FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\diaUASp.EGFP
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General Information
Symbol
Dmel\diaUASp.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0230299
Feature type
allele
Associated gene
Dmel\dia
Associated Insertion(s)
Carried in Construct
P{UASp-dia.EGFP}
Also Known As
UAS-dia-GFP, UAS-dia::GFP, GFP-Dia, UAS-Dia:GFP, UAS-dia::EGFP
Key Links
Transgenic product class
wild_type
(Homem and Peifer, 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Homem and Peifer, 2008)
Mutagen
in vitro construct
(Homem and Peifer, 2008)
Progenitor genotype
Carried in construct
P{UASp-dia.EGFP}
Cytology
Description

UASp regulatory sequences drive expression of the dia which is tagged at the N-terminal end with EGFP (the tag is joined to the dia coding region via a HRYTSLYKKAGSAAAPFT linker).

(Homem and Peifer, 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
dia
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  cancer
      modeled by MycαTub84B.PBb
      (Levayer et al., 2015)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of diaScer\UAS.T:Avic\GFP-EGFP in the 'loser' cells suppresses the increase in wild type 'loser' clone splitting and reduced clone compactness seen when cell competition is induced through generation of super-competitive MycαTub84B.PBb-expressing clones.

      Expression of diaScer\UAS.T:Avic\GFP-EGFP in 'loser' cells suppresses the elimination usually seen when cell competition is induced through generation of wild type clones in MycαTub84B.PBb-expressing tissue. The reduction in the maximum speed of relaxation of junctions in loser-loser and loser-winner junctions after laser nanoablation is also suppressed when diaScer\UAS.T:Avic\GFP-EGFP is expressed in loser cells.

      (Levayer et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      diaUASp.EGFP/Scer\GAL4e22c partially rescues diaunspecified

      (Homem and Peifer, 2008)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      diaScer\UAS.T:Avic\GFP-EGFP
      diaUASp.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (26)