FlyBase Gene Report: Dmel\cuff

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Gene: Dmel\cuff

General Information

Symbol

Dmel\cuff

Species

D. melanogaster

Name

cutoff

Annotation Symbol

CG13190

Feature Type

protein_coding_gene

FlyBase ID

FBgn0260932

Gene Model Status

Stock Availability

9 publicly available

Gene Summary

cutoff (cuff) encodes a protein that interacts with the products of rhi and del in a germline complex that allows noncanonical transcription of dual-strand piRNA clusters. The product of cuff is therefore an integral part of the piRNA response to transposon activity in the germline. In its absence, a DNA damage checkpoint is activated leading to ventralization of the egg and embryo. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)

All Summaries

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:11,886,067..11,887,603 [+]

Recombination map

2-65

RefSeq locus

NT_033778 REGION:11886067..11887603

Sequence

Get Decorated FASTA

Genomic Maps

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (18 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables piRNA cluster binding

inferred from direct assay

(Pritykin et al., 2017)

NOT enables mRNA 5'-diphosphatase activity

inferred from direct assay

(Chen et al., 2016)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (12 terms)

Terms Based on Experimental Evidence (10 terms)

CV Term

Evidence

References

involved_in dorsal/ventral pattern formation

inferred from mutant phenotype

(Chen et al., 2007)

involved_in germarium-derived female germ-line cyst formation

inferred from mutant phenotype

(Chen et al., 2007)

involved_in oocyte karyosome formation

inferred from mutant phenotype

(Chen et al., 2007)

involved_in oogenesis

inferred from high throughput mutant phenotype

(Schupbach and Wieschaus, 1991)

involved_in ovarian fusome organization

inferred from mutant phenotype

(Chen et al., 2007)

involved_in P granule organization

inferred from mutant phenotype

(Pane et al., 2011)

involved_in positive regulation of piRNA transcription

inferred from mutant phenotype

(Pritykin et al., 2017)

inferred from mutant phenotype

(Pane et al., 2011)

involved_in positive regulation of snRNA transcription by RNA polymerase II

inferred from mutant phenotype

(Pritykin et al., 2017)

involved_in siRNA processing

inferred from mutant phenotype

(Chen et al., 2007)

involved_in snoRNA transcription by RNA polymerase II

inferred from mutant phenotype

(Pritykin et al., 2017)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in NAD-cap decapping

inferred from biological aspect of ancestor with PANTHER:PTN000273640

(GO Reference Genome Project, 2011-)

involved_in nuclear-transcribed mRNA catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000273640

(GO Reference Genome Project, 2011-)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Chen et al., 2007)

located_in nucleus

inferred from direct assay

(Pane et al., 2011)

located_in perinuclear region of cytoplasm

inferred from direct assay

(Chen et al., 2007)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in cytosol

inferred from biological aspect of ancestor with PANTHER:PTN000273640

(GO Reference Genome Project, 2011-)

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000273640

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

RHINO-DEADLOCK-CUTOFF COMPLEX

UNCLASSIFIED PSEUDOENZYMES

Protein Family (UniProt)

Belongs to the DXO/Dom3Z family. (Q9V629)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

cutoff (cuff) encodes a protein that interacts with the products of rhi and del in a germline complex that allows noncanonical transcription of dual-strand piRNA clusters. The product of cuff is therefore an integral part of the piRNA response to transposon activity in the germline. In its absence, a DNA damage checkpoint is activated leading to ventralization of the egg and embryo. [Date last reviewed: 2019-03-07]

Gene Group (FlyBase)

RHINO-DEADLOCK-CUTOFF COMPLEX -: The Rhino-Deadlock-Cutoff (RDC) complex is a trimer that binds H3K9me3 and anchors itself onto dual-strand clusters. RDC complex regulates the non-canonical transcription and co-transcriptional processing of PIWI interacting RNA (piRNA) precursors and transposon silencing. (Adapted from FBrf0225218 and FBrf0250952).
UNCLASSIFIED PSEUDOENZYMES -: This group comprises pseudoenzymes that do not classify under other groups in FlyBase.

Protein Function (UniProtKB)

Involved in the piRNA pathway in germline tissues (PubMed:17363252, PubMed:21952049). Part of the Rhino-Deadlock-Cutoff (RDC) complex that stimulates piRNA biogenesis from chromatin regions corresponding to dual-strand, but not single-stranded, piRNA clusters (PubMed:24906153, PubMed:25085419, PubMed:27292797). Promotes transcription of long piRNA precursors by preventing termination at canonical poly(A) sites (PubMed:27292797). As part of the RDC complex, is recruited to chromatin enriched in histone modification H3K9me3 and might contribute to complex interaction by binding nascent transcript nucleic acid chains (PubMed:24906153, PubMed:25085419, PubMed:27292797). Associates with chromatin upon exposure to homologous piRNA (PubMed:27292797). Suppresses cleavage at canonical poly(A) sites by blocking recruitment of the cleavage and polyadenylation specificity factor (CPSF) complex and prevents transcriptional termination by RNA polymerase II, facilitating transcriptional read-through (PubMed:27292797). As part of the RDC complex, involved in suppression of splicing (PubMed:27292797). Catalytically inactive, lacking 5'-3' exonuclease and pyrophosphohydrolase activities (PubMed:27292797). Stabilizes uncapped piRNA precursors in the nucleus, probably by sequestering or blocking the exonuclease activity of Rat1 (PubMed:27292797). May also be involved in siRNA biogenesis from dual-strand piRNA clusters (PubMed:25085419).

(UniProt, Q9V629)

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

cuff: cutoff (T. Schupbach)

female-sterile; homozygous females often have underdeveloped ovaries which seem to lack germ cells altogether. In some females, a small number of developing egg chambers is found; these never develop beyond the first few stages of oogenesis.

Summary (Interactive Fly)

a protein related to a yeast transcription termination factor - involved in piwiRNA cluster expression, which is critical for oocyte development

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\cuff for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9V629)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.42

Gene model reviewed during 5.49

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0088034

1295

384

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

FBpp0087141

44.8

384

7.47

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Component of the Rhino-Deadlock-Cutoff (RDC) complex, composed of rhi/rhino, del/deadlock and cuff/cutoff (PubMed:24906153). Interacts with rhi/rhino; this interaction is indirect and is mediated by del/deadlock (PubMed:21952049, PubMed:24906153, PubMed:25085419). Interacts with del/deadlock (via C-terminal); this interaction is direct (PubMed:24906153). Interacts with Rat1 (PubMed:27292797).

(UniProt, Q9V629)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Q9V629

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\cuff using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

cuff_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.91

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Chen et al., 2007)

located_in nucleus

inferred from direct assay

(Pane et al., 2011)

located_in perinuclear region of cytoplasm

inferred from direct assay

(Chen et al., 2007)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\cuff in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\cuff

View exonic expression by tissue for Dmel\cuff

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0260932

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

36269/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0260932

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0033662

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0260932

Flygut - An atlas of the Drosophila adult midgut

FBgn0260932

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 10 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 16 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of cuff

Transgenic constructs containing regulatory region of cuff

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

cuff^GD7957

viable, with Scer\GAL4^Mef2.PR

cuff^GD7957

viable, with Scer\GAL4^pnr-MD237

cuff^GD7957

Sterility

Allele

female sterile, with Scer\GAL4^nanos.PG

cuff^KK103622

Phenotype manifest in

Allele

egg chorion (with cuff^KG05951)

cuff^WM25

egg chorion (with cuff^QQ37)

cuff^WM25

egg chorion (with cuff^WM25)

female fusome (with cuff^KG05951)

cuff^WM25

female fusome (with cuff^WM25)

cuff^KG05951

female germline cyst (with cuff^KG05951)

cuff^WM25

female germline cyst (with cuff^WM25)

cuff^KG05951

germarium (with cuff^KG05951)

cuff^WM25

germarium (with cuff^WM25)

cuff^KG05951

oocyte nucleus (with cuff^KG05951)

cuff^WM25

oocyte nucleus (with cuff^WM25)

cuff^KG05951

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (1)

4 of 14

Yes

No

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (1)

4 of 14

Yes

No

Mus musculus (laboratory mouse) (1)

3 of 14

Yes

No

Xenopus tropicalis (Western clawed frog) (1)

3 of 13

Yes

No

Danio rerio (Zebrafish) (1)

2 of 14

Yes

No

Caenorhabditis elegans (Nematode, roundworm) (11)

4 of 14

Yes

No

3 of 14

No

No

3 of 14

No

No

3 of 14

No

Yes

2 of 14

No

Yes

2 of 14

No

Yes

2 of 14

No

Yes

2 of 14

No

Yes

2 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

No

Anopheles gambiae (African malaria mosquito) (1)

Agam\AgaP_AGAP007205

5 of 12

Yes

No

Arabidopsis thaliana (thale-cress) (1)

4 of 13

Yes

No

Saccharomyces cerevisiae (Brewer's yeast) (2)

4 of 13

Yes

No

2 of 13

No

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

3 of 12

Yes

No

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:cuff. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (1)

5 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

DXO; decapping exoribonuclease

4 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

anti tag coimmunoprecipitation, anti tag western blot

(Chen et al., 2016)

(ElMaghraby et al., 2019, Mohn et al., 2014)

anti tag coimmunoprecipitation, anti tag western blot, western blot

(Le Thomas et al., 2014, Pane et al., 2011)

anti tag coimmunoprecipitation, anti tag western blot

(Hur et al., 2016)

anti tag coimmunoprecipitation, anti tag western blot

(Kordyukova et al., 2020)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Chen et al., 2007)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Gell and Reenan, 2013)

External Data

Subunit Structure (UniProtKB)

Component of the Rhino-Deadlock-Cutoff (RDC) complex, composed of rhi/rhino, del/deadlock and cuff/cutoff (PubMed:24906153). Interacts with rhi/rhino; this interaction is indirect and is mediated by del/deadlock (PubMed:21952049, PubMed:24906153, PubMed:25085419). Interacts with del/deadlock (via C-terminal); this interaction is direct (PubMed:24906153). Interacts with Rat1 (PubMed:27292797).

(UniProt, Q9V629 )

Linkouts

BioGRID - A database of protein and genetic interactions.

62054

DroID - A comprehensive database of gene and protein interactions.

FBgn0260932

MIST (protein-protein) - An integrated Molecular Interaction Database

36269

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2R

Recombination map

2-65

Cytogenetic map

Sequence location

2R:11,886,067..11,887,603 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

48C5-48C5

Limits computationally determined from genome sequence between P{EP}wal^EP825&P{PZ}wal⁰²⁵¹⁶ and P{PZ}Ef1α48D⁰¹²⁷⁵

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-65

(FlyBase, 2016)

2-66.0

(Comeron et al., 2012)

2-61

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

43932

y¹ w^*; Mi{MIC}cuff^MI07837

14462

y¹ w^67c23; P{SUPor-P}cuff^KG05951

35182

y¹ sc^* v¹ sev²¹; P{TRiP.GL00054}attP2

35318

y¹ sc^* v¹ sev²¹; P{TRiP.GL00224}attP2

13190R-4

GL00054

y¹ sc^* v¹ sev²¹; P{TRiP.GL00054}attP2

GL00224

y¹ sc^* v¹ sev²¹; P{TRiP.GL00224}attP2

v100835

P{KK103622}VIE-260B

v43001

w¹¹¹⁸; P{GD7957}v43001

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (4)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP10749

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0260932

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0260932

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Mohn et al., 2014)

monoclonal

(Kibanov et al., 2011)

Commercially Available Antibodies

Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research

Cutoff_9D5-8C9

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

The cuff locus affects early oogenesis: mutations cause the production of few, defective germ cells.

(Schupbach and Wieschaus, 1991)

Relationship to Other Genes

Source for database merge of

Source for merge of: cuff CG13190

(Chen et al., 2007)

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG13190

(Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2011.7.19, Kadam et al., 2009, Keleman et al., 2009.8.5, Chen et al., 2007)

CUFF

(Gamez et al., 2020)

Cuff

(Suyama and Kai, 2025, Ho et al., 2024, Huang and Wong, 2021, Wang et al., 2021, Cacchione et al., 2020, Kordyukova et al., 2020, Sato and Siomi, 2020, Rogers et al., 2017, Ryazansky et al., 2017, Yang and Xi, 2017, Chen et al., 2016, Hirakata and Siomi, 2016, Guzzardo et al., 2013)

mel-cuff

(Parhad et al., 2020)

Name Synonyms

CG13190

Cuff

(Patel et al., 2024)

Cutoff

(Kotov et al., 2022, Wang et al., 2021, ElMaghraby et al., 2019, Hirakata and Siomi, 2019, Yamashiro and Siomi, 2018, Huang et al., 2017, Ryazansky et al., 2017, Chen et al., 2016, Hirakata and Siomi, 2016, Chen and Aravin, 2015, Le Thomas et al., 2014, Mani and Juliano, 2013)

cutoff

(Schüpbach, 2019, Marie et al., 2017, Pritykin et al., 2017, Specchia et al., 2017, Blumenstiel et al., 2016, Wylie et al., 2016, Han et al., 2015, Gell and Reenan, 2013, Handler et al., 2013, Castillo et al., 2011, Olivieri et al., 2010, Chen et al., 2007)

Secondary FlyBase IDs

FBgn0000390
FBgn0033662

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 29 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

36269

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAF58610

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9V629

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9V629

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9V629

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0260932

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

36269/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0260932

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0260932

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG13190

MARRVEL_MODEL - MARRVEL (model organism gene)

36269

Linkouts

BioGRID - A database of protein and genetic interactions.

62054

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0260932

DroID - A comprehensive database of gene and protein interactions.

FBgn0260932

DRSC - Results frm RNAi screens

FBgn0260932

Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research

Cutoff_9D5-8C9

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

cuff_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0033662

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0260932

Flygut - An atlas of the Drosophila adult midgut

FBgn0260932

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

36269

References (87)