FlyBase Allele Report: Scer\GAL4[nrv2.PU]

General Information

Symbol

Scer\GAL4^nrv2.PU

Species

S. cerevisiae

Name

Nervana 2 promoter construct of Unknown

FlyBase ID

FBal0318367

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{nrv2-GAL4.U}

Also Known As

nrv2-Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{nrv2-GAL4.U}

Cytology

Description

nrv2 regulatory sequences control expression of a GAL4 driver.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

nrv2

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval wrapping glial cell

(Otto et al., 2018)

embryonic/larval cell body glial cell

(Otto et al., 2018)

embryonic/larval ensheathing glial cell

(Otto et al., 2018)

embryonic/larval astrocyte-like glial cell

(Otto et al., 2018)

Additional Information

Statement

Reference

Marker for

embryonic/larval astrocyte-like glial cell

(Otto et al., 2018)

embryonic/larval cell body glial cell

(Otto et al., 2018)

embryonic/larval ensheathing glial cell

(Otto et al., 2018)

embryonic/larval wrapping glial cell

(Otto et al., 2018)

Reflects expression of

nrv2

(Otto et al., 2018)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage | progressive, with Hsap\ATXN1^82Q.UAS

(Al-Ramahi et al., 2007)

abnormal locomotor behavior | adult stage | progressive, with Hsap\HTT^NT.128Q.UAS

(Al-Ramahi et al., 2007)

abnormal locomotor behavior | third instar larval stage, with Dvir\GJ19049^UAS.cOa

(Otto et al., 2018)

abnormal locomotor behavior | third instar larval stage, with shop^NIG.7280R

(Otto et al., 2018)

abnormal memory | adult stage, with klg^GD2555

(Matsuno et al., 2015)

abnormal memory | adult stage, with klg^GD14314

(Matsuno et al., 2015)

abnormal memory | adult stage, with Pcb^UAS.cYa

(Yamazaki et al., 2014)

abnormal memory | adult stage, with Sod1^RNAi.UAS.cUa

(Yamazaki et al., 2014)

abnormal neuroanatomy | P-stage, with egr^{TH201501125.S}

(Zheng et al., 2025)

abnormal neuroanatomy | P-stage, with Scer\GAL4^NP6293, Scer\GAL4^moody.PU, egr^{TH201501125.S}

(Zheng et al., 2025)

abnormal neurophysiology | third instar larval stage, with shop^NIG.7280R

(Otto et al., 2018)

short lived, with Hsap\ATXN1^82Q.UAS

(Al-Ramahi et al., 2007)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^nrv2.PU, shop^KK107994 has abnormal locomotor behavior | third instar larval stage phenotype, enhanceable by Orco^RNAi.UAS.cUa, Scer\GAL4^nrv2.PU

(Otto et al., 2018)

Suppressed by

Statement

Reference

Scer\GAL4^nrv2.PU, shop^KK107994 has abnormal locomotor behavior | third instar larval stage phenotype, suppressible by Dvir\GJ19049^UAS.cOa, Scer\GAL4^nrv2.PU

(Otto et al., 2018)

Hsap\ATXN1^82Q.UAS, Scer\GAL4^nrv2.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by Atx2^X1

(Al-Ramahi et al., 2007)

Hsap\ATXN1^82Q.UAS, Scer\GAL4^nrv2.PU has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible | partially by Atx2^X1/Atx2[+]

(Al-Ramahi et al., 2007)

Hsap\ATXN1^82Q.UAS, Scer\GAL4^nrv2.PU has short lived phenotype, suppressible | partially by Atx2^X1/Atx2[+]

(Al-Ramahi et al., 2007)

NOT suppressed by

Statement

Reference

Scer\GAL4^nrv2.PU, Sod1^RNAi.UAS.cUa has abnormal memory | adult stage phenotype, non-suppressible by Pcb^EP2547/PCB[+]

(Yamazaki et al., 2014)

Hsap\HTT^NT.128Q.UAS, Scer\GAL4^nrv2.PU has abnormal locomotor behavior | adult stage | progressive phenotype, non-suppressible by Atx2^X1/Atx2[+]

(Al-Ramahi et al., 2007)

Enhancer of

Statement

Reference

Orco^RNAi.UAS.cUa, Scer\GAL4^nrv2.PU is an enhancer of abnormal locomotor behavior | third instar larval stage phenotype of Scer\GAL4^nrv2.PU, shop^KK107994

(Otto et al., 2018)

Suppressor of

Statement

Reference

Dvir\GJ19049^UAS.cOa, Scer\GAL4^nrv2.PU is a suppressor of abnormal locomotor behavior | third instar larval stage phenotype of Scer\GAL4^nrv2.PU, shop^KK107994

(Otto et al., 2018)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^nrv2.PU/CPT2^UAS.cSa rescues CPT2^δ3

(Schulz et al., 2015)

Scer\GAL4^nrv2.PU/Pcb^UAS.cYa rescues Pcb^EP2547/PCB[+]

(Yamazaki et al., 2014)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^nrv2.PU

Name Synonyms

Nervana 2 promoter construct of Unknown

Secondary FlyBase IDs

References (23)

Report Sections

Open Close