FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mGluRUbi.combs.Tag:FLAG,VHH05-tag
Open Close
General Information
Symbol
Dmel\mGluRUbi.combs.Tag:FLAG,VHH05-tag
Species
D. melanogaster
Name
FlyBase ID
FBal0405418
Feature type
allele
Associated gene
Dmel\mGluR
Associated Insertion(s)
Carried in Construct
P{Ubi-mGluR.combs}
Key Links
Transgenic product class
synonymous_variant
(Stewart et al., 2024)
wild_type
(Stewart et al., 2024)
Mutagen
Nature of the Allele
Transgenic product class
synonymous_variant
(Stewart et al., 2024)
wild_type
(Stewart et al., 2024)
Mutagen
in vitro construct
(Stewart et al., 2024)
Progenitor genotype
Carried in construct
P{Ubi-mGluR.combs}
Cytology
Description

A Ubiquitin promoter drives expression of the mGluR coding sequence that is tagged at the N-terminal end with Tag:FLAG and at the C-terminal end with 3xVHH05-tag. The codon usage of the mGluR coding sequence has been modified (by synonymous codon substitutions) so that the codons correspond to the most commonly used synonymous codon in the D. melanogaster genome, except where most of the orb2 binding sites in the mRNA are, which have the codons of the endogenous sequence, resulting in 26 orb2 binding sites being present in the mRNA.

(Stewart et al., 2024)
Allele components
Component
Use(s)
Encoded product / tool
mGluR
Tagged with
Tag:FLAG
VHH05-tag
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mGluRUbi.combs.Tag:FLAG,VHH05-tag
      Name Synonyms
      Secondary FlyBase IDs
        References (1)