FlyBase Allele Report: Dmel\ND-75[HMS00854]

General Information

Symbol

Dmel\ND-75^HMS00854

Species

D. melanogaster

Name

FlyBase ID

FBal0257534

Feature type

allele

Associated gene

Dmel\ND-75

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00854}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00854}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00854

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of nuclear type mitochondrial complex I deficiency 5

CEA

(Granat et al., 2023)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal, with Scer\GAL4^eya.enh1+E+2

(Pletcher et al., 2019)

visible | adult stage, with Scer\GAL4^eya.enh1+E+2

(Pletcher et al., 2019)

Phenotype Manifest In

embryonic/larval dorsal tracheal branch | larval stage, with Scer\GAL4^drm.7.1

(Hudson et al., 2023)

eye, with Scer\GAL4^eya.enh1+E+2

(Pletcher et al., 2019)

Detailed Description

Statement

Reference

Expression under the control of Scer\GAL4^eya.enh1+E+2 results in a glossy eye phenotype.

(Pletcher et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

ND-75^HMS00854, Scer\GAL4^drm.7.1 is a non-enhancer of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

ND-75^HMS00854, Scer\GAL4^drm.7.1 is a non-enhancer of embryonic/larval dorsal tracheal branch | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

NOT Suppressor of

Statement

Reference

ND-75^HMS00854, Scer\GAL4^drm.7.1 is a non-suppressor of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

ND-75^HMS00854, Scer\GAL4^drm.7.1 is a non-suppressor of embryonic/larval dorsal tracheal branch | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

Other

Statement

Reference

ND-75^HMS00854, Scer\GAL4^drm.7.1, trc^GL01127 has embryonic/larval dorsal tracheal branch | larval stage phenotype

(Hudson et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

33911

y¹ v¹; P{TRiP.HMS00854}attP2

NIG-Fly

HMS00854

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00854}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ND-75^HMS00854

ND75^HMS00854

ND75^RNAi-strong

(Owusu-Ansah et al., 2013)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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