FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\InvadolysinUAS.N.Tag:HA
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General Information
Symbol
Dmel\InvadolysinUAS.N.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0298990
Feature type
allele
Associated gene
Dmel\Invadolysin
Associated Insertion(s)
Carried in Construct
P{UAS-HA-Invadolysin}
Key Links
Transgenic product class
wild_type
(Di Cara et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Di Cara et al., 2013)
Mutagen
in vitro construct
(Di Cara et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-HA-Invadolysin}
Cytology
Description

UASt regulatory sequences drive expression of full-length Invadolysin coding sequences tagged at the N-terminal with Tag:HA.

(Di Cara et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Invadolysin
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of InvadolysinScer\UAS.N.T:Ivir\HA1 in adult eyes, under the control of Scer\GAL4GMR.PF at 29[o]C results in a rough eye phenotype. Ommatidia in these eyes demonstrate tissue degradation and empty bristle sockets.

      (Di Cara et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, enhanceable by blwKG05893

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has ommatidium | temperature conditional phenotype, enhanceable by blwKG05893

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has interommatidial bristle | temperature conditional phenotype, enhanceable by blwKG05893

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, enhanceable by blwEY08188

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has ommatidium | temperature conditional phenotype, enhanceable by blwEY08188

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has interommatidial bristle | temperature conditional phenotype, enhanceable by blwEY08188

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has eye | temperature conditional phenotype, enhanceable by SNF4AγEP3015b

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has ommatidium | temperature conditional phenotype, enhanceable by SNF4AγEP3015b

      (Di Cara et al., 2013)

      InvadolysinUAS.N.Tag:HA, Scer\GAL4GMR.PF has interommatidial bristle | temperature conditional phenotype, enhanceable by SNF4AγEP3015b

      (Di Cara et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A blwKG05893 or blwEY08188 mutant background enhances the rough eye phenotype seen in adult eyes upon expression of InvadolysinScer\UAS.N.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF at 29[o]C.

      The rough eye phenotype seen upon expression of InvadolysinScer\UAS.N.T:Ivir\HA1 at 29[o]C under the control of Scer\GAL4GMR.PF, is enhanced by a heterozygous SNF4AγEP3015b background.

      (Di Cara et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      InvadolysinUAS.N.Tag:HA is rescued by Scer\GAL4GMR.PF/Invadolysin4Y7

      (Di Cara et al., 2013)
      Comments

      The rough eye seen upon expression of InvadolysinScer\UAS.N.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF at 29[o]C is suppressed in a Invadolysin4Y7 mutant background.

      (Di Cara et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      InvadolysinScer\UAS.N.T:Ivir\HA1
      InvadolysinUAS.N.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)