FlyBase Allele Report: Dmel\Ras85D[unspecified]

General Information

Symbol

Dmel\Ras85D^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0089554

Feature type

allele

Associated gene

Dmel\Ras85D

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates neurofibromatosis

modeled by Nf1^E2

(Walker et al., 2006)

Comments on Models/Modifiers Based on Experimental Evidence ( 1 )

One copy of Ras85D^unspecified ameliorates the size defects seen in Nf1^E2 mutant flies in Nf1^E2 when in combination with phl¹²/+.

(Walker et al., 2006)

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Therrien et al., 2000)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ras85D[+]/Ras85D^unspecified is an enhancer of lethal phenotype of Raf¹²

(Therrien et al., 2000)

Ras85D[+]/Ras85D^unspecified is an enhancer of visible phenotype of ksr::tor^{ΔNksr.hs.sev}

(Therrien et al., 2000)

Suppressor of

Statement

Reference

phl[+], Raf¹², Ras85D[+], Ras85D^unspecified is a suppressor | partially of decreased body size | pupal stage phenotype of Nf1^E2

(Walker et al., 2006)

NOT Suppressor of

Statement

Reference

Ras85D[+]/Ras85D^unspecified is a non-suppressor of decreased body size | pupal stage phenotype of Nf1^E2

(Walker et al., 2006)

Ras64B^unspecified, Ras85D[+], Ras85D^unspecified is a non-suppressor of decreased body size | pupal stage phenotype of Nf1^E2

(Walker et al., 2006)

Dsor1[+], Ras85D[+], Ras85D^unspecified, Dsor1^S-1221 is a non-suppressor of decreased body size | pupal stage phenotype of Nf1^E2

(Walker et al., 2006)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ras85D^unspecified has phenotype, suppressible by aop^S2382

(Rebay and Rubin, 1995)

Enhancer of

Statement

Reference

Ras85D[+]/Ras85D^unspecified is an enhancer of eye phenotype of ksr::tor^{ΔNksr.hs.sev}

(Therrien et al., 2000)

Ras85D^unspecified is an enhancer of phenotype of PTP-ER^hs.sev

(Karim and Rubin, 1999)

NOT Enhancer of

Statement

Reference

Ras85D^unspecified is a non-enhancer of phenotype of Hsap\RALA^G23V.GMR

(Sawamoto et al., 1999)

Suppressor of

Statement

Reference

Ras85D[+]/Ras85D^unspecified is a suppressor of wing vein | ectopic phenotype of Egfr^E1

(Li and Li, 2003)

Ras85D[+]/Ras85D^unspecified is a suppressor of photoreceptor cell R8 | increased number phenotype of ed^4.12

(Rawlins et al., 2003)

NOT Suppressor of

Statement

Reference

Ras85D^unspecified is a non-suppressor of phenotype of Hsap\RALA^G23V.GMR

(Sawamoto et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The ed^4.12 R8 cell twinning phenotype is strongly suppressed by Ras85D^unspecified/+.

(Rawlins et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Ras85D^unspecified

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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