FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Pak, Mtl
FlyBase ID
FBig0000101250
Interaction Network
Interactions Browser links
Pak network
Mtl network
Reported Interactions
FBrf0167957-10.PD.WB
Reference
Fan et al., 2003
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Pak 

Pak

bait

GST tag

Pak 
Mtl 

Mtl

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Pak 
Rac-interacting domain
sufficient binding region
aa 77-151
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Cells were treated with the robo ligand sli for 10 minutes before the pull down assay.

(Fan et al., 2003)

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from transfected HEK293T cell extract.

(Fan et al., 2003)

The Pak-Mtl interaction is increased when cells express a functional robo receptor and are treated with the robo ligand sli.

(Fan et al., 2003)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)