90.00 C 2 2 21 16

ORIGX1 1.000000 0.000000 0.000000 0.00000

ORIGX2 0.000000 1.000000 0.000000 0.00000

ORIGX3 0.000000 0.000000 1.000000 0.00000

SCALE1 0.007299 0.000000 0.000000 0.00000

SCALE2 0.000000 0.006544 0.000000 0.00000

SCALE3 0.000000 0.000000 0.013147 0.00000

ATOM 1 O5' DG C -5 -5.513 61.883 -25.680 1.00 38.64 O

ATOM 2 C5' DG C -5 -4.320 62.508 -25.164 1.00 41.72 C

ATOM 3 C4' DG C -5 -4.328 63.985 -25.475 1.00 38.99 C

ATOM 4 O4' DG C -5 -4.443 64.782 -24.264 1.00 30.81 O

ATOM 5 C3' DG C -5 -3.102 64.474 -26.247 1.00 36.45 C

ATOM 6 O3' DG C -5 -3.629 65.218 -27.360 1.00 46.52 O

ATOM 7 C2' DG C -5 -2.320 65.297 -25.223 1.00 36.24 C

ATOM 8 C1' DG C -5 -3.319 65.650 -24.112 1.00 38.95 C

ATOM 9 N9 DG C -5 -2.861 65.541 -22.717 1.00 36.28 N

ATOM 10 C8 DG C -5 -2.739 64.397 -21.970 1.00 33.98 C

ATOM 11 N7 DG C -5 -2.338 64.624 -20.741 1.00 39.95 N

ATOM 12 C5 DG C -5 -2.185 66.002 -20.669 1.00 35.40 C

ATOM 13 C6 DG C -5 -1.775 66.862 -19.573 1.00 38.15 C

ATOM 14 O6 DG C -5 -1.507 66.565 -18.403 1.00 32.94 O

ATOM 15 N1 DG C -5 -1.712 68.193 -19.962 1.00 38.66 N

ATOM 16 C2 DG C -5 -2.019 68.662 -21.202 1.00 43.52 C

ATOM 17 N2 DG C -5 -1.892 69.982 -21.387 1.00 40.44 N

ATOM 18 N3 DG C -5 -2.423 67.893 -22.212 1.00 46.07 N

ATOM 19 C4 DG C -5 -2.482 66.586 -21.881 1.00 37.80 C

ATOM 20 P DC C -4 -2.672 65.800 -28.514 1.00 43.99 P

ATOM 21 OP1 DC C -4 -3.635 66.486 -29.432 1.00 41.89 O

ATOM 22 OP2 DC C -4 -1.774 64.742 -29.034 1.00 42.54 O

ATOM 23 O5' DC C -4 -1.839 66.949 -27.763 1.00 49.52 O

ATOM 24 C5' DC C -4 -2.502 68.023 -27.042 1.00 39.42 C

ATOM 25 C4' DC C -4 -2.448 69.314 -27.835 1.00 45.05 C

ATOM 26 O4' DC C -4 -2.052 70.421 -26.997 1.00 38.10 O

ATOM 27 C3' DC C -4 -1.383 69.287 -28.922 1.00 48.10 C

ATOM 28 O3' DC C -4 -1.717 70.209 -29.944 1.00 53.24 O

ATOM 29 C2' DC C -4 -0.129 69.756 -28.208 1.00 50.54 C

ATOM 30 C1' DC C -4 -0.629 70.414 -26.930 1.00 46.09 C

ATOM 31 N1 DC C -4 -0.270 69.624 -25.759 1.00 45.78 N

ATOM 32 C2 DC C -4 -0.169 70.270 -24.535 1.00 49.94 C

ATOM 33 O2 DC C -4 -0.365 71.498 -24.495 1.00 55.00 O

ATOM 34 N3 DC C -4 0.137 69.555 -23.425 1.00 45.26 N

ATOM 35 C4 DC C -4 0.342 68.242 -23.523 1.00 45.88 C

ATOM 36 N4 DC C -4 0.631 67.562 -22.396 1.00 39.63 N

ATOM 37 C5 DC C -4 0.257 67.561 -24.780 1.00 47.94 C

ATOM 38 C6 DC C -4 -0.046 68.283 -25.858 1.00 38.54 C

ATOM 39 P DG C -3 -1.047 70.066 -31.388 1.00 48.45 P

ATOM 40 OP1 DG C -3 -2.067 70.399 -32.445 1.00 50.01 O

ATOM 41 OP2 DG C -3 -0.415 68.728 -31.365 1.00 51.07 O

ATOM 42 O5' DG C -3 0.050 71.208 -31.389 1.00 45.60 O

ATOM 43 C5' DG C -3 1.345 70.968 -30.881 1.00 45.65 C

ATOM 44 C4' DG C -3 1.892 72.247 -30.307 1.00 48.82 C

ATOM 45 O4' DG C -3 2.096 72.061 -28.896 1.00 49.02 O

ATOM 46 C3' DG C -3 3.254 72.610 -30.848 1.00 49.88 C

ATOM 47 O3' DG C -3 3.435 74.032 -30.679 1.00 50.46 O

ATOM 48 C2' DG C -3 4.171 71.762 -29.973 1.00 48.77 C

ATOM 49 C1' DG C -3 3.481 71.831 -28.626 1.00 53.28 C

ATOM 50 N9 DG C -3 3.584 70.642 -27.768 1.00 54.83 N

ATOM 51 C8 DG C -3 3.540 69.321 -28.143 1.00 49.73 C

ATOM 52 N7 DG C -3 3.646 68.501 -27.130 1.00 48.47 N

ATOM 53 C5 DG C -3 3.773 69.325 -26.023 1.00 44.64 C

ATOM 54 C6 DG C -3 3.926 69.011 -24.665 1.00 40.91 C

ATOM 55 O6 DG C -3 4.003 67.922 -24.135 1.00 39.80 O

ATOM 56 N1 DG C -3 4.003 70.138 -23.890 1.00 45.45 N

ATOM 57 C2 DG C -3 3.958 71.419 -24.353 1.00 43.65 C

ATOM 58 N2 DG C -3 4.056 72.375 -23.425 1.00 47.81 N

ATOM 59 N3 DG C -3 3.827 71.741 -25.613 1.00 45.65 N

ATOM 60 C4 DG C -3 3.738 70.649 -26.393 1.00 49.55 C

ATOM 61 P DA C -2 4.300 74.860 -31.757 1.00 52.22 P

ATOM 62 OP1 DA C -2 3.369 75.612 -32.671 1.00 48.13 O

ATOM 63 OP2 DA C -2 5.338 73.940 -32.351 1.00 46.12 O

ATOM 64 O5' DA C -2 5.135 75.903 -30.884 1.00 51.19 O

ATOM 65 C5' DA C -2 4.504 76.780 -29.973 1.00 42.96 C

ATOM 66 C4' DA C -2 5.313 76.844 -28.701 1.00 51.90 C

ATOM 67 O4' DA C -2 5.377 75.524 -28.094 1.00 55.00 O

ATOM 68 C3' DA C -2 6.766 77.289 -28.867 1.00 49.76 C

ATOM 69 O3' DA C -2 7.103 78.034 -27.673 1.00 45.65 O

ATOM 70 C2' DA C -2 7.501 75.950 -28.920 1.00 50.32 C

ATOM 71 C1' DA C -2 6.726 75.133 -27.892 1.00 51.61 C

ATOM 72 N9 DA C -2 6.781 73.667 -28.011 1.00 54.31 N

ATOM 73 C8 DA C -2 6.819 72.889 -29.157 1.00 54.67 C

ATOM 74 N7 DA C -2 6.846 71.590 -28.921 1.00 47.83 N

ATOM 75 C5 DA C -2 6.833 71.505 -27.533 1.00 46.09 C

ATOM 76 C6 DA C -2 6.857 70.400 -26.641 1.00 40.88 C

ATOM 77 N6 DA C -2 6.890 69.123 -27.018 1.00 40.41 N

ATOM 78 N1 DA C -2 6.842 70.664 -25.328 1.00 42.95 N

ATOM 79 C2 DA C -2 6.801 71.942 -24.937 1.00 45.27 C

ATOM 80 N3 DA C -2 6.775 73.060 -25.664 1.00 40.58 N

ATOM 81 C4 DA C -2 6.794 72.775 -26.963 1.00 47.40 C

ATOM 82 P DA C -1 8.207 79.196 -27.713 1.00 46.03 P

ATOM 83 OP1 DA C -1 7.595 80.446 -27.189 1.00 40.78 O

ATOM 84 OP2 DA C -1 8.770 79.127 -29.092 1.00 45.36 O

ATOM 85 O5' DA C -1 9.336 78.745 -26.679 1.00 46.41 O

ATOM 86 C5' DA C -1 9.090 78.817 -25.270 1.00 52.50 C

ATOM 87 C4' DA C -1 9.985 77.875 -24.475 1.00 47.09 C

ATOM 88 O4' DA C -1 9.776 76.472 -24.743 1.00 51.83 O

ATOM 89 C3' DA C -1 11.483 78.094 -24.532 1.00 37.18 C

ATOM 90 O3' DA C -1 11.827 78.105 -23.191 1.00 39.85 O

ATOM 91 C2' DA C -1 12.035 76.871 -25.245 1.00 38.58 C

ATOM 92 C1' DA C -1 11.022 75.795 -24.899 1.00 48.80 C

ATOM 93 N9 DA C -1 10.780 74.723 -25.877 1.00 46.32 N

ATOM 94 C8 DA C -1 10.462 74.789 -27.210 1.00 51.01 C

ATOM 95 N7 DA C -1 10.279 73.613 -27.776 1.00 48.57 N

ATOM 96 C5 DA C -1 10.499 72.718 -26.751 1.00 48.85 C

ATOM 97 C6 DA C -1 10.431 71.323 -26.688 1.00 48.01 C

ATOM 98 N6 DA C -1 10.155 70.530 -27.723 1.00 53.37 N

ATOM 99 N1 DA C -1 10.668 70.748 -25.506 1.00 49.06 N

ATOM 100 C2 DA C -1 10.966 71.521 -24.456 1.00 51.75 C

ATOM 101 N3 DA C -1 11.071 72.840 -24.381 1.00 51.23 N

ATOM 102 C4 DA C -1 10.815 73.385 -25.577 1.00 50.45 C

ATOM 103 P DA C 1 13.350 78.050 -22.773 1.00 47.45 P

ATOM 104 OP1 DA C 1 13.469 78.954 -21.582 1.00 45.49 O

ATOM 105 OP2 DA C 1 14.274 78.193 -23.934 1.00 42.50 O

ATOM 106 O5' DA C 1 13.498 76.545 -22.326 1.00 48.52 O

ATOM 107 C5' DA C 1 12.567 75.958 -21.444 1.00 43.66 C

ATOM 108 C4' DA C 1 13.127 74.642 -20.987 1.00 45.75 C

ATOM 109 O4' DA C 1 13.034 73.740 -22.116 1.00 39.86 O

ATOM 110 C3' DA C 1 14.615 74.720 -20.604 1.00 45.30 C

ATOM 111 O3' DA C 1 14.788 74.066 -19.312 1.00 47.29 O

ATOM 112 C2' DA C 1 15.331 74.106 -21.803 1.00 40.69 C

ATOM 113 C1' DA C 1 14.294 73.152 -22.379 1.00 40.17 C

ATOM 114 N9 DA C 1 14.311 72.882 -23.814 1.00 43.03 N

ATOM 115 C8 DA C 1 14.560 73.738 -24.843 1.00 47.38 C

ATOM 116 N7 DA C 1 14.454 73.186 -26.030 1.00 46.14 N

ATOM 117 C5 DA C 1 14.118 71.871 -25.758 1.00 42.97 C

ATOM 118 C6 DA C 1 13.824 70.756 -26.604 1.00 47.73 C

ATOM 119 N6 DA C 1 13.851 70.790 -27.945 1.00 44.81 N

ATOM 120 N1 DA C 1 13.494 69.592 -26.006 1.00 51.72 N

ATOM 121 C2 DA C 1 13.464 69.553 -24.654 1.00 55.00 C

ATOM 122 N3 DA C 1 13.717 70.525 -23.768 1.00 45.64 N

ATOM 123 C4 DA C 1 14.039 71.668 -24.393 1.00 43.59 C

ATOM 124 P DA C 2 16.253 73.696 -18.748 1.00 45.80 P

ATOM 125 OP1 DA C 2 16.183 73.492 -17.271 1.00 44.06 O

ATOM 126 OP2 DA C 2 17.314 74.543 -19.344 1.00 42.72 O

ATOM 127 O5' DA C 2 16.478 72.240 -19.326 1.00 51.30 O

ATOM 128 C5' DA C 2 15.493 71.236 -19.112 1.00 47.61 C

ATOM 129 C4' DA C 2 15.922 69.943 -19.763 1.00 42.19 C

ATOM 130 O4' DA C 2 15.790 70.056 -21.196 1.00 39.05 O

ATOM 131 C3' DA C 2 17.371 69.560 -19.486 1.00 34.23 C

ATOM 132 O3' DA C 2 17.340 68.254 -18.878 1.00 29.13 O

ATOM 133 C2' DA C 2 18.022 69.640 -20.861 1.00 30.35 C

ATOM 134 C1' DA C 2 16.863 69.442 -21.807 1.00 30.17 C

ATOM 135 N9 DA C 2 17.041 70.086 -23.087 1.00 28.16 N

ATOM 136 C8 DA C 2 17.331 71.391 -23.351 1.00 37.58 C

ATOM 137 N7 DA C 2 17.451 71.662 -24.618 1.00 35.88 N

ATOM 138 C5 DA C 2 17.221 70.435 -25.233 1.00 39.40 C

ATOM 139 C6 DA C 2 17.271 70.012 -26.579 1.00 38.39 C

ATOM 140 N6 DA C 2 17.514 70.816 -27.604 1.00 42.42 N

ATOM 141 N1 DA C 2 17.058 68.710 -26.831 1.00 37.24 N

ATOM 142 C2 DA C 2 16.808 67.890 -25.803 1.00 38.70 C

ATOM 143 N3 DA C 2 16.734 68.161 -24.520 1.00 34.87 N

ATOM 144 C4 DA C 2 16.957 69.467 -24.293 1.00 34.26 C

ATOM 145 P DG C 3 18.711 67.431 -18.615 1.00 18.93 P

ATOM 146 OP1 DG C 3 18.258 66.503 -17.501 1.00 17.51 O

ATOM 147 OP2 DG C 3 19.981 68.214 -18.499 1.00 15.92 O

ATOM 148 O5' DG C 3 18.863 66.613 -19.967 1.00 22.62 O

ATOM 149 C5' DG C 3 17.817 65.715 -20.388 1.00 19.89 C

ATOM 150 C4' DG C 3 18.278 64.931 -21.585 1.00 10.77 C

ATOM 151 O4' DG C 3 18.382 65.896 -22.634 1.00 13.32 O

ATOM 152 C3' DG C 3 19.678 64.313 -21.451 1.00 12.75 C

ATOM 153 O3' DG C 3 19.583 62.928 -21.708 1.00 14.83 O

ATOM 154 C2' DG C 3 20.508 65.046 -22.477 1.00 6.00 C

ATOM 155 C1' DG C 3 19.427 65.526 -23.434 1.00 14.49 C

ATOM 156 N9 DG C 3 19.855 66.655 -24.243 1.00 21.27 N

ATOM 157 C8 DG C 3 20.562 67.748 -23.802 1.00 30.68 C

ATOM 158 N7 DG C 3 20.895 68.569 -24.760 1.00 31.53 N

ATOM 159 C5 DG C 3 20.359 67.993 -25.906 1.00 32.34 C

ATOM 160 C6 DG C 3 20.455 68.399 -27.280 1.00 31.35 C

ATOM 161 O6 DG C 3 21.035 69.435 -27.791 1.00 26.87 O

ATOM 162 N1 DG C 3 19.800 67.489 -28.115 1.00 33.43 N

ATOM 163 C2 DG C 3 19.146 66.362 -27.705 1.00 35.48 C

ATOM 164 N2 DG C 3 18.574 65.651 -28.702 1.00 34.59 N

ATOM 165 N3 DG C 3 19.058 65.967 -26.430 1.00 28.62 N

ATOM 166 C4 DG C 3 19.686 66.821 -25.596 1.00 23.64 C

ATOM 167 P DT C 4 20.899 62.044 -21.929 1.00 17.48 P

ATOM 168 OP1 DT C 4 20.504 60.642 -21.676 1.00 28.44 O

ATOM 169 OP2 DT C 4 22.214 62.555 -21.389 1.00 21.50 O

ATOM 170 O5' DT C 4 21.133 62.257 -23.491 1.00 28.24 O

ATOM 171 C5' DT C 4 20.299 61.671 -24.463 1.00 17.17 C

ATOM 172 C4' DT C 4 21.077 61.568 -25.744 1.00 21.82 C

ATOM 173 O4' DT C 4 21.197 62.933 -26.189 1.00 25.33 O

ATOM 174 C3' DT C 4 22.517 61.030 -25.571 1.00 24.78 C

ATOM 175 O3' DT C 4 22.744 59.961 -26.509 1.00 19.15 O

ATOM 176 C2' DT C 4 23.425 62.234 -25.783 1.00 22.80 C

ATOM 177 C1' DT C 4 22.531 63.164 -26.598 1.00 26.79 C

ATOM 178 N1 DT C 4 22.802 64.613 -26.484 1.00 27.98 N

ATOM 179 C2 DT C 4 22.857 65.297 -27.679 1.00 23.63 C

ATOM 180 O2 DT C 4 22.666 64.738 -28.745 1.00 29.11 O

ATOM 181 N3 DT C 4 23.139 66.653 -27.586 1.00 18.52 N

ATOM 182 C4 DT C 4 23.365 67.368 -26.418 1.00 26.60 C

ATOM 183 O4 DT C 4 23.613 68.594 -26.490 1.00 18.40 O

ATOM 184 C5 DT C 4 23.281 66.557 -25.168 1.00 15.09 C

ATOM 185 C7 DT C 4 23.523 67.217 -23.857 1.00 17.01 C

ATOM 186 C6 DT C 4 23.003 65.249 -25.272 1.00 21.89 C

ATOM 187 P DG C 5 24.220 59.323 -26.711 1.00 25.35 P

ATOM 188 OP1 DG C 5 23.806 57.932 -26.932 1.00 24.62 O

ATOM 189 OP2 DG C 5 25.315 59.649 -25.757 1.00 23.48 O

ATOM 190 O5' DG C 5 24.653 59.869 -28.138 1.00 32.80 O

ATOM 191 C5' DG C 5 23.752 59.614 -29.225 1.00 36.50 C

ATOM 192 C4' DG C 5 24.415 59.818 -30.556 1.00 25.94 C

ATOM 193 O4' DG C 5 24.753 61.197 -30.595 1.00 28.89 O

ATOM 194 C3' DG C 5 25.685 59.022 -30.785 1.00 34.63 C

ATOM 195 O3' DG C 5 25.620 58.394 -32.092 1.00 32.43 O

ATOM 196 C2' DG C 5 26.799 60.023 -30.503 1.00 33.78 C

ATOM 197 C1' DG C 5 26.143 61.394 -30.612 1.00 35.99 C

ATOM 198 N9 DG C 5 26.408 62.369 -29.558 1.00 40.06 N

ATOM 199 C8 DG C 5 26.645 62.115 -28.231 1.00 35.11 C

ATOM 200 N7 DG C 5 26.819 63.202 -27.521 1.00 33.83 N

ATOM 201 C5 DG C 5 26.690 64.246 -28.429 1.00 37.23 C

ATOM 202 C6 DG C 5 26.781 65.665 -28.231 1.00 33.12 C

ATOM 203 O6 DG C 5 26.979 66.277 -27.196 1.00 36.14 O

ATOM 204 N1 DG C 5 26.610 66.365 -29.415 1.00 35.63 N

ATOM 205 C2 DG C 5 26.384 65.789 -30.646 1.00 38.08 C

ATOM 206 N2 DG C 5 26.275 66.639 -31.649 1.00 35.21 N

ATOM 207 N3 DG C 5 26.281 64.466 -30.863 1.00 37.93 N

ATOM 208 C4 DG C 5 26.445 63.757 -29.704 1.00 41.91 C

ATOM 209 P DT C 6 26.965 58.071 -32.910 1.00 40.56 P

ATOM 210 OP1 DT C 6 26.564 57.966 -34.310 1.00 35.20 O

ATOM 211 OP2 DT C 6 27.790 56.985 -32.319 1.00 36.00 O

ATOM 212 O5' DT C 6 27.764 59.412 -32.739 1.00 33.05 O

ATOM 213 C5' DT C 6 27.400 60.519 -33.495 1.00 25.39 C

ATOM 214 C4' DT C 6 28.601 60.978 -34.243 1.00 33.42 C

ATOM 215 O4' DT C 6 29.078 62.130 -33.549 1.00 33.86 O

ATOM 216 C3' DT C 6 29.747 59.969 -34.226 1.00 43.29 C

ATOM 217 O3' DT C 6 30.483 60.179 -35.440 1.00 54.14 O

ATOM 218 C2' DT C 6 30.549 60.369 -32.992 1.00 37.21 C

ATOM 219 C1' DT C 6 30.302 61.878 -32.866 1.00 37.56 C

ATOM 220 N1 DT C 6 30.084 62.366 -31.495 1.00 38.76 N

ATOM 221 C2 DT C 6 29.879 63.727 -31.286 1.00 38.07 C

ATOM 222 O2 DT C 6 29.906 64.568 -32.164 1.00 37.79 O

ATOM 223 N3 DT C 6 29.643 64.073 -29.991 1.00 42.06 N

ATOM 224 C4 DT C 6 29.600 63.230 -28.901 1.00 43.79 C

ATOM 225 O4 DT C 6 29.371 63.699 -27.790 1.00 42.64 O

ATOM 226 C5 DT C 6 29.841 61.814 -29.195 1.00 42.21 C

ATOM 227 C7 DT C 6 29.822 60.814 -28.086 1.00 42.65 C

ATOM 228 C6 DT C 6 30.069 61.470 -30.457 1.00 37.01 C

ATOM 229 P DG C 7 31.343 59.002 -36.098 1.00 53.86 P

ATOM 230 OP1 DG C 7 31.126 59.181 -37.584 1.00 47.74 O

ATOM 231 OP2 DG C 7 31.029 57.678 -35.465 1.00 55.00 O

ATOM 232 O5' DG C 7 32.825 59.451 -35.688 1.00 52.23 O

ATOM 233 C5' DG C 7 33.372 60.676 -36.214 1.00 51.25 C

ATOM 234 C4' DG C 7 34.721 61.016 -35.603 1.00 50.70 C

ATOM 235 O4' DG C 7 34.534 61.717 -34.355 1.00 49.07 O

ATOM 236 C3' DG C 7 35.666 59.854 -35.291 1.00 53.77 C

ATOM 237 O3' DG C 7 37.034 60.280 -35.526 1.00 50.25 O

ATOM 238 C2' DG C 7 35.403 59.617 -33.808 1.00 54.16 C

ATOM 239 C1' DG C 7 35.221 61.043 -33.315 1.00 52.84 C

ATOM 240 N9 DG C 7 34.427 61.208 -32.107 1.00 49.18 N

ATOM 241 C8 DG C 7 33.357 60.460 -31.688 1.00 49.23 C

ATOM 242 N7 DG C 7 32.859 60.885 -30.559 1.00 49.36 N

ATOM 243 C5 DG C 7 33.658 61.972 -30.223 1.00 45.61 C

ATOM 244 C6 DG C 7 33.595 62.855 -29.120 1.00 43.93 C

ATOM 245 O6 DG C 7 32.817 62.849 -28.181 1.00 48.29 O

ATOM 246 N1 DG C 7 34.572 63.828 -29.184 1.00 48.24 N

ATOM 247 C2 DG C 7 35.501 63.943 -30.187 1.00 51.08 C

ATOM 248 N2 DG C 7 36.385 64.954 -30.084 1.00 48.89 N

ATOM 249 N3 DG C 7 35.566 63.129 -31.218 1.00 51.58 N

ATOM 250 C4 DG C 7 34.622 62.174 -31.171 1.00 45.71 C

ATOM 251 P DA C 8 38.033 59.370 -36.407 1.00 50.53 P

ATOM 252 OP1 DA C 8 37.594 59.400 -37.818 1.00 54.92 O

ATOM 253 OP2 DA C 8 38.282 58.052 -35.740 1.00 48.74 O

ATOM 254 O5' DA C 8 39.371 60.212 -36.338 1.00 53.18 O

ATOM 255 C5' DA C 8 39.365 61.593 -36.705 1.00 48.77 C

ATOM 256 C4' DA C 8 40.338 62.376 -35.849 1.00 50.89 C

ATOM 257 O4' DA C 8 39.680 62.759 -34.612 1.00 54.00 O

ATOM 258 C3' DA C 8 41.610 61.600 -35.469 1.00 49.06 C

ATOM 259 O3' DA C 8 42.807 62.293 -35.881 1.00 50.06 O

ATOM 260 C2' DA C 8 41.509 61.350 -33.967 1.00 49.82 C

ATOM 261 C1' DA C 8 40.409 62.289 -33.477 1.00 49.02 C

ATOM 262 N9 DA C 8 39.451 61.633 -32.614 1.00 42.96 N

ATOM 263 C8 DA C 8 38.713 60.510 -32.851 1.00 44.89 C

ATOM 264 N7 DA C 8 37.921 60.181 -31.860 1.00 46.16 N

ATOM 265 C5 DA C 8 38.160 61.165 -30.899 1.00 47.10 C

ATOM 266 C6 DA C 8 37.648 61.391 -29.589 1.00 41.87 C

ATOM 267 N6 DA C 8 36.742 60.623 -28.960 1.00 44.15 N

ATOM 268 N1 DA C 8 38.122 62.460 -28.929 1.00 47.70 N

ATOM 269 C2 DA C 8 39.055 63.243 -29.525 1.00 49.80 C

ATOM 270 N3 DA C 8 39.609 63.127 -30.722 1.00 43.83 N

ATOM 271 C4 DA C 8 39.109 62.061 -31.364 1.00 44.77 C

ATOM 272 P DC C 9 43.209 63.711 -35.215 1.00 55.00 P

ATOM 273 OP1 DC C 9 42.187 64.272 -34.220 1.00 45.38 O

ATOM 274 OP2 DC C 9 43.640 64.570 -36.356 1.00 55.00 O

ATOM 275 O5' DC C 9 44.591 63.333 -34.488 1.00 55.00 O

ATOM 276 C5' DC C 9 44.629 62.522 -33.292 1.00 55.00 C

ATOM 277 C4' DC C 9 44.806 63.399 -32.071 1.00 55.00 C

ATOM 278 O4' DC C 9 43.485 63.682 -31.530 1.00 55.00 O

ATOM 279 C3' DC C 9 45.575 62.759 -30.908 1.00 55.00 C

ATOM 280 O3' DC C 9 47.034 62.836 -30.939 1.00 51.34 O

ATOM 281 C2' DC C 9 45.014 63.518 -29.719 1.00 53.94 C

ATOM 282 C1' DC C 9 43.543 63.632 -30.101 1.00 55.00 C

ATOM 283 N1 DC C 9 42.749 62.473 -29.677 1.00 53.80 N

ATOM 284 C2 DC C 9 41.948 62.577 -28.531 1.00 55.00 C

ATOM 285 O2 DC C 9 41.933 63.659 -27.875 1.00 51.65 O

ATOM 286 N3 DC C 9 41.209 61.505 -28.160 1.00 55.00 N

ATOM 287 C4 DC C 9 41.251 60.373 -28.874 1.00 51.33 C

ATOM 288 N4 DC C 9 40.490 59.342 -28.467 1.00 50.82 N

ATOM 289 C5 DC C 9 42.063 60.246 -30.030 1.00 47.38 C

ATOM 290 C6 DC C 9 42.788 61.309 -30.393 1.00 50.58 C

TER 291 DC C 9

ATOM 292 O5' DA D 10 47.624 63.612 -28.260 1.00 40.15 O

ATOM 293 C5' DA D 10 47.713 64.975 -27.773 1.00 41.23 C

ATOM 294 C4' DA D 10 46.511 65.414 -26.963 1.00 41.91 C

ATOM 295 O4' DA D 10 45.415 64.503 -27.278 1.00 34.07 O

ATOM 296 C3' DA D 10 46.730 65.371 -25.439 1.00 41.10 C

ATOM 297 O3' DA D 10 46.210 66.592 -24.792 1.00 47.10 O

ATOM 298 C2' DA D 10 45.982 64.101 -25.023 1.00 41.97 C

ATOM 299 C1' DA D 10 44.923 63.855 -26.101 1.00 38.41 C

ATOM 300 N9 DA D 10 44.675 62.435 -26.414 1.00 38.72 N

ATOM 301 C8 DA D 10 45.173 61.679 -27.472 1.00 40.02 C

ATOM 302 N7 DA D 10 44.754 60.422 -27.482 1.00 39.04 N

ATOM 303 C5 DA D 10 43.933 60.329 -26.356 1.00 40.81 C

ATOM 304 C6 DA D 10 43.157 59.246 -25.793 1.00 40.05 C

ATOM 305 N6 DA D 10 43.119 58.008 -26.271 1.00 40.66 N

ATOM 306 N1 DA D 10 42.421 59.506 -24.697 1.00 40.43 N

ATOM 307 C2 DA D 10 42.460 60.760 -24.175 1.00 41.52 C

ATOM 308 N3 DA D 10 43.150 61.851 -24.587 1.00 42.57 N

ATOM 309 C4 DA D 10 43.872 61.570 -25.689 1.00 42.70 C

ATOM 310 P DT D 11 46.893 67.211 -23.404 1.00 55.00 P

ATOM 311 OP1 DT D 11 46.017 68.337 -22.865 1.00 42.80 O

ATOM 312 OP2 DT D 11 48.380 67.461 -23.583 1.00 51.84 O

ATOM 313 O5' DT D 11 46.747 66.066 -22.299 1.00 53.94 O

ATOM 314 C5' DT D 11 45.460 65.552 -21.952 1.00 52.33 C

ATOM 315 C4' DT D 11 45.559 64.731 -20.697 1.00 44.09 C

ATOM 316 O4' DT D 11 45.421 63.329 -20.962 1.00 45.97 O

ATOM 317 C3' DT D 11 46.866 64.880 -19.959 1.00 46.39 C

ATOM 318 O3' DT D 11 46.407 64.961 -18.616 1.00 41.22 O

ATOM 319 C2' DT D 11 47.680 63.644 -20.388 1.00 40.78 C

ATOM 320 C1' DT D 11 46.633 62.582 -20.733 1.00 43.45 C

ATOM 321 N1 DT D 11 46.771 61.687 -21.943 1.00 38.73 N

ATOM 322 C2 DT D 11 45.775 60.732 -22.043 1.00 40.38 C

ATOM 323 O2 DT D 11 44.912 60.601 -21.210 1.00 45.18 O

ATOM 324 N3 DT D 11 45.812 59.921 -23.163 1.00 44.88 N

ATOM 325 C4 DT D 11 46.732 59.959 -24.189 1.00 48.90 C

ATOM 326 O4 DT D 11 46.609 59.153 -25.135 1.00 51.75 O

ATOM 327 C5 DT D 11 47.782 60.975 -24.031 1.00 50.82 C

ATOM 328 C7 DT D 11 48.832 61.097 -25.085 1.00 46.89 C

ATOM 329 C6 DT D 11 47.752 61.775 -22.920 1.00 48.86 C

ATOM 330 P DA D 12 47.427 65.166 -17.409 1.00 44.05 P

ATOM 331 OP1 DA D 12 46.773 66.296 -16.675 1.00 51.19 O

ATOM 332 OP2 DA D 12 48.846 65.290 -17.819 1.00 39.32 O

ATOM 333 O5' DA D 12 47.222 63.798 -16.631 1.00 41.66 O

ATOM 334 C5' DA D 12 45.897 63.395 -16.308 1.00 42.93 C

ATOM 335 C4' DA D 12 45.846 61.943 -15.907 1.00 40.30 C

ATOM 336 O4' DA D 12 46.015 61.104 -17.065 1.00 38.86 O

ATOM 337 C3' DA D 12 46.886 61.483 -14.878 1.00 36.09 C

ATOM 338 O3' DA D 12 46.159 60.565 -14.029 1.00 39.85 O

ATOM 339 C2' DA D 12 47.912 60.794 -15.755 1.00 29.38 C

ATOM 340 C1' DA D 12 46.982 60.146 -16.754 1.00 33.47 C

ATOM 341 N9 DA D 12 47.602 59.720 -17.989 1.00 37.85 N

ATOM 342 C8 DA D 12 48.522 60.341 -18.785 1.00 43.89 C

ATOM 343 N7 DA D 12 48.875 59.629 -19.823 1.00 41.94 N

ATOM 344 C5 DA D 12 48.122 58.462 -19.688 1.00 44.73 C

ATOM 345 C6 DA D 12 48.045 57.276 -20.442 1.00 50.44 C

ATOM 346 N6 DA D 12 48.771 57.045 -21.548 1.00 55.00 N

ATOM 347 N1 DA D 12 47.195 56.316 -20.021 1.00 43.24 N

ATOM 348 C2 DA D 12 46.503 56.525 -18.937 1.00 46.08 C

ATOM 349 N3 DA D 12 46.498 57.577 -18.141 1.00 48.18 N

ATOM 350 C4 DA D 12 47.339 58.519 -18.579 1.00 37.62 C

ATOM 351 P DT D 13 46.630 60.215 -12.517 1.00 37.63 P

ATOM 352 OP1 DT D 13 45.320 60.118 -11.796 1.00 40.97 O

ATOM 353 OP2 DT D 13 47.701 61.144 -11.966 1.00 22.15 O

ATOM 354 O5' DT D 13 47.057 58.681 -12.665 1.00 29.87 O

ATOM 355 C5' DT D 13 46.044 57.752 -13.089 1.00 23.04 C

ATOM 356 C4' DT D 13 46.589 56.352 -13.196 1.00 33.54 C

ATOM 357 O4' DT D 13 46.901 56.124 -14.582 1.00 27.11 O

ATOM 358 C3' DT D 13 47.851 56.097 -12.374 1.00 31.73 C

ATOM 359 O3' DT D 13 47.609 55.118 -11.307 1.00 32.77 O

ATOM 360 C2' DT D 13 48.917 55.748 -13.394 1.00 26.91 C

ATOM 361 C1' DT D 13 48.162 55.533 -14.709 1.00 37.09 C

ATOM 362 N1 DT D 13 48.866 56.080 -15.935 1.00 37.48 N

ATOM 363 C2 DT D 13 48.681 55.389 -17.089 1.00 36.31 C

ATOM 364 O2 DT D 13 47.917 54.437 -17.143 1.00 29.73 O

ATOM 365 N3 DT D 13 49.412 55.865 -18.187 1.00 39.84 N

ATOM 366 C4 DT D 13 50.278 56.982 -18.213 1.00 33.61 C

ATOM 367 O4 DT D 13 50.897 57.290 -19.284 1.00 29.75 O

ATOM 368 C5 DT D 13 50.371 57.686 -16.944 1.00 32.94 C

ATOM 369 C7 DT D 13 51.219 58.911 -16.841 1.00 30.73 C

ATOM 370 C6 DT D 13 49.678 57.204 -15.897 1.00 32.29 C

ATOM 371 P DG D 14 48.141 53.580 -11.406 1.00 34.52 P

ATOM 372 OP1 DG D 14 47.664 52.986 -10.144 1.00 43.03 O

ATOM 373 OP2 DG D 14 49.567 53.367 -11.832 1.00 34.75 O

ATOM 374 O5' DG D 14 47.186 52.961 -12.492 1.00 34.22 O

ATOM 375 C5' DG D 14 46.685 51.656 -12.361 1.00 20.60 C

ATOM 376 C4' DG D 14 47.259 50.790 -13.454 1.00 33.01 C

ATOM 377 O4' DG D 14 47.979 51.564 -14.462 1.00 35.41 O

ATOM 378 C3' DG D 14 48.234 49.764 -12.908 1.00 29.23 C

ATOM 379 O3' DG D 14 47.763 48.513 -13.393 1.00 35.76 O

ATOM 380 C2' DG D 14 49.564 50.178 -13.524 1.00 25.97 C

ATOM 381 C1' DG D 14 49.192 50.926 -14.789 1.00 28.17 C

ATOM 382 N9 DG D 14 50.184 51.952 -15.100 1.00 34.28 N

ATOM 383 C8 DG D 14 50.616 52.906 -14.226 1.00 34.34 C

ATOM 384 N7 DG D 14 51.520 53.693 -14.740 1.00 39.87 N

ATOM 385 C5 DG D 14 51.701 53.232 -16.042 1.00 35.52 C

ATOM 386 C6 DG D 14 52.591 53.677 -17.075 1.00 39.91 C

ATOM 387 O6 DG D 14 53.418 54.608 -17.053 1.00 55.00 O

ATOM 388 N1 DG D 14 52.481 52.928 -18.241 1.00 39.09 N

ATOM 389 C2 DG D 14 51.646 51.909 -18.417 1.00 44.38 C

ATOM 390 N2 DG D 14 51.727 51.366 -19.660 1.00 29.85 N

ATOM 391 N3 DG D 14 50.800 51.453 -17.458 1.00 45.72 N

ATOM 392 C4 DG D 14 50.888 52.170 -16.300 1.00 35.90 C

ATOM 393 P DT D 15 48.194 47.114 -12.700 1.00 35.88 P

ATOM 394 OP1 DT D 15 46.932 46.335 -12.890 1.00 37.64 O

ATOM 395 OP2 DT D 15 48.824 47.131 -11.354 1.00 25.79 O

ATOM 396 O5' DT D 15 49.325 46.567 -13.699 1.00 32.23 O

ATOM 397 C5' DT D 15 49.189 46.644 -15.134 1.00 31.46 C

ATOM 398 C4' DT D 15 50.328 45.904 -15.799 1.00 34.61 C

ATOM 399 O4' DT D 15 51.295 46.824 -16.398 1.00 25.68 O

ATOM 400 C3' DT D 15 51.103 45.072 -14.788 1.00 31.64 C

ATOM 401 O3' DT D 15 51.522 43.854 -15.422 1.00 40.68 O

ATOM 402 C2' DT D 15 52.257 45.992 -14.432 1.00 32.75 C

ATOM 403 C1' DT D 15 52.526 46.775 -15.722 1.00 28.85 C

ATOM 404 N1 DT D 15 53.037 48.171 -15.524 1.00 30.96 N

ATOM 405 C2 DT D 15 53.943 48.681 -16.421 1.00 32.87 C

ATOM 406 O2 DT D 15 54.319 48.061 -17.399 1.00 35.12 O

ATOM 407 N3 DT D 15 54.391 49.968 -16.132 1.00 30.06 N

ATOM 408 C4 DT D 15 54.000 50.779 -15.053 1.00 34.39 C

ATOM 409 O4 DT D 15 54.480 51.930 -14.885 1.00 32.34 O

ATOM 410 C5 DT D 15 53.046 50.202 -14.198 1.00 29.25 C

ATOM 411 C7 DT D 15 52.557 51.028 -13.072 1.00 23.55 C

ATOM 412 C6 DT D 15 52.619 48.941 -14.450 1.00 36.88 C

ATOM 413 P DC D 16 51.886 42.548 -14.537 1.00 47.56 P

ATOM 414 OP1 DC D 16 50.930 41.546 -15.049 1.00 52.01 O

ATOM 415 OP2 DC D 16 51.911 42.850 -13.066 1.00 39.57 O

ATOM 416 O5' DC D 16 53.354 42.173 -15.069 1.00 43.85 O

ATOM 417 C5' DC D 16 53.968 43.038 -16.048 1.00 45.50 C

ATOM 418 C4' DC D 16 55.329 42.566 -16.521 1.00 41.40 C

ATOM 419 O4' DC D 16 55.842 43.779 -17.142 1.00 40.11 O

ATOM 420 C3' DC D 16 56.379 42.159 -15.469 1.00 42.83 C

ATOM 421 O3' DC D 16 56.617 40.705 -15.443 1.00 50.50 O

ATOM 422 C2' DC D 16 57.626 42.945 -15.872 1.00 43.83 C

ATOM 423 C1' DC D 16 57.063 44.199 -16.542 1.00 43.62 C

ATOM 424 N1 DC D 16 56.781 45.377 -15.651 1.00 48.11 N

ATOM 425 C2 DC D 16 56.961 46.695 -16.157 1.00 49.75 C

ATOM 426 O2 DC D 16 57.343 46.843 -17.334 1.00 52.85 O

ATOM 427 N3 DC D 16 56.705 47.765 -15.344 1.00 47.43 N

ATOM 428 C4 DC D 16 56.288 47.569 -14.094 1.00 47.79 C

ATOM 429 N4 DC D 16 56.049 48.633 -13.353 1.00 48.62 N

ATOM 430 C5 DC D 16 56.097 46.262 -13.551 1.00 48.58 C

ATOM 431 C6 DC D 16 56.351 45.207 -14.352 1.00 47.19 C

ATOM 432 P DA D 17 57.265 39.990 -14.116 1.00 50.88 P

ATOM 433 OP1 DA D 17 57.140 38.503 -14.120 1.00 52.42 O

ATOM 434 OP2 DA D 17 56.800 40.755 -12.911 1.00 53.33 O

ATOM 435 O5' DA D 17 58.823 40.250 -14.254 1.00 47.97 O

ATOM 436 C5' DA D 17 59.486 40.108 -15.506 1.00 50.60 C

ATOM 437 C4' DA D 17 60.971 40.244 -15.279 1.00 54.94 C

ATOM 438 O4' DA D 17 61.309 41.644 -15.121 1.00 53.71 O

ATOM 439 C3' DA D 17 61.360 39.544 -13.981 1.00 51.07 C

ATOM 440 O3' DA D 17 62.073 38.361 -14.358 1.00 55.00 O

ATOM 441 C2' DA D 17 62.175 40.569 -13.204 1.00 47.55 C

ATOM 442 C1' DA D 17 61.807 41.915 -13.816 1.00 50.35 C

ATOM 443 N9 DA D 17 60.813 42.765 -13.133 1.00 53.31 N

ATOM 444 C8 DA D 17 59.602 42.451 -12.564 1.00 51.71 C

ATOM 445 N7 DA D 17 58.974 43.490 -12.051 1.00 48.20 N

ATOM 446 C5 DA D 17 59.828 44.558 -12.296 1.00 49.79 C

ATOM 447 C6 DA D 17 59.745 45.973 -12.026 1.00 48.14 C

ATOM 448 N6 DA D 17 58.717 46.617 -11.406 1.00 53.16 N

ATOM 449 N1 DA D 17 60.784 46.730 -12.432 1.00 50.75 N

ATOM 450 C2 DA D 17 61.818 46.140 -13.058 1.00 55.00 C

ATOM 451 N3 DA D 17 62.003 44.864 -13.366 1.00 55.00 N

ATOM 452 C4 DA D 17 60.967 44.120 -12.956 1.00 53.56 C

ATOM 453 P DC D 18 62.881 37.531 -13.257 1.00 55.00 P

ATOM 454 OP1 DC D 18 63.806 36.569 -13.918 1.00 55.00 O

ATOM 455 OP2 DC D 18 61.792 37.023 -12.363 1.00 55.00 O

ATOM 456 O5' DC D 18 63.725 38.668 -12.481 1.00 55.00 O

ATOM 457 C5' DC D 18 64.720 39.484 -13.160 1.00 55.00 C

ATOM 458 C4' DC D 18 65.301 40.571 -12.257 1.00 55.00 C

ATOM 459 O4' DC D 18 64.345 41.579 -11.831 1.00 55.00 O

ATOM 460 C3' DC D 18 66.076 40.169 -10.994 1.00 55.00 C

ATOM 461 O3' DC D 18 67.376 40.771 -11.129 1.00 55.00 O