FlyBase Gene Report: Dmel\trv

General Information

Symbol

Dmel\trv

Species

D. melanogaster

Name

trivet

Annotation Symbol

CG34362

Feature Type

protein_coding_gene

FlyBase ID

FBgn0085391

Gene Model Status

Current

Stock Availability

43 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Also Known As

Tia1-like

Key Links

Genomic Location

Cytogenetic map

98B7-98C1

Sequence location

3R:28,026,615..28,090,740 [+]

Recombination map

3-94

RefSeq locus

NT_033777 REGION:28026615..28090740

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (4 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables nucleic acid binding

inferred from electronic annotation with InterPro:IPR035979

(InterPro Project Members, 2004-)

enables protein-RNA adaptor activity

inferred from biological aspect of ancestor with PANTHER:PTN002364906

(GO Reference Genome Project, 2011-)

enables RNA binding

inferred from electronic annotation with InterPro:IPR000504

(InterPro Project Members, 2004-)

Biological Process (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in regulation of alternative mRNA splicing, via spliceosome

inferred from mutant phenotype

(Katzenberger et al., 2009)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in regulation of alternative mRNA splicing, via spliceosome

inferred from biological aspect of ancestor with PANTHER:PTN004150638

(GO Reference Genome Project, 2011-)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\trv for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry E1JIZ9)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.49

Gene model reviewed during 5.47

Gene model reviewed during 5.53

A non-AUG start codon may be used for translation of one or more transcripts of this gene; based on the presence of conserved protein signatures within the 5' UTR without an in-frame AUG (FBrf0243886).

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

trv-RA

FBtr0112583

NM_143352

2495

505

trv-RE

FBtr0334896

NM_001276103

5991

509

trv-RF

FBtr0334897

NM_001276104

7452

498

trv-RI

FBtr0344217

NM_001170283

2729

651

trv-RJ

FBtr0344218

NM_001300644

2530

508

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

trv-PA

FBpp0111495

54.1

505

8.34

FBpp0306917

54.6

509

7.59

FBpp0306918

53.3

498

8.34

FBpp0310623

69.8

651

7.77

FBpp0310624

54.3

508

7.38

A0A0B4LIU0

NP_001287573

AHN57572

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\trv using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.56

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\trv in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\trv

View exonic expression by tissue for Dmel\trv

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0085391

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

43362/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085391

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085391

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085391

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG34362

Flygut - An atlas of the Drosophila adult midgut

FBgn0085391

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of trv

Transgenic constructs containing regulatory region of trv

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 3 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

trv^f00299

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

trv^GD7852

viable, with Scer\GAL4^Mef2.PR

trv^GD7852

viable, with Scer\GAL4^pnr-MD237

trv^GD7852

Sterility

Allele

fertile

trv^f00299

Other Phenotypes

Allele

abnormal heat stress response | third instar larval stage, with Scer\GAL4^ppk.1.9

trv^KK111389

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^ppk.1.9

trv^KK111389

Phenotype manifest in

Allele

dendrite | third instar larval stage, with Scer\GAL4^ppk.1.9

trv^KK111389

larval dorsal multidendritic neuron ddaC | third instar larval stage, with Scer\GAL4^ppk.1.9

trv^KK111389

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (95)

Hsap\TIA1

7 of 14

Yes

Hsap\TIAL1

7 of 14

Yes

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\RBMXL3

1 of 14

Yes

Hsap\RBMY1B

1 of 14

Hsap\RBMY1D

1 of 14

Hsap\RBMY1E

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

144

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (55)

Rnor\Tia1

7 of 14

Yes

Rnor\Tial1

7 of 14

Yes

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (59)

Mmus\Tial1

7 of 14

Yes

6 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (50)

Xtro\tia1

7 of 13

Yes

4 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Danio rerio (Zebrafish) (74)

Drer\tia1

7 of 14

Yes

Drer\tia1l

7 of 14

Yes

Drer\tial1

7 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (42)

Cele\tiar-1

6 of 14

Yes

Cele\tiar-2

6 of 14

Yes

4 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (49)

Agam\AgaP_AGAP005292

6 of 12

Yes

4 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

Agam\AgaP_AGAP013440

1 of 12

Agam\EIF3G_ANOGA

1 of 12

Arabidopsis thaliana (thale-cress) (148)

Atha\AT3G14100

8 of 13

Yes

Atha\UBP1A

8 of 13

Yes

Atha\UBP1B

8 of 13

Yes

Atha\FPA

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\AT1G76460

1 of 13

Atha\AT1G78260

1 of 13

Atha\AT2G14160

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\AT3G46020

1 of 13

Yes

Atha\AT3G48835

1 of 13

Yes

Atha\AT4G12640

1 of 13

Atha\AT4G13860

1 of 13

Yes

Atha\AT4G14300

1 of 13

Atha\AT4G19610

1 of 13

Atha\AT4G20030

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\AT5G19350

1 of 13

Atha\AT5G19960

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\AT5G55550

1 of 13

Atha\AT5G59860

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\GR-RBP5

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\ML5

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (12)

Scer\PUB1

5 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (18)

Spom\csx1

2 of 12

Yes

Spom\SPBC23E6.01c

2 of 12

Yes

Spom\crp79

1 of 12

Yes

Spom\cwf2

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:trv. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (50)

8 of 13

8 of 13

2 of 13

2 of 13

B52

1 of 13

bol

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

fne

1 of 13

heph

1 of 13

hfp

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

LS2

1 of 13

maca

1 of 13

msi

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

snf

1 of 13

snRNP-U1-70K

1 of 13

Spx

1 of 13

sqd

1 of 13

ssx

1 of 13

Sxl

1 of 13

TBPH

1 of 13

tra2

1 of 13

tsu

1 of 13

U2af50

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

TIA1; TIA1 cytotoxic granule associated RNA binding protein

model of amyotrophic lateral sclerosis type 26

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TIA1; TIA1 cytotoxic granule associated RNA binding protein

7 of 14

603518

amyotrophic lateral sclerosis type 26

TIAL1; TIA1 cytotoxic granule associated RNA binding protein like 1

7 of 14

603413

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

trv

two hybrid

(Hu et al., 2017.6.13)

trv - CG1394

two hybrid

(Hu et al., 2017.6.13)

trv - CG44251

two hybrid

(Hu et al., 2017.6.13)

trv - Cpr64Ad

two hybrid

(Hu et al., 2017.6.13)

trv - CycK

two hybrid

(Hu et al., 2017.6.13)

trv - Nf-YA

two hybrid

(Hu et al., 2017.6.13)

trv - RluA-1

two hybrid

(Hu et al., 2017.6.13)

trv - Rox8

two hybrid

(Hu et al., 2017.6.13)

trv - hale

two hybrid

(Hu et al., 2017.6.13)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

68243

DroID - A comprehensive database of gene and protein interactions.

FBgn0085391

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene_with_edited_transcript

(Rodriguez et al., 2012)

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-94

Cytogenetic map

98B7-98C1

Sequence location

3R:28,026,615..28,090,740 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

98B7-98C1

Limits computationally determined from genome sequence between P{PZ}btz^rL203 and P{PZ}l(3)06487⁰⁶⁴⁸⁷

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-94

(FlyBase, 2016)

3-92.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (43)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Korea

12215

P{VT048637-GAL4}attP2

12216

P{VT048645-GAL4}attP2

12516

P{VT048635-GAL4}attP2

12781

P{VT048640-GAL4}attP2

12997

P{VT048655-GAL4}attP2

13546

P{VT048646-GAL4}attP2

15495

P{VT048641-GAL4}attP2

16582

P{VT048645-lexA::GADfl}attP40

17258

P{VT048643-lexA::GADfl}attP40

12870R-4

v102523

v200158

P{VT048643-GAL4}attP2

More stocks available...

Genomic Clones (41)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (22)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0085391

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0085391

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: CG12870 CG12872

(FlyBase Genome Annotators, 2007)

Source for merge of: CG12870 BcDNA:RE10833

(FlyBase, 1996-)

Additional comments

Annotations CG12870 and CG12872 merged as CG34362 in release 5.2 of the genome annotation.

(FlyBase Genome Annotators, 2007)

Source for merge of CG12870 BcDNA:RE10833 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: trv CG34362

(Honjo et al., 2016)

Nomenclature comments

Etymology

Named "trivet" as tissue-specific RNAi-mediated knock-down causes insensitive thermal nociception.

(Honjo et al., 2016)

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

BcDNA:RE10833

CG12870

(Wang et al., 2013, Stuart et al., 2007)

CG12872

CG34362

(Fochler et al., 2017, Honjo et al., 2016, Vernes, 2014, Japanese National Institute of Genetics, 2012.5.21, Rodriguez et al., 2012, Luo et al., 2011, Katzenberger et al., 2009, Keleman et al., 2009.8.5, Perkins et al., 2009, FlyBase Genome Annotators, 2007)

Tia1-like

(Avet-Rochex et al., 2010, Katzenberger et al., 2009)

trv

(Michki et al., 2021, Pang et al., 2021, FlyBase Genome Annotators, 2019-, Meltzer et al., 2019, Croset et al., 2018, Hu et al., 2017.6.13, Rohde et al., 2017, Honjo et al., 2016)

Name Synonyms

CG12870

CG12872

trivet

(Honjo et al., 2016)

Secondary FlyBase IDs

FBgn0063063
FBgn0039570
FBgn0039569

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 49 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

43362

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

E1JIZ9

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

E1JIZ9

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0085391

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

43362/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0085391

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0085391

FlyMine - An integrated database for Drosophila genomics

FBgn0085391

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG34362

MARRVEL_MODEL - MARRVEL (model organism gene)

43362

Linkouts

BioGRID - A database of protein and genetic interactions.

68243

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0085391

DroID - A comprehensive database of gene and protein interactions.

FBgn0085391

DRSC - Results frm RNAi screens

FBgn0085391

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0085391

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0085391

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG34362

Flygut - An atlas of the Drosophila adult midgut

FBgn0085391

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0085391

References (44)

The following external sites may use different assemblies or annotations than FlyBase.

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