FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)BSC259
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General Information
Symbol
Df(2R)BSC259
Species
D. melanogaster
Name
FlyBase ID
FBab0045035
Feature type
chromosomal_deletion
Computed Breakpoints include

[48A3-48A3];[48C4-48C4];

Features within 48A3--48C4
Genomic Maps
Sequence coordinates
2R:11,593,011..11,593,011 (Df(2R)BSC259:bk1)
(Bloomington Drosophila Stock Center, 2008.8.7)
2R:11,823,771..11,823,771 (Df(2R)BSC259:bk2)
(Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)
Dfs_BSC_set2

A set of ~800 largely isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Designed to fill gaps in deletion coverage and breakpoint placement; also used to replace older available deficiencies that have not been molecularly mapped.

(Cook et al., 2012)
Nature of Aberration
Cytological Order
Progenitor
PBac{RB}e00138
(Christensen and Cook, 2007.3.22)
P{XP}toud07714
(Christensen and Cook, 2007.3.22)
Mutagen
FLPase
(Christensen and Cook, 2007.3.22)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Christensen and Cook, 2007.3.22)
Breakpoints

48A3;48C4

(FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions
P+PBac{XP5.RB3}BSC259
(Christensen and Cook, 2007.3.22)
Formalized genetic data
Genetic mapping information
Comments

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

(Bloomington Drosophila Stock Center, 2008.8.7)
Comments on Cytology

The cytological breakpoints of Df(2R)BSC259 predicted from the Release 4 genomic coordinates of the transposable element insertions sites are 48A3;48C4.

(Christensen and Cook, 2007.3.22)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
atos
(Emtenani et al., 2022)
wal
(Kahsai et al., 2016, Christensen and Cook, 2007.3.22)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (25)
Phenotypic Data
In combination with other aberrations

In Df(2R)BSC25/Df(2R)BSC259 (FGF8 null) mutant embryos (referred to as FGF8 null) the longitudinal gut musculature fails to form. A reduced number of LVM founder cells is seen in stage 11 embryos, and by stage 12 almost all of the founders lose contact with the trunk visceral mesoderm (TVM) rather than spreading out across it. By stage 13 the vast majority of these cells undergo cell death. The few cells that do survive are capable of producing a small number of LVM fibres.

(Reim et al., 2012)
NOT in combination with other aberrations
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The presence of Df(2R)BSC259 was verified using the PCR methods and primers described in FBrf0175003.

(Christensen and Cook, 2007.3.22)
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Df(2R)BSC259
(Emtenani et al., 2022, Kahsai et al., 2016, Cook et al., 2012, Reim et al., 2012, FlyBase Curators, 2008, Christensen and Cook, 2007.3.22, FlyBase, 2007)
Df(2R)FDD-0092408
(Cook and Ryder, 2007.5.14)
Name Synonyms
Secondary FlyBase IDs
    References (10)