FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\scB5
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General Information
Symbol
Dmel\scB5
Species
D. melanogaster
Name
FlyBase ID
FBal0051175
Feature type
allele
Associated gene
Dmel\sc
Associated Insertion(s)
Carried in Construct
P{B5.T4+,w+}
Key Links
Transgenic product class
genomic_DNA
(Erickson and Cline, 1991)
wild_type
(Erickson and Cline, 1991)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Erickson and Cline, 1991)
wild_type
(Erickson and Cline, 1991)
Mutagen
in vitro construct
(Erickson and Cline, 1991)
Progenitor genotype
Carried in construct
P{B5.T4+,w+}
Cytology
Description

10.5kb genomic fragment containing the sc gene.

(Erickson and Cline, 1991)
Allele components
Component
Use(s)
Regulatory region(s)
sc
Encoded product / tool
sc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Causes male lethality by activating Sxl in haplo-X flies.

      (Erickson and Cline, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      scB5 is a suppressor of lethal | female phenotype of sisA1

      (Erickson and Cline, 1991)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Suppresses the sisA1 female-specific lethality phenotype. Two copies of P{B5.T4+,w+} are more effective at the suppression than one.

      (Erickson and Cline, 1991)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      scB5 partially rescues scsisB-1

      (Erickson and Cline, 1991)
      Comments

      Complements the female-specific lethality of scsisB-1, but not the bristle phenotype.

      (Erickson and Cline, 1991)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      scB5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)