FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CenG1AEY01217
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General Information
Symbol
Dmel\CenG1AEY01217
Species
D. melanogaster
Name
FlyBase ID
FBal0217099
Feature type
allele
Associated gene
Dmel\CenG1A
Associated Insertion(s)
P{EPgy2}CenG1AEY01217
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EPgy2}CenG1AEY01217
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{EPgy2}
    Regulatory region(s)
    UASp
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  fragile X syndrome
        modeled by Fmr1Δ50M
        (Gross et al., 2015)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Flies heterozygous for CenG1AEY01217 have impaired short-term memory.

        (Gross et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        CenG1A[+]/CenG1AEY01217 is a suppressor of partially lethal - majority die phenotype of Fmr1Δ50M

        (Gross et al., 2015)

        CenG1A[+]/CenG1AEY01217 is a suppressor of abnormal neuroanatomy phenotype of Fmr1Δ50M

        (Gross et al., 2015)
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        CenG1A[+]/CenG1AEY01217 is a suppressor of adult mushroom body beta-lobe phenotype of Fmr1Δ50M

        (Gross et al., 2015)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Heterozygous CenG1AEY01217 increases the viability of flies homozygous for Fmr1Δ50M.

        Heterozygosity for CenG1AEY01217 suppresses the mushroom body phenotype of beta-lobe fusion and the impaired short-term memory defect in homozygous Fmr1Δ50M flies.

        (Gross et al., 2015)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CenG1AEY01217
        (Odierna et al., 2020, Matsumoto et al., 2018, Gross et al., 2015)
        cenG1AEY01217
        Name Synonyms
        Secondary FlyBase IDs
          References (4)