FlyBase Allele Report: Dmel\Cdk4[s4639]

General Information

Symbol

Dmel\Cdk4^s4639

Species

D. melanogaster

Name

FlyBase ID

FBal0009318

Feature type

allele

Associated gene

Dmel\Cdk4

Associated Insertion(s)

P{lacW}Cdk4^s4639

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{lacW}Cdk4^s4639

Cytology

Description

The P{lacW} insertion is in the second exon of the translated region of the Cdk4 gene.

(Meyer et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Cdk4^s4639 is a non-enhancer of visible phenotype of upd1^GMR.PB

(Mukherjee et al., 2006)

NOT Suppressor of

Statement

Reference

Cdk4[+]/Cdk4^s4639 is a non-suppressor of increased cell death phenotype of shtd¹

(Tanaka-Matakatsu et al., 2007)

Cdk4^s4639 is a non-suppressor of visible phenotype of upd1^GMR.PB

(Mukherjee et al., 2006)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Cdk4^s4639 is a non-enhancer of eye phenotype of upd1^GMR.PB

(Mukherjee et al., 2006)

NOT Suppressor of

Statement

Reference

Cdk4[+]/Cdk4^s4639 is a non-suppressor of eye phenotype of shtd¹

(Tanaka-Matakatsu et al., 2007)

Cdk4[+]/Cdk4^s4639 is a non-suppressor of ommatidium phenotype of shtd¹

(Tanaka-Matakatsu et al., 2007)

Cdk4^s4639 is a non-suppressor of eye phenotype of upd1^GMR.PB

(Mukherjee et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

Cdk4⁰⁵⁴²⁸

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

12056

w¹¹¹⁸; P{lacW}Cdk4^s4639/CyO

Kyoto

108880

w¹¹¹⁸; P{lacW}Cdk4^s4639/CyO

111376

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}Cdk4^s4639 /CyO y⁺

Notes on Origin

Discoverer

M. Scott.

Comments

Complements: Sema-2a⁰³⁰²¹. Complements: Dek⁰⁴¹⁵⁴. Complements: Hmgs⁰⁶²¹⁴.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Cdk4^s4639

(Sainz de la Maza et al., 2022, Baumgardt et al., 2014, Tanaka-Matakatsu et al., 2007)

l(2)s4639

(Spradling et al., 1999)

l(2)s4639^s4639

(BDGP Project Members, 1994-1999)

s4639

(Mukherjee et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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