FlyBase Allele Report: Dmel\Src64B[UAS.cUa]

General Information

Symbol

Dmel\Src64B^UAS.cUa

Species

D. melanogaster

Name

UAS construct a of Unknown

FlyBase ID

FBal0360453

Feature type

allele

Associated gene

Dmel\Src64B

Associated Insertion(s)

Carried in Construct

P{UAS-Src64B.U}

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Src64B.U}

Cytology

Description

UAS regulatory sequences drive expression of Src64B.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Src64B

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of intestinal cancer

CEA

(Kohlmaier et al., 2015)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of intestinal cancer

is ameliorated by Egfr^RNAi.UAS.cUa

(Kohlmaier et al., 2015)

is ameliorated by Stat92E^RNAi.UAS.cUa

(Kohlmaier et al., 2015)

is ameliorated by Egfr^RNAi.UAS.cUa

(Kohlmaier et al., 2015)

is ameliorated by Stat92E^RNAi.UAS.cUa

(Kohlmaier et al., 2015)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult midgut, with Scer\GAL4^NP7397

(Kohlmaier et al., 2015)

gut epithelial section, with Scer\GAL4^NP0001

(Kohlmaier et al., 2015)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^NP7397, Src64B^UAS.cUa has increased occurrence of cell division | adult stage phenotype, suppressible | partially by Mkp3^UAS.cUa, Scer\GAL4^NP7397

(Kohlmaier et al., 2015)

Scer\GAL4^NP7397, Src64B^UAS.cUa has increased occurrence of cell division | adult stage phenotype, suppressible by Egfr^RNAi.UAS.cUa, Scer\GAL4^NP7397

(Kohlmaier et al., 2015)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^NP7397, Src64B^UAS.cUa has adult midgut phenotype, suppressible | partially by Mkp3^UAS.cUa, Scer\GAL4^NP7397

(Kohlmaier et al., 2015)

Scer\GAL4^NP7397, Src64B^UAS.cUa has adult midgut phenotype, suppressible by Egfr^RNAi.UAS.cUa, Scer\GAL4^NP7397

(Kohlmaier et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Src64B^UAS.cUa

Name Synonyms

UAS construct a of Unknown

Secondary FlyBase IDs

References (3)

Report Sections

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