FlyBase Gene Report: Dmel\JhI-21

General Information

Symbol

Dmel\JhI-21

Species

D. melanogaster

Name

Juvenile hormone Inducible-21

Annotation Symbol

CG12317

Feature Type

protein_coding_gene

FlyBase ID

FBgn0028425

Gene Model Status

Current

Stock Availability

18 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Also Known As

Jhl-21

Key Links

Genomic Location

Cytogenetic map

33B11-33C1

Sequence location

2L:12,051,755..12,056,042 [-]

Recombination map

2-46

RefSeq locus

NT_033779 REGION:12051755..12056042

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (10 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables L-amino acid transmembrane transporter activity

inferred from biological aspect of ancestor with PANTHER:PTN000208507

(GO Reference Genome Project, 2011-)

enables transmembrane transporter activity

inferred from electronic annotation with InterPro:IPR002293

(InterPro Project Members, 2004-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in carbohydrate homeostasis

inferred from mutant phenotype

(Ziegler et al., 2018)

involved_in cellular response to L-leucine

inferred from direct assay

(Ziegler et al., 2018)

involved_in L-leucine import across plasma membrane

inferred from mutant phenotype

(Reynolds et al., 2009)

involved_in positive regulation of insulin secretion

inferred from mutant phenotype

(Ziegler et al., 2018)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in amino acid transmembrane transport

inferred from biological aspect of ancestor with PANTHER:PTN000208507

(GO Reference Genome Project, 2011-)

involved_in transmembrane transport

inferred from electronic annotation with InterPro:IPR002293

(InterPro Project Members, 2004-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in membrane

inferred from electronic annotation with InterPro:IPR002293

(InterPro Project Members, 2004-)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN000208507

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

L-TYPE AMINO ACID TRANSPORTERS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

L-TYPE AMINO ACID TRANSPORTERS -: L-type amino acid transporters (LATs) are system L, sodium-independent transporters responsible for transport of bulky neutral amino acids. LATs form the light chains or catalytic chains of the heterodimeric amino acid transporters (HATs). (Adapted from FBrf0207965 and PMID:14770310).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\JhI-21 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VKC2)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.51

Gene model reviewed during 5.56

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

JhI-21-RA

FBtr0089655

NM_135698

2125

500

JhI-21-RB

FBtr0089656

NM_164988

2089

500

JhI-21-RC

FBtr0305089

NM_001259067

2149

500

JhI-21-RD

FBtr0342608

NM_001298934

2119

500

JhI-21-RE

FBtr0346427

NM_001298935

2182

500

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

JhI-21-PA

FBpp0088598

54.8

500

8.68

FBpp0088925

54.8

500

8.68

FBpp0293626

54.8

500

8.68

FBpp0309548

54.8

500

8.68

FBpp0312092

54.8

500

8.68

Q9VKC2

NP_001285864

AHN54378

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

500 aa isoforms: JhI-21-PA, JhI-21-PB, JhI-21-PC, JhI-21-PD, JhI-21-PE

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Q9VKC2

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\JhI-21 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.06

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval motor neuron | intense | subset

(Ziegler et al., 2016)

glutamatergic neuron | subset

(Ziegler et al., 2016)

larval ventral nerve cord | faint | restricted

(Ziegler et al., 2016)

larval central nervous system

(Ziegler et al., 2016)

early third instar larval stage

embryonic/larval motor neuron | intense | subset

(Ziegler et al., 2016)

wandering third instar larval stage

embryonic/larval neuromuscular junction

(Ziegler et al., 2016)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

JhI-21 is faintly expressed in the cell bodies most neurons, however strong expression is seen in the cell bodies and neuromuscular junctions of ScerGAL4^RapGAP1-OK6 and ScerGAL4^VGlut-OK371 expressing glutamatergic motor neurons. Expression is developmental stage dependent in the motor neurons; cell body expression is strongest during the early third instar larval stage while neuromuscular junction expression appears only at the third instar larval stage. Expression overlaps with that of ScerGAL4^JhI-21.PZ in the motor neurons and part of the brain.

(Ziegler et al., 2016)

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: M{JhI-21-GAL4.Z}

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

neuron of larval brain | restricted

(Ziegler et al., 2016)

embryonic/larval motor neuron | intense | subset

(Ziegler et al., 2016)

glutamatergic neuron

Comment: ventral nerve cord

(Ziegler et al., 2016)

larval ventral nerve cord | restricted

(Ziegler et al., 2016)

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\JhI-21 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\JhI-21

View exonic expression by tissue for Dmel\JhI-21

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0028425

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34624/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0028425

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0028425

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0028425

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG12317

Flygut - An atlas of the Drosophila adult midgut

FBgn0028425

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 11 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of JhI-21

Transgenic constructs containing regulatory region of JhI-21

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene disrupted in

Df(2L)Exel6031

(Ryder, 2004.4.26)

Df(2L)JhI-21

(Ziegler et al., 2016)

Inferred from location ( 11 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal - majority die, with Scer\GAL4^pnr-MD237

JhI-21^GD3466

viable

JhI-21¹³

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

JhI-21^GD3466

viable, with Scer\GAL4^Mef2.PR

JhI-21^GD3466

viable, with Scer\GAL4^tin.CΔ4

JhI-21^GD3466

Other Phenotypes

Allele

abnormal immune response | adult stage

JhI-21^G3331

decreased body size | nutrition conditional, with Scer\GAL4^Ilp2.PR

JhI-21^KK112996

decreased size | larval stage | somatic clone, with Scer\GAL4^Act5C.PI

JhI-21^HMS02271

some die during pupal stage, with Scer\GAL4^pnr-MD237

JhI-21^GD3466

Phenotype manifest in

Allele

embryonic/larval crystal cell | third instar larval stage

JhI-21^G3331

embryonic/larval plasmatocyte | third instar larval stage

JhI-21^G3331

hemocyte | adult stage

JhI-21^G3331

larval brain | larval stage | somatic clone, with Scer\GAL4^Act5C.PI

JhI-21^HMS02271

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (15)

Hsap\SLC7A5

10 of 14

Yes

8 of 14

7 of 14

7 of 14

7 of 14

7 of 14

6 of 14

5 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Hsap\SLC7A5P2

2 of 14

Yes

Hsap\SLC7A14

2 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (17)

Rnor\Slc7a5

10 of 14

Yes

8 of 14

7 of 14

7 of 14

7 of 14

7 of 14

6 of 14

6 of 14

5 of 14

5 of 14

5 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (16)

Mmus\Slc7a5

10 of 14

Yes

8 of 14

7 of 14

7 of 14

7 of 14

7 of 14

6 of 14

6 of 14

5 of 14

5 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (14)

Xtro\slc7a5

6 of 13

Yes

Xtro\slc7a11

6 of 13

Yes

5 of 13

5 of 13

5 of 13

5 of 13

4 of 13

Yes

Xtro\slc7a13

4 of 13

Xtro\LOC100485192

3 of 13

Yes

3 of 13

3 of 13

1 of 13

1 of 13

Yes

Xtro\psmd5

1 of 13

Danio rerio (Zebrafish) (22)

Drer\slc7a5

12 of 14

Yes

8 of 14

8 of 14

7 of 14

7 of 14

7 of 14

7 of 14

7 of 14

Drer\si:dkeyp-120h9.1

6 of 14

6 of 14

6 of 14

6 of 14

2 of 14

2 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (13)

Cele\aat-2

8 of 14

Yes

7 of 14

7 of 14

6 of 14

6 of 14

5 of 14

4 of 14

4 of 14

4 of 14

2 of 14

2 of 14

2 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (13)

Agam\AgaP_AGAP012643

12 of 12

Yes

6 of 12

6 of 12

6 of 12

6 of 12

Yes

Agam\AgaP_AGAP013073

4 of 12

Yes

3 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (14)

Atha\PUT1

5 of 13

Yes

Atha\PUT2

5 of 13

Yes

Atha\PUT4

5 of 13

Yes

Atha\PUT5

5 of 13

Yes

Atha\RMV1

5 of 13

Yes

3 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Saccharomyces cerevisiae (Brewer's yeast) (19)

Scer\MUP1

8 of 13

Yes

Scer\MUP3

8 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (19)

Spom\per1

3 of 12

Yes

Spom\SPAC1039.01

2 of 12

Spom\SPBC15C4.04c

2 of 12

Yes

Spom\SPCC74.04

2 of 12

Yes

Spom\SPCC584.13

2 of 12

Yes

Spom\SPCC794.03

2 of 12

Yes

Spom\thi9

2 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

Spom\SPAPB24D3.02c

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Escherichia coli (enterobacterium) (14)

Ecol\frlA

7 of 11

Yes

Ecol\adiC

3 of 11

Yes

Ecol\cadB

2 of 11

Yes

Ecol\potE

2 of 11

Yes

Ecol\ybaT

2 of 11

Yes

Ecol\ydgI

2 of 11

Yes

Ecol\yjeH

2 of 11

Yes

Ecol\aroP

1 of 11

Ecol\cycA

1 of 11

Ecol\gadC

1 of 11

Yes

1 of 11

1 of 11

1 of 11

1 of 11

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:JhI-21. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (10)

CG1607

11 of 13

mnd

10 of 13

sbm

10 of 13

9 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 2 )

Allele

Disease

Interaction

References

JhI-21^KK112996

ameliorates cancer

modeled by Ras85D^V12.UAS, scrib¹

(Cong et al., 2021)

modeled by Rab5^LL00467, mir-ban^C.UAS.EGFP

(Cong et al., 2021)

JhI-21^HMS02271

ameliorates cancer

modeled by Ras85D^V12.UAS, scrib¹

(Cong et al., 2021)

modeled by Rab5^LL00467, mir-ban^C.UAS.EGFP

(Cong et al., 2021)

ameliorates brain cancer

modeled by brat^KK113206

(Rebelo and Homem, 2023)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SLC7A5; solute carrier family 7 member 5

10 of 14

600182

SLC7A8; solute carrier family 7 member 8

8 of 14

604235

SLC7A6; solute carrier family 7 member 6

7 of 14

605641

SLC7A9; solute carrier family 7 member 9

7 of 14

604144

CYSTINURIA

cystinuria

SLC7A10; solute carrier family 7 member 10

7 of 14

607959

SLC7A11; solute carrier family 7 member 11

7 of 14

607933

SLC7A7; solute carrier family 7 member 7

6 of 14

603593

LYSINURIC PROTEIN INTOLERANCE; LPI

lysinuric protein intolerance

SLC7A13; solute carrier family 7 member 13

5 of 14

617256

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Ras85D|scrib

suppressible

JhI-21

(Cong et al., 2021)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0028425

MIST (protein-protein) - An integrated Molecular Interaction Database

34624

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

Tryptophan catabolism

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

mTOR signaling pathway

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-46

Cytogenetic map

33B11-33C1

Sequence location

2L:12,051,755..12,056,042 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

33B11-33C1

Limits computationally determined from genome sequence between P{PZ}l(2)01810⁰¹⁸¹⁰&P{EP}CG6785^EP340 and P{EP}JhI-21^EP1187

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

33C1-33C2

(Dubrovsky, 2000.5.30)

Experimentally Determined Recombination Data

Location

2-46

(FlyBase, 2016)

2-39.3

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (18)

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (124)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD39658

Other clones

DPiM_LD39658

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0028425

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0028425

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Ziegler et al., 2016)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: JhI-21 CG12317

(FlyBase, 1996-)

Additional comments

Source for merge of JhI-21 CG12317 was sequence comparison ( date:010602 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG12317

(National Institute of Genetics Fly Stocks, 2022-, Paik et al., 2017, Limmer et al., 2014, Christis and Munro, 2012, Mosallanejad et al., 2010, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Reynolds et al., 2009, Augustin et al., 2007)

JHI-21

(Manière et al., 2020, Jin et al., 2008)

JhI21

(Li et al., 2023)

Jhl-21

(Ayroles et al., 2009, Jin et al., 2008)

jhl-21

(Nishida et al., 2021)

Name Synonyms

JhI-21

Juvenile hormone Inducible-21

(Shafer, 2025, Ziegler et al., 2016)

solute carrier 7-family amino acid transporter

(Ro et al., 2016)

Secondary FlyBase IDs

FBgn0032403

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 55 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

34624

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VKC2

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9VKC2

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VKC2

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0028425

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34624/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0028425

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0028425

FlyMine - An integrated database for Drosophila genomics

FBgn0028425

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG12317

MARRVEL_MODEL - MARRVEL (model organism gene)

34624

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0028425

DroID - A comprehensive database of gene and protein interactions.

FBgn0028425

DRSC - Results frm RNAi screens

FBgn0028425

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0028425

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0028425

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG12317

Flygut - An atlas of the Drosophila adult midgut

FBgn0028425

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC013142

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

mTOR signaling pathway

MIST (protein-protein) - An integrated Molecular Interaction Database

34624

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

Tryptophan catabolism

References (82)

The following external sites may use different assemblies or annotations than FlyBase.

0.06

Report Sections