FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Asxunspecified
Open Close
General Information
Symbol
Dmel\Asxunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0055350
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Mutant embryos show the transformation of the thorax to the first abdominal segment and the abdominal segments to more posterior ones.

    Homozygous embryos show partial transformation of head and thorax into abdominal structures, and partial transformation of abdominal segment A8 into A7. Heterozygous adult males show sex combs on the second and third legs with low penetrance.

    Embryos have head defects, with a transformation of head, thorax and abdomen segments into more posterior structures. In Psc1 Asxunspecified double mutants, all denticle bands are similar to each other, and resemble A8 of wild-type embryos, although the thorax appears less transformed as the Keilin's organs are present. Head involution does not occur. A prominent abdominal denticle appears on the dorsal surface of the head and a few abdominal denticles are found behind the floor of the pharynx. Psc1 Asxunspecified Pclunspecified triple mutant embryos are characterised by a tandem array of posterior abdominal segments including up to four abdominal denticle bands in the head region. This phenotype is suppressed in embryos also lacking the bithorax complex region.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The transformation seen in Asxunspecified heterozygotes is dominantly enhanced by Su(z)121, giving additional sex comb teeth on the second and third legs in male double heterozygous flies.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (6)