FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: SEPARASES
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General Information
Name
SEPARASES
Species
D. melanogaster
Symbol
SSE
FlyBase ID
FBgg0001412
Date last reviewed
2020-06-08
Number of members
1
Description
Description
Separases are cysteine-type endopeptidases that belong to MEROPS family C50. They degrade a conserved cohesin subunit during mitosis, thereby allowing sister chromatid separation. (Adapted from FBrf0139669.)
Notes on Group

The SEPARASES gene group contains only one member.

Source Material
The SEPARASES Gene Group has been compiled using the following publication(s): Jager et al., 2001 and Rawlings and Barrett, 1996- .
Key Gene Ontology (GO) terms
Molecular Function
cysteine-type endopeptidase activity
Biological Process
mitotic sister chromatid segregation
proteolysis
Cellular Component
Enzymatic activity
Enzyme name (EC)
3.4.22.-
Related Gene Groups
Parent group(s)
CYSTEINE PEPTIDASES
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)

[MEROPS Family C50](https://www.ebi.ac.uk/merops/cgi-bin/famsum?family=c50)

Synonyms and Secondary IDs
Synonym(s)
SSE
SEPARASES
Secondary FlyBase ID(s)
References (4)