required for the specialization of mechanosensory cilium of chordotonal neurons
Please see the JBrowse view of Dmel\fd3F for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.47
Stop-codon suppression (UGA) postulated; FBrf0234051.
Gene model reviewed during 6.25
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\fd3F using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
fd3F transcript is expressed in the embryonic chordotonal organ precursors, including the precursors to lch5, lch1, vch1, vch2, dch3.
fd3F transcript is maternally expressed. Maternal and/or zygotic transcripts are uniformly distributed until mid-embryonic stage 12. During mid-stage 12, uniform levels of transcript distribution decrease and a spatially restricted pattern of expression appears in one lateral and one ventral cluster of cells within each trunk hemisegment as well as in clusters within the embryonic head. By embryonic stage 13, expression is restricted exclusively in these cell clusters, which have a distribution suggesting that they are chordotonal organ precursor cells.
fd3F protein is expressed in the embryonic chordotonal organ precursors, including the precursors to lch5, lch1, vch1, vch2, dch3.
JBrowse - Visual display of RNA-Seq signals
View Dmel\fd3F in JBrowse1-5
1-4.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
"fd3F" is not a pseudogene; its indels maintain a reading frame.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of fd3F results in reduced arborization of ddaD and ddaE neurons and defects in dendrite morphogenesis.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Source for merge of: fd3F CG12632
Source for merge of: CG15238 CG18771
Source for merge of: fd3F CG32779
Annotations CG12632 and CG32779 merged as CG44123 in release 5.47 of the genome annotation. In addition to data described in FBrf0218629, merge supported by second tier modENCODE RNA-seq junction data (FBrf0217580).
Annotations CG15238 and CG18771 merged as CG32779 in release 3 of the genome annotation.
"l(1)G0433" may affect "fd3F".
Source for merge of fd3F CG12632 was sequence comparison ( date:021112 ).