FlyBase Allele Report: Dmel\Antp[CB]

General Information

Symbol

Dmel\Antp^CB

Species

D. melanogaster

Name

FlyBase ID

FBal0000581

Feature type

allele

Associated gene

Dmel\Antp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

gain of function allele

Mutagen

X ray

Nature of the Allele

Allele class

gain of function allele

(Jorgensen and Garber, 1987)

Mutagen

X ray

(Scott et al., 1983)

Progenitor genotype

Caused by aberration

In(3R)Antp^CB

Cytology

Description

Proximal inversion breakpoint is at map position +198.

(Scott et al., 1983)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | dominant

(Abbott and Kaufman, 1986)

lethal | recessive

(Scott et al., 1983)

viable (with Antp¹)

(Southworth and Kennison, 2002)

viable (with Antp²³)

(Southworth and Kennison, 2002)

visible | dominant

(Jorgensen and Garber, 1987)

visible | homeotic

(Abbott and Kaufman, 1986)

Phenotype Manifest In

antenna

(Cribbs et al., 1995, Abbott and Kaufman, 1986, Scott et al., 1983)

mesothoracic leg | ectopic

(Cribbs et al., 1995)

Detailed Description

Statement

Reference

Transformation of head to thoracic tissue.

(Jorgensen and Garber, 1987)

Homeotic transformation of antennae to mesothoracic legs. Deficient for a dorsal thoracic function and retain normal leg specific function.

(Abbott and Kaufman, 1986)

Antennae to leg transformation.

(Scott et al., 1983)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Antp^CB, ct^L188 has visible phenotype

(Johnston et al., 1998)

Antp^CB, ct^C145 has visible phenotype

(Johnston et al., 1998)

Phenotype Manifest In

Other

Statement

Reference

Antp^CB, ct^L188 has humeral bristle phenotype

(Johnston et al., 1998)

Antp^CB, ct^L188 has pronotum phenotype

(Johnston et al., 1998)

Antp^CB, ct^L188 has postpronotum phenotype

(Johnston et al., 1998)

Antp^CB, ct^C145 has humeral bristle phenotype

(Johnston et al., 1998)

Antp^CB, ct^C145 has pronotum phenotype

(Johnston et al., 1998)

Antp^CB, ct^C145 has postpronotum phenotype

(Johnston et al., 1998)

Antp^CB, pb^hs.PB has antenna phenotype

(Cribbs et al., 1995)

Antp^CB, pb^hs.PB has maxillary palp | ectopic phenotype

(Cribbs et al., 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Homeotic transformation of antennae to T2 leg seen in Antp^CB flies can be redirected by pb^hs.PB from ectopic leg to maxillary palp, at any temperature between 22^oC and 29^oC.

(Cribbs et al., 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

2233

In(3R)Antp^CB, Antp^CB/TM3, Sb¹ Ser⁺

Notes on Origin

Discoverer

Black.

Comments

Moderate allele.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Antp^CB

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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