FlyBase Allele Report: Dmel\Ndfip[UAS.Tag:FLAG]

General Information

Symbol

Dmel\Ndfip^UAS.Tag:FLAG

Species

D. melanogaster

Name

FlyBase ID

FBal0345640

Feature type

allele

Associated gene

Dmel\Ndfip

Associated Insertion(s)

Carried in Construct

P{UAS-Ndfip.FLAG}

Key Links

Transgenic product class

cDNA

(Li et al., 2018)

wild_type

(Li et al., 2018)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Li et al., 2018)

wild_type

(Li et al., 2018)

Mutagen

in vitro construct

(Li et al., 2018)

Progenitor genotype

Carried in construct

P{UAS-Ndfip.FLAG}

Cytology

Description

UASt regulatory sequences drive expression of Ndfip cDNA, tagged with Tag:FLAG at the N-terminus.

(Li et al., 2018)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Ndfip

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates brain cancer

modeled by Vps35^E42

(Li et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 1 )

Coexpression of Ndfip^UAS.Tag:FLAG and Su(dx)^UAS.cCa is required to rescue the brain tumor phenotype observed in Vps35^E42 mutants .

(Li et al., 2018)

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-enhancer of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-enhancer of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-enhancer of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-enhancer of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Suppressor of

Statement

Reference

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG is a suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG is a suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

NOT Suppressor of

Statement

Reference

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-suppressor of increased cell number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Other

Statement

Reference

Ndfip^UAS.Tag:FLAG, Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa has abnormal neuroanatomy | larval stage phenotype

(Li et al., 2018)

Ndfip^UAS.Tag:FLAG, Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa has increased cell number | larval stage phenotype

(Li et al., 2018)

Ndfip^UAS.Tag:FLAG, Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa has atrophy | larval stage phenotype

(Li et al., 2018)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-enhancer of larval neuroblast | larval stage | increased number phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-enhancer of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-enhancer of larval neuroblast | larval stage | increased number phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-enhancer of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-enhancer of larval neuroblast | larval stage | increased number phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-enhancer of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-enhancer of larval neuroblast | larval stage | increased number phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-enhancer of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Suppressor of

Statement

Reference

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG is a suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG is a suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

NOT Suppressor of

Statement

Reference

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Nedd4^{UAS.cLa.Tag:MYC}, Ndfip^UAS.Tag:FLAG is a non-suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Ndfip^UAS.Tag:FLAG, Hrs^HMS00840 is a non-suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa, Hrs^HMS00841, Ndfip^UAS.Tag:FLAG is a non-suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-suppressor of larval neuroblast | increased number | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Scer\GAL4^insc-Mz1407/Ndfip^UAS.Tag:FLAG is a non-suppressor of larval brain | larval stage phenotype of Vps35^E42

(Li et al., 2018)

Other

Statement

Reference

Ndfip^UAS.Tag:FLAG, Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa has larval neuron phenotype

(Li et al., 2018)

Ndfip^UAS.Tag:FLAG, Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa has larval brain | larval stage phenotype

(Li et al., 2018)

Ndfip^UAS.Tag:FLAG, Scer\GAL4^insc-Mz1407, Su(dx)^UAS.cCa has type II neuroblast | larval stage phenotype

(Li et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expressing Su(dx)^UAS.cCa and Ndfip^UAS.Tag:FLAG under the control of Scer\GAL4^pnt-14-94 results in a decrease in type II neuroblast lineages in the larval brain, associated with brain atrophy.

(Li et al., 2018)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Ndfip^UAS.Tag:FLAG

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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