FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\FaddEY10870
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General Information
Symbol
Dmel\FaddEY10870
Species
D. melanogaster
Name
FlyBase ID
FBal0162773
Feature type
allele
Associated gene
Dmel\Fadd
Associated Insertion(s)
P{EPgy2}FaddEY10870
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}FaddEY10870
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous and hemizygous flies are resistant to V. cholerae infection compared to controls.

      24 hours after infection with V. cholerae, the bacterial load of homozygous mutants is comparable to or greater than controls - resistance is not the result of decreased colonization.

      (Berkey et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Fadd[+]/FaddEY10870 is an enhancer of phenotype of Sindbis\repUAS.GFP

      (Avadhanula et al., 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Heterozygosity for FaddEY10870 in a Scer\GAL4Act5C.PI Zzzz\repScer\UAS.T:Avic\GFP background results in increased Sindbis viral replication.

      (Avadhanula et al., 2009)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      BG4EY10870
      FaddEY10870
      Faddey10870
      (Avadhanula et al., 2009)
      faddEY10870
      (Berkey et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)