FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\PclEY08457
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General Information
Symbol
Dmel\PclEY08457
Species
D. melanogaster
Name
FlyBase ID
FBal0160041
Feature type
allele
Associated gene
Dmel\Pcl
Associated Insertion(s)
P{EPgy2}PclEY08457
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}PclEY08457
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  amyotrophic lateral sclerosis type 8
      modeled by Vap33P58S.UAS.Tag:FLAG
      (Sanhueza et al., 2015)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Pcl[+]/PclEY08457 is an enhancer of visible | adult stage phenotype of Marcal1UAS.cBa, Scer\GAL4Tub.PU

      (Morimoto et al., 2016)

      Pcl[+]/PclEY08457 is an enhancer of visible | adult stage phenotype of Hsap\SMARCAL1UAS.cBa, Scer\GAL4Bx-MS1096

      (Morimoto et al., 2016)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Pcl[+]/PclEY08457 is an enhancer of wing vein | adult stage phenotype of Marcal1UAS.cBa, Scer\GAL4Tub.PU

      (Morimoto et al., 2016)

      Pcl[+]/PclEY08457 is an enhancer of wing vein | adult stage phenotype of Hsap\SMARCAL1UAS.cBa, Scer\GAL4Bx-MS1096

      (Morimoto et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The formation of ectopic wing veins observed in adult flies expressing Marcal1Scer\UAS.cBa under the control of Scer\GAL4tub.PU is exacerbated by combination with a single copy of PclEY08457.

      (Morimoto et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference

      The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1Scer\UAS.cBa under the control of Scer\GAL4Bx-MS1096 is exacerbated by combination with a single copy of PclEY08457.

      (Morimoto et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      PclEY08457
      (Ji et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)