FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kisS
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General Information
Symbol
Dmel\kisS
Species
D. melanogaster
Name
of Spradling
FlyBase ID
FBal0005692
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous clones in the fifth adult abdominal segment show transformation to a more anterior identity, as shown by the loss of the black pigmentation characteristic of this segment. The effect is cell autonomous. The average size and frequency of homozygous clones induced at the cellular blastoderm stage are not significantly reduced in any body segments relative to control clones. Homozygous clones in the anterior compartment of the first leg show a reduction in the transverse row of bristles and the number of sex comb teeth. Clones in the first leg can also show an apical bristle (a characteristic of the second leg) at the distal end of the tibia. Clones in the second leg have no phenotypic abnormalities. Clones in the third leg show abnormalities, particularly in the distal leg structures; the femur and tibia are slightly abnormal, while the tarsal segments are severely distorted. All five tarsal segments are present but are truncated and have a hooked shape. Homozygous kisS embryos derived from homozygous kisS female germline clones (lacking both maternal and zygotic kis function) have a similar, but less severe phenotype than homozygous kis1 embryos derived from homozygous kis1 female germline clones.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Spradling.

Comments
Comments

Revertable at high frequency in the presence of P-element transposase.

kisS is revertible to wild type upon providing P\T function, indicating that the P{ry11} insertion causes the kisS mutation.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
kisS
Name Synonyms
of Spradling
Secondary FlyBase IDs
    References (3)