FlyBase Allele Report: Dmel\org-1[N+T+C.UAS.Tag:HA]

General Information

Symbol

Dmel\org-1^{N+T+C.UAS.Tag:HA}

Species

D. melanogaster

Name

FlyBase ID

FBal0178561

Feature type

allele

Associated gene

Dmel\org-1

Associated Insertion(s)

Carried in Construct

P{UAS-org-1.N+T+C.HA}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Porsch et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-org-1.N+T+C.HA}

Cytology

Description

The org-1 N, T and C domains have been fused in order separated by two or three junctional amino acids (A,G or T). Tag:HA tags are at the C and N termini. Expression of this construct is driven by UASt sequences.

(Porsch et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

org-1

Tagged with

Tag:HA

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

antenna, with Scer\GAL4^dpp.blk1

(Porsch et al., 2005)

arista, with Scer\GAL4^dpp.blk1

(Porsch et al., 2005)

eye, with Scer\GAL4^dpp.blk1

(Porsch et al., 2005)

interommatidial bristle, with Scer\GAL4^GMR.PF

(Porsch et al., 2005)

macrochaeta | ectopic, with Scer\GAL4^dpp.blk1

(Porsch et al., 2005)

third segment of antenna, with Scer\GAL4^dpp.blk1

(Porsch et al., 2005)

unguis | ectopic, with Scer\GAL4^dpp.blk1

(Porsch et al., 2005)

Detailed Description

Statement

Reference

When org-1^{N+T+C.Scer\UAS.T:Ivir\HA1} is driven by Scer\GAL4^dpp.blk1 normal or slightly enlarged eyes are seen. When org-1^{N+T+C.Scer\UAS.T:Ivir\HA1} is driven by Scer\GAL4^dpp.blk1, mutant antennae are defective. The third antennal segment contains ectopic bristles at its distal part. The arista is transformed into tarsal structures with a claw at the distal end. When org-1^{N+T+C.Scer\UAS.T:Ivir\HA1} is driven by Scer\GAL4^GMR.PF A loss of interommatidial bristles is seen, but ommatidial development appears normal.

(Porsch et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

org-1^{N+T+C.Scer\UAS.T:Ivir\HA1}

org-1^{N+T+C.UAS.Tag:HA}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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